This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: INKLLKYLDL EEEADTTKAF DLRQNHSILK IEKVLKRMRE IKNELLQAQN PSELYLSSKT ELQGLIGQLD EVSLEKNPCI REARRRAVIE VQTLITYIDL KEALEKRKLF ACEEHPSHKA VWNVLGNLSE IQGEVLSFDG NRTDKNYIRL E
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 91%.
It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70's anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/ modulation of other BAG containing proteins via BAG-BAG heterodimerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BAG family molecular chaperone regulator 5; BAG-5; BAG-family molecular chaperone regulator-5; BAG-family molecular chaperone regulator-5 (BAG-5); Bcl-2-associated athanogene 5; BCL2-associated athanogene 5
Gene Aliases: 1600025G07Rik; 4930405J06Rik; BAG-5; BAG5; KIAA0873