This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. View Details
PA1-054 detects Adiponectin (30 kDa) from mouse serum.
PA1-054 has been successfully used in Western blot and immunoprecipitation procedures. By Western blot, this antibody detects an ~30 kDa protein representing Adiponectin from mouse serum.
The PA1-054 immunogen is a pair of synthetic peptides corresponding to the residues E(18) D D V T T T E E L A P A L V(32) and F(187) T Y D Q Y Q E K N V D Q A(200) of mouse Adiponectin.
Adiponectin is a protein hormone secreted exclusively by adipocytes that regulates the metabolism of lipids and glucose. Adiponectin has been shown to play a role in various physiological processes including homeostasis and obesity. Decreased levels of adiponectin are associated with obese individuals as well as insulin resistance and hyperinsulinemia (type 2 diabetes). In mice adiponectin has been shown to improve insulin signaling, thus ameliorating insulin resistance. Through activation of AMP kinase and PPAR-alpha, adiponectin can increase fatty acid transport, oxidation, and dissipation in skeletal muscle, leading to a reduction of intramyocellular lipid levels and thus improved insulin signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 30 kDa adipocyte complement-related protein; ACRP30; adipocyte complement related protein; Adipocyte complement-related 30 kDa protein; adipocyte, C1Q and collagen domain containing; Adipocyte, C1q and collagen domain-containing protein; Adipocyte-specific protein AdipoQ; Adiponectin; ADPIOQ
Gene Aliases: 30kDa; Acdc; Acrp30; Ad; adipo; Adipoq; Apm1; APN; GBP28
UniProt ID: (Mouse) Q60994
Entrez Gene ID: (Mouse) 11450