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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • alanyl-tRNA Synthetase Antibodies

          Proteintech

          AlaRS Polyclonal Antibody, CoraLite® Plus 488

          View all (10) alanyl-tRNA Synthetase antibodies

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          Cite AlaRS Polyclonal Antibody, CoraLite® Plus 488

          • Antibody Testing Data (2)
          AlaRS Antibody in Immunocytochemistry (ICC/IF)
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          AlaRS Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          AlaRS Antibody (CL488-17394) in ICC/IF

          Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using CoraLite® Plus 488 AlaRS antibody (CL488-17394) at dilution of 1:200, CL594-Phalloidin (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          AlaRS Antibody in Immunocytochemistry (ICC/IF)
          AlaRS Antibody in Flow Cytometry (Flow)

          Product Details

          CL488-17394

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          -

          Flow Cytometry (Flow)

          0.80 µg/10^6 cells in a 100 µL suspension
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          AlaRS fusion protein Ag11294

          Conjugate

          CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488

          Excitation/Emission Max

          493/522 nm

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 0.5% BSA, 50% glycerol

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: MDSTLTASE IRQRFIDFFK RNEHTYVHSS ATIPLDDPTL LFANAGMNQF KPIFLNTIDP SHPMAKLSRA ANTQKCIRAG GKHNDLDDVG KDVYHHTFFE MLGSWSFGDY FKELACKMAL ELLTQEFGIP IERLYVTYFG GDEAAGLEAD LECKQIWQNL GLDDTKILPG NMKDNFWEMG DTGPCGPCSE IHYDRIGGRD AAHLVNQDDP NVLEIWNLVF IQYNREADGI LKPLPKKSID TGMGLERLVS VLQNKMSNYD TDLFVPYFEA IQKGTGARPY TGKVGAEDAD GIDMAYRVLA DHARTITVAL ADGGRPDNTG RGYVLRRILR RAVRYAHEKL NASRGFFATL V

          Target Information

          The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E. coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: AARS; alanine tRNA ligase 1, cytoplasmic; Alanine--tRNA ligase, cytoplasmic; Alanyl-tRNA synthetase; alanyl-tRNA synthetase, cytoplasmic; AlaRS; Protein lactyltransferase AARS1; Renal carcinoma antigen NY-REN-42

          View more View less

          Gene Aliases: AARS; AARS1; CMT2N; EIEE29

          View more View less

          UniProt ID: (Human) P49588

          View more View less

          Entrez Gene ID: (Human) 16

          View more View less

          Function(s)
          tRNA binding aminoacyl-tRNA editing activity alanine-tRNA ligase activity ATP binding zinc ion binding amino acid binding aminoacyl-tRNA synthetase
          Process(es)
          hair follicle development tRNA modification tRNA aminoacylation for protein translation alanyl-tRNA aminoacylation regulation of translational fidelity protein folding tRNA processing cerebellar Purkinje cell layer development endoplasmic reticulum unfolded protein response response to amino acid negative regulation of neuron apoptotic process neuromuscular process controlling balance
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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