Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody can recognize all the isoforms of BAG1.
Immunogen sequence: PAQRGPPPS RRPPARSTAS GHDRPTRGAA AGARRPRMKK KTRRRSTRSE ELTRSEELTL SEEATWSEEA TQSEEATQGE EMNRSQEVTR DEESTRSEEV TREEMAAAGL TVTVTHSNEK HDLHVTSQQG SSEPVVQDLA QVVEEVIGVP QSFQKLIFKG KSLKEMETPL SALGIQDGCR VMLIGKKNSP QEEVELKKLK HLEKSVEKIA DQLEELNKEL TGIQQGFLPK DLQAEALCKL DRRVKATIEQ FMKILEEIDT LILPENFKDS RLKRKGLVKK VQAFLAECDT VEQNICQETE RLQSTNFALA E (36-345 aa encoded by BC014774)
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BAG family molecular chaperone regulator 1; BAG-1; Bcl-2 associating athanogene-1 protein; Bcl-2-associated athanogene 1; Bcl-2-binding protein; BCL2-associated athanogene; glucocortoid receptor-associated protein RAP46; receptor-associated protein, 46-KD; RP11-326F20.2
Gene Aliases: BAG-1; BAG1; HAP; RAP46
UniProt ID: (Human) Q99933, (Mouse) Q60739, (Rat) B0K019
Entrez Gene ID: (Human) 573, (Mouse) 12017, (Rat) 297994
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