PA5-27879 targets Arp2 in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-27879 immunogen is recombinant fragment corresponding to a region within amino acids 40 and 341 of Human Arp2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Actin-like protein 2; Actin-related protein 2; ARP2; ARP2 actin-related protein 2 homolog
Gene Aliases: 4921510D23Rik; AA409782; ACTR2; ARP2; D6Ertd746e