Invitrogen

Arginase 1 Polyclonal Antibody

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Arginase 1 Antibody in Immunohistochemistry (IHC) — Immunohistochemical analysis of Arginase 1 in human liver and kidney tissues using a Arginase 1 polyclonal antibody (Product # PA5-82106). Corresponding RNA-seq data are presented for the same tissues.

Arginase 1 Antibody in Western Blot (WB) — Western blot analysis of Arginase 1 by a Arginase 1 polyclonal antibody (Product # PA5-82106). Analysis in human liver tissue.

Product Details

Tested Applications

Dilution

Immunohistochemistry (Paraffin) (IHC (P))

1:2500-1:5000

Western Blot (WB)

0.4 µg/mL

Product Specifications

Species Reactivity

Human

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ARG1

Conjugate

Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Product Specific Information

Immunogen sequence: TIGIIGAPFS KGQPRGGVEE GPTVLRKAGL LEKLKEQECD VKDYGDLPFA DIPNDSPFQI VKNPRSVGKA SEQLAGKVAE VKKNGRISLV LGGDHSLAIG SISGHARVHP DLGVIWVDA

Target Information

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.