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Proteintech
AXUD1 Polyclonal Antibody
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Product Details
18162-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AXUD1 Fusion Protein Ag6158 (239-589 aa encoded by BC038949)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: CHCDRICDP ETCSCSLAGI KCQMDHTAFP CGCCREGCEN PMGRVEFNQA RVQTHFIHTL TRLQLEQEAE SFRELEAPAQ GSPPSPGEEA LVPTFPLAKP PMNNELGDNS CSSDMTDSST ASSSASGTSE APDCPTHPGL PGPGFQPGVD DDSLARILSF SDSDFGGEEE EEEEGSVGNL DNLSCFHPAD IFGTSDPGGL ASWTHSYSGC SFTSGILDEN ANLDASCFLN GGLEGSREGS LPGTSVPPSM DAGRSSSVDL SLSSCDSFEL LQALPDYSLG PHYTSQKVSD SLDNIEAPHF PLPGLSPPGD ASSCFLESLM GFSEPAAEAL DPFIDSQFED TVPASLMEPV PV (239-589 aa encoded by BC038949)
Target Information
Axin, an important regulator of beta-catenin, is frequently mutated in human hepatocellular carcinomas (HCCs), and transduction of the wild-type Axin gene (AXIN1) induces apoptosis in HCC cells as well as in colon cancer cells. A novel gene, AXUD1 (AXIN1 up-regulated), has enhanced expression in response to exogenously expressed AXIN1. It is expressed in all human tissues examined, most abundantly in lung, placenta, skeletal muscle, pancreas and leukocytes. Data suggests that AXUD1 may have a tumor-suppressor function in those organs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Axin-1 up-regulated gene 1 protein; AXIN1 up-regulated 1; CSRNP-1; Cysteine/serine-rich nuclear protein 1; DKFZp566F164; Protein URAX1; TAIP-3; TGF-beta induced apoptosis protein 3; TGF-beta-induced apoptosis protein 3; URAX1; URAX1 protein
Gene Aliases: 4931429D10Rik; AXUD1; CSRNP-1; CSRNP1; FAM130B; TAIP-3; TAIP3; URAX1
UniProt ID: (Human) Q96S65, (Mouse) P59054
Entrez Gene ID: (Human) 64651, (Rat) 363165, (Mouse) 215418
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
post-embryonic development
positive regulation of transcription from RNA polymerase II promoter
platelet-derived growth factor receptor signaling pathway
skeletal system morphogenesis
palate development
face morphogenesis
transcription, DNA-templated
apoptotic process
regulation of transcription from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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