This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Protein Aliases: actin-binding protein anillin; Anillin; anillin, actin binding protein; anillin, actin binding protein (scraps homolog, Drosophila); DKFZp779A055
Gene Aliases: 1110037A17Rik; 2900037I21Rik; ANLN; C78101; FSGS8; RGD1561367; scra; Scraps
Molecular Function: non-motor actin binding protein