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Proteintech
BAG1 Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-19064
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BAG1 fusion protein Ag13555
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: PAQRGPPPS RRPPARSTAS GHDRPTRGAA AGARRPRMKK KTRRRSTRSE ELTRSEELTL SEEATWSEEA TQSEEATQGE EMNRSQEVTR DEESTRSEEV TREEMAAAGL TVTVTHSNEK HDLHVTSQQG SSEPVVQDLA QVVEEVIGVP QSFQKLIFKG KSLKEMETPL SALGIQDGCR VMLIGKKNSP QEEVELKKLK HLEKSVEKIA DQLEELNKEL TGIQQGFLPK DLQAEALCKL DRRVKATIEQ FMKILEEIDT LILPENFKDS RLKRKGLVKK VQAFLAECDT VEQNICQETE RLQSTNFALA E
Target Information
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BAG family molecular chaperone regulator 1; BAG-1; Bcl-2 associating athanogene-1 protein; Bcl-2-associated athanogene 1; Bcl-2-binding protein; BCL2-associated athanogene; glucocortoid receptor-associated protein RAP46; receptor-associated protein, 46-KD; RP11-326F20.2
Gene Aliases: BAG-1; BAG1; HAP; RAP46
UniProt ID: (Human) Q99933, (Mouse) Q60739
Entrez Gene ID: (Human) 573, (Mouse) 12017
negative regulation of protein phosphorylation
apoptotic process
neuron differentiation
negative regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of transcription from RNA polymerase II promoter
chaperone cofactor-dependent protein refolding
protein localization to mitochondrion
negative regulation of motor neuron apoptotic process
cell surface receptor signaling pathway
regulation of catalytic activity
regulation of cellular response to heat
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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