Immunogen sequence: PVGLVGGRRY ERPLVENGKV VGWYTGWRAD RPFAIDMAGF AVSLQVILSN PKAVFKRRGS QPGMQESDFL KQITTVEELE PKANNCTKVL VWHTRTEKVN LANEPKYHLD TVK
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
The product of this gene is a transmembrane protein belonging to the glucuronyltransferase family, and catalyzes the transfer of a beta-1,3 linked glucuronic acid to a terminal galactose in different glycoproteins or glycolipids containing a Gal-beta-1-4GlcNAc or Gal-beta-1-3GlcNAc residue. The encoded protein is involved in the synthesis of the human natural killer-1 (HNK-1) carbohydrate epitope, a sulfated trisaccharide implicated in cellular migration and adhesion in the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Beta-1,3-glucuronyltransferase 2; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2; GlcAT-D; GlcAT-S; glucuronosyltransferase S; UDP-glucuronosyltransferase S; UDP-glucuronyltransferase S; uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase
Gene Aliases: B3GAT2; GLCATS; KIAA1963
UniProt ID: (Human) Q9NPZ5
Entrez Gene ID: (Human) 135152
Molecular Function: glycosyltransferase