Positive Control: human AXL-transfected 293T
Predicted Reactivity: Mouse (85%), Pig (81%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
AXL, a member of the AXL/UFO subfamily of Tyr protein kinases, may function as a signal transducer between specific cell types of mesodermal origin. This Type I membrane protein has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia. The protein contains 2 putative fibronectin type III domains and 2 putative immunoglobulin-like C2-type domains.
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Protein Aliases: AXL oncogene; AXL receptor tyrosine kinase; AXL transforming sequence/gene; JTK11; Tyrosine-protein kinase receptor UFO; UFO
Gene Aliases: ARK; AXL; JTK11; Tyro7; UFO
UniProt ID: (Human) P30530