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|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (SGSGTLVSTV) corresponding to the C-terminus amino acids of BAIAP2|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-3 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with mouse and rat based on sequence homology.
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor -binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
BAI1-associated protein 2; BAIAP2; BAP2; brain-specific angiogenesis inhibitor 1-associated protein 2; fas ligand-associated factor 3; FLAF3; insulin receptor substrate of 53 kDa; insulin receptor substrate p53; insulin receptor substrate p53/p58; insulin receptor substrate protein of 53 kDa; IRS-58; IRSP53; IRSp53/58
BAIAP2; BAP2; FLAF3; IRSP53