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Product Details
14177-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
B3GALT2 Fusion Protein Ag5384 (47-422 aa encoded by BC022507)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DWLPGRAGF KENPVTYTFR GFRSTKSETN HSSLRNIWKE TVPQTLRPQT ATNSNNTDLS PQGVTGLENT LSANGSIYNE KGTGHPNSYH FKYIINEPEK CQEKSPFLIL LIAAEPGQIE ARRAIRQTWG NESLAPGIQI TRIFLLGLSI KLNGYLQRAI LEESRQYHDI IQQEYLDTYY NLTIKTLMGM NWVATYCPHI PYVMKTDSDM FVNTEYLINK LLKPDLPPRH NYFTGYLMRG YAPNRNKDSK WYMPPDLYPS ERYPVFCSGT GYVFSGDLAE KIFKVSLGIR RLHLEDVYVG ICLAKLRIDP VPPPNEFVFN HWRVSYSSCK YSHLITSHQF QPSELIKYWN HLQQNKHNAC ANAAKEKAGR YRHRKLH (47-422 aa encoded by BC022507)
Target Information
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene encodes a protein that functions in N-linked glycoprotein glycosylation and shows strict donor substrate specificity for UDP-galactose.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-1,3-galactosyltransferase 2; Beta-1,3-GalTase 2; beta-3-galt2; beta3Gal-T2; beta3GalT2; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase 2; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase-II; UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2
Gene Aliases: B3GALT2; beta3Gal-T2; BETA3GALT2; GLCT2
UniProt ID: (Human) O43825, (Mouse) O54905
Entrez Gene ID: (Human) 8707, (Mouse) 26878, (Rat) 686081
UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
alpha-1,6-mannosyltransferase activity
alpha-1,2-mannosyltransferase activity
mannosyltransferase activity
alpha-1,3-mannosyltransferase activity
alpha-1,3-galactosyltransferase activity
UDP-glucose:glycoprotein glucosyltransferase activity
glycolipid mannosyltransferase activity
oligosaccharyl transferase activity
dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
acetylglucosaminyltransferase activity
acetylgalactosaminyltransferase activity
galactosyltransferase activity
fucosyltransferase activity
O antigen polymerase activity
lipopolysaccharide-1,6-galactosyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
cellulose synthase activity
9-phenanthrol UDP-glucuronosyltransferase activity
1-phenanthrol glycosyltransferase activity
9-phenanthrol glycosyltransferase activity
1,2-dihydroxy-phenanthrene glycosyltransferase activity
phenanthrol glycosyltransferase activity
beta-1,4-mannosyltransferase activity
alpha-1,2-galactosyltransferase activity
dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity
lipopolysaccharide-1,5-galactosyltransferase activity
dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity
dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity
inositol phosphoceramide synthase activity
glucosyltransferase activity
alpha-(1->3)-fucosyltransferase activity
alpha-(1->6)-fucosyltransferase activity
indole-3-butyrate beta-glucosyltransferase activity
salicylic acid glucosyltransferase (ester-forming) activity
salicylic acid glucosyltransferase (glucoside-forming) activity
benzoic acid glucosyltransferase activity
chondroitin hydrolase activity
dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity
cytokinin 9-beta-glucosyltransferase activity
glycosyltransferase
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