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Bethyl Laboratories
Ataxin-7 Polyclonal Antibody
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FIGURE: 1 / 1
Ataxin-7 Antibody (A302-638A) in WB
Detection of human Ataxin-7 by western blot. Samples: Whole cell lysate (5, 15 and 50 µg) from HEK293T cells. Antibodies: Affinity purified rabbit anti-Ataxin-7 antibody (Product # A302-638A) used for WB at 0.4 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
Product Details
A302-638A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 842 and 892 of human spinocerebellar ataxia type 7.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Spinocerebellar ataxia type 7 (SCA7) belongs to a class of hereditary neurodegenrative diseases characterized by abnormally expanded polyglutamine (CAG) repeats at the N-terminus. This autosomal dominant cerebellar ataxia primarily affects the cerebellum, retina, and brain stem and causes dementia, macular degeneration and other neurodegenerative characteristics. SCA7 gene encodes the ubiquitous 892 residue protein ataxin-7. This protein is typically located in the cytoplasm and on the nuclear membrane of normal brain neurons. In cells where there is a mutation of the SCA7 gene, ataxin 7 accumulates in intranuclear inclusions and can result in cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ataxin-7; Autosomal dominant cerebellar ataxia with retinal degeneration; SAGA associated factor 73 kDa homolog; Spinocerebellar ataxia type 7 protein; unnamed protein product
Gene Aliases: ADCAII; ATXN7; OPCA3; SCA7; SGF73
UniProt ID: (Human) O15265
Entrez Gene ID: (Human) 6314
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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