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Invitrogen
BAAT Polyclonal Antibody
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Product Details
PA5-50362
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion protein corresponding to residues near the C terminal of human bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
Conjugate
Form
Liquid
Concentration
1.3 mg/mL
Amount
130 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total BAAT protein.
Target Information
The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BAAT; BACAT; bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase); bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase); Bile acid-CoA thioesterase; Bile acid-CoA:amino acid N-acyltransferase; bile acid-Coenzyme A dehydrogenase: amino acid n-acyltransferase; Choloyl-CoA hydrolase; Glycine N-choloyltransferase; Long-chain fatty-acyl-CoA hydrolase; taurine N-acyltransferase
Gene Aliases: AI118337; AI158864; BAAT; BACAT; BACD1; BAT; FHCA3; HCHO
UniProt ID: (Human) Q14032, (Mouse) Q91X34
Entrez Gene ID: (Human) 570, (Mouse) 12012
protein binding
N-acyltransferase activity
transferase activity
transferase activity, transferring acyl groups
hydrolase activity
thiolester hydrolase activity
choloyl-CoA hydrolase activity
acyl-CoA hydrolase activity
glycine N-choloyltransferase activity
carboxylic ester hydrolase activity
medium-chain acyl-CoA hydrolase activity
long-chain acyl-CoA hydrolase activity
very long chain acyl-CoA hydrolase activity
receptor binding
palmitoyl-CoA hydrolase activity
esterase
hydrolase
metabolite interconversion enzyme
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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