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Proteintech
Anosmin-1 Polyclonal Antibody
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Product Details
26504-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anosmin-1 fusion protein Ag24188
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: QCSKCLEPCK ESGDLRKHQC QSFCEPLFPK KSYECLTSCE FLKYILLVKQ GDCPAPEKAS GFAAACVESC EVDNECSGVK KCCSNGCGHT CQVPKTLYKG VPLKPRKELR FTELQSGQLE VKWSSKFNIS IEPVIYVVQR RWNYGIHPSE DDATHWQTVA QTTDERVQLT DIRPSRWYQF RVAAVNVHGT RGFTAPSKHF RSSKDPSAPP APANLRLANS TVNSDGSVTV TIVWDLPEEP DIPVHHYKVF WSWMVSSKSL VPTKKKRRKT TDGFQNSVIL EKLQPDCDYV VELQAITYWG QTRLKSAKVS LHFTSTHATN NKEQLVKTR
Target Information
KAL1 (Anosmin-1) an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adhesion molecule-like X-linked; anosmin; Anosmin-1; Anosmin1; KAL; KALIG-1; Kallmann syndrome interval gene 1; Kallmann syndrome protein; Kallmann syndrome-1 sequence (anosmin-1); putative adhesion molecule; WAP four-disulfide core domain 19
Gene Aliases: ADMLX; ANOS1; HH1; HHA; KAL; KAL1; KALIG-1; KALIG1; KMS; WFDC19
UniProt ID: (Human) P23352
Entrez Gene ID: (Human) 3730
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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