Keep as concentrated solution.
Positive Control: Huh7, HepG2, mouse liver, rat liver.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Arginase-1 (ARG1) catalyzes the hydrolysis of L-arginine into ornithine and urea, a critical step for the urea cycle. Defects in ARG1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia. There are several isoforms of mammalian arginase. The type I isoform, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Hepatocellular carcinoma usually shows higher protein expression of ARG1 than normal liver cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AI type I arginase; ARG1 antibody; arginase; arginase 1 antibody; arginase 1, liver; arginase I; arginase, liver; Arginase-1; liver antibody; Liver-type arginase; liver-type arginase antibody; Type I arginase; type I arginase antibody
Gene Aliases: AI; AI256583; Arg-1; ARG1; PGIF
Molecular Function: hydrolase