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Invitrogen
AZGP1 Polyclonal Antibody
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Product Details
PA5-75645
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues in Human AZGP1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
Alpha-2-glycoprotein 1, zinc-binding (AZGP1) is a gene encoding a protein that belongs to the immunoglobulin superfamily. This protein is abundant in various body fluids, such as blood plasma and milk, and is involved in lipid mobilization. AZGP1 is expressed in numerous tissues, including the liver, prostate, and adipose tissue, where it plays a significant role in the regulation of lipid metabolism and adipocyte function. It acts as an adipokine, influencing the breakdown and mobilization of fats, thereby contributing to energy homeostasis. In cancer research, AZGP1 has been highlighted for its potential as a prognostic biomarker, particularly in prostate and breast cancer, where lower expression levels are often associated with poor prognosis. Recent studies have also linked AZGP1 to cachexia, an extreme form of weight loss and muscle wasting, by promoting lipid mobilization in adipose tissue and influencing systemic catabolic states. Due to its multifaceted roles in lipid metabolism and disease processes, AZGP1 is considered a promising target for therapeutic interventions in metabolic and cancer-related disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-2 - glycoprotein 1 zinc; alpha-2 - glycoprotein 1, zinc; alpha-2-glycoprotein 1, zinc; Alpha-2-glycoprotein, zinc; major histocompatibility complex class I-like protein; testicular tissue protein Li 227; Zinc a 2 glycoprotein; Zinc a2glycoprotein; Zinc alpha2glycoprotein; Zinc α 2 glycoprotein; Zinc α2glycoprotein; Zinc-alpha-2-glycoprotein; Zn - alpha2 - glycoprotein; Zn a 2 glycoprotein; Zn a 2 GP; Zn alpha 2 glycoprotein; Zn alpha 2 GP; Zn α 2 glycoprotein; Zn α 2 GP; zn-alpha-2-glycoprotein; Zn-alpha-2-GP; Zn-alpha2-glycoprotein
Gene Aliases: AZGP1; ZA2G; ZA2GA; ZAG; Zna2gp; ZNGP1
UniProt ID: (Human) P25311, (Mouse) Q64726
Entrez Gene ID: (Human) 563, (Mouse) 12007, (Rat) 25294
detection of chemical stimulus involved in sensory perception of bitter taste
retina homeostasis
antigen processing and presentation of peptide antigen via MHC class I
immune response
cell adhesion
negative regulation of cell proliferation
antigen processing and presentation
transmembrane transport
protein transmembrane transport
RNA phosphodiester bond hydrolysis
regulation of multicellular organism growth
positive regulation of T cell mediated cytotoxicity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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