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Product Details
APEL-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 25-77 on human Apelin protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AGTRL1 ligand; Apelin; apelin, AGTRL1 ligand; APJ endogenous ligand; preproapelin
Gene Aliases: 6030430G11Rik; APEL; APLN; XNPEP2
UniProt ID: (Human) Q9ULZ1, (Mouse) Q9R0R4, (Rat) Q9R0R3
Entrez Gene ID: (Human) 8862, (Mouse) 30878, (Rat) 58812
regulation of the force of heart contraction
immune response
signal transduction
lactation
positive regulation of cell proliferation
positive regulation of heat generation
positive regulation of phosphorylation
drinking behavior
regulation of respiratory gaseous exchange
negative regulation of blood pressure
negative regulation of vasoconstriction
positive regulation of vasodilation
positive regulation of corticotropin secretion
positive regulation of corticotropin-releasing hormone secretion
G-protein coupled receptor signaling pathway
feeding behavior
regulation of body fluid levels
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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