The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.
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Protein Aliases: DCLRE1C protein; DNA cross-link repair 1A, PSO2 homolog; DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae); DNA cross-link repair 1C protein; FLJ11360; hSNM1C; mArt; Protein A-SCID; Protein artemis; RS SCID; severe combined immunodeficiency, type a (Athabascan); SNM1 homolog C; SNM1-like protein; SNM1C antibody; tein
Gene Aliases: 9930121L06Rik; A-SCID; AI661365; Art; ARTEMIS; ASCID; DCLRE1C; DCLREC1C; RS-SCID; SCIDA; SNM1C; Snm1l