Immunogen sequence: YLFPIEEAQG QFLFIVGEGD KTINSKAHAE QAIGQLKRHG KNNWTLLSYP GAGHLIEPPY SPLCCASTTH DLRLHWGGEV IPHAAAQEHA WKEIQRFLRK HLIPDVTSQL; Positive Samples: Jurkat, BT-474, A-549, HepG2, Mouse liver, Rat liver; Cellular Location: Cytoplasm
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. This gene encodes a glycosylated cysteine protease inhibitor with a putative role in immune regulation through inhibition of a unique target in the hematopoietic system. Expression of the protein has been observed in various human cancer cell lines established from malignant tumors.
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Protein Aliases: BACAT; BAT; bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase); bile acid CoA:amino acid N-acyltransferase; bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase); Bile acid-CoA:amino acid N-acyltransferase; bile acid-Coenzyme A dehydrogenase: amino acid n-acyltransferase; bile acid-Coenzyme A: amino acid N-acyltransferase; Glycine N-choloyltransferase; Kan-1; Long-chain fatty-acyl-CoA hydrolase; taurine N-acyltransferase
Gene Aliases: AI118337; AI158864; BAAT; BACAT; BAT; kan-1