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Proteintech
BAG1 Polyclonal Antibody
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Product Details
19064-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BAG1 Fusion Protein Ag13555 (36-345 aa encoded by BC014774)
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Amount
73.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can recognize all the isoforms of BAG1.
Immunogen sequence: PAQRGPPPS RRPPARSTAS GHDRPTRGAA AGARRPRMKK KTRRRSTRSE ELTRSEELTL SEEATWSEEA TQSEEATQGE EMNRSQEVTR DEESTRSEEV TREEMAAAGL TVTVTHSNEK HDLHVTSQQG SSEPVVQDLA QVVEEVIGVP QSFQKLIFKG KSLKEMETPL SALGIQDGCR VMLIGKKNSP QEEVELKKLK HLEKSVEKIA DQLEELNKEL TGIQQGFLPK DLQAEALCKL DRRVKATIEQ FMKILEEIDT LILPENFKDS RLKRKGLVKK VQAFLAECDT VEQNICQETE RLQSTNFALA E (36-345 aa encoded by BC014774)
Target Information
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BAG family molecular chaperone regulator 1; BAG-1; BAG-1L; Bcl-2 associating athanogene-1 protein; Bcl-2-associated athanogene 1; Bcl-2-binding protein; BCL2 associated athanogene 1; BCL2-associated athanogene; glucocortoid receptor-associated protein RAP46; receptor-associated protein, 46-KD; RP11-326F20.2
Gene Aliases: BAG-1; BAG1; HAP; RAP46
UniProt ID: (Human) Q99933, (Mouse) Q60739, (Rat) B0K019
Entrez Gene ID: (Human) 573, (Mouse) 12017, (Rat) 297994
negative regulation of protein phosphorylation
apoptotic process
neuron differentiation
negative regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of transcription from RNA polymerase II promoter
chaperone cofactor-dependent protein refolding
protein localization to mitochondrion
negative regulation of motor neuron apoptotic process
response to lithium ion
response to organic cyclic compound
response to nicotine
response to drug
protein folding
cell surface receptor signaling pathway
positive regulation of smooth muscle cell apoptotic process
protein stabilization
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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