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Bioss
Acrosin Polyclonal Antibody
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Product Details
BS-5151R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Goat,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Acrosin, amino acids 201-300.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acrosin; acrosin light and heavy chain prepropeptide; acrosin prepropeptide; preproacrosin; proacrosin
Gene Aliases: ACR; Acro; ACRS
UniProt ID: (Human) P10323, (Rat) P29293, (Mouse) P23578
Entrez Gene ID: (Goat) 102191416, (Human) 49, (Rat) 24163, (Mouse) 11434
protease binding
DNA binding
amidase activity
serine-type endopeptidase activity
copper ion binding
protein binding
mannose binding
drug binding
zinc ion binding
fucose binding
molecular_function
peptidase activity
serine-type peptidase activity
hydrolase activity
protease
serine protease
protein modifying enzyme
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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