|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-21872 detects AXUD1 in human samples.
PA1-21872 has been successfully used in Western blot procedures.
PA1-21872 immunogen is AXUD1.
Axin, an important regulator of beta-catenin, is frequently mutated in human hepatocellular carcinomas (HCCs) and transduction of the wild-type Axin gene (AXIN1) induces apoptosis in HCC cells as well as in colon cancer cells. A novel gene, AXUD 1 (AXIN 1 up-regulated), has enhanced expression in response to exogenously expressed AXIN 1. It is expressed in all human tissues examined, most abundantly in lung, placenta, skeletal muscle, pancreas and leukocytes. Data suggests that AXUD 1 may have a tumor-supressor function in those organs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.