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Invitrogen
Alix Polyclonal Antibody
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Product Details
PA5-52873
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
C. elegans,
Human,
Mouse,
Nematode
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Alix. Recombinant protein control fragment (Product #RP-90648).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VPVSVQQSLA AYNQRKADLV NRSIAQMREA TTLANGVLAS LNLPAAIEDV SGDTVPQSIL TKSRSVIEQG GIQTVDQLIK ELPELLQRNR EILDESLRLL DEEEATDND
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
Target Information
Apoptotic linked-gene-product 2 (ALG-2) interacting protein X (ALIX) is a conserved adaptor protein which is ubiquitously expressed. Alix was originally reported to play a role in apoptosis but has recently been shown to be involved in other cellular mechanisms including endosomal sorting, endocytosis, viral budding and actin cytoskeleton assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ALG-2 interacting protein 1; ALG-2-interacting protein 1; ALG-2-interacting protein X; apoptosis-linked gene 2-interacting protein X; dopamine receptor interacting protein 4; Hp95; MGC17003; PDCD6-interacting protein; Programmed cell death 6-interacting protein
Gene Aliases: AIP1; ALIX; DRIP4; HP95; KIAA1375; PDCD6IP
UniProt ID: (Human) Q8WUM4
Entrez Gene ID: (Human) 10015
cell separation after cytokinesis
apoptotic process
nucleus organization
mitotic metaphase plate congression
regulation of centrosome duplication
protein transport
viral life cycle
multivesicular body assembly
viral budding via host ESCRT complex
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
regulation of mitotic spindle assembly
positive regulation of exosomal secretion
regulation of extracellular exosome assembly
positive regulation of extracellular exosome assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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