Immunogen sequence: RRPERGPRGK GKARASQVKP GDSLPRRGPG ATGIGTPAAG PGEERVGAAK
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Predicted homology: Cow: 92%; Dog: 85%; Guinea Pig: 79%; Human: 100%; Mouse: 79%; Pig: 85%; Rat: 79%
Alpha-2-adrenergic receptors (ADRA2A) are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. ADRA2A mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G protein. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system.
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Protein Aliases: adrenergic, alpha-2A-, receptor; Alpha-2 adrenergic receptor subtype C10; alpha-2-adrenergic receptor, platelet type; Alpha-2A adrenergic receptor; Alpha-2A adrenoceptor; Alpha-2A adrenoreceptor; alpha-2AAR subtype C10; OTTHUMP00000058849
Gene Aliases: ADRA2; ADRA2A; ADRA2R; ADRAR; ALPHA2AAR; ZNF32
UniProt ID: (Human) P08913
Entrez Gene ID: (Human) 150