The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized.
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Protein Aliases: Beta-1,3-glucuronyltransferase 1; CD57; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; GlcAT-P; GLCATP; GlcUAT-P; GLCUATP; Glucuronosyltransferase P; glucuronosyltransferase-P; LEU7 antigen; NK-1; NK1; UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase
Gene Aliases: 0710007K08Rik; AI846286; B3GAT1; CD57; GlcAT-P; GLCATP; GLCUATP; Hnk-1; HNK1; LEU7; NK-1; NK1
Molecular Function: glycosyltransferase