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This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.
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Protein Aliases: Acinus; Apoptotic chromatin condensation inducer in the nucleus; DKFZp667N107
Gene Aliases: 2610036I19Rik; 2610510L13Rik; Acin1; Acinus; acinusL; acinusS; Acn; C79325; mKIAA0670
UniProt ID: (Mouse) Q9JIX8
Entrez Gene ID: (Mouse) 56215
Molecular Function: protein modifying enzyme