PA5-29060 targets BAAT in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29060 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 254 of Human BAAT.
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The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
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Protein Aliases: BACAT; BAT; bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase); bile acid CoA:amino acid N-acyltransferase; bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase); Bile acid-CoA:amino acid N-acyltransferase; Glycine N-choloyltransferase; Long-chain fatty-acyl-CoA hydrolase
Gene Aliases: BAAT; BACAT; BAT
UniProt ID: (Human) Q14032
Entrez Gene ID: (Human) 570