Product References
Sequestosome 1 Deficiency Delays, but Does Not Prevent Brain Damage Formation Following Acute Brain Injury in Adult Mice.
Frontiers in neuroscience
Sebastiani A,Gölz C,Sebastiani PG,Bobkiewicz W,Behl C,Mittmann T,Thal SC,Engelhard K
Wed Sep 30 00:00:00 EDT 2020
Imbalances in protein homeostasis caused by mutant desmin.
Neuropathology and applied neurobiology
Winter L,Unger A,Berwanger C,Spörrer M,Türk M,Chevessier F,Strucksberg KH,Schlötzer-Schrehardt U,Wittig I,Goldmann WH,Marcus K,Linke WA,Clemen CS,Schröder R
Thu Aug 01 00:00:00 EDT 2019
Mitochondrial dysfunction in human immunodeficiency virus-1 transgenic mouse cardiac myocytes.
Journal of cellular physiology
Cheung JY,Gordon J,Wang J,Song J,Zhang XQ,Prado FJ,Shanmughapriya S,Rajan S,Tomar D,Tahrir FG,Gupta MK,Knezevic T,Merabova N,Kontos CD,McClung JM,Klotman PE,Madesh M,Khalili K,Feldman AM
Mon Apr 01 00:00:00 EDT 2019
Mitochondrial dysfunction in human immunodeficiency virus-1 transgenic mouse cardiac myocytes.
Journal of cellular physiology
Cheung JY,Gordon J,Wang J,Song J,Zhang XQ,Prado FJ,Shanmughapriya S,Rajan S,Tomar D,Tahrir FG,Gupta MK,Knezevic T,Merabova N,Kontos CD,McClung JM,Klotman PE,Madesh M,Khalili K,Feldman AM
Mon Apr 01 00:00:00 EDT 2019
A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology.
Nature neuroscience
Fu H,Possenti A,Freer R,Nakano Y,Hernandez Villegas NC,Tang M,Cauhy PVM,Lassus BA,Chen S,Fowler SL,Figueroa HY,Huey ED,Johnson GVW,Vendruscolo M,Duff KE
Tue Jan 01 00:00:00 EST 2019
The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?
Biochemical and biophysical research communications
Clemen CS,Winter L,Strucksberg KH,Berwanger C,Türk M,Kornblum C,Florin A,Aguilar-Pimentel JA,Amarie OV,Becker L,Garrett L,Hans W,Moreth K,Neff F,Pingen L,Rathkolb B,Rácz I,Rozman J,Treise I,Fuchs H,Gailus-Durner V,de Angelis MH,Vorgerd M,Eichinger L,Schröder R
Tue Sep 18 00:00:00 EDT 2018
Haplo-insufficiency of Bcl2-associated athanogene 3 in mice results in progressive left ventricular dysfunction, β-adrenergic insensitivity, and increased apoptosis.
Journal of cellular physiology
Myers VD,Tomar D,Madesh M,Wang J,Song J,Zhang XQ,Gupta MK,Tahrir FG,Gordon J,McClung JM,Kontos CD,Khalili K,Cheung JY,Feldman AM
Sat Sep 01 00:00:00 EDT 2018
Silencing of the Hsp70-specific nucleotide-exchange factor BAG3 corrects the F508del-CFTR variant by restoring autophagy.
The Journal of biological chemistry
Hutt DM,Mishra SK,Roth DM,Larsen MB,Angles F,Frizzell RA,Balch WE
Fri Aug 31 00:00:00 EDT 2018
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
International journal of medical sciences
Li XC,Hu QK,Chen L,Liu SY,Su S,Tao H,Zhang LN,Sun T,He LJ
Fri Jul 20 00:00:00 EDT 2018
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
International journal of medical sciences
Li XC,Hu QK,Chen L,Liu SY,Su S,Tao H,Zhang LN,Sun T,He LJ
Fri Jul 20 00:00:00 EDT 2018
Transcriptional upregulation of Bag3, a chaperone-assisted selective autophagy factor, in animal models of KY-deficient hereditary myopathy.
Disease models & mechanisms
Jokl EJ,Hughes GL,Cracknell T,Pownall ME,Blanco G
Fri Jul 06 00:00:00 EDT 2018
Dysregulated autophagy in restrictive cardiomyopathy due to Pro209Leu mutation in BAG3.
Molecular genetics and metabolism
Schänzer A,Rupp S,Gräf S,Zengeler D,Jux C,Akintürk H,Gulatz L,Mazhari N,Acker T,Van Coster R,Garvalov BK,Hahn A
Thu Mar 01 00:00:00 EST 2018
Dysregulated autophagy in restrictive cardiomyopathy due to Pro209Leu mutation in BAG3.
Molecular genetics and metabolism
Schänzer A,Rupp S,Gräf S,Zengeler D,Jux C,Akintürk H,Gulatz L,Mazhari N,Acker T,Van Coster R,Garvalov BK,Hahn A
Thu Mar 01 00:00:00 EST 2018
Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
Neurobiology of aging
Tang M,Ji C,Pallo S,Rahman I,Johnson GVW
Thu Mar 01 00:00:00 EST 2018
Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
Neurobiology of aging
Tang M,Ji C,Pallo S,Rahman I,Johnson GVW
Thu Mar 01 00:00:00 EST 2018
Transglutaminase type 2 plays a key role in the pathogenesis of Mycobacterium tuberculosis infection.
Journal of internal medicine
Palucci I,Matic I,Falasca L,Minerva M,Maulucci G,De Spirito M,Petruccioli E,Goletti D,Rossin F,Piacentini M,Delogu G
Thu Mar 01 00:00:00 EST 2018
Dysregulation of mitochondrial bioenergetics and quality control by HIV-1 Tat in cardiomyocytes.
Journal of cellular physiology
Tahrir FG,Shanmughapriya S,Ahooyi TM,Knezevic T,Gupta MK,Kontos CD,McClung JM,Madesh M,Gordon J,Feldman AM,Cheung JY,Khalili K
Thu Feb 01 00:00:00 EST 2018
Comparison of hepatic transcriptome profiling between acute liver injury and acute liver failure induced by acetaminophen in mice.
Toxicology letters
Li C,Ming Y,Hong W,Tang Y,Lei X,Li X,Mao Y
Thu Feb 01 00:00:00 EST 2018
A role of BAG3 in regulating SNCA/α-synuclein clearance via selective macroautophagy.
Neurobiology of aging
Cao YL,Yang YP,Mao CJ,Zhang XQ,Wang CT,Yang J,Lv DJ,Wang F,Hu LF,Liu CF
Fri Dec 01 00:00:00 EST 2017
A role of BAG3 in regulating SNCA/α-synuclein clearance via selective macroautophagy.
Neurobiology of aging
Cao YL,Yang YP,Mao CJ,Zhang XQ,Wang CT,Yang J,Lv DJ,Wang F,Hu LF,Liu CF
Fri Dec 01 00:00:00 EST 2017
Misfolded polypeptides are selectively recognized and transported toward aggresomes by a CED complex.
Nature communications
Park J,Park Y,Ryu I,Choi MH,Lee HJ,Oh N,Kim K,Kim KM,Choe J,Lee C,Baik JH,Kim YK
Wed Jun 07 00:00:00 EDT 2017
Evidence for the Role of BAG3 in Mitochondrial Quality Control in Cardiomyocytes.
Journal of cellular physiology
Tahrir FG,Knezevic T,Gupta MK,Gordon J,Cheung JY,Feldman AM,Khalili K
Sat Apr 01 00:00:00 EDT 2017
Evidence for the Role of BAG3 in Mitochondrial Quality Control in Cardiomyocytes.
Journal of cellular physiology
Tahrir FG,Knezevic T,Gupta MK,Gordon J,Cheung JY,Feldman AM,Khalili K
Sat Apr 01 00:00:00 EDT 2017
PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment.
Autophagy
Ma K,Fu W,Tang M,Zhang C,Hou T,Li R,Lu X,Wang Y,Zhou J,Li X,Zhang L,Wang L,Zhao Y,Zhu WG
Sat Mar 04 00:00:00 EST 2017
The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.
Biochimica et biophysica acta. Molecular cell research
Kathage B,Gehlert S,Ulbricht A,Lüdecke L,Tapia VE,Orfanos Z,Wenzel D,Bloch W,Volkmer R,Fleischmann BK,Fürst DO,Höhfeld J
Sun Jan 01 00:00:00 EST 2017
Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress.
PLoS pathogens
Liang J,Sagum CA,Bedford MT,Sidhu SS,Sudol M,Han Z,Harty RN
Sun Jan 01 00:00:00 EST 2017
Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress.
PLoS pathogens
Liang J,Sagum CA,Bedford MT,Sidhu SS,Sudol M,Han Z,Harty RN
Sun Jan 01 00:00:00 EST 2017
Adeno-associated Virus Serotype 9 - Driven Expression of BAG3 Improves Left Ventricular Function in Murine Hearts with Left Ventricular Dysfunction Secondary to a Myocardial Infarction.
JACC. Basic to translational science
Knezevic T,Myers VD,Su F,Wang J,Song J,Zhang XQ,Gao E,Gao G,Muniswamy M,Gupta MK,Gordon J,Weiner KN,Rabinowitz J,Ramsey FV,Tilley DG,Khalili K,Cheung JY,Feldman AM
Thu Dec 01 00:00:00 EST 2016
Adeno-associated Virus Serotype 9 - Driven Expression of BAG3 Improves Left Ventricular Function in Murine Hearts with Left Ventricular Dysfunction Secondary to a Myocardial Infarction.
JACC. Basic to translational science
Knezevic T,Myers VD,Su F,Wang J,Song J,Zhang XQ,Gao E,Gao G,Muniswamy M,Gupta MK,Gordon J,Weiner KN,Rabinowitz J,Ramsey FV,Tilley DG,Khalili K,Cheung JY,Feldman AM
Thu Dec 01 00:00:00 EST 2016
Bcl-2-associated athanogene 3 protects the heart from ischemia/reperfusion injury.
JCI insight
Su F,Myers VD,Knezevic T,Wang J,Gao E,Madesh M,Tahrir FG,Gupta MK,Gordon J,Rabinowitz J,Ramsey FV,Tilley DG,Khalili K,Cheung JY,Feldman AM
Thu Nov 17 00:00:00 EST 2016
Bcl-2-associated athanogene 3 protects the heart from ischemia/reperfusion injury.
JCI insight
Su F,Myers VD,Knezevic T,Wang J,Gao E,Madesh M,Tahrir FG,Gupta MK,Gordon J,Rabinowitz J,Ramsey FV,Tilley DG,Khalili K,Cheung JY,Feldman AM
Thu Nov 17 00:00:00 EST 2016
Transglutaminase type 2-dependent selective recruitment of proteins into exosomes under stressful cellular conditions.
Biochimica et biophysica acta
Diaz-Hidalgo L,Altuntas S,Rossin F,D'Eletto M,Marsella C,Farrace MG,Falasca L,Antonioli M,Fimia GM,Piacentini M
Mon Aug 01 00:00:00 EDT 2016
Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscle.
Autophagy
Ulbricht A,Gehlert S,Leciejewski B,Schiffer T,Bloch W,Höhfeld J
Mon Mar 07 00:00:00 EST 2016
Diagnostically important muscle pathology in DNAJB6 mutated LGMD1D.
Acta neuropathologica communications
Sandell S,Huovinen S,Palmio J,Raheem O,Lindfors M,Zhao F,Haapasalo H,Udd B
Fri Feb 05 00:00:00 EST 2016
Gold-nanorods-siRNA nanoplex for improved photothermal therapy by gene silencing.
Biomaterials
Wang BK,Yu XF,Wang JH,Li ZB,Li PH,Wang H,Song L,Chu PK,Li C
Mon Feb 01 00:00:00 EST 2016
Myofibrillar instability exacerbated by acute exercise in filaminopathy.
Human molecular genetics
Chevessier F,Schuld J,Orfanos Z,Plank AC,Wolf L,Maerkens A,Unger A,Schlötzer-Schrehardt U,Kley RA,Von Hörsten S,Marcus K,Linke WA,Vorgerd M,van der Ven PF,Fürst DO,Schröder R
Sun Dec 20 00:00:00 EST 2015
Myofibrillar instability exacerbated by acute exercise in filaminopathy.
Human molecular genetics
Chevessier F,Schuld J,Orfanos Z,Plank AC,Wolf L,Maerkens A,Unger A,Schlötzer-Schrehardt U,Kley RA,Von Hörsten S,Marcus K,Linke WA,Vorgerd M,van der Ven PF,Fürst DO,Schröder R
Sun Dec 20 00:00:00 EST 2015
The cleavage product of amyloid-β protein precursor sAβPPα modulates BAG3-dependent aggresome formation and enhances cellular proteasomal activity.
Journal of Alzheimer's disease : JAD
Renziehausen J,Hiebel C,Nagel H,Kundu A,Kins S,Kögel D,Behl C,Hajieva P
Mon Oct 26 00:00:00 EDT 2015
Cardiac Dysfunction in HIV-1 Transgenic Mouse: Role of Stress and BAG3.
Clinical and translational science
Cheung JY,Gordon J,Wang J,Song J,Zhang XQ,Tilley DG,Gao E,Koch WJ,Rabinowitz J,Klotman PE,Khalili K,Feldman AM
Sat Aug 01 00:00:00 EDT 2015
Chaperone molecules concentrate together with the ubiquitin-proteasome system inside particulate cytoplasmic structures: possible role in metabolism of misfolded proteins.
Histochemistry and cell biology
Vanoli A,Necchi V,Barozzi S,Manca R,Pecci A,Solcia E
Sat Aug 01 00:00:00 EDT 2015
Analysis of HDAC6 and BAG3-aggresome pathways in African swine fever viral factory formation.
Viruses
Muñoz-Moreno R,Barrado-Gil L,Galindo I,Alonso C
Wed Apr 08 00:00:00 EDT 2015
Analysis of HDAC6 and BAG3-aggresome pathways in African swine fever viral factory formation.
Viruses
Muñoz-Moreno R,Barrado-Gil L,Galindo I,Alonso C
Wed Apr 08 00:00:00 EDT 2015
WW domain of BAG3 is required for the induction of autophagy in glioma cells.
Journal of cellular physiology
Merabova N,Sariyer IK,Saribas AS,Knezevic T,Gordon J,Turco MC,Rosati A,Weaver M,Landry J,Khalili K
Wed Apr 01 00:00:00 EDT 2015
WW domain of BAG3 is required for the induction of autophagy in glioma cells.
Journal of cellular physiology
Merabova N,Sariyer IK,Saribas AS,Knezevic T,Gordon J,Turco MC,Rosati A,Weaver M,Landry J,Khalili K
Wed Apr 01 00:00:00 EDT 2015
BAG3 facilitates the clearance of endogenous tau in primary neurons.
Neurobiology of aging
Lei Z,Brizzee C,Johnson GV
Thu Jan 01 00:00:00 EST 2015
Decreased levels of BAG3 in a family with a rare variant and in idiopathic dilated cardiomyopathy.
Journal of cellular physiology
Feldman AM,Begay RL,Knezevic T,Myers VD,Slavov DB,Zhu W,Gowan K,Graw SL,Jones KL,Tilley DG,Coleman RC,Walinsky P,Cheung JY,Mestroni L,Khalili K,Taylor MR
Sat Nov 01 00:00:00 EDT 2014
Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics.
Molecular & cellular proteomics : MCP
Xue L,Wang P,Cao P,Zhu JK,Tao WA
Sat Nov 01 00:00:00 EDT 2014
Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics.
Molecular & cellular proteomics : MCP
Xue L,Wang P,Cao P,Zhu JK,Tao WA
Sat Nov 01 00:00:00 EDT 2014
14-3-3 protein targets misfolded chaperone-associated proteins to aggresomes.
Journal of cell science
Xu Z,Graham K,Foote M,Liang F,Rizkallah R,Hurt M,Wang Y,Wu Y,Zhou Y
Sun Sep 15 00:00:00 EDT 2013
Bag3-induced autophagy is associated with degradation of JCV oncoprotein, T-Ag.
PloS one
Sariyer IK,Merabova N,Patel PK,Knezevic T,Rosati A,Turco MC,Khalili K
Tue Mar 05 00:00:00 EST 2013
Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy.
Current biology : CB
Ulbricht A,Eppler FJ,Tapia VE,van der Ven PF,Hampe N,Hersch N,Vakeel P,Stadel D,Haas A,Saftig P,Behrends C,Fürst DO,Volkmer R,Hoffmann B,Kolanus W,Höhfeld J
Mon Mar 04 00:00:00 EST 2013
Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy.
Current biology : CB
Ulbricht A,Eppler FJ,Tapia VE,van der Ven PF,Hampe N,Hersch N,Vakeel P,Stadel D,Haas A,Saftig P,Behrends C,Fürst DO,Volkmer R,Hoffmann B,Kolanus W,Höhfeld J
Mon Mar 04 00:00:00 EST 2013
Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy.
Nature genetics
Sarparanta J,Jonson PH,Golzio C,Sandell S,Luque H,Screen M,McDonald K,Stajich JM,Mahjneh I,Vihola A,Raheem O,Penttilä S,Lehtinen S,Huovinen S,Palmio J,Tasca G,Ricci E,Hackman P,Hauser M,Katsanis N,Udd B
Sun Feb 26 00:00:00 EST 2012
Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy.
Nature genetics
Sarparanta J,Jonson PH,Golzio C,Sandell S,Luque H,Screen M,McDonald K,Stajich JM,Mahjneh I,Vihola A,Raheem O,Penttilä S,Lehtinen S,Huovinen S,Palmio J,Tasca G,Ricci E,Hackman P,Hauser M,Katsanis N,Udd B
Sun Feb 26 00:00:00 EST 2012
BAG3 expression in glioblastoma cells promotes accumulation of ubiquitinated clients in an Hsp70-dependent manner.
The Journal of biological chemistry
Gentilella A,Khalili K
Fri Mar 18 00:00:00 EDT 2011
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.
EMBO reports
Gamerdinger M,Kaya AM,Wolfrum U,Clement AM,Behl C
Tue Feb 01 00:00:00 EST 2011
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.
EMBO reports
Gamerdinger M,Kaya AM,Wolfrum U,Clement AM,Behl C
Tue Feb 01 00:00:00 EST 2011
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.
EMBO reports
Gamerdinger M,Kaya AM,Wolfrum U,Clement AM,Behl C
Tue Feb 01 00:00:00 EST 2011
The Hsc/Hsp70 co-chaperone network controls antigen aggregation and presentation during maturation of professional antigen presenting cells.
PloS one
Kettern N,Rogon C,Limmer A,Schild H,Höhfeld J
Thu Jan 20 00:00:00 EST 2011
The Hsc/Hsp70 co-chaperone network controls antigen aggregation and presentation during maturation of professional antigen presenting cells.
PloS one
Kettern N,Rogon C,Limmer A,Schild H,Höhfeld J
Thu Jan 20 00:00:00 EST 2011
Chaperone-assisted selective autophagy is essential for muscle maintenance.
Current biology : CB
Arndt V,Dick N,Tawo R,Dreiseidler M,Wenzel D,Hesse M,Fürst DO,Saftig P,Saint R,Fleischmann BK,Hoch M,Höhfeld J
Tue Jan 26 00:00:00 EST 2010
Autoregulation of co-chaperone BAG3 gene transcription.
Journal of cellular biochemistry
Gentilella A,Khalili K
Tue Dec 01 00:00:00 EST 2009
Autoregulation of co-chaperone BAG3 gene transcription.
Journal of cellular biochemistry
Gentilella A,Khalili K
Tue Dec 01 00:00:00 EST 2009