Immunogen sequence: MSQGLPAAGS VLQRSVAAPG NQPQPQPQQQ SPEDDDRKVR RREKNRVAAQ RSRKKQTQKA DKLHEEYESL EQENTMLRRE IGKLTEELKH LTEALKEHEK MCPLLLCPMN FVPVPPRPDP VAGCLPR; Positive Samples: Rat spleen; Cellular Location: Nucleus
BATF3, also known as SNFT, belongs to the basic leucine zipper transcriptional family and functions as a transcriptional repressor when heterodimerizing with Jun and can repress the transcription of IL-2 and MMP-1. BATF3 is required for the development of CD8alpha+ classical dendritic cells (DCs) and the related CD103+ DCs that cross-present antigens to CD8 T cells.
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Protein Aliases: B-ATF-3; Basic leucine zipper transcriptional factor ATF-like 3; JDP-1; Jun dimerization protein 1
Gene Aliases: Batf3; Jdp1
UniProt ID: (Rat) P97876
Entrez Gene ID: (Rat) 60462