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Invitrogen
Arp2 Polyclonal Antibody
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FIGURE: 1 / 4
Arp2 Antibody (PA5-27879) in IHC (P)
Arp2 Polyclonal Antibody detects Arp2 protein at cytosol on mouse stomach by immunohistochemical analysis. Sample: Paraffin-embedded mouse stomach. Arp2 Polyclonal Antibody (Product # PA5-27879) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-27879
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Fruit fly,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Arp2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.41 mg/mL
Amount
41 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: H1299, HeLa, HepG2, Molt-4, Raji, NIH-3T3.
Predicted reactivity: Mouse (100%), Rat (99%), Xenopus laevis (98%), Pig (100%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ARP2 (actin-related protein 2) is an ATP-binding component of the ARP2/3 complex - a multiprotein complex that mediates actin polymerization upon stimulation by the nucleation-promoting factor (NPF). The ARP2/3 complex mediates the formation of branched actin networks in the cytoplasm and provides the force for cell motility. The ARP2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Actin-like protein 14D; Actin-like protein 2; Actin-related protein 14 Da; Actin-related protein 14D; Actin-related protein 2; Arp14D; ARP2 actin related protein 2 homolog; ARP2 actin-related protein 2 homolog; Arp2-PA; Arp2-PB; Arp2-PC; CG9901-PA; CG9901-PB; CG9901-PC; LD18955p; one of seven subunits of the Arp2/3 protein complex; unnamed protein product
Gene Aliases: 4921510D23Rik; AA409782; Actr14D; ACTR2; ARP14D; ARP2; CG9901; D6Ertd746e; Dmel\CG9901; Dmel_CG9901
UniProt ID: (Human) P61160, (Rat) Q5M7U6, (Mouse) P61161, (Fruit fly) P45888
Entrez Gene ID: (Human) 10097, (Rat) 289820, (Mouse) 66713, (Fruit fly) 32623
establishment or maintenance of cell polarity
asymmetric cell division
positive regulation of lamellipodium assembly
meiotic chromosome movement towards spindle pole
cytosolic transport
actin cytoskeleton organization
meiotic cytokinesis
Arp2/3 complex-mediated actin nucleation
positive regulation of transcription from RNA polymerase II promoter
meiotic cell cycle
spindle localization
cilium morphogenesis
cellular response to interferon-gamma
positive regulation of double-strand break repair via homologous recombination
regulation of double-strand break repair via nonhomologous end joining
cilium assembly
actin filament organization
cell morphogenesis
positive regulation of synaptic growth at neuromuscular junction
regulation of filopodium assembly
terminal button organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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