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Proteintech
B-Myb Polyclonal Antibody
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Product Details
18896-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
B-Myb Fusion Protein Ag13525 (400-700 aa encoded by BC007585)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GSGIGTPPS VLKRQRKRRV ALSPVTENST SLSFLDSCNS LTPKSTPVKT LPFSPSQFLN FWNKQDTLEL ESPSLTSTPV CSQKVVVTTP LHRDKTPLHQ KHAAFVTPDQ KYSMDNTPHT PTPFKNALEK YGPLKPLPQT PHLEEDLKEV LRSEAGIELI IEDDIRPEKQ KRKPGLRRSP IKKVRKSLAL DIVDEDVKLM MSTLPKSLSL PTTAPSNSSS LTLSGIKEDN SLLNQGFLQA KPEKAAVAQK PRSHFTTPAP MSSAWKTVAC GGTRDQLFMQ EKARQLLGRL KPSHTSRTLI LS (400-700 aa encoded by BC007585)
Target Information
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: B Myb; B-Myb; HGNC:7548; MGC15600; Myb-like protein 2; Myb-related protein B; unnamed protein product; v-myb avian myeloblastosis viral oncogene homolog-like 2; v-myb myeloblastosis viral oncogene homolog-like 2
Gene Aliases: B-MYB; BMYB; MYBL2
UniProt ID: (Human) P10244, (Mouse) P48972
Entrez Gene ID: (Human) 4605, (Rat) 296344, (Mouse) 17865
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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