Product References
Alleviative Effect of Lactoferrin Interventions Against the Hepatotoxicity Induced by Titanium Dioxide Nanoparticles.
Biological trace element research
Zhang W,Sun J,Liu F,Li S,Wang X,Su L,Liu G
Thu Feb 01 00:00:00 EST 2024
P7C3-A20 Attenuates Microglial Inflammation and Brain Injury after ICH through Activating the NAD+/Sirt3 Pathway.
Oxidative medicine and cellular longevity
Wu Y,Hu Q,Wu X,Cai YN,Zhang YZ,Wu YX,Zhu G,Luo JN,Cheng HB,Yu JG,Wang XL,Gao L,Gao GD
Wed Mar 01 00:00:00 EST 2023
BCKDHA contributes to melanoma progression by promoting the expressions of lipogenic enzymes FASN and ACLY.
Experimental dermatology
Tian Y,Ma J,Wang M,Yi X,Guo S,Wang H,Zhang H,Wang H,Yang Y,Zhang B,Du J,Shi Q,Gao T,Li C,Guo W
Sun Oct 01 00:00:00 EDT 2023
Laser-triggered intelligent drug delivery and anti-cancer photodynamic therapy using platelets as the vehicle.
Platelets
Li QR,Xu HZ,Xiao RC,Liu B,Ma TQ,Yu TT,Li LG,Wang MF,Zhao L,Chen X,Li TF
Fri Dec 01 00:00:00 EST 2023
Supramolecular nanofibers co-loaded with dabrafenib and doxorubicin for targeted and synergistic therapy of differentiated thyroid carcinoma.
Theranostics
Chen P,Cai X,Mu G,Duan Y,Jing C,Yang Z,Yang C,Wang X
Wed May 10 00:00:00 EDT 2023
Toll-like receptors (TLR2 and TLR4) antagonist mitigates the onset of cerebral small vessel disease through PI3K/Akt/GSK3β pathway in stroke-prone renovascular hypertensive rats.
Biotechnology & genetic engineering reviews
Wang N,Guo W,Liu T,Chen X,Lin M
Mon Mar 06 00:00:00 EST 2023
Alginate Oligosaccharides Prevent Dextran-Sulfate-Sodium-Induced Ulcerative Colitis via Enhancing Intestinal Barrier Function and Modulating Gut Microbiota.
Foods (Basel, Switzerland)
Wu A,Gao Y,Kan R,Ren P,Xue C,Kong B,Tang Q
Tue Jan 03 00:00:00 EST 2023
Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells.
Toxicology in vitro : an international journal published in association with BIBRA
Zhang L,Sun L,Wang L,Wang J,Wang D,Jiang J,Zhang J,Zhou Q
Sat Apr 01 00:00:00 EDT 2023
Photobiomodulation augments the effects of mitochondrial transplantation in the treatment of spinal cord injury in rats by facilitating mitochondrial transfer to neurons via Connexin 36.
Bioengineering & translational medicine
Zhu Z,Li X,Wang X,Zuo X,Ma Y,Gao X,Liang Z,Zhang Z,Song Z,Ding T,Ju C,Li P,Li K,Zhang J,Quan H,Wang Z,Hu X
Mon May 01 00:00:00 EDT 2023
5-Hydroxytryptophan inhibits β-casein biosynthesis and promotes goat mammary epithelial cell apoptosis through the JAK2/STAT5a axis and the HTR7.
Journal of animal science
Du W,Zhang ZF,Xiao JY,Wang Y,Liu WY,Zheng HL
Tue Jan 03 00:00:00 EST 2023
N-Acetylserotonin Protects Rat Nucleus Pulposus Cells Against Oxidative Stress Injury by Activating the PI3K/AKT Signaling Pathway.
World neurosurgery
Yidian W,Jihe K,Xudong G,Daxue Z,Mingqiang L,Xuewen K
Tue Aug 01 00:00:00 EDT 2023
Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritisin vivo.
Chinese journal of natural medicines
Teng L,Shen Y,Qu Y,Yang L,Yang Y,Jian X,Fan S,Zhang L,Fu Q
Wed Feb 01 00:00:00 EST 2023
Elevated PGT promotes proliferation and inhibits cell apoptosis in preeclampsia by Erk signaling pathway.
Molecular and cellular probes
Pang H,Lei D,Huang J,Guo Y,Fan C
Wed Feb 01 00:00:00 EST 2023
The Aldose Reductase Inhibitor Epalrestat Maintains Blood-Brain Barrier Integrity by Enhancing Endothelial Cell Function during Cerebral Ischemia.
Molecular neurobiology
Zhang T,Wu J,Yao X,Zhang Y,Wang Y,Han Y,Wu Y,Xu Z,Lan J,Han S,Zou H,Sun Q,Wang D,Zhang J,Wang G
Sat Jul 01 00:00:00 EDT 2023
Spleen Toxicity of Organophosphorus Flame Retardant TDCPP in Mice and the Related Mechanisms.
Toxics
Cao L,Wei L,Du Q,Su Y,Ye S,Liu K
Mon Feb 27 00:00:00 EST 2023
Stevioside protects primary articular chondrocytes against IL-1β-induced inflammation and catabolism by targeting integrin.
International immunopharmacology
Wan J,Zhu Z,He Z,Wu H,Chen A,Zhu W,Cheng P
Thu Jun 01 00:00:00 EDT 2023
Low temperature exposure inhibits proliferation and induces apoptosis of bovine subcutaneous preadipocytes via p38 MAPK/JNK activation.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Li T,Bai H,Yang L,Hao W,Wei S,Yan P
Tue Dec 20 00:00:00 EST 2022
6-Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF-7 cells by accumulating ROS to suppress the PI3K/AKT/mTOR signaling pathway.
Phytotherapy research : PTR
Zhang L,Zhang X,Che D,Zeng L,Zhang Y,Nan K,Zhang X,Zhang H,Guo Z
Sun Jan 01 00:00:00 EST 2023
Dioscin ameliorates silica-aggravated systemic lupus erythematosus via suppressing apoptosis and improving LC3-associated phagocytosis in MRL/lpr mice.
International immunopharmacology
Zhang P,Lei X,Ou L,Cheng Y,Miao Q,Li C,Chen Y
Wed Mar 01 00:00:00 EST 2023
Effect of doramectin on programmed cell death pathway in glioma cells.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Du S,Liang H,Zhou L,Chen C,Sun R,Zhang J,Meng X,Gao A
Sun Oct 01 00:00:00 EDT 2023
Effect of Lactobacillus delbrueckii subsp. lactis on vaginal radiotherapy for gynecological cancer.
Scientific reports
Bi Z,Wang Q,Yang T,Liu Y,Yuan J,Li L,Guo Y
Wed Jun 21 00:00:00 EDT 2023
Fucose ameliorates the proinflammatory property of Fusobacterium nucleatum in colitis via altering its metabolism.
Frontiers in cellular and infection microbiology
Duan C,Hou L,Deng X,Wu J,Qian W,Han C,Hou X
Fri May 19 00:00:00 EDT 2023
Phenolic profile, antioxidation and anti-proliferation activity of phenolic-rich extracts from Sanghuangporusvaninii.
Current research in food science
Gao H,Yin C,Li C,Li Y,Shi D,Fan X,Yao F,Wu W,Li J
Sun Jun 04 00:00:00 EDT 2023
Liraglutide Attenuates Hepatic Oxidative Stress, Inflammation, and Apoptosis in Streptozotocin-Induced Diabetic Mice by Modulating the Wnt/β-Catenin Signaling Pathway.
Mediators of inflammation
Yu J,Zhao Y,Xu L,Li W,Zhang H,Ping F,Li Y
Fri Feb 10 00:00:00 EST 2023
Andrographolide alleviates paraquat-induced acute lung injury by activating the Nrf2/HO-1 pathway.
Iranian journal of basic medical sciences
Zhang D,Shen F,Ma S,Nan S,Ma Y,Ren L,Li H,Yu Q
Wed Jun 07 00:00:00 EDT 2023
Oral exposure to polystyrene nanoplastics reduced male fertility and even caused male infertility by inducing testicular and sperm toxicities in mice.
Journal of hazardous materials
Xu W,Yuan Y,Tian Y,Cheng C,Chen Y,Zeng L,Yuan Y,Li D,Zheng L,Luo T
Sat Jul 15 00:00:00 EDT 2023
GDNF-Loaded Polydopamine Nanoparticles-Based Anisotropic Scaffolds Promote Spinal Cord Repair by Modulating Inhibitory Microenvironment.
Advanced healthcare materials
Ma J,Li J,Wang X,Li M,Teng W,Tao Z,Xie J,Ma Y,Shi Q,Li B
Wed Mar 01 00:00:00 EST 2023
Exosomal HSP90 induced by remote ischemic preconditioning alleviates myocardial ischemia/reperfusion injury by inhibiting complement activation and inflammation.
BMC cardiovascular disorders
Cheng XF,He ST,Zhong GQ,Meng JJ,Wang M,Bi Q,Tu RH
Wed Feb 01 00:00:00 EST 2023
SKA1 is overexpressed in laryngocarcinoma and modulates cell growth via P53 signaling pathway.
Cell cycle (Georgetown, Tex.)
Li Z,Liu J,Peng H,Li C,Liu Y,Xie W
Wed Mar 01 00:00:00 EST 2023
Disruption of the Intestinal Mucosal Barrier Induced by High Fructose and Restraint Stress Is Regulated by the Intestinal Microbiota and Microbiota Metabolites.
Microbiology spectrum
Yu J,Liu T,Guo Q,Wang Z,Chen Y,Dong Y
Tue Jan 31 00:00:00 EST 2023
Photobiomodulation treatment inhibits neurotoxic astrocytic polarization and protects neurons in in vitro and in vivo stroke models.
Neurochemistry international
Feng Y,Yang L,Ma X,Huang Z,Zong X,Citadin CT,Lin HW,Zhang Q
Sun Jan 01 00:00:00 EST 2023
Mini-αA Upregulates the miR-155-5p Target Gene CDK2 and Plays an Antiapoptotic Role in Retinal Pigment Epithelial Cells during Oxidative Stress.
Journal of ophthalmology
Chen Q,Lin H,Li S,Deng X,Zhang J
Sun Feb 26 00:00:00 EST 2023
ZYY-B-2, a novel ALK inhibitor, overcomes resistance to ceritinib by inhibiting P-gp function and induces apoptosis through mitochondrial pathway in ceritinib-resistant H2228 cells.
Chemico-biological interactions
Gao Y,Liu T,Liu J,Yang Y,Sun K,Li Z,Zhai X,Zuo D
Sat Jul 01 00:00:00 EDT 2023
Zearalenone induces oxidative stress and autophagy in goat Sertoli cells.
Ecotoxicology and environmental safety
Liu X,Xi H,Han S,Zhang H,Hu J
Wed Mar 01 00:00:00 EST 2023
Riboflavin protects against heart failure via SCAD-dependent DJ-1-Keap1-Nrf2 signalling pathway.
British journal of pharmacology
Xu Q,Cao Y,Zhong X,Qin X,Feng J,Peng H,Su Y,Ma Z,Zhou S
Fri Dec 01 00:00:00 EST 2023
Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis.
Veterinary research
Feng L,Luo G,Li Y,Zhang C,Liu Y,Liu Y,Chen H,He D,Zhu Y,Gan L
Tue Mar 14 00:00:00 EDT 2023
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Experimental cell research
Jia Y,Huang X,Shi H,Wang M,Chen J,Zhang H,Hou D,Jing H,Du J,Han H,Zhang J
Tue Aug 15 00:00:00 EDT 2023
Solanine Represses Gastric Cancer Growth by Mediating Autophagy Through AAMDC/MYC/ATF4/Sesn2 Signaling Pathway.
Drug design, development and therapy
Tang X,Guo Y,Zhang S,Wang X,Teng Y,Jin Q,Jin Q,Shen W,Wang R
Thu Feb 16 00:00:00 EST 2023
Mir-153-3p Modulates the Breast Cancer Cells' Chemosensitivity to Doxorubicin by Targeting KIF20A.
Cancers
Rahman KU,Yang S,Azam N,Yuan Z,Yu J,Zhao C,Feng B
Sat Mar 11 00:00:00 EST 2023
Pharmacological network analysis of the functions and mechanism of kaempferol from Du Zhong in intervertebral disc degeneration (IDD).
Journal of orthopaedic translation
Wang X,Tan Y,Liu F,Wang J,Liu F,Zhang Q,Li J
Wed Mar 01 00:00:00 EST 2023
Hypobaric Hypoxia Aggravates Renal Injury by Inducing the Formation of Neutrophil Extracellular Traps through the NF-κB Signaling Pathway.
Current medical science
Wei JY,Hu MY,Chen XQ,Wei JS,Chen J,Qin XK,Lei FY,Zou JS,Zhu SQ,Qin YH
Thu Jun 01 00:00:00 EDT 2023
Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization.
Neural regeneration research
Yu Y,Xia LK,Di Y,Nie QZ,Chen XL
Mon May 01 00:00:00 EDT 2023
Geranylgeranylacetone-induced heat shock protein70 expression reduces retinal ischemia-reperfusion injury through PI3K/AKT/mTOR signaling.
Experimental eye research
Zhang L,Xue K,Fan P,Chen C,Hu J,Huang J,Lu W,Xu J,Xu S,Ran J,Zhu S,Gan S
Sat Apr 01 00:00:00 EDT 2023
Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress.
World journal of gastroenterology
Hou XX,Li YW,Song JL,Zhang W,Liu R,Yuan H,Feng TT,Jiang ZY,Li WT,Zhu CL
Sun May 07 00:00:00 EDT 2023
FZD7, Regulated by Non-CpG Methylation, Plays an Important Role in Immature Porcine Sertoli Cell Proliferation.
International journal of molecular sciences
Yang A,Yan S,Yin Y,Chen C,Tang X,Ran M,Chen B
Fri Mar 24 00:00:00 EDT 2023
AAZ2 induces mitochondrial-dependent apoptosis by targeting PDK1 in gastric cancer.
Journal of Zhejiang University. Science. B
Li Y,She W,Xu X,Liu Y,Wang X,Tian S,Li S,Wang M,Yu C,Liu P,Huang T,Wei Y
Wed Mar 15 00:00:00 EDT 2023
Neuroprotective effects of oxymatrine on hypoxic-ischemic brain damage in neonatal rats by activating the Wnt/β-catenin pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lan XB,Ni YS,Liu N,Wei W,Liu Y,Yang JM,Ma L,Bai R,Zhang J,Yu JQ
Wed Mar 01 00:00:00 EST 2023
C11orf54 promotes DNA repair via blocking CMA-mediated degradation of HIF1A.
Communications biology
Tan J,Wang W,Liu X,Xu J,Che Y,Liu Y,Hu J,Hu L,Li J,Zhou Q
Mon Jun 05 00:00:00 EDT 2023
Aa-Z2 triggers ROS-induced apoptosis of osteosarcoma by targeting PDK-1.
Journal of translational medicine
Liu Y,She W,Li Y,Wang M,Liu Y,Ning B,Xu T,Huang T,Wei Y
Sat Jan 07 00:00:00 EST 2023
Design, Synthesis and Antitumor Activity of 1H-indazole-3-amine Derivatives.
International journal of molecular sciences
Wang C,Zhu M,Long X,Wang Q,Wang Z,Ouyang G
Fri May 12 00:00:00 EDT 2023
Inhibition of autophagic flux by the curcumin analog EF-24 and its antiproliferative effect on MCF-7 cancer cells.
Journal of biochemical and molecular toxicology
Li J,Wang SH,Liu YT,Zhang Q,Zhou GZ
Sat Apr 01 00:00:00 EDT 2023
Cinepazide maleate promotes recovery from spinal cord injury by inhibiting inflammation and prolonging neuronal survival.
Drug development research
Li D,Zhao S,Zhu B,Zhao W,Ding Y,Li X,Fu D,Yu H,Wang B,Pan T
Thu Jun 01 00:00:00 EDT 2023
Apelin-Overexpressing Neural Stem Cells in Conjunction with a Silk Fibroin Nanofiber Scaffold for the Treatment of Traumatic Brain Injury.
Stem cells and development
Li T,Tang Q,Xu J,Ye X,Chen K,Zhong J,Zhu J,Lu S,Zhu T
Fri Sep 01 00:00:00 EDT 2023
ALKBH5 ALLEVIATES HYPOXIA POSTCONDITIONING INJURY IN d -GALACTOSE-INDUCED SENESCENT CARDIOMYOCYTES BY REGULATING STAT3.
Shock (Augusta, Ga.)
Zhang X,Li F,Ma J,Zhang X,Yin Y
Sun Jan 01 00:00:00 EST 2023
Decreased AGGF1 facilitates the progression of placenta accreta spectrum via mediating the P53 signaling pathway under the regulation of miR-1296-5p.
Reproductive biology
Wang R,Zhao J,Liu C,Li S,Liu W,Cao Q
Wed Mar 01 00:00:00 EST 2023
Combined effects of EMP and RF field on emotional behavior in mice.
Frontiers in public health
Qin T,Liu L,Wang X,Guo L,Lin J,Du J,Xue Y,Lai P,Jing Y,Ding G
Tue Apr 04 00:00:00 EDT 2023
Methylseleninic acid induces apoptosis of human bladder cancer cells through the ROS-mediated mitochondrial pathway.
Journal of biochemical and molecular toxicology
Chen Y,Zhang Y,Wang X,Qiao S
Tue Aug 01 00:00:00 EDT 2023
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
The American journal of pathology
Chen X,Song QL,Wang JY,Ji R,Li ZH,Cao ML,Mu XF,Guo DY,Zhang Y,Yang J
Tue Aug 01 00:00:00 EDT 2023
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
Annals of translational medicine
Zhang N,Wang F,Zhu L,Chang R,Mok SRS,Peixoto RD,Tang W,Chen Z
Sun Jan 15 00:00:00 EST 2023
Adjuvant therapy with Huatan Sanjie Granules improves the prognosis of patients with primary liver cancer: a cohort study and the investigation of its mechanism of action based on network pharmacology.
Frontiers in pharmacology
Yuan J,Abdurahman A,Cui N,Hao T,Zou J,Liu L,Wu Y
Mon Jun 19 00:00:00 EDT 2023
Berberine promotes the viability of random skin flaps via the PI3K/Akt/eNOS signaling pathway.
Phytotherapy research : PTR
Chen J,Jiang Z,Liu X,Wang K,Fan W,Chen T,Li Z,Lin D
Wed Feb 01 00:00:00 EST 2023
Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia.
bioRxiv : the preprint server for biology
Ferrer M,Mourikis N,Davidson EE,Kleeman SO,Zaccaria M,Habel J,Rubino R,Flint TR,Connell CM,Lukey MJ,White EP,Coll AP,Venkitaraman AR,Janowitz T
Sat Feb 18 00:00:00 EST 2023
The alkaloids of Corydalis hendersonii Hemsl. contribute to the cardioprotective effect against ischemic injury in mice by attenuating cardiomyocyte apoptosis via p38 MAPK signaling pathway.
Chinese medicine
Ge F,Gao X,Zhou X,Li J,Ma X,Huang M,Wuken S,Tu P,An C,Chai X
Fri Mar 17 00:00:00 EDT 2023
The alkaloids of Corydalis hendersonii Hemsl. contribute to the cardioprotective effect against ischemic injury in mice by attenuating cardiomyocyte apoptosis via p38 MAPK signaling pathway.
Chinese medicine
Ge F,Gao X,Zhou X,Li J,Ma X,Huang M,Wuken S,Tu P,An C,Chai X
Fri Mar 17 00:00:00 EDT 2023
The alkaloids of Corydalis hendersonii Hemsl. contribute to the cardioprotective effect against ischemic injury in mice by attenuating cardiomyocyte apoptosis via p38 MAPK signaling pathway.
Chinese medicine
Ge F,Gao X,Zhou X,Li J,Ma X,Huang M,Wuken S,Tu P,An C,Chai X
Fri Mar 17 00:00:00 EDT 2023
The alkaloids of Corydalis hendersonii Hemsl. contribute to the cardioprotective effect against ischemic injury in mice by attenuating cardiomyocyte apoptosis via p38 MAPK signaling pathway.
Chinese medicine
Ge F,Gao X,Zhou X,Li J,Ma X,Huang M,Wuken S,Tu P,An C,Chai X
Fri Mar 17 00:00:00 EDT 2023
Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis.
Naunyn-Schmiedeberg's archives of pharmacology
Wei Y,Sun L,Liu C,Li L
Thu Jun 01 00:00:00 EDT 2023
Exploring the potential of ginseng glycoprotein to improve learning and memory in mice via Notch signaling pathway and structural analysis using multi-information fusion based on liquid chromatography-mass spectrometry.
Journal of ethnopharmacology
Fang X,Zhang X,Zhang Y,Zhang X,Shan M,Guan S,Qiu Z,Zhu D,Luo H
Wed Mar 01 00:00:00 EST 2023
20S-Protopanaxatriol improves cognitive function of Alzheimer's disease by promoting endogenous neurogenesis.
Food & function
Zhang Q,Yang X,Liu J,Song J,Zhang S,Chen L,Zhang M
Thu May 11 00:00:00 EDT 2023
Biomarkers based on multiplatform comprehensive analysis: A systematic analysis of Geng-Nian-Shu in perimenopausal syndrome.
Journal of separation science
Lv X,Xu Q,Zhang Z,Wang J,Wan M,Zhang X,Wu B,Yan T,Jia Y
Fri Sep 01 00:00:00 EDT 2023
The role of NADPH oxidase 1 in alcohol-induced oxidative stress injury of intestinal epithelial cells.
Cell biology and toxicology
Chen L,Chu H,Hu L,Li Z,Yang L,Hou X
Sun Oct 01 00:00:00 EDT 2023
GRIN2D knockdown suppresses the progression of lung adenocarcinoma by regulating the E2F signalling pathway.
Cellular signalling
Chen Z,Song Y,Li P,Gao W
Sat Jul 01 00:00:00 EDT 2023
Taxifolin ameliorates cigarette smoke-induced chronic obstructive pulmonary disease via inhibiting inflammation and apoptosis.
International immunopharmacology
Liu X,Ma Y,Luo L,Zeng Z,Zong D,Chen Y
Wed Feb 01 00:00:00 EST 2023
RBM3 is associated with acute lung injury in septic mice and patients via the NF-κB/NLRP3 pathway.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Long F,Hu L,Chen Y,Duan X,Xie K,Feng J,Wang M
Sat Apr 01 00:00:00 EDT 2023
Knockdown of kinesin family member 4A inhibits cell proliferation, migration, and invasion while promoting apoptosis of urothelial bladder carcinoma cells.
Cancer medicine
Zhang C,Wang M,Ying Y,Meng F,Gao H,Zeng S,Zhu Y,Liu A,Zhang Z,Xu C
Thu Jun 01 00:00:00 EDT 2023
Loss of pleckstrin homology domain and leucine-rich repeat protein phosphatase 2 has protective effects on high glucose-injured retinal ganglion cells via the effect on the Akt-GSK-3β-Nrf2 pathway.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Liu X,Liu Y,Chen L,Zhang Z,Cui L,Wei T
Wed Mar 01 00:00:00 EST 2023
Acupuncture regulates the apoptosis of ovarian granulosa cells in polycystic ovarian syndrome-related abnormal follicular development through LncMEG3-mediated inhibition of miR-21-3p.
Biological research
Chen X,He H,Long B,Wei B,Yang P,Huang X,Wang Q,Lin J,Tang H
Mon Jun 12 00:00:00 EDT 2023
Discovery of rafoxanide as a novel agent for the treatment of non-small cell lung cancer.
Scientific reports
Hu A,Liu J,Wang Y,Zhang M,Guo Y,Qin Y,Liu T,Men Y,Chen Q,Liu T
Fri Jan 13 00:00:00 EST 2023
Sesn2 Serves as a Regulator between Mitochondrial Unfolded Protein Response and Mitophagy in Intervertebral Disc Degeneration.
International journal of biological sciences
Xu WN,Liu C,Zheng HL,Xu HX,Yang RZ,Jiang SD,Zhu LX
Thu Feb 09 00:00:00 EST 2023
Semaglutide inhibits ischemia/reperfusion-induced cardiomyocyte apoptosis through activating PKG/PKCε/ERK1/2 pathway.
Biochemical and biophysical research communications
Zhu Q,Luo Y,Wen Y,Wang D,Li J,Fan Z
Sun Mar 05 00:00:00 EST 2023
Metabolomic analysis and pharmacological validation of the cerebral protective effect of 3,4‑dihydroxybenzaldehyde on cerebral ischemia‑reperfusion injury.
Molecular medicine reports
Luo Y,Chen P,Yang L,Duan X
Sun Jan 01 00:00:00 EST 2023
Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening.
Cell death discovery
Deng L,Yang L,Zhu S,Li M,Wang Y,Cao X,Wang Q,Guo L
Thu Feb 02 00:00:00 EST 2023
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
Experimental cell research
He W,Tong G,Fan H,Zhen C,Zeng L,Xue L,Chen J,Sun Z,He P
Wed Feb 15 00:00:00 EST 2023
Baicalin and baicalein attenuate hyperuricemic nephropathy via inhibiting PI3K/AKT/NF-κB signalling pathway.
Nephrology (Carlton, Vic.)
Liu Z,Xiang H,Deng Q,Fu W,Li Y,Yu Z,Qiu Y,Mei Z,Xu L
Thu Jun 01 00:00:00 EDT 2023
Melatonin reduces IL-33 and TSLP expression in human nasal epithelial cells by scavenging ROS directly.
Immunity, inflammation and disease
Gong MJ,Zhang HB,Lou M,Wang YS,Ma RP,Hu ZZ,Zheng GX,Zhang Y
Wed Feb 01 00:00:00 EST 2023
Inhibition of endogenous hydrogen sulfide production suppresses the growth of nasopharyngeal carcinoma cells.
Molecular carcinogenesis
Wang DY,Zhang J,Li HX,Zhang YX,Jing MR,Cai CB,Wang D,Qi HW,Wang YZ,Chen HJ,Li T,Zhai YK,Ji XY,Wu DD
Mon May 01 00:00:00 EDT 2023
O-linked N-acetylglucosamine affects mitochondrial homeostasis by regulating Parkin-dependent mitophagy in hyperoxia-injured alveolar type II cells injury.
Respiratory research
Xuefei Y,Dongyan L,Tianming L,Hejuan Z,Jianhua F
Mon Jan 16 00:00:00 EST 2023
Autophagy-Targeted Calcium Phosphate Nanoparticles Enable Transarterial Chemoembolization for Enhanced Cancer Therapy.
ACS applied materials & interfaces
Yuan G,Xu Y,Bai X,Wang W,Wu X,Chen J,Li J,Jia X,Gu Z,Zhang X,Hu W,Wang J,Liu Y,Zhu XM
Wed Mar 08 00:00:00 EST 2023
Protective effect of pinocembrin from Penthorum chinense Pursh on hepatic ischemia reperfusion injury via regulating HMGB1/TLR4 signal pathway.
Phytotherapy research : PTR
Ma T,Zhang H,Li T,Bai J,Wu Z,Cai T,Chen Y,Xia X,Du Y,Fu W
Sun Jan 01 00:00:00 EST 2023
TGF-β3 Protects Neurons Against Intermittent Hypoxia-Induced Oxidative Stress and Apoptosis Through Activation of the Nrf-2/KEAP1/HO-1 Pathway via Binding to TGF-βRI.
Neurochemical research
Huang Y,Liu Z,Wang X,Li Y,Liu L,Li B
Fri Sep 01 00:00:00 EDT 2023
Characterization of LTr1 derived from cruciferous vegetables as a novel anti-glioma agent via inhibiting TrkA/PI3K/AKT pathway.
Acta pharmacologica Sinica
Song QQ,Lin LP,Chen YL,Qian JC,Wei K,Su JW,Ding JH,Lu M,Liu Y,Tan RX,Hu G
Thu Jun 01 00:00:00 EDT 2023
Human kidney organoids model of Esculentoside A nephrotoxicity to investigate the role of epithelial-mesenchymal transition via STING signaling.
Toxicology letters
Gu S,Wu G,Lu D,Wang Y,Tang L,Zhang W
Sun Jan 15 00:00:00 EST 2023
Oridonin ameliorates caspase-9-mediated brain neuronal apoptosis in mouse with ischemic stroke by inhibiting RIPK3-mediated mitophagy.
Acta pharmacologica Sinica
Li L,Song JJ,Zhang MX,Zhang HW,Zhu HY,Guo W,Pan CL,Liu X,Xu L,Zhang ZY
Sat Apr 01 00:00:00 EDT 2023
GAS6/Axl is associated with AMPK activation and attenuates H2O2-induced oxidative stress.
Apoptosis : an international journal on programmed cell death
Liang Z,Yang Y,Wu X,Lu C,Zhao H,Chen K,Zhao A,Li X,Xu J
Sat Apr 01 00:00:00 EDT 2023
RTA dh404 Induces Cell Cycle Arrest, Apoptosis, and Autophagy in Glioblastoma Cells.
International journal of molecular sciences
Tsai TH,Su YF,Tsai CY,Wu CH,Lee KT,Hsu YC
Thu Feb 16 00:00:00 EST 2023
Effect of evernic acid on human breast cancer MCF-7 and MDA-MB-453 cell lines via thioredoxin reductase 1: A molecular approach.
Journal of applied toxicology : JAT
Kalın ŞN,Altay A,Budak H
Tue Aug 01 00:00:00 EDT 2023
Parkin regulates microglial NLRP3 and represses neurodegeneration in Parkinson's disease.
Aging cell
Yan YQ,Zheng R,Liu Y,Ruan Y,Lin ZH,Xue NJ,Chen Y,Zhang BR,Pu JL
Thu Jun 01 00:00:00 EDT 2023
Sirt3 mitigates LPS-induced mitochondrial damage in renal tubular epithelial cells by deacetylating YME1L1.
Cell proliferation
Jian Y,Yang Y,Cheng L,Yang X,Liu H,Li W,Wan Y,Yang D
Wed Feb 01 00:00:00 EST 2023
TWIST1 rescue calcium overload and apoptosis induced by inflammatory microenvironment in S. aureus-induced osteomyelitis.
International immunopharmacology
Wang Y,Dai G,Lin Z,Cheng C,Zhou X,Song M,Chen P,Ma S,Hu Y,Liu G,Yu B
Thu Jun 01 00:00:00 EDT 2023
Suppression of the gut microbiota-bile acid-FGF19 axis in patients with atrial fibrillation.
Cell proliferation
Zuo K,Fang C,Gao Y,Fu Y,Wang H,Li J,Zhong J,Yang X,Xu L
Wed Nov 01 00:00:00 EDT 2023
TREM2 Inhibits Tau Hyperphosphorylation and Neuronal Apoptosis via the PI3K/Akt/GSK-3β Signaling Pathway In vivo and In vitro.
Molecular neurobiology
Peng X,Guo H,Zhang X,Yang Z,Ruganzu JB,Yang Z,Wu X,Bi W,Ji S,Yang W
Mon May 01 00:00:00 EDT 2023
One Stone, Two Birds: A Peptide-Au(I) Infinite Coordination Supermolecule for the Confederate Physical and Biological Radiosensitization in Cancer Radiation Therapy.
Small (Weinheim an der Bergstrasse, Germany)
Wang J,Zhao J,Ma F,Gong L,Lu Y,Xiao W,Tang H,Gao C,Chen Y,Ma J,Gao Z,Yan J,Han S
Wed Mar 01 00:00:00 EST 2023
A novel 2-iminobenzimidazole compound, XYA1353, displays in vitro and in vivo anti-myeloma activity via targeting NF-κB signaling.
Molecular and cellular biochemistry
Gao J,Zhou J,Zhang M,Zhang Y,Zeng Y,Li S,Xu K,Yao R
Fri May 19 00:00:00 EDT 2023
NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer.
Journal of gastrointestinal oncology
Yang H,Pu L,Li R,Zhu R
Sat Apr 29 00:00:00 EDT 2023
DNMT1-mediated lncRNA IFFD controls the follicular development via targeting GLI1 by sponging miR-370.
Cell death and differentiation
Zhou X,He Y,Pan X,Quan H,He B,Li Y,Bai G,Li N,Zhang Z,Zhang H,Li J,Yuan X
Wed Feb 01 00:00:00 EST 2023
Lactoferrin modification of berberine nanoliposomes enhances the neuroprotective effects in a mouse model of Alzheimer's disease.
Neural regeneration research
Wang L,Zhou BQ,Li YH,Jiang QQ,Cong WH,Chen KJ,Wen XM,Wu ZZ
Sun Jan 01 00:00:00 EST 2023
Angiotensin-(1-9) prevents angiotensin II-induced endothelial apoptosis through CNPY2/PERK pathway.
Apoptosis : an international journal on programmed cell death
Guo CL,Liu HM,Li B,Lu ZY
Sat Apr 01 00:00:00 EDT 2023
Antitumor mechanism of kangliu pill on gliomas in mice through PI3K-Akt signaling pathway.
Journal of ethnopharmacology
Chen F,Cui JJ,Jiang DC,Wang HZ,Zhuang W,Feng YN,Lin XL,Xi SY
Wed May 10 00:00:00 EDT 2023
Study on the effect of 5-aminolevulinic acid-mediated photodynamic therapy combined with cisplatin on human ovarian cancer OVCAR-3 cells.
Advances in medical sciences
Lv H,Suo Y,Sun Q,Fan J,Wang Q
Wed Mar 01 00:00:00 EST 2023
S100A6 promotes the development of thyroid cancer and inhibits apoptosis of thyroid cancer cells through the PI3K/AKT/mTOR pathway.
Pathology, research and practice
Chen B,Zheng D,Liu C,Bhandari A,Hirachan S,Shen C,Mainali S,Li H,Jiang W,Xu J,Zhang X,Tang K,Zhang W
Wed Feb 01 00:00:00 EST 2023
OBHS Drives Abnormal Glycometabolis Reprogramming via GLUT1 in Breast Cancer.
International journal of molecular sciences
Wang K,Li Q,Fan Y,Fang P,Zhou H,Huang J
Wed Apr 12 00:00:00 EDT 2023
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
Digestive diseases and sciences
Yang J,Han F,Wu G,Dong Y,Su H,Xu J,Li J
Wed Feb 01 00:00:00 EST 2023
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
Digestive diseases and sciences
Yang J,Han F,Wu G,Dong Y,Su H,Xu J,Li J
Wed Feb 01 00:00:00 EST 2023
Stat3 shRNA delivery with folate receptor-modified multi-functionalized graphene oxide particles for combined infrared radiation and gene therapy in hepatocellular carcinoma.
Anti-cancer drugs
Chen X,Zhang L,Wang X,Xu L,Sun J,Liu Y,Liu X,Kalvakolanu DV,Guo B
Sat Jul 01 00:00:00 EDT 2023
Decreased expression and DNA hypermethylation of syncytin-1 in human villus tissues with unexplained recurrent spontaneous abortion.
Journal of reproductive immunology
Fu Y,Song Y,Zhang J,Wei LP,Sun XR
Wed Feb 01 00:00:00 EST 2023
The p53/miR-29a-3p axis mediates the antifibrotic effect of leonurine on angiotensin II-stimulated rat cardiac fibroblasts.
Experimental cell research
Xi T,Wang R,Pi D,Ouyang J,Yang J
Mon May 01 00:00:00 EDT 2023
Hawthorn fruit extract protect against MC-LR-induced hepatotoxicity by attenuating oxidative stress and apoptosis.
Environmental toxicology
Wang Y,Guo Y,Liu H,Du X,Shi L,Wang W,Zhang S
Thu Jun 01 00:00:00 EDT 2023
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Experimental biology and medicine (Maywood, N.J.)
Wang W,Gu Y,Ni H,Quan Q,Guo L
Thu Jun 01 00:00:00 EDT 2023
Exploring novel biomarkers in dilated cardiomyopathy‑induced heart failure by integrated analysis and in vitro experiments.
Experimental and therapeutic medicine
Zhou L,Peng F,Li J,Gong H
Sat Jul 01 00:00:00 EDT 2023
Prevention of Glutamate-Induced Neurodegeneration by Piceatannol via Mitochondrial Rescue In Vitro and In Vivo.
Molecular nutrition & food research
Koh YC,Chok D,Chang CH,Wei CC,Wu CT,Cheng KC,Nagabhushanam K,Ho CT,Pan MH
Sat Jul 01 00:00:00 EDT 2023
Anti-Postmenopausal osteoporosis effects of Isopsoralen: A bioinformatics-integrated experimental study.
Phytotherapy research : PTR
Li H,Wang C,Jin Y,Cai Y,Yao J,Meng Q,Wu J,Wang H,Sun H,Liu M
Sun Jan 01 00:00:00 EST 2023
Curcumin inhibits proliferation of hepatocellular carcinoma cells by blocking PTPN1 and PTPN11 expression.
Oncology letters
Zhang J,Liu Y,Wang X,Wang Z,Xing E,Li J,Wang D
Sat Jul 01 00:00:00 EDT 2023
Endonuclease G promotes preeclampsia by regulating the Wnt signaling pathway.
Autoimmunity
Yang J,Kou X
Fri Dec 01 00:00:00 EST 2023
SNORD6 promotes cervical cancer progression by accelerating E6-mediated p53 degradation.
Cell death discovery
Li Q,Xie B,Chen X,Lu B,Chen S,Sheng X,Zhao Y
Tue Jun 27 00:00:00 EDT 2023
Lactoferrin attenuated urban particulate matter-induced nephrotoxicity by regulating the CSF2/CENPE axis.
Environmental pollution (Barking, Essex : 1987)
Liu WC,Chiu HW,Chou CL,Chiu YJ,Lee YH
Wed Feb 01 00:00:00 EST 2023
Promotion of colorectal cancer cell death by ezetimibe via mTOR signaling-dependent mitochondrial dysfunction.
Frontiers in pharmacology
Zheng Y,Yang W,Jia Y,Ji J,Wu L,Feng J,Li Y,Cheng Z,Zhang J,Li J,Dai W,Xu X,Wu J,Zhou Y,Guo C
Tue Feb 28 00:00:00 EST 2023
Promotion of colorectal cancer cell death by ezetimibe via mTOR signaling-dependent mitochondrial dysfunction.
Frontiers in pharmacology
Zheng Y,Yang W,Jia Y,Ji J,Wu L,Feng J,Li Y,Cheng Z,Zhang J,Li J,Dai W,Xu X,Wu J,Zhou Y,Guo C
Tue Feb 28 00:00:00 EST 2023
Synthesis of Novel Pentacyclic Triterpenoid Derivatives that Induce Apoptosis in Cancer Cells through a ROS-dependent, Mitochondrial-Mediated Pathway.
Molecular pharmaceutics
Cheng B,Chu X,Liu R,Ma X,Wang M,Zhang J,Jiao P,Gao Q,Ma W,Zhang Y,Zhao C,Zhou D,Xiao S
Mon Jan 02 00:00:00 EST 2023
Destruction of the cellular antioxidant pool contributes to resveratrol-induced senescence and apoptosis in lung cancer.
Phytotherapy research : PTR
Liang C,Yi K,Zhou X,Li X,Zhong C,Cao H,Xie C,Zhu J
Sat Jul 01 00:00:00 EDT 2023
Astaxanthin Alleviates Aflatoxin B1-Induced Oxidative Stress and Apoptosis in IPEC-J2 Cells via the Nrf2 Signaling Pathway.
Toxins
Tian Y,Che H,Yang J,Jin Y,Yu H,Wang C,Fu Y,Li N,Zhang J
Tue Mar 21 00:00:00 EDT 2023
αCGRP deficiency aggravates pulmonary fibrosis by activating the PPARγ signaling pathway.
Genes and immunity
Lv X,Chen Q,Zhang Z,Du K,Huang Y,Li X,Zeng Y
Thu Jun 01 00:00:00 EDT 2023
Gastroprotective effects of ginsenoside Rh4 against ethanol-induced gastric mucosal injury by inhibiting the MAPK/NF-κB signaling pathway.
Food & function
Wu Y,Duan Z,Qu L,Zhang Y,Zhu C,Fan D
Tue Jun 06 00:00:00 EDT 2023
pNaktide mitigates inflammation-induced neuronal damage and behavioral deficits through the oxidative stress pathway.
International immunopharmacology
Zong Q,Pan Y,Liu Y,Wu Z,Huang Z,Zhang Y,Ma K
Wed Mar 01 00:00:00 EST 2023
m6A contributes to a pro-survival state in GC-2 cells by facilitating DNA damage repair: Novel perspectives on the mechanism underlying DEHP genotoxicity in male germ cells.
The Science of the total environment
Fu H,Zhu X,Di Q,Sun J,Jiang Q,Xu Q
Fri Feb 10 00:00:00 EST 2023
Piceatannol and 3'-Hydroxypterostilbene Alleviate Inflammatory Bowel Disease by Maintaining Intestinal Epithelial Integrity and Regulating Gut Microbiota in Mice.
Journal of agricultural and food chemistry
Lin WS,Chueh TL,Nagabhushanam K,Ho CT,Pan MH
Wed Feb 01 00:00:00 EST 2023
Anticancer effect of a pyrrole-imidazole polyamide-triphenylphosphonium conjugate selectively targeting a common mitochondrial DNA cancer risk variant in cervical cancer cells.
International journal of cancer
Yao J,Takenaga K,Koshikawa N,Kida Y,Lin J,Watanabe T,Maru Y,Hippo Y,Yamamoto S,Zhu Y,Nagase H
Wed Mar 01 00:00:00 EST 2023
Network pharmacology integrated with experimental validation revealed potential molecular mechanisms of Camellia nitidissima C. W. Chi in the treatment of lung cancer.
Journal of ethnopharmacology
Zhou A,Zhou C,Wang D,Qian M,Huang L
Thu Oct 05 00:00:00 EDT 2023
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
Heliyon
Wang Y,Yang X,Cao Y,Li X,Xu R,Yan J,Guo Z,Sun S,Sun X,Wu Y
Wed Mar 01 00:00:00 EST 2023
MiR-214-3p may alleviate T-2 toxin-induced chondrocyte apoptosis and matrix degradation by regulating NF-κB signaling pathway in vitro.
Toxicon : official journal of the International Society on Toxinology
Liu L,Zhang H,Jin B,Li H,Zheng X,Li X,Li M,Li M,Nian S,Wang K
Wed Mar 15 00:00:00 EDT 2023
The protective effect of the mitochondrial-derived peptide MOTS-c on LPS-induced septic cardiomyopathy.
Acta biochimica et biophysica Sinica
Wu J,Xiao D,Yu K,Shalamu K,He B,Zhang M
Sat Feb 25 00:00:00 EST 2023
Parecoxib attenuates inflammation injury in septic H9c2 cells by regulating the MAPK signaling pathway.
Experimental and therapeutic medicine
Qian X,Xiong S,Chen Q,Zhang J,Xie J
Sat Apr 01 00:00:00 EDT 2023
Carnosic Acid Attenuates AβOs-Induced Apoptosis and Synaptic Impairment via Regulating NMDAR2B and Its Downstream Cascades in SH-SY5Y Cells.
Molecular neurobiology
Liu WY,Li Y,Li Y,Xu LZ,Jia JP
Sun Jan 01 00:00:00 EST 2023
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Li Y,Zhao R,Xiu Z,Yang X,Zhu Y,Han J,Li S,Li Y,Sun L,Li X,Jin N,Li Y
Tue Jul 25 00:00:00 EDT 2023
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Li Y,Zhao R,Xiu Z,Yang X,Zhu Y,Han J,Li S,Li Y,Sun L,Li X,Jin N,Li Y
Tue Jul 25 00:00:00 EDT 2023
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Li Y,Zhao R,Xiu Z,Yang X,Zhu Y,Han J,Li S,Li Y,Sun L,Li X,Jin N,Li Y
Tue Jul 25 00:00:00 EDT 2023
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Li Y,Zhao R,Xiu Z,Yang X,Zhu Y,Han J,Li S,Li Y,Sun L,Li X,Jin N,Li Y
Tue Jul 25 00:00:00 EDT 2023
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Li Y,Zhao R,Xiu Z,Yang X,Zhu Y,Han J,Li S,Li Y,Sun L,Li X,Jin N,Li Y
Tue Jul 25 00:00:00 EDT 2023
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Li Y,Zhao R,Xiu Z,Yang X,Zhu Y,Han J,Li S,Li Y,Sun L,Li X,Jin N,Li Y
Tue Jul 25 00:00:00 EDT 2023
Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure.
World journal of gastroenterology
Li WY,Yang F,Li X,Wang LW,Wang Y
Tue Feb 28 00:00:00 EST 2023
Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance.
Journal of controlled release : official journal of the Controlled Release Society
Zhang M,Wang L,Jin H,Zhao N,Liu Y,Lan S,Liu S,Zhang H
Thu Jun 01 00:00:00 EDT 2023
Glutathione Might Attenuate Arsenic-Induced Liver Injury by Modulating the Foxa2-XIAP Axis to Reduce Oxidative Stress and Mitochondrial Apoptosis.
Biological trace element research
Zhang H,Jin B,Liu L,Li H,Zheng X,Li M,He R,Wang K
Wed Nov 01 00:00:00 EDT 2023
Periplocin inhibits hepatocellular carcinoma progression and reduces the recruitment of MDSCs through AKT/NF-κB pathway.
Life sciences
Lin JP,Huang MH,Sun ZT,Chen L,Lei YH,Huang YQ,Qi M,Fan SR,Chen SG,Chung CW,Chan MC,Liu JS,Hu M,Chen MF,Ye WC,Chen YY,Deng LJ
Sat Jul 01 00:00:00 EDT 2023
Vitamin B12 alleviates myocardial ischemia/reperfusion injury via the SIRT3/AMPK signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Qin Y,Shi Y,Yu Q,Yang S,Wang Y,Dai X,Li G,Cheng Z
Sat Jul 01 00:00:00 EDT 2023
HAPLN3 inhibits apoptosis and promotes EMT of clear cell renal cell carcinoma via ERK and Bcl-2 signal pathways.
Journal of cancer research and clinical oncology
Ding Y,Xiong S,Chen X,Pan Q,Fan J,Guo J
Sun Jan 01 00:00:00 EST 2023
Chrysomycin A Regulates Proliferation and Apoptosis of Neuroglioma Cells via the Akt/GSK-3β Signaling Pathway In Vivo and In Vitro.
Marine drugs
Liu DN,Liu M,Zhang SS,Shang YF,Zhang WF,Song FH,Zhang HW,Du GH,Wang YH
Sat May 27 00:00:00 EDT 2023
Long non-coding RNA PFI inhibits apoptosis of alveolar epithelial cells to alleviate lung injury via miR-328-3p/Creb1 axis.
Experimental cell research
Li Z,Jin T,Yang R,Guo J,Niu Z,Gao H,Song X,Zhang Q,Ning Z,Ren L,Wang Y,Fan X,Liang H,Li T,He W
Fri Sep 01 00:00:00 EDT 2023
SIRT6 attenuates LPS-induced inflammation and apoptosis of lung epithelial cells in acute lung injury through ACE2/STAT3/PIM1 signaling.
Immunity, inflammation and disease
Yang J,Chen X
Wed Mar 01 00:00:00 EST 2023
Integration of proteomics and network toxicology reveals the mechanism of mercury chloride induced hepatotoxicity, in mice and HepG2 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Cao X,Mao K,Zhang Y,Yang M,Liu H,Wang X,Hao L
Sat Jul 01 00:00:00 EDT 2023
Polyphenol-driven facile assembly of a nanosized acid fibroblast growth factor-containing coacervate accelerates the healing of diabetic wounds.
Acta biomaterialia
Tong MQ,Lu CT,Huang LT,Yang JJ,Yang ST,Chen HB,Xue PP,Luo LZ,Yao Q,Xu HL,Zhao YZ
Wed Feb 01 00:00:00 EST 2023
Erxian decoction alleviates cisplatin-induced premature ovarian failure in rats by reducing oxidation levels in ovarian granulosa cells.
Journal of ethnopharmacology
Liu J,Yang Y,He Y,Feng C,Ou H,Yang J,Chen Y,You F,Shao B,Bao J,Guan X,Chen F,Zhao P
Sat Mar 25 00:00:00 EDT 2023
ESRG is critical to maintain the cell survival and self-renewal/pluripotency of hPSCs by collaborating with MCM2 to suppress p53 pathway.
International journal of biological sciences
Li S,Liu H,Liu W,Shi N,Zhao M,Wanggou S,Luo W,Wang L,Zhu B,Zuo X,Xie W,Zhao C,Zhou Y,Luo L,Gao X,Jiang X,Ren C
Wed Feb 15 00:00:00 EST 2023
The hybrid oncolytic peptide NTP-385 potently inhibits adherent cancer cells by targeting the nucleus.
Acta pharmacologica Sinica
Yin H,Chen XT,Chi QN,Ma YN,Fu XY,Du SS,Qi YK,Wang KW
Sun Jan 01 00:00:00 EST 2023
Astaxanthin Promotes the Survival of Adipose-Derived Stem Cells by Alleviating Oxidative Stress via Activating the Nrf2 Signaling Pathway.
International journal of molecular sciences
Yang CS,Guo XS,Yue YY,Wang Y,Jin XL
Tue Feb 14 00:00:00 EST 2023
The therapeutic mechanism of Yuye decoction on type 2 diabetes mellitus based on network pharmacology and experimental verification.
Journal of ethnopharmacology
Guo F,Yao L,Zhang W,Chen P,Hao R,Huang X,Jiang J,Wu S
Tue May 23 00:00:00 EDT 2023
Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway.
Translational oncology
Ye Z,Xia Y,Li L,Li B,Chen W,Han S,Zhou X,Chen L,Yu W,Ruan Y,Cheng F
Sun Jan 01 00:00:00 EST 2023
Human umbilical cord mesenchymal stem cells conditioned medium exerts anti-tumor effects on KGN cells in a cell density-dependent manner through activation of the Hippo pathway.
Stem cell research & therapy
Wan W,Miao Y,Niu Y,Zhu K,Ma Y,Pan M,Ma B,Wei Q
Mon Mar 20 00:00:00 EDT 2023
BMSC-derived extracellular vesicles promoted osteogenesis via Axin2 inhibition by delivering MiR-16-5p.
International immunopharmacology
Duan J,Li H,Wang C,Yao J,Jin Y,Zhao J,Zhang Y,Liu M,Sun H
Sat Jul 01 00:00:00 EDT 2023
Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination.
Communications biology
Hu J,Jiang W,Zuo J,Shi D,Chen X,Yang X,Zhang W,Ma L,Liu Z,Xing Q
Tue Jan 17 00:00:00 EST 2023
Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway.
Acta pharmacologica Sinica
Liang JP,He YM,Cui YL,Sun YN,He GS,Zhu ZG,Mao XL
Sat Jul 01 00:00:00 EDT 2023
Proteasomal inhibitors induce myeloma cell pyroptosis via the BAX/GSDME pathway.
Acta pharmacologica Sinica
Liang JP,He YM,Cui YL,Sun YN,He GS,Zhu ZG,Mao XL
Sat Jul 01 00:00:00 EDT 2023
C1q/tumor necrosis factor-related protein-9 exerts antioxidant and anti-inflammatory effects on oxygen-glucose deprivation/reoxygenation-stimulated neurons by modulating the Akt-GSK-3β-Nrf2 cascade via AdipoR1.
International immunopharmacology
Wang J,Ren B,Yang Y,Li Y
Mon May 01 00:00:00 EDT 2023
Exploring the synergic mechanism of Ligusticum striatum DC. and borneol in attenuating BMECs injury and maintaining tight junctions against cerebral ischaemia based on the HIF-1α/VEGF signalling pathway.
Journal of ethnopharmacology
Song X,Xing W,Zhang X,Wang X,Ji J,Lu J,Yu B,Ruan M
Mon Jan 30 00:00:00 EST 2023
Non-canonical function of DPP4 promotes cognitive impairment through ERp29-associated mitochondrial calcium overload in diabetes.
iScience
Li J,Hui Y,Xu Z,Tan J,Yin K,Kuang L,Tang Y,Wei J,Zhong Q,Zheng T
Fri Mar 17 00:00:00 EDT 2023
Near-Infrared Phototheranostic Iron Pyrite Nanocrystals Simultaneously Induce Dual Cell Death Pathways via Enhanced Fenton Reactions in Triple-Negative Breast Cancer.
ACS nano
Zhao C,Liu Z,Chang CC,Chen YC,Zhang Q,Zhang XD,Andreou C,Pang J,Liu ZX,Wang DY,Kircher MF,Yang J
Tue Mar 14 00:00:00 EDT 2023
Sodium houttuyfonate exerts its neuroprotection effect by inhibiting the M1 microglia polarization in a TLR4/NF-κB signal pathway.
Brain research
Tang W,Liu L,Yan Y,Xia Y
Thu Jun 15 00:00:00 EDT 2023
Diallyl Trisulfide Suppresses the Renal Cancer Stem-like Cell Properties via Nanog.
Nutrition and cancer
Zhang T,Cao W,Sun H,Yu D,Zhong C
Mon Mar 20 00:00:00 EDT 2023
Sulconazole Induces PANoptosis by Triggering Oxidative Stress and Inhibiting Glycolysis to Increase Radiosensitivity in Esophageal Cancer.
Molecular & cellular proteomics : MCP
Liu LX,Heng JH,Deng DX,Zhao H,Zheng ZY,Liao LD,Lin W,Xu XE,Li EM,Xu LY
Thu Jun 01 00:00:00 EDT 2023
The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis.
Acta biochimica et biophysica Sinica
Li W,Tao C,Mao M,Zhu K
Fri May 26 00:00:00 EDT 2023
Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway.
World journal of gastrointestinal surgery
Zheng Z,Cao F,Ding YX,Lu JD,Fu YQ,Liu L,Guo YL,Liu S,Sun HC,Cui YQ,Li F
Thu Apr 27 00:00:00 EDT 2023
Saturated fatty acid promotes calcification via suppressing SIRT6 expression in vascular smooth muscle cells.
Journal of hypertension
Tao Y,Wu Y,Jiang C,Wang Q,Geng X,Chen L,Zhou S,Wang X,Han M,Du D,Ding B,Li X
Wed Mar 01 00:00:00 EST 2023
Dual-specificity phosphatase 26-dificient neurons are susceptible to oxygen-glucose deprivation/reoxygenation-evoked apoptosis and proinflammatory response by affecting the TAK1-medaited JNK/P38 MAPK pathway.
International immunopharmacology
Zhao H,Lv J,Meng L,Lv J,Li Z
Sat Apr 01 00:00:00 EDT 2023
Aristolocholic acid I promotes renal tubular epithelial fibrosis by upregulating matrix metalloproteinase-9 expression via activating the C3a/C3aR axis of macrophages.
Toxicology letters
Zhang Q,Ye J,Zhang Z,Hu Y,Wang X,Jiang W,Guo X,Chen L,Cheng S,Li J,Zhang L
Mon May 15 00:00:00 EDT 2023
LncRNA-PEAK1 promotes neuronal apoptosis after intracerebral hemorrhage by miR-466i-5p/caspase 8 axis.
Heliyon
Chen JX,Zhi JW,Wang YP,Ning B
Sat Apr 01 00:00:00 EDT 2023
HSPA1A ameliorated spinal cord injury in rats by inhibiting apoptosis to exert neuroprotective effects.
Experimental neurology
He X,Guo X,Deng B,Kang J,Liu W,Zhang G,Wang Y,Yang Y,Kang X
Wed Mar 01 00:00:00 EST 2023
Dihydromyricetin Inhibits Pseudorabies Virus Multiplication In Vitro by Regulating NF-κB Signaling Pathway and Apoptosis.
Veterinary sciences
Zhao X,Chen Y,Zhang W,Zhang H,Hu Y,Yang F,Zhang Y,Song X
Thu Feb 02 00:00:00 EST 2023
The PERK/ATF4/CHOP signaling branch of the unfolded protein response mediates cisplatin-induced ototoxicity in hair cells.
Drug and chemical toxicology
Qu Y,Zong S,Wang Z,Du P,Wen Y,Li H,Wu N,Xiao H
Wed Mar 01 00:00:00 EST 2023
CBL0137 activates ROS/BAX signaling to promote caspase-3/GSDME-dependent pyroptosis in ovarian cancer cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Yang C,Wang ZQ,Zhang ZC,Lou G,Jin WL
Mon May 01 00:00:00 EDT 2023
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
Placenta
Chen M,Chao B,Xu J,Liu Z,Tao Y,He J,Wang J,Yang H,Luo X,Qi H
Fri Mar 03 00:00:00 EST 2023
Lead-induced cardiomyocytes apoptosis by inhibiting gap junction intercellular communication via modulating the PKCα/Cx43 signaling pathway.
Chemico-biological interactions
Wang Q,Ma Y,Li Y,He Z,Feng B
Mon May 01 00:00:00 EDT 2023
Luteolin inhibits triple-negative breast cancer by inducing apoptosis and autophagy through SGK1-FOXO3a-BNIP3 signaling.
Frontiers in pharmacology
Wu L,Lin Y,Gao S,Wang Y,Pan H,Wang Z,Pozzolini M,Yang F,Zhang H,Yang Y,Xiao L,Xu Y
Sat Jul 01 00:00:00 EDT 2023
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Cellular signalling
Wang Y,Ying X,Wang Y,Zou Z,Yuan A,Xiao Z,Geng N,Qiao Z,Li W,Lu X,Pu J
Sat Jul 01 00:00:00 EDT 2023
CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway.
Journal of Cancer
Zhang T,Liu MQ,Xie GS,Wu DM,Luo PW,Liu T,Deng SH,Wang YY,He S,Zhou Y,Zhou J,Xu Y
Thu Jun 08 00:00:00 EDT 2023
CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway.
Journal of Cancer
Zhang T,Liu MQ,Xie GS,Wu DM,Luo PW,Liu T,Deng SH,Wang YY,He S,Zhou Y,Zhou J,Xu Y
Thu Jun 08 00:00:00 EDT 2023
CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway.
Journal of Cancer
Zhang T,Liu MQ,Xie GS,Wu DM,Luo PW,Liu T,Deng SH,Wang YY,He S,Zhou Y,Zhou J,Xu Y
Thu Jun 08 00:00:00 EDT 2023
CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway.
Journal of Cancer
Zhang T,Liu MQ,Xie GS,Wu DM,Luo PW,Liu T,Deng SH,Wang YY,He S,Zhou Y,Zhou J,Xu Y
Thu Jun 08 00:00:00 EDT 2023
Study on Neuroprotective Mechanism of Houshiheisan in Ischemic Stroke Based on Transcriptomics and Experimental Verification.
Evidence-based complementary and alternative medicine : eCAM
Cheng H,Zhang Y,Guo X,Wang X,Wang H,Zhao H,Wang L,Zou H,Zhang Q
Fri Feb 17 00:00:00 EST 2023
Study on Neuroprotective Mechanism of Houshiheisan in Ischemic Stroke Based on Transcriptomics and Experimental Verification.
Evidence-based complementary and alternative medicine : eCAM
Cheng H,Zhang Y,Guo X,Wang X,Wang H,Zhao H,Wang L,Zou H,Zhang Q
Fri Feb 17 00:00:00 EST 2023
Astragalus polysaccharide attenuates bleomycin-induced pulmonary fibrosis by inhibiting TLR4/ NF-κB signaling pathway and regulating gut microbiota.
European journal of pharmacology
Wei Y,Qi M,Liu C,Li L
Wed Apr 05 00:00:00 EDT 2023
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Journal of ethnopharmacology
Zhang X,Wang S,Jin Y,Wang J,Wang R,Yang X,Zhang S,Yan T,Jia Y
Tue May 23 00:00:00 EDT 2023
HCH6-1, an antagonist of formyl peptide receptor-1, exerts anti-neuroinflammatory and neuroprotective effects in cellular and animal models of Parkinson's disease.
Biochemical pharmacology
Wang HL,Cheng YC,Yeh TH,Liu HF,Weng YH,Chen RS,Chen YC,Lu JC,Hwang TL,Wei KC,Liu YC,Wang YT,Hsu CC,Chiu TJ,Chiu CC
Thu Jun 01 00:00:00 EDT 2023
Git1-PGK1 interaction achieves self-protection against spinal cord ischemia-reperfusion injury by modulating Keap1/Nrf2 signaling.
Redox biology
Xu T,Gao P,Huang Y,Wu M,Yi J,Zhou Z,Zhao X,Jiang T,Liu H,Qin T,Yang Z,Wang X,Bao T,Chen J,Zhao S,Yin G
Thu Jun 01 00:00:00 EDT 2023
Triptolide inhibits the progression of Glioblastoma U251 cells via targeting PROX1.
Frontiers in oncology
Yuan C,Liao Y,Liao S,Huang M,Li D,Wu W,Quan Y,Li L,Yu X,Si W
Tue Mar 28 00:00:00 EDT 2023
Endosulfan induced kidney cell injury by modulating ACE2 through up-regulating miR-429 in HK-2 cells.
Toxicology
Zhang B,Liu S,Sun Y,Xu D
Sun Jan 15 00:00:00 EST 2023
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages.
International immunopharmacology
Shen PC,Huang SH,Liu ZM,Lu CC,Chou SH,Tien YC
Sat Jul 01 00:00:00 EDT 2023
A modified Fangji Huangqi decoction ameliorates pulmonary artery hypertension via phosphatidylinositide 3-kinases/protein kinase B-mediated regulation of proliferation and apoptosis of smooth muscle cells in vitro and in vivo.
Journal of ethnopharmacology
Xue Z,Zhou M,Liu Y,Qin H,Li Y,Zhu Y,Yang J
Thu Oct 05 00:00:00 EDT 2023
Thioredoxin1 is a target to attenuate diabetes‑induced RPE cell dysfunction in human ARPE19 cells by alleviating oxidative stress.
Molecular medicine reports
Qi H,Liu T,Liu J,Teng Q,Ma Z,Wang S,Wen S,Zhang C,Ren X,Kong H,Kong L
Sat Jul 01 00:00:00 EDT 2023
A Water-Soluble Hydrogen Sulfide Donor Suppresses the Growth of Hepatocellular Carcinoma via Inhibiting the AKT/GSK-3β/β-Catenin and TGF-β/Smad2/3 Signaling Pathways.
Journal of oncology
Duan SF,Zhang MM,Dong Q,Yang B,Liu W,Zhang X,Yu HL,Zhang SH,Khan NH,Wu DD,Zhang XJ,Cen J
Sat Mar 18 00:00:00 EDT 2023
CircSETD3 mediates acquired resistance to gefitinib in non-small lung cancer cells by FXR1/ECT2 pathway.
The international journal of biochemistry & cell biology
Wen C,Li Y,Huang Y,Wang N,He S,Bao M,Zhou H,Wu L
Sun Jan 01 00:00:00 EST 2023
1,4,5,6,7,8‑Hexahydropyrido[4,3‑d]pyrimidine inhibits HepG2 cell proliferation, migration and invasion, and induces apoptosis through the upregulation of miR‑26b‑5p by targeting CDK8.
Oncology letters
Luo H,Yang Y,Zhou Y,Bai X,Hou Y
Thu Jun 01 00:00:00 EDT 2023
Alpha lipoamide inhibits diabetic kidney fibrosis via improving mitochondrial function and regulating RXRα expression and activation.
Acta pharmacologica Sinica
Zhang HF,Liu HM,Xiang JY,Zhou XC,Wang D,Chen RY,Tan WL,Liang LQ,Liu LL,Shi MJ,Zhang F,Xiao Y,Zhou YX,Zhang T,Tang L,Guo B,Wang YY
Mon May 01 00:00:00 EDT 2023
Apolipoprotein E2 inhibits mitochondrial apoptosis in pancreatic cancer cells through ERK1/2/CREB/BCL-2 signaling.
Hepatobiliary & pancreatic diseases international : HBPD INT
Wang H,Zhou HC,Ren RL,Du SX,Guo ZK,Shen XH
Sat Apr 01 00:00:00 EDT 2023
Apolipoprotein E2 inhibits mitochondrial apoptosis in pancreatic cancer cells through ERK1/2/CREB/BCL-2 signaling.
Hepatobiliary & pancreatic diseases international : HBPD INT
Wang H,Zhou HC,Ren RL,Du SX,Guo ZK,Shen XH
Sat Apr 01 00:00:00 EDT 2023
Fenofibrate attenuates the cytotoxic effect of cisplatin on lung cancer cells by enhancing the antioxidant defense system in vitro.
Oncology letters
Kogami M,Abe S,Nakamura H,Aoshiba K
Sat Jul 01 00:00:00 EDT 2023
Methyl gallate prevents oxidative stress induced apoptosis and ECM degradation in chondrocytes via restoring Sirt3 mediated autophagy and ameliorates osteoarthritis progression.
International immunopharmacology
Li Y,Shen B,Lv C,Zhu X,Naren Q,Xu D,Chen H,Wu F
Sun Jan 01 00:00:00 EST 2023
Immunopotentiation effects of apigenin on NK cell proliferation and killing pancreatic cancer cells.
International journal of immunopathology and pharmacology
Feng YB,Chen L,Chen FX,Yang Y,Chen GH,Zhou ZH,Xu CF
Mon Mar 06 00:00:00 EST 2023
The MyD88 inhibitor, ST2825, induces cell cycle arrest and apoptosis by suppressing the activation of the NF‑κB/AKT1/p21 pathway in pancreatic cancer.
Oncology reports
Lu S,He T,Zhang Y,Zhou B,Zhang Q,Yan S
Tue Aug 01 00:00:00 EDT 2023
Circular forms of dedicator of cytokinesis 1 promotes breast cancer progression by derepressing never in mitosis related kinase 2 via sponging miR-128-3p.
Environmental toxicology
Ni Z,Liu W,Pan G,Mao A,Liu J,Zhang Q,Li J,Liu L,Li H
Sat Jul 01 00:00:00 EDT 2023
Protective mechanism of gold nanoparticles on human neural stem cells injured by β-amyloid protein through miR-21-5p/SOCS6 pathway.
Neurotoxicology
Wang G,Shen X,Song X,Wang N,Wo X,Gao Y
Wed Mar 01 00:00:00 EST 2023
Renal Ischemia-reperfusion Injury Attenuated by Exosomes Extracted From Splenic Ischemic Preconditioning Models.
Transplantation
Liu H,Shen Y
Sat Apr 01 00:00:00 EDT 2023
MicroRNA-22-3p Regulates the Apoptosis of Lens Epithelial Cells Through Targeting KLF6 in Diabetic Cataracts.
Translational vision science & technology
Yin X,Chen L,Shen J,Bi Z,Chen C,Zhao X,Liu S,Li Y
Mon May 01 00:00:00 EDT 2023
Sulforaphane suppresses paraquat-induced oxidative damage in bovine in vitro-matured oocytes through Nrf2 transduction pathway.
Ecotoxicology and environmental safety
Feng Z,Wang T,Sun Y,Chen S,Hao H,Du W,Zou H,Yu D,Zhu H,Pang Y
Sat Apr 01 00:00:00 EDT 2023
Design, synthesis, and SAR study of novel flavone 1,2,4-oxadiazole derivatives with anti-inflammatory activities for the treatment of Parkinson's disease.
European journal of medicinal chemistry
Shen ZB,Meng HW,Meng XS,Lv ZK,Fang MY,Zhang LL,Lv ZL,Li MS,Liu AK,Han JH,Li QS,Duan YJ
Wed Jul 05 00:00:00 EDT 2023
Impairment of rigidity sensing caused by mutant TP53 gain of function in osteosarcoma.
Bone research
Luo M,Huang M,Yang N,Zhu Y,Huang P,Xu Z,Wang W,Cai L
Mon May 29 00:00:00 EDT 2023
An HPK1 inhibitor enhanced the tumour response to anti-PD-1 immunotherapy in non-Hodgkin's lymphoma.
Clinical and experimental medicine
Yang L,Zhao Q,Chen T,Liu W,Qiu X,Chen J,Huang S,Huang R,Dong L
Wed Nov 01 00:00:00 EDT 2023
Roles of TRPV4 in Regulating Circulating Angiogenic Cells to Promote Coronary Microvascular Regeneration.
Journal of cardiovascular translational research
Yang W,Wang H,Guo Q,Xu X,Guo T,Sun L
Sat Apr 01 00:00:00 EDT 2023
Salidroside alleviates acetaminophen-induced hepatotoxicity via Sirt1-mediated activation of Akt/Nrf2 pathway and suppression of NF-κB/NLRP3 inflammasome axis.
Life sciences
Gao Z,Zhan H,Zong W,Sun M,Linghu L,Wang G,Meng F,Chen M
Tue Aug 15 00:00:00 EDT 2023
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Inflammation
Shen Y,Teng L,Qu Y,Huang Y,Peng Y,Tang M,Fu Q
Sat Apr 01 00:00:00 EDT 2023
The organic arsenical-derived thioredoxin and glutathione system inhibitor ACZ2 induces apoptosis and autophagy in gastric cancer via ROS-dependent ER stress.
Biochemical pharmacology
Li Y,She W,Guo T,Huang T,Liu Y,Liu P,Xu X,Wang X,Wang M,Yu C,Liu Y,Wei Y
Wed Feb 01 00:00:00 EST 2023
SIRT3/GLUT4 signaling activation by metformin protect against cisplatin-induced ototoxicity in vitro.
Archives of toxicology
Du P,Liu T,Luo P,Li H,Tang W,Zong S,Xiao H
Sat Apr 01 00:00:00 EDT 2023
High expression of centromere protein N as novel biomarkers for gastric adenocarcinoma.
Cancer reports (Hoboken, N.J.)
Wang X,Zhang K,Fu C,Wu F,Zhang J,Han B,Pan H,Luan L
Sat Apr 01 00:00:00 EDT 2023
Nuciferine improves random skin flap survival via TFEB-mediated activation of autophagy-lysosomal pathway.
International immunopharmacology
Xue K,Zhang G,Zhou Y,Wang K,Yao Z,Chen J,Zhang Y,Li Z,Li Z,Zheng Z,Feng Y,Mao C,Lin C,Xia W
Thu Jun 01 00:00:00 EDT 2023
Penehyclidine Hydrochloride Protects Rat Cardiomyocytes from Ischemia- Reperfusion Injury by Platelet-derived Growth Factor-B.
Combinatorial chemistry & high throughput screening
Lu Y,Zi C,Zhang L,Cui B,Li L,Ma J
Mon Mar 27 00:00:00 EDT 2023
Trimethylamine-N-oxide sensitizes chondrocytes to mechanical loading through the upregulation of Piezo1.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhuang H,Ren X,Zhang Y,Jiang F,Zhou P
Mon May 01 00:00:00 EDT 2023
Exosomes from Adipose-Derived Stem Cells Alleviate Dexamethasone-Induced Bone Loss by Regulating the Nrf2/HO-1 Axis.
Oxidative medicine and cellular longevity
Yao XW,Liu ZY,Ma NF,Jiang WK,Zhou Z,Chen B,Guan WG,Yan JJ,Yang M
Tue Feb 14 00:00:00 EST 2023
HDAC inhibitor HPTA initiates anti-tumor response by CXCL9/10-recruited CXCR3+CD4+T cells against PAHs carcinogenicity.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Chen C,Lim D,Cai Z,Zhang F,Liu G,Dong C,Feng Z
Thu Jun 01 00:00:00 EDT 2023
Empagliflozin-Pretreated Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Attenuated Heart Injury.
Oxidative medicine and cellular longevity
Chi B,Zou A,Mao L,Cai D,Xiao T,Wang Y,Wang Q,Ji Y,Sun L
Wed Mar 01 00:00:00 EST 2023
Ursolic Acid Suppresses Colorectal Cancer by Down-Regulation of Wnt/β-Catenin Signaling Pathway Activity.
Journal of agricultural and food chemistry
Zhao H,Tang S,Tao Q,Ming T,Lei J,Liang Y,Peng Y,Wang M,Liu M,Yang H,Ren S,Xu H
Wed Mar 08 00:00:00 EST 2023
Platelet Lysate Therapy Attenuates Hypoxia Induced Apoptosis in Human Uroepithelial SV-HUC-1 Cells through Regulating the Oxidative Stress and Mitochondrial-Mediated Intrinsic Apoptotic Pathway.
Biomedicines
Wu ZS,Luo HL,Chuang YC,Lee WC,Wang HJ,Chancellor MB
Fri Mar 17 00:00:00 EDT 2023
Sevoflurane Preconditioning Alleviates Posttraumatic Stress Disorder-Induced Apoptosis in the Hippocampus via the EZH2-Regulated Akt/mTOR Axis and Improves Synaptic Plasticity.
Journal of molecular neuroscience : MN
Gu T,Xu C,Meng X,Gao D,Jiang G,Yin A,Liu Q,Zhang L
Mon May 01 00:00:00 EDT 2023
Toosendanin-induced apoptosis of CMT-U27 is mediated through the mitochondrial apoptotic pathway.
Veterinary and comparative oncology
Yang Y,Mei C,Xian H,Zhang X,Li J,Liang ZX,Zhi Y,Ma Y,Wang HJ
Thu Jun 01 00:00:00 EDT 2023
Deficiency of S100A9 Alleviates Sepsis-Induced Acute Liver Injury through Regulating AKT-AMPK-Dependent Mitochondrial Energy Metabolism.
International journal of molecular sciences
Zhang Y,Wu F,Teng F,Guo S,Li H
Fri Jan 20 00:00:00 EST 2023
Lacosamide alleviates bilateral cavernous nerve injury-induced erectile dysfunction in the rat model by ameliorating pathological changes in the corpus cavernosum.
International journal of impotence research
Yao L,Cong R,Zhou X,Zhou X,Ji C,Wei X,Meng X,Song N
Wed Mar 15 00:00:00 EDT 2023
New murine model of alcoholic hepatitis in obesity-induced metabolic-associated fatty liver disease.
Experimental animals
Cheng Y,Lin S,Ren T,Zhang J,Shi Y,Chen Y,Chen Y
Mon Aug 07 00:00:00 EDT 2023
Role of Protein Tyrosine Phosphatase 1B Inhibitor in Early Brain Injury of Subarachnoid Hemorrhage in Mice.
Brain sciences
Zhang ZH,Zhou XM,Zhang X
Thu May 18 00:00:00 EDT 2023
Periostin regulates LPS-induced apoptosis via Nrf2/HO-1 pathway in periodontal ligament fibroblasts.
Oral diseases
Jiang Y,Yang P,Li C,Lu Y,Kou Y,Liu H,Guo J,Li M
Sat Jul 01 00:00:00 EDT 2023
Combination with vorinostat enhances the antitumor activity of cisplatin in castration-resistant prostate cancer by inhibiting DNA damage repair pathway and detoxification of GSH.
The Prostate
Chang T,Lian Z,Ma S,Liang Z,Ma X,Wen X,Wang Y,Liu R
Sat Apr 01 00:00:00 EDT 2023
A Novel Myricetin Derivative with Anti-cancer Properties Induces Cell Cycle Arrest and Apoptosis in A549 Cells.
Biological & pharmaceutical bulletin
Zhou H,Xu L,Shi Y,Gu S,Wu N,Liu F,Huang Y,Qian Z,Xue W,Wang X,Chen F
Thu Jan 05 00:00:00 EST 2023
Apelin-13 Improves Cognitive Impairment and Repairs Hippocampal Neuronal Damage by Activating PGC-1α/PPARγ Signaling.
Neurochemical research
Chen B,Wu J,Hu S,Liu Q,Yang H,You Y
Mon May 01 00:00:00 EDT 2023
Cytotoxic Steroidal Saponins Containing a Rare Fructosyl from the Rhizomes of Paris polyphylla var. latifolia.
International journal of molecular sciences
Li TY,Du Y,Wang MC,Liu K,Liu Y,Cao Y,Wang YY,Chen WW,Qian XY,Qiu PC,Tang HF,Lu YY
Wed Apr 12 00:00:00 EDT 2023
Ndufa4 Regulates the Proliferation and Apoptosis of Neurons via miR-145a-5p/Homer1/Ccnd2.
Molecular neurobiology
Fu F,Chen C,Du K,Li LS,Li R,Lei TY,Deng Q,Wang D,Yu QX,Yang X,Han J,Pan M,Zhen L,Zhang LN,Li J,Li FT,Zhang YL,Jing XY,Li FC,Li DZ,Liao C
Thu Jun 01 00:00:00 EDT 2023
MitoQ Protects Ovarian Organoids against Oxidative Stress during Oogenesis and Folliculogenesis In Vitro.
International journal of molecular sciences
Wang J,Du H,Ma L,Feng M,Li L,Zhao X,Dai Y
Wed Jan 04 00:00:00 EST 2023
Protective Mechanism of Ethyl Gallate against Intestinal Ischemia-Reperfusion Injury in Mice by in Vivo and in Vitro Studies Based on Transcriptomics.
Chemistry & biodiversity
Fan S,Feng X,Li K,Li B,Diao Y
Sun Jan 01 00:00:00 EST 2023
Inhibitory effect and mechanism of hirsuteine on NCI‑H1299 lung cancer cell lines.
Oncology letters
Yun X,Qin H,Du B,Peng Y,Liu Y,Yang B
Mon May 01 00:00:00 EDT 2023
PDK1 regulates the progression of esophageal squamous cell carcinoma through metabolic reprogramming.
Molecular carcinogenesis
Ma Y,Zhang X,Han X,Hao Z,Ji R,Li J,Guo W,Zhang Y,Guan F,Ma S
Thu Jun 01 00:00:00 EDT 2023
PDK1 regulates the progression of esophageal squamous cell carcinoma through metabolic reprogramming.
Molecular carcinogenesis
Ma Y,Zhang X,Han X,Hao Z,Ji R,Li J,Guo W,Zhang Y,Guan F,Ma S
Thu Jun 01 00:00:00 EDT 2023
FSH-inhibited autophagy protects against oxidative stress in goat Sertoli cells through p62-Nrf2 pathway.
Theriogenology
Xi H,Hu Z,Han S,Liu X,Wang L,Hu J
Sun Jan 01 00:00:00 EST 2023
Decreased autophagic activity of detrusor cells is involved in the inflammatory response of interstitial cystitis/bladder pain syndrome.
International urogynecology journal
Zhao J,Lu Q,Yang Z,Sun B,Zhu J,Zhang H,Yang C,Yi S,Dong X
Sat Apr 01 00:00:00 EDT 2023
Decreased autophagic activity of detrusor cells is involved in the inflammatory response of interstitial cystitis/bladder pain syndrome.
International urogynecology journal
Zhao J,Lu Q,Yang Z,Sun B,Zhu J,Zhang H,Yang C,Yi S,Dong X
Sat Apr 01 00:00:00 EDT 2023
Dexpramipexole ameliorates cognitive deficits in sepsis-associated encephalopathy through suppressing mitochondria-mediated pyroptosis and apoptosis.
Neuroreport
Zhang Y,Fu Q,Ruan J,Shi C,Lu W,Wu J,Zhou Z
Wed Mar 01 00:00:00 EST 2023
AKR1B1 Represses Glioma Cell Proliferation through p38 MAPK-Mediated Bcl-2/BAX/Caspase-3 Apoptotic Signaling Pathways.
Current issues in molecular biology
Huang YK,Chang KC,Li CY,Lieu AS,Lin CL
Thu Apr 13 00:00:00 EDT 2023
miR-484 mediates oxidative stress-induced ovarian dysfunction and promotes granulosa cell apoptosis via SESN2 downregulation.
Redox biology
Wang X,Yang J,Li H,Mu H,Zeng L,Cai S,Su P,Li H,Zhang L,Xiang W
Thu Jun 01 00:00:00 EDT 2023
Dioscin reduced chemoresistance for colon cancer and analysis of sensitizing targets.
Biochemical and biophysical research communications
Li R,Qin J,Wang Z,Lv F,Guo J,Zhu H,Huang Y
Sun Jan 01 00:00:00 EST 2023
Hybrids of carbonic anhydrase and cyclooxygenase inhibitors attenuate cardiac hypoxic inflammatory injuries.
European journal of pharmacology
Zhou W,Wang C,Zhang B,Gou S
Wed Jul 05 00:00:00 EDT 2023
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Frontiers in pharmacology
Ma P,Huang N,Tang J,Zhou Z,Xu J,Chen Y,Zhang M,Huang Q,Cheng Y
Sat Mar 04 00:00:00 EST 2023
Glutamine and amino acid metabolism as a prognostic signature and therapeutic target in endometrial cancer.
Cancer medicine
Zhai L,Yang X,Cheng Y,Wang J
Tue Aug 01 00:00:00 EDT 2023
Gsmtx4 Alleviated Osteoarthritis through Piezo1/Calcineurin/NFAT1 Signaling Axis under Excessive Mechanical Strain.
International journal of molecular sciences
Ren X,Zhuang H,Li B,Jiang F,Zhang Y,Zhou P
Thu Feb 16 00:00:00 EST 2023
The pan-cancer analysis of the oncogenic role of FAM72A as a BRCA prognostic biomarker and immunotherapeutic target.
Environmental toxicology
Xu Y,Hirachan S,Shen Y,Huang Q,Bhandari A,Xia E
Mon May 01 00:00:00 EDT 2023
Aloe-emodin ameliorated MI-induced cardiac remodeling in mice via inhibiting TGF-β/SMAD signaling via up-regulating SMAD7.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yu J,Zhao X,Yan X,Li W,Liu Y,Wang J,Wang J,Yang Y,Hao Y,Liang Z,Tao Y,Yuan Y,Du Z
Thu Jun 01 00:00:00 EDT 2023
A multi-bioresponsive self-assembled nano drug delivery system based on hyaluronic acid and geraniol against liver cancer.
Carbohydrate polymers
Duan S,Xia Y,Tian X,Cui J,Zhang X,Yang Q,Zhao T,Lin Y,Zhang F,Zhang X,Cen J
Thu Jun 15 00:00:00 EDT 2023
Shenlian extract decreases mitochondrial autophagy to regulate mitochondrial function in microvascular to alleviate coronary artery no-reflow.
Phytotherapy research : PTR
Li JJ,Wang YJ,Wang CM,Li YJ,Yang Q,Cai WY,Chen Y,Zhu XX
Mon May 01 00:00:00 EDT 2023
TRPM8 promotes hepatocellular carcinoma progression by inducing SNORA55 mediated nuclear-mitochondrial communication.
Cancer gene therapy
Fu J,Liu G,Zhang X,Lei X,Liu Q,Qian K,Tong Q,Qin W,Li Z,Cao Z,Zhang J,Liu C,Wang Z,Liu Z,Liang XM,Yamamoto H,Xu X
Mon May 01 00:00:00 EDT 2023
Electroacupuncture inhibits hippocampal neuronal apoptosis and improves cognitive dysfunction in mice with vascular dementia via the JNK signaling pathway.
Acupuncture in medicine : journal of the British Medical Acupuncture Society
Liu Y,Yan Z,Ren Y,Wang W,Ke Y,Wang Y,Qi R
Sun Oct 01 00:00:00 EDT 2023
Curcumin alleviates ketamine-induced oxidative stress and apoptosis via Nrf2 signaling pathway in rats' cerebral cortex and hippocampus.
Environmental toxicology
Zhang X,Cui Y,Song X,Jin X,Sheng X,Xu X,Li T,Chen H,Gao L
Wed Feb 01 00:00:00 EST 2023
Pien-tze-huang promotes wound healing in streptozotocin-induced diabetes models associated with improving oxidative stress via the Nrf2/ARE pathway.
Frontiers in pharmacology
Liu Y,Mo J,Liang F,Jiang S,Xiong J,Meng X,Mo Z
Thu Feb 02 00:00:00 EST 2023
NSC228155 alleviates septic cardiomyopathy via protecting mitochondria and inhibiting inflammation.
International immunopharmacology
Jiang Y,Li Y,Zhang Y,Hu D,Zhang S,Wang C,Huang S,Zhang A,Jia Z,You R
Wed Mar 01 00:00:00 EST 2023
Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway.
Experimental biology and medicine (Maywood, N.J.)
Li B,Li W,Zheng M,Wang Y,Diao Y,Mou X,Liu J
Wed Feb 01 00:00:00 EST 2023
taVNS Alleviates Sevoflurane-Induced Cognitive Dysfunction in Aged Rats Via Activating Basal Forebrain Cholinergic Neurons.
Neurochemical research
Zhou Q,Zheng Z,Wang X,Li W,Wang L,Yin C,Zhang Q,Wang Q
Thu Jun 01 00:00:00 EDT 2023
Network and experimental pharmacology on mechanism of Si-Wu-tang improving ovarian function in a mouse model of premature ovarian failure induced by cyclophosphamide.
Journal of ethnopharmacology
Liu X,Song Y,Zhou F,Zhang C,Li F,Hu R,Ma W,Song K,Tang Z,Zhang M
Mon Jan 30 00:00:00 EST 2023
Dual regulation of Akt and glutathione caused by isoalantolactone effectively triggers human ovarian cancer cell apoptosis.
Acta biochimica et biophysica Sinica
Xie Z,Xu J,Xiao D,Lei J,Yu J
Sat Feb 25 00:00:00 EST 2023
The protective effect of lncRNA NEAT1/miR-122-5p/Wnt1 axis on hippocampal damage in hepatic ischemic reperfusion young mice.
Cellular signalling
Dong Z,Jia L,Han W,Wang Y,Sheng M,Ren Y,Weng Y,Li H,Yu W
Sat Jul 01 00:00:00 EDT 2023
TFEB attenuates hyperglycemia-induced retinal capillary endothelial cells injury via autophagy regulation.
Cell biology international
Cheng Y,Fan H,Liu K,Liu J,Zou H,You Z
Thu Jun 01 00:00:00 EDT 2023
PTMA binds to HMGB1 to regulate mitochondrial oxidative phosphorylation and thus affect the malignant progression of esophageal squamous cell carcinoma.
Journal of thoracic disease
Chen S,He R,Lin X,Zhang W,Chen H,Xu R,Kang M
Fri Mar 31 00:00:00 EDT 2023
Intermittent fasting alleviates type 1 diabetes-induced cognitive dysfunction by improving the frontal cortical metabolic disorder.
Biochimica et biophysica acta. Molecular basis of disease
Xiong F,Jiang K,Wu Y,Lou C,Ding C,Zhang W,Zhang X,Li C,Zheng H,Gao H
Sun Oct 01 00:00:00 EDT 2023
Perilla frutescens L. alleviates trimethylamine N-oxide-induced apoptosis in the renal tubule by regulating ASK1-JNK phosphorylation.
Phytotherapy research : PTR
Yong C,Huang G,Ge H,Zhu Y,Yang Y,Yu Y,Tian F,Gao K,Zhou E
Sat Apr 01 00:00:00 EDT 2023
Perilla frutescens L. alleviates trimethylamine N-oxide-induced apoptosis in the renal tubule by regulating ASK1-JNK phosphorylation.
Phytotherapy research : PTR
Yong C,Huang G,Ge H,Zhu Y,Yang Y,Yu Y,Tian F,Gao K,Zhou E
Sat Apr 01 00:00:00 EDT 2023
A novel organic arsenic derivative MZ2 remodels metabolism and triggers mtROS-mediated apoptosis in acute myeloid leukemia.
Journal of cancer research and clinical oncology
Chen G,She W,Yu C,Rouzi T,Li X,Ma L,Zhang N,Jiang H,Liu X,Wu J,Wang Q,Shen H,Zhou F
Sat Jul 01 00:00:00 EDT 2023
Potential Effect of Glutamine in the Improvement of Intestinal Stem Cell Proliferation and the Alleviation of Burn-Induced Intestinal Injury via Activating YAP: A Preliminary Study.
Nutrients
Chen X,Zhang P,Zhang Y,Fan S,Wei Y,Yang Z,Wang F,Peng X
Tue Apr 04 00:00:00 EDT 2023
Overexpressing six-transmembrane protein of prostate 2 (STAMP2) alleviates sepsis-induced acute lung injury probably by hindering M1 macrophage polarization via the NF-κB pathway.
Folia histochemica et cytobiologica
Ji L,Shi X,Wang G,Wu H,Hu Z
Thu Mar 30 00:00:00 EDT 2023
METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer.
Cell death & disease
Sun K,Chen L,Li Y,Huang B,Yan Q,Wu C,Lai Q,Fang Y,Cai J,Liu Y,Chen J,Wang X,Zhu Y,Dong S,Tan J,Li A,Liu S,Zhang Y
Tue Feb 21 00:00:00 EST 2023
Adiponectin Attenuates Splenectomy-Induced Cognitive Deficits by Neuroinflammation and Oxidative Stress via TLR4/MyD88/NF-κb Signaling Pathway in Aged Rats.
ACS chemical neuroscience
Zhang Z,Guo L,Yang F,Peng S,Wang D,Lai X,Su B,Xie H
Wed May 17 00:00:00 EDT 2023
Role of Autophagy and Apoptosis in Aluminum Exposure-Induced Liver Injury in Rats.
Biological trace element research
Wei X,Li D,Luo Y,Wu B
Tue Aug 01 00:00:00 EDT 2023
Guf1 overexpression improves pancreatic β cell functions in type 2 diabetes mellitus rats with Roux-en-Y gastric bypass (RYGB) surgery.
Journal of physiology and biochemistry
Li P,Dai S,Gao X,Li W
Tue Aug 01 00:00:00 EDT 2023
Knockdown of KDM5B Leads to DNA Damage and Cell Cycle Arrest in Granulosa Cells via MTF1.
Current issues in molecular biology
Yang Y,Cai Y,Guo J,Dai K,Liu L,Chen Z,Wang F,Deng M
Fri Apr 07 00:00:00 EDT 2023
Dietary Lactobacillus reuteri prevent from inflammation mediated apoptosis of liver via improving intestinal microbiota and bile acid metabolism.
Food chemistry
Lin Z,Wu J,Wang J,Levesque CL,Ma X
Wed Mar 15 00:00:00 EDT 2023
Sulforaphane Suppresses H2O2-Induced Oxidative Stress and Apoptosis via the Activation of AMPK/NFE2L2 Signaling Pathway in Goat Mammary Epithelial Cells.
International journal of molecular sciences
Shao D,Gao Z,Zhao Y,Fan M,Zhao X,Wei Q,Pan M,Ma B
Thu Jan 05 00:00:00 EST 2023
Granulosa cells undergo BPA-induced apoptosis in a miR-21-independent manner.
Experimental cell research
Sabry R,Williams M,LaMarre J,Favetta LA
Thu Jun 01 00:00:00 EDT 2023
Exposure to dithiocarbamate fungicide maneb in vitro and in vivo: Neuronal apoptosis and underlying mechanisms.
Environment international
Liu C,Liu Z,Fang Y,Liao Z,Zhang Z,Yuan X,Yu T,Yang Y,Xiong M,Zhang X,Zhang G,Meng L,Zhang Z
Sun Jan 01 00:00:00 EST 2023
The Wnt/β-catenin pathway regulates inflammation and apoptosis in ventilator-induced lung injury.
Bioscience reports
Chen Z,He S,Lian S,Shen Y,Jiang W,Zhou L,Zhou L,Zhang X
Fri Mar 31 00:00:00 EDT 2023
Neuroplastin 65 deficiency reduces amyloid plaque formation and cognitive deficits in an Alzheimer's disease mouse model.
Frontiers in cellular neuroscience
Wu DD,Cheng J,Zheng YN,Liu YT,Hou SX,Liu LF,Huang L,Yuan QL
Tue May 23 00:00:00 EDT 2023
Experimental study of the effects of absorbable gelatin sponge and non‑absorbable polyvinyl alcohol particle material used in transcatheter arterial embolization on liver tissues.
Experimental and therapeutic medicine
Liu J,Wang S,Xue X,Hu T,Peng X,Huang J,Zhou S
Mon May 01 00:00:00 EDT 2023
Dipeptidyl peptidase 3 is essential for maintaining osteoblastic differentiation under a high-glucose environment by inhibiting apoptosis, oxidative stress and inflammation through the modulation of the Keap1-Nrf2 pathway.
International immunopharmacology
Li X,Yu X,He S,Li J
Sat Jul 01 00:00:00 EDT 2023
Excessive ER-phagy contributes to ochratoxin A-induced apoptosis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Deng H,Chen W,Zhang B,Zhang Y,Han L,Zhang Q,Yao S,Wang H,Shen XL
Thu Jun 01 00:00:00 EDT 2023
Cyclin-dependent kinase subunit2 (CKS2) promotes malignant phenotypes and epithelial-mesenchymal transition-like process in glioma by activating TGFβ/SMAD signaling.
Cancer medicine
Feng F,Zhao Z,Cai X,Heng X,Ma X
Wed Mar 01 00:00:00 EST 2023
Melatonin Increases Proliferation and Decreases Apoptosis of GC-1 spg Cells by Upregulating the Expression of circTec.
Reproductive sciences (Thousand Oaks, Calif.)
Xu C,Yang H,Li C,Wu Z,Ma Y
Sun Jan 01 00:00:00 EST 2023
Dihydroartemisinin elicits immunogenic death through ferroptosis-triggered ER stress and DNA damage for lung cancer immunotherapy.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Han N,Yang ZY,Xie ZX,Xu HZ,Yu TT,Li QR,Li LG,Peng XC,Yang XX,Hu J,Xu X,Chen X,Wang MF,Li TF
Sat Apr 01 00:00:00 EDT 2023
Bta-miR-200b promotes endometrial epithelial cell apoptosis by targeting MYB in cattle.
Theriogenology
Lyu S,Zhai Y,Zhu X,Shi Q,Chen F,Zhang G,Zhang Z,Wang E
Sun Jan 01 00:00:00 EST 2023
Verniciflavanol A, a profisetinidin-type-4-arylflavan-3-ol from toxicodendron vernicifluum protects SH-SY5Y cells against H2O2-Induced oxidative stress.
Phytochemistry
Li M,Zhang Y,Han T,Guan L,Fan D,Wu Q,Liu J,Xu Y,Fan Y
Sun Jan 01 00:00:00 EST 2023
Cathepsin B mediates the lysosomal-mitochondrial apoptosis pathway in arsenic-induced microglial cell injury.
Human & experimental toxicology
Zhang Z,Pi R,Jiang Y,Ahmad M,Luo H,Luo J,Yang J,Sun B
Wed May 10 00:00:00 EDT 2023
Resveratrol Suppresses Bupivacaine-Induced Spinal Neurotoxicity in Rats by Inhibiting Endoplasmic Reticulum Stress via SIRT1 Modulation.
BioMed research international
Luo Y,Zhao Y,Lai J,Wei L,Zhou G,Yu Y,Liu J
Mon Mar 06 00:00:00 EST 2023
Resveratrol Suppresses Bupivacaine-Induced Spinal Neurotoxicity in Rats by Inhibiting Endoplasmic Reticulum Stress via SIRT1 Modulation.
BioMed research international
Luo Y,Zhao Y,Lai J,Wei L,Zhou G,Yu Y,Liu J
Mon Mar 06 00:00:00 EST 2023
Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis.
Journal of orthopaedic translation
Chen Y,Liu Y,Jiang K,Wen Z,Cao X,Wu S
Wed Mar 01 00:00:00 EST 2023
[Overexpression of miR-431-5p impairs mitochondrial function and induces apoptosis in gastric cancer cells via the Bax/Bcl-2/caspase3 pathway].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University
Wu J,Deng Z,Zhu Y,Dou G,Li J,Huang L
Thu Apr 20 00:00:00 EDT 2023
Sulforaphane Suppresses MCF-7 Breast Cancer Cells Growth via miR-19/PTEN Axis to Antagonize the Effect of Butyl Benzyl Phthalate.
Nutrition and cancer
Cao W,Lu X,Zhong C,Wu J
Mon Mar 20 00:00:00 EDT 2023
Myricetin improves apoptosis after ischemic stroke via inhibiting MAPK-ERK pathway.
Molecular biology reports
Zhang L,Zhou T,Ji Q,He L,Lan Y,Ding L,Li L,Wang Z
Wed Mar 01 00:00:00 EST 2023
Alkaloids from Piper longum Exhibit Anti-inflammatory Activity and Synergistic Effects with Chemotherapeutic Agents against Cervical Cancer Cells.
Journal of agricultural and food chemistry
Wan Q,Xu J,Zhu C,Liu X,Tu Y,Lei J,Yu J
Wed Jul 12 00:00:00 EDT 2023
Mechanism Repositioning Based on Integrative Pharmacology: Anti-Inflammatory Effect of Safflower in Myocardial Ischemia-Reperfusion Injury.
International journal of molecular sciences
Zhao F,Jiang H,Zhang T,Chen H,Li W,Li X,Wang P,Xu H
Fri Mar 10 00:00:00 EST 2023
Circular RNA_HIPK3-Targeting miR-93-5p Regulates KLF9 Expression Level to Control Acute Kidney Injury.
Computational and mathematical methods in medicine
Zhengbiao Z,Liang C,Zhi Z,Youmin P
Tue Feb 28 00:00:00 EST 2023
ZBTB7C m6A modification incurred by METTL3 aberration promotes osteosarcoma progression.
Translational research : the journal of laboratory and clinical medicine
An X,Wu W,Yang L,Dong J,Liu B,Guo J,Chen J,Guo B,Cao W,Jiang Q
Fri Sep 01 00:00:00 EDT 2023
Non-Esterified Fatty Acid-Induced Apoptosis in Bovine Granulosa Cells via ROS-Activated PI3K/AKT/FoxO1 Pathway.
Antioxidants (Basel, Switzerland)
Lei Z,Ali I,Yang M,Yang C,Li Y,Li L
Thu Feb 09 00:00:00 EST 2023
MiR-125b-5p/STAT3 Axis Regulates Drug Resistance in Osteosarcoma Cells by Acting on ABC Transporters.
Stem cells international
Yang Y,Chen Y,Liu J,Zhang B,Yang L,Xue J,Zhang Z,Qin L,Bian R
Thu May 11 00:00:00 EDT 2023
Hydrogen sulfide regulates SERCA2a SUMOylation by S-Sulfhydration of SENP1 to ameliorate cardiac systole-diastole function in diabetic cardiomyopathy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Peng S,Wang M,Zhang S,Liu N,Li Q,Kang J,Chen L,Li M,Pang K,Huang J,Lu F,Zhao D,Zhang W
Sat Apr 01 00:00:00 EDT 2023
Flammulina velutipes stem regulates oxidative damage and synthesis of yolk precursors in aging laying hens by regulating the liver-blood-ovary axis.
Poultry science
Wu H,Yuan J,Yin H,Jing B,Sun C,Nguepi Tsopmejio IS,Jin Z,Song H
Sun Jan 01 00:00:00 EST 2023
Allicin ameliorates imiquimod-induced psoriasis-like skin inflammation via disturbing the interaction of keratinocytes with IL-17A.
British journal of pharmacology
Zhang L,Ma X,Shi R,Zhang L,Zhao R,Duan R,Qin Y,Gao S,Li X,Duan J,Li J
Wed Mar 01 00:00:00 EST 2023
Effects of chronic realgar exposure on liver lipidome in mice and identification sensitive lipid biomarker model for realgar-induced liver damage.
Toxicology letters
Huo T,Zhang W,Yang J,Li J,Zhang Y,Guo H,Wu X,Li A,Feng C,Jiang H
Sun Jan 01 00:00:00 EST 2023
Cynanchum komarovii extract for the treatment of rheumatoid arthritis by acting on synovial cells in vitro and in vivo.
Journal of ethnopharmacology
Hao F,Tao L,Liu J,Ma Y,Zhang J,Wang W,Yan W,Wang B,Wang X,Chen X,Ma Y,Fan H,Zhao X,Wang Z,Bai C
Tue Dec 05 00:00:00 EST 2023
The effect of regulating MCU expression on experimental ischemic brain injury.
Experimental neurology
Qin J,Liu L,Liu L,Zhou Z,Zhou Y,Zhang K,Wang B,Lu H,Ran J,Ma T,Zhang Y,Li Z,Liu X
Sat Apr 01 00:00:00 EDT 2023
MiR-29c-5p regulates the function of buffalo granulosa cells to induce follicular atresia by targeting INHBA.
Theriogenology
Cheng J,Wei Y,Zhao Z,Xing Q,Gao Z,Cheng J,Yu C,Pan Y,Yang Y,Shi D,Deng Y
Sat Jul 15 00:00:00 EDT 2023
Fenofibrate Attenuates Renal Tubular Cell Apoptosis by Up-Regulating MCAD in Diabetic Kidney Disease.
Drug design, development and therapy
Tang C,Deng X,Qu J,Miao Y,Tian L,Zhang M,Li X,Sun B,Chen L
Fri May 26 00:00:00 EDT 2023
Identification and evaluation of a novel PARP1 inhibitor for the treatment of triple-negative breast cancer.
Chemico-biological interactions
Gong R,Ma Z,He L,Jiang S,Cao D,Cheng Y
Fri Sep 01 00:00:00 EDT 2023
Antioxidant, Immunostimulatory, and Anticancer Properties of Hydrolyzed Wheat Bran Mediated through Macrophages Stimulation.
International journal of molecular sciences
Tomé-Sánchez I,Martínez-Villaluenga C,Martín-Diana AB,Rico D,Jiménez-Pulido I,Frias J,Dia VP
Tue Apr 18 00:00:00 EDT 2023
A Novel Mitovirus PsMV2 Facilitates the Virulence of Wheat Stripe Rust Fungus.
Viruses
Zhang Y,Guo H,Zhou S,Chen D,Xu G,Kang Z,Zheng L
Sun May 28 00:00:00 EDT 2023
CX3CL1/CX3CR1 axis alleviates inflammation and apoptosis in human nucleus pulpous cells via M2 macrophage polarization.
Experimental and therapeutic medicine
Gao XW,Hu HL,Xie MH,Tang CX,Ou J,Lu ZH
Sat Jul 01 00:00:00 EDT 2023
Daidzein ameliorates doxorubicin-induced cardiac injury by inhibiting autophagy and apoptosis in rats.
Food & function
Wu J,Li K,Liu Y,Feng A,Liu C,Adu-Amankwaah J,Ji M,Ma Y,Hao Y,Bu H,Sun H
Mon Jan 23 00:00:00 EST 2023
High uric acid aggravates apoptosis of lung epithelial cells induced by cigarette smoke extract through downregulating PRDX2 in chronic obstructive pulmonary disease.
International immunopharmacology
Dong Y,Han F,Su Y,Sun B,Zhao W,Pan C
Mon May 01 00:00:00 EDT 2023
Porphin e6 complex loaded with gold nanorod mesoporous silica enhances photodynamic therapy in ovarian cancer cells in vitro.
Lasers in medical science
Sun Q,Suo Y,Lv H,Wang Q,Yin H
Wed May 03 00:00:00 EDT 2023
Magnolol improves Alzheimer's disease-like pathologies and cognitive decline by promoting autophagy through activation of the AMPK/mTOR/ULK1 pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang X,Jia J
Mon May 01 00:00:00 EDT 2023
LEM Domain Containing 1 Acts as a Novel Oncogene and Therapeutic Target for Triple-Negative Breast Cancer.
Cancers
Li X,Jiang S,Jiang T,Sun X,Guan Y,Fan S,Cheng Y
Fri May 26 00:00:00 EDT 2023
Desferoxamine protects against hemophilic arthropathy through the upregulation of HIF-1α-BNIP3 mediated mitophagy.
Life sciences
Lin J,Guo Z,Zheng Z,Hou L,Xu J,Liu Q,Du T,Guo F,Jing X
Sun Jan 01 00:00:00 EST 2023
Natural killer cells strengthen antitumor activity of cisplatin by immunomodulation and ameliorate cisplatin-induced side effects.
International urology and nephrology
Wang Z,Yang Z,Qu C,Li J,Wang X
Tue Aug 01 00:00:00 EDT 2023
miR‑222-3p reduces neuronal cell apoptosis and alleviates spinal cord injury by inhibiting Bbc3 and Bim.
Neuroscience research
Zhang Q,Li G,Kong J,Dai J,Fan Z,Li J
Wed Mar 01 00:00:00 EST 2023
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
The FEBS journal
Kuang H,Sun X,Liu Y,Tang M,Wei Y,Shi Y,Li R,Xiao G,Kang J,Wang F,Peng J,Xu H,Zhou F
Sat Jul 01 00:00:00 EDT 2023
Novel Application of Eupatilin for Effectively Attenuating Cisplatin-Induced Auditory Hair Cell Death via Mitochondrial Apoptosis Pathway.
Oxidative medicine and cellular longevity
Lu X,Deng T,Dong H,Han J,Yu Y,Xiang D,Nie G,Hu B
Tue Mar 08 00:00:00 EST 2022
Ginsenoside Rg3 increases gemcitabine sensitivity of pancreatic adenocarcinoma via reducing ZFP91 mediated TSPYL2 destabilization.
Journal of ginseng research
Pan H,Yang L,Bai H,Luo J,Deng Y
Thu Sep 01 00:00:00 EDT 2022
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
Journal of cellular and molecular medicine
Wang N,Huang R,Yang K,He Y,Gao Y,Dong D
Tue Feb 01 00:00:00 EST 2022
Matairesinol Induces Mitochondrial Dysfunction and Exerts Synergistic Anticancer Effects with 5-Fluorouracil in Pancreatic Cancer Cells.
Marine drugs
Lee W,Song G,Bae H
Mon Jul 25 00:00:00 EDT 2022
Perfluorooctanoic acid induces hepatocellular endoplasmic reticulum stress and mitochondrial-mediated apoptosis in vitro via endoplasmic reticulum-mitochondria communication.
Chemico-biological interactions
Wang Q,Chen W,Zhang B,Gao Z,Zhang Q,Deng H,Han L,Shen XL
Fri Feb 25 00:00:00 EST 2022
Daidzein alleviates doxorubicin-induced heart failure via the SIRT3/FOXO3a signaling pathway.
Food & function
Li H,Zhang M,Wang Y,Gong K,Yan T,Wang D,Meng X,Yang X,Chen Y,Han J,Duan Y,Zhang S
Thu Sep 22 00:00:00 EDT 2022
Daidzein alleviates doxorubicin-induced heart failure via the SIRT3/FOXO3a signaling pathway.
Food & function
Li H,Zhang M,Wang Y,Gong K,Yan T,Wang D,Meng X,Yang X,Chen Y,Han J,Duan Y,Zhang S
Thu Sep 22 00:00:00 EDT 2022
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.
Experimental neurology
Liu MX,Luo L,Fu JH,He JY,Chen MY,He ZJ,Jia J
Tue Mar 01 00:00:00 EST 2022
Oxidative Stress Aggravates Apoptosis of Nucleus Pulposus Cells through m6A Modification of MAT2A Pre-mRNA by METTL16.
Oxidative medicine and cellular longevity
Chen PB,Shi GX,Liu T,Li B,Jiang SD,Zheng XF,Jiang LS
Tue Mar 08 00:00:00 EST 2022
Melatonin attenuates spatial learning and memory dysfunction in developing rats by suppressing isoflurane-induced endoplasmic reticulum stress via the SIRT1/Mfn2/PERK signaling pathway.
Heliyon
Fang X,Han Q,Li S,Luo A
Thu Sep 01 00:00:00 EDT 2022
Taraxasterol Inhibits Tumor Growth by Inducing Apoptosis and Modulating the Tumor Microenvironment in Non-Small Cell Lung Cancer.
Cancers
Lu J,Shuai B,Shou Z,Guo W,Zhou C,Ouyang X,Zhou H,Li J,Cui J,Jiang F,Jin KY,Sarapultsev A,Li F,Zhang G,Luo S,Hu D
Sat Sep 24 00:00:00 EDT 2022
Sophocarpine inhibits tumor progression by antagonizing the PI3K/AKT/mTOR signaling pathway in castration-resistant prostate cancer.
PeerJ
Weng M,Shi C,Han H,Zhu H,Xiao Y,Guo H,Yu Z,Wu C
Wed Jan 18 00:00:00 EST 2023
Cisplatin-induced pyroptosis is mediated via the CAPN1/CAPN2-BAK/BAX-caspase-9-caspase-3-GSDME axis in esophageal cancer.
Chemico-biological interactions
Li RY,Zheng ZY,Li ZM,Heng JH,Zheng YQ,Deng DX,Xu XE,Liao LD,Lin W,Xu HY,Huang HC,Li EM,Xu LY
Fri Jul 01 00:00:00 EDT 2022
Network pharmacology analysis and experimental validation to explore the mechanism of Shenlian extract on myocardial ischemia.
Journal of ethnopharmacology
Li JJ,Wang CM,Wang YJ,Yang Q,Cai WY,Li YJ,Song M,Zang YL,Cui XH,Li Q,Chen Y,Weng XG,Zhu XX
Sun Apr 24 00:00:00 EDT 2022
Glycyrrhiza uralensis Fisch. and its active components mitigate Semen Strychni-induced neurotoxicity through regulating high mobility group box 1 (HMGB1) translocation.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Duan X,Wen J,Zhang M,Wang C,Xiang Y,Wang L,Yu C,Deng G,Yan M,Zhang B,Fang P
Sun May 01 00:00:00 EDT 2022
Periostin promotes nucleus pulposus cells apoptosis by activating the Wnt/β-catenin signaling pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhu D,Wang Z,Zhang G,Ma C,Qiu X,Wang Y,Liu M,Guo X,Chen H,Deng Q,Kang X
Fri Jul 01 00:00:00 EDT 2022
Genistein interferes with antitumor effects of cisplatin in an ovariectomized breast cancer xenograft tumor model.
Toxicology letters
Ma X,Yu X,Min J,Chen X,Liu R,Cui X,Cheng J,Xie M,Diel P,Hu X
Tue Feb 01 00:00:00 EST 2022
Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.
Anatomical record (Hoboken, N.J. : 2007)
Hu JH,Fan P,Zhang LR,Chen CY,Xu J,Huang J,Lu WT,Zhu SJ,Qiu GP,Xu SY,Ran JH,Gan SW
Tue Feb 01 00:00:00 EST 2022
Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H2O2-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway.
Antioxidants (Basel, Switzerland)
Xiong L,Wu H,Zhong T,Luo F,Li Q,Li M,Fan Y
Wed Oct 12 00:00:00 EDT 2022
SKI knockdown suppresses apoptosis and extracellular matrix degradation of nucleus pulposus cells via inhibition of the Wnt/β-catenin pathway and ameliorates disc degeneration.
Apoptosis : an international journal on programmed cell death
Wu ZL,Chen YJ,Zhang GZ,Xie QQ,Wang KP,Yang X,Liu TC,Wang ZQ,Zhao GH,Zhang HH
Tue Feb 01 00:00:00 EST 2022
SKI knockdown suppresses apoptosis and extracellular matrix degradation of nucleus pulposus cells via inhibition of the Wnt/β-catenin pathway and ameliorates disc degeneration.
Apoptosis : an international journal on programmed cell death
Wu ZL,Chen YJ,Zhang GZ,Xie QQ,Wang KP,Yang X,Liu TC,Wang ZQ,Zhao GH,Zhang HH
Tue Feb 01 00:00:00 EST 2022
SKI knockdown suppresses apoptosis and extracellular matrix degradation of nucleus pulposus cells via inhibition of the Wnt/β-catenin pathway and ameliorates disc degeneration.
Apoptosis : an international journal on programmed cell death
Wu ZL,Chen YJ,Zhang GZ,Xie QQ,Wang KP,Yang X,Liu TC,Wang ZQ,Zhao GH,Zhang HH
Tue Feb 01 00:00:00 EST 2022
SKI knockdown suppresses apoptosis and extracellular matrix degradation of nucleus pulposus cells via inhibition of the Wnt/β-catenin pathway and ameliorates disc degeneration.
Apoptosis : an international journal on programmed cell death
Wu ZL,Chen YJ,Zhang GZ,Xie QQ,Wang KP,Yang X,Liu TC,Wang ZQ,Zhao GH,Zhang HH
Tue Feb 01 00:00:00 EST 2022
Resveratrol Induces Apoptosis, Suppresses Migration, and Invasion of Cervical Cancer Cells by Inhibiting the Hedgehog Signaling Pathway.
BioMed research international
Jiang J,Liu Z,Zhou X,Peng F,Wang Z,Li F,Li M
Tue Oct 18 00:00:00 EDT 2022
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Ecotoxicology and environmental safety
Liu F,Wang Y,Chen L,Bello BK,Zhang T,Yang H,Li X,Pan E,Feng H,Dong J
Sat Oct 01 00:00:00 EDT 2022
Number 2 Feibi Recipe Inhibits H2O2-Mediated Oxidative Stress Damage of Alveolar Epithelial Cells by Regulating the Balance of Mitophagy/Apoptosis.
Frontiers in pharmacology
Gu X,Long Q,Wei W,Tong J,Li Z,Zhang Z,Jiao Y
Tue Apr 05 00:00:00 EDT 2022
The Integrated Analysis of Transcriptomics and Metabolomics Unveils the Therapeutical Effect of Asiatic Acid on Alcoholic Hepatitis in Rats.
Inflammation
Chen S,Huang Y,Su H,Zhu W,Wei Y,Long Y,Shi Y,Wei J
Mon Aug 01 00:00:00 EDT 2022
Platelets are highly efficient and efficacious carriers for tumor-targeted nano-drug delivery.
Drug delivery
Li QR,Xu HZ,Xiao RC,Liu Y,Tang JM,Li J,Yu TT,Liu B,Li LG,Wang MF,Han N,Xu YH,Wang C,Komatsu N,Zhao L,Peng XC,Li TF,Chen X
Thu Dec 01 00:00:00 EST 2022
p62 Promotes the Mitochondrial Localization of p53 through Its UBA Domain and Participates in Regulating the Sensitivity of Ovarian Cancer Cells to Cisplatin.
International journal of molecular sciences
Kong Q,Yan X,Cheng M,Jiang X,Xu L,Shen L,Yu H,Sun L
Fri Mar 18 00:00:00 EDT 2022
METTL3 promotes prostatic hyperplasia by regulating PTEN expression in an m6A-YTHDF2-dependent manner.
Cell death & disease
Li J,Yao H,Huang J,Li C,Zhang Y,Xu R,Wang Z,Long Z,Tang J,Wang L
Fri Aug 19 00:00:00 EDT 2022
SGLT2 inhibitor, canagliflozin, ameliorates cardiac inflammation in experimental autoimmune myocarditis.
International immunopharmacology
Long Q,Li L,Yang H,Lu Y,Yang H,Zhu Y,Tang Y,Liu C,Yuan J
Thu Sep 01 00:00:00 EDT 2022
l-Argine regulates the proliferation, apoptosis and endocrine activity by alleviating oxidative stress in sheep endometrial epithelial cells.
Theriogenology
Gao X,Li X,Wang Z,Li K,Liang Y,Yao X,Zhang G,Wang F
Tue Feb 01 00:00:00 EST 2022
SND1 Promotes Radioresistance in Cervical Cancer Cells by Targeting the DNA Damage Response.
Cancer biotherapy & radiopharmaceuticals
Fu X,Duan Z,Lu X,Zhu Y,Ren Y,Zhang W,Sun X,Ge L,Yang J
Thu Mar 10 00:00:00 EST 2022
Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model.
Drug design, development and therapy
Xiao S,Zhou Y,Wang Q,Yang D
Thu Jan 05 00:00:00 EST 2023
Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model.
Drug design, development and therapy
Xiao S,Zhou Y,Wang Q,Yang D
Thu Jan 05 00:00:00 EST 2023
USF1-CHCHD4 axis promotes lung adenocarcinoma progression partially via activating the MYC pathway.
Discover. Oncology
Zhou Y,Zhao Y,Ma W,Zhang L,Jiang Y,Dong W
Thu Dec 08 00:00:00 EST 2022
Inhibition of CDK1 attenuates neuronal apoptosis and autophagy and confers neuroprotection after chronic spinal cord injury in vivo.
Journal of chemical neuroanatomy
Nie BX,Zhao G,Yuan XF,Yu LX,Zhang J,Yuan Y,Liu Y,Hu J,Song E,Zhou YC,Shu J
Sat Jan 01 00:00:00 EST 2022
Integrated strategy of network pharmacology, molecular docking, HPLC-DAD and mice model for exploring active ingredients and pharmacological mechanisms of Penthorum chinense Pursh against alcoholic liver injury.
Journal of ethnopharmacology
Jiang Y,Zhong M,Zhan H,Tao X,Zhang Y,Mao J,Geng Z,Gao B
Tue Nov 15 00:00:00 EST 2022
FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation.
Cellular and molecular life sciences : CMLS
Zhou T,Chen T,Lai B,Zhang W,Luo X,Xia D,Fu W,Xu J
Mon May 02 00:00:00 EDT 2022
Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and intestinal flora.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Hao M,Ding C,Peng X,Chen H,Dong L,Zhang Y,Chen X,Liu W,Luo Y
Sat Oct 01 00:00:00 EDT 2022
Simvastatin Improves Outcomes of Endotoxin-induced Coagulopathy by Regulating Intestinal Microenvironment.
Current medical science
Xu M,Luo LL,Du MY,Tang L,Zhou J,Hu Y,Mei H
Tue Feb 01 00:00:00 EST 2022
GYY4137 ameliorates sepsis-induced cardiomyopathy via NLRP3 pathway.
Biochimica et biophysica acta. Molecular basis of disease
Zhou T,Qian H,Zheng N,Lu Q,Han Y
Thu Dec 01 00:00:00 EST 2022
Platelet-Membrane-Encapsulated Carvedilol with Improved Targeting Ability for Relieving Myocardial Ischemia-Reperfusion Injury.
Membranes
Zhou T,Yang X,Wang T,Xu M,Huang Z,Yu R,Jiang Y,Zhou Y,Shi J
Fri Jun 10 00:00:00 EDT 2022
In situ forming and biocompatible hyaluronic acid hydrogel with reactive oxygen species-scavenging activity to improve traumatic brain injury repair by suppressing oxidative stress and neuroinflammation.
Materials today. Bio
Zhang D,Ren Y,He Y,Chang R,Guo S,Ma S,Guan F,Yao M
Wed Jun 01 00:00:00 EDT 2022
Network pharmacology-based and experimental identification of the effects of Renshen Yangrong decoction on myocardial infarction.
Frontiers in pharmacology
Zhao J,Xu X,Yang X
Fri Nov 18 00:00:00 EST 2022
Andrographolide Inhibits Proliferation and Promotes Apoptosis in Bladder Cancer Cells by Interfering with NF- κ B and PI3K/AKT Signaling In Vitro and In Vivo.
Chinese journal of integrative medicine
Xuan L,Hu JH,Bi R,Liu SQ,Wang CX
Fri Apr 01 00:00:00 EDT 2022
Platelet membrane-camouflaged nanoparticles carry microRNA inhibitor against myocardial ischaemia‒reperfusion injury.
Journal of nanobiotechnology
Wang T,Zhou T,Xu M,Wang S,Wu A,Zhang M,Zhou YL,Shi J
Tue Oct 04 00:00:00 EDT 2022
Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway.
Journal of neuroinflammation
Lu T,Li H,Zhou Y,Wei W,Ding L,Zhan Z,Liu W,Tao J,Xue X
Mon Feb 07 00:00:00 EST 2022
High expression of B4GALT1 is associated with poor prognosis in acute myeloid leukemia.
Frontiers in genetics
Ren Z,Huang X,Lv Q,Lei Y,Shi H,Wang F,Wang M
Tue Jan 03 00:00:00 EST 2023
MiR-7015-3p Targets Nuclear Factor-Kappa-B-Inhibitor Alpha to Aggravate Hypoxia/Reoxygenation Injury in Cardiomyocytes Through the NF-κB Pathway.
International heart journal
Shen X,Tao J,Wang Z,Li G,Zhang Z,Li J,Diliar A
Tue Oct 04 00:00:00 EDT 2022
Acteoside alleviates dextran sulphate sodium‑induced ulcerative colitis via regulation of the HO‑1/HMGB1 signaling pathway.
Molecular medicine reports
Guo W,Wang X,Liu F,Chen S,Wang S,Zhang Q,Yuan L,Du S
Thu Dec 01 00:00:00 EST 2022
TMPRSS12 Functions in Meiosis and Spermiogenesis and Is Required for Male Fertility in Mice.
Frontiers in cell and developmental biology
Zhang J,Zhou X,Wan D,Yu L,Chen X,Yan T,Wu Z,Zheng M,Zhu F,Zhu H
Sat Jul 16 00:00:00 EDT 2022
Design, Synthesis, and Biological Evaluation of N14-Amino Acid-Substituted Tetrandrine Derivatives as Potential Antitumor Agents against Human Colorectal Cancer.
Molecules (Basel, Switzerland)
Wang YC,Zhang RH,Hu SC,Zhang H,Yang D,Zhang WL,Zhao YL,Cui DB,Li YJ,Pan WD,Liao SG,Zhou M
Thu Jun 23 00:00:00 EDT 2022
Legumain affects the PI3K/AKT tumor progression pathway in retinoblastoma.
Experimental eye research
Tang Q,Xu F,Lin J,Zhang C,Liu X,Dong L,Zhao J,Zhu L,Lin T
Tue Nov 01 00:00:00 EDT 2022
Study on the Anti-demyelination Mechanism of Bu-Shen-Yi-Sui Capsule in the Central Nervous System Based on Network Pharmacology and Experimental Verification.
Mediators of inflammation
Zha Z,Liu YJ,Liu SS,Zhang N,Li JL,Qi F,Jin LY,Xue B,Yang T,Fan YP,Zhao H,Wang L
Mon Jul 25 00:00:00 EDT 2022
TMBIM6 promotes diabetic tubular epithelial cell survival and albumin endocytosis by inhibiting the endoplasmic reticulum stress sensor, IRE1α.
Molecular biology reports
Xie H,Shi Y,Zhou Y,Liu H
Sat Oct 01 00:00:00 EDT 2022
Rosmarinic Acid Ameliorates Pulmonary Ischemia/Reperfusion Injury by Activating the PI3K/Akt Signaling Pathway.
Frontiers in pharmacology
Luo W,Tao Y,Chen S,Luo H,Li X,Qu S,Chen K,Zeng C
Sat Jul 16 00:00:00 EDT 2022
Berberine exerts protective effects on cardiac senescence by regulating the Klotho/SIRT1 signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li C,Jiang S,Wang H,Wang Y,Han Y,Jiang J
Fri Jul 01 00:00:00 EDT 2022
Melatonin alleviates arginine vasopressin-induced cardiomyocyte apoptosis via increasing Mst1-Nrf2 pathway activity to reduce oxidative stress.
Biochemical pharmacology
Chen S,Li Y,Fu S,Li Y,Wang C,Sun P,Li H,Tian J,Du GQ
Thu Dec 01 00:00:00 EST 2022
Melatonin improves bisphenol A-induced cell apoptosis, oxidative stress and autophagy impairment via inhibition of the p38 MAPK signaling pathway in FLK-BLV cells.
Environmental toxicology
Song D,Liu Y,Yao Y,Liu F,Tao W,Zhou X,Li R,Zhang X,Li X
Fri Jul 01 00:00:00 EDT 2022
Effect of low energy shock wave on testicular microenvironment homeostasis in rats.
Ecotoxicology and environmental safety
Xing J,Yu G,Xiang Y,Xu H,Liu Z,Bai Z
Mon Aug 01 00:00:00 EDT 2022
Inhibition of 8-oxoguanine DNA glycosylase (OGG1) expression suppresses polycystic ovarian syndrome via the NF-κB signaling pathway.
Reproductive biology
Xia J,Wu S,Wu G,Yang J
Thu Sep 01 00:00:00 EDT 2022
Circular RNA circUSP13 sponges miR-29c to promote differentiation and inhibit apoptosis of goat myoblasts by targeting IGF1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang Z,Fan Y,Deng K,Liang Y,Zhang G,Gao X,El-Samahy MA,Zhang Y,Deng M,Wang F
Sat Jan 01 00:00:00 EST 2022
Protective Effects of Taraxasterol against Deoxynivalenol-Induced Damage to Bovine Mammary Epithelial Cells.
Toxins
Wang J,Zheng K,Jin Y,Fu Y,Wang R,Zhang J
Tue Mar 15 00:00:00 EDT 2022
Lansoprazole-induced osteoporosis via the IP3R- and SOCE-mediated calcium signaling pathways.
Molecular medicine (Cambridge, Mass.)
Cheng Z,Liu Y,Ma M,Sun S,Ma Z,Wang Y,Yu L,Qian X,Sun L,Zhang X,Liu Y,Wang Y
Sat Feb 19 00:00:00 EST 2022
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
Oncogene
Zhang Q,Gao Y,Zhang Y,Jing M,Wang D,Wang Y,Khattak S,Qi H,Cai C,Zhang J,Ngowi EE,Khan NH,Li T,Ji A,Jiang Q,Ji X,Li Y,Wu D
Thu Dec 01 00:00:00 EST 2022
Polyphyllin II induced apoptosis of NSCLC cells by inhibiting autophagy through the mTOR pathway.
Pharmaceutical biology
Jiao Y,Xin M,Xu J,Xiang X,Li X,Jiang J,Jia X
Thu Dec 01 00:00:00 EST 2022
Adipose-Derived Mesenchymal Stem Cells Alleviate Hypertrophic Scar by Inhibiting Bioactivity and Inducing Apoptosis in Hypertrophic Scar Fibroblasts.
Cells
Li S,Yang J,Sun J,Chen M
Mon Dec 12 00:00:00 EST 2022
Study on the new anti-atherosclerosis activity of different Herba patriniae through down-regulating lysophosphatidylcholine of the glycerophospholipid metabolism pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Su D,Liao L,Zeng Q,Liao Z,Liu Y,Jin C,Zhu G,Chen C,Yang M,Ai Z,Song Y
Sat Jan 01 00:00:00 EST 2022
Study on the new anti-atherosclerosis activity of different Herba patriniae through down-regulating lysophosphatidylcholine of the glycerophospholipid metabolism pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Su D,Liao L,Zeng Q,Liao Z,Liu Y,Jin C,Zhu G,Chen C,Yang M,Ai Z,Song Y
Sat Jan 01 00:00:00 EST 2022
Recurrent Hypoglycemia Impaired Vascular Function in Advanced T2DM Rats by Inducing Pyroptosis.
Oxidative medicine and cellular longevity
Luo M,Hu Y,Lv D,Xie L,Yang S,Zuo D,Xue Y,He A
Wed Aug 03 00:00:00 EDT 2022
A pH-Dependent rhodamine fluorophore with antiproliferative activity of bladder cancer in Vitro/Vivo and apoptosis mechanism.
European journal of medicinal chemistry
Lu D,Yang T,Tang N,Li C,Song Y,Wang L,Wong WY,Yin SF,Xing Y,Kambe N,Qiu R
Sun Jun 05 00:00:00 EDT 2022
Gaseous signal molecule SO2 regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Zhao J,Wu Q,Yang T,Nie L,Liu S,Zhou J,Chen J,Jiang Z,Xiao T,Yang J,Chu C
Tue Nov 01 00:00:00 EDT 2022
Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis.
Mediators of inflammation
Yang W,Wang Y,Zhang P,Wang T,Li C,Tong X,Zeng X,Yin Y,Tao K,Li R
Thu Mar 31 00:00:00 EDT 2022
The Novel Competing Endogenous Long Noncoding RNA SM2 Regulates Gonadotropin Secretion in the Hu Sheep Anterior Pituitary by Targeting the Oar-miR-16b/TGF-β/SMAD2 Signaling Pathway.
Cells
Wan Z,Yang H,Chen P,Wang Z,Cai Y,Yao X,Wang F,Zhang Y
Mon Mar 14 00:00:00 EDT 2022
Oleuropein attenuates testicular ischemia-reperfusion by inhibiting apoptosis and inflammation.
Tissue & cell
Xu LZ,He KX,Ning JZ,Cheng F
Sat Oct 01 00:00:00 EDT 2022
Oleuropein attenuates testicular ischemia-reperfusion by inhibiting apoptosis and inflammation.
Tissue & cell
Xu LZ,He KX,Ning JZ,Cheng F
Sat Oct 01 00:00:00 EDT 2022
Silencing lncRNA 93358 Inhibits the Apoptosis of Myocardial Cells in Myocardial Infarction Rats by Inducing the Expression of SLC8A1.
BioMed research international
Cai J,Wang X,Liao W,Zhong Y,Chen L,Zhang Z
Tue Jul 19 00:00:00 EDT 2022
Gluconolactone Alleviates Myocardial Ischemia/Reperfusion Injury and Arrhythmias via Activating PKCε/Extracellular Signal-Regulated Kinase Signaling.
Frontiers in physiology
Qin X,Liu B,Gao F,Hu Y,Chen Z,Xu J,Zhang X
Sat Apr 02 00:00:00 EDT 2022
Aucubin promoted neuron functional recovery by suppressing inflammation and neuronal apoptosis in a spinal cord injury model.
International immunopharmacology
Xiao S,Zhong N,Yang Q,Li A,Tong W,Zhang Y,Yao G,Wang S,Liu J,Liu Z
Sat Oct 01 00:00:00 EDT 2022
The Relationship between Procyanidin Structure and Their Protective Effect in a Parkinson's Disease Model.
Molecules (Basel, Switzerland)
Chen J,Chen Y,Zheng Y,Zhao J,Yu H,Zhu J
Sat Aug 06 00:00:00 EDT 2022
Identification of potential key circular RNAs related to cognitive impairment after chronic constriction injury of the sciatic nerve.
Frontiers in neuroscience
Liu C,Gao R,Tang Y,Chen H,Zhang X,Sun Y,Zhao Q,Lv P,Wang H,Ye-Lehmann S,Liu J,Chen C
Wed Sep 07 00:00:00 EDT 2022
Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD.
Translational psychiatry
Wang L,Chen J,Hu Y,Liao A,Zheng W,Wang X,Lan J,Shen J,Wang S,Yang F,Wang Y,Li Y,Chen D
Tue Mar 22 00:00:00 EDT 2022
TIM-1 promotes proliferation and metastasis, and inhibits apoptosis, in cervical cancer through the PI3K/AKT/p53 pathway.
BMC cancer
Chen L,Qing J,Xiao Y,Huang X,Chi Y,Chen Z
Thu Apr 07 00:00:00 EDT 2022
Macrophages regulate vascular smooth muscle cell function during atherosclerosis progression through IL-1β/STAT3 signaling.
Communications biology
Xue Y,Luo M,Hu X,Li X,Shen J,Zhu W,Huang L,Hu Y,Guo Y,Liu L,Wang L,Luo S
Thu Dec 01 00:00:00 EST 2022
Synthesis and structure-activity relationship study of a potent MHO7 analogue as potential anti-triple negative breast cancer agent.
European journal of medicinal chemistry
Liang JJ,Yu WL,Yang L,Qin KM,Yin YP,Li D,Ni YH,Yan JJ,Zhong YX,Deng ZX,Hong K
Sun Jun 05 00:00:00 EDT 2022
Moderate Aerobic Exercise Regulates Follicular Dysfunction by Initiating Brain-Derived Neurotrophic Factor (BDNF)-Mediated Anti-Apoptotic Signaling Pathways in Polycystic Ovary Syndrome.
Journal of clinical medicine
Zhang Y,Chen D,Wang D,Wang L,Weng Y,Wang H,Wu X,Wang Y
Fri Sep 23 00:00:00 EDT 2022
Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Inflammation
Wan Q,Zhang L,Zhou Q,Han Y,Li Z,Li B
Wed Jun 01 00:00:00 EDT 2022
Protective Effect of Phloretin against Hydrogen Peroxide-Induced Oxidative Damage by Enhancing Autophagic Flux in DF-1 Cells.
Oxidative medicine and cellular longevity
Song D,Liu F,Tao W,Wu X,Bi H,Li X,Shu J,Wang D
Tue Jan 10 00:00:00 EST 2023
HRK inhibits colorectal cancer cells proliferation by suppressing the PI3K/AKT/mTOR pathway.
Frontiers in oncology
Wang H,Chen Y,Yuan Q,Chen L,Dai P,Li X
Tue Jan 03 00:00:00 EST 2023
c-Myc plays a critical role in the antileukemic activity of the Mcl-1-selective inhibitor AZD5991 in acute myeloid leukemia.
Apoptosis : an international journal on programmed cell death
Liu S,Qiao X,Wu S,Gai Y,Su Y,Edwards H,Wang Y,Lin H,Taub JW,Wang G,Ge Y
Thu Dec 01 00:00:00 EST 2022
Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival.
Communications biology
Chen Z,Wu H,Yang J,Li B,Ding J,Cheng S,Bsoul N,Zhang C,Li J,Liu H,Lin D,Gao W
Wed Jun 22 00:00:00 EDT 2022
Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer.
Cell death & disease
Tang X,Liang Y,Sun G,He Q,Hou Z,Jiang X,Gao P,Qu H
Tue Oct 04 00:00:00 EDT 2022
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis.
Life sciences
Chen Q,Han H,Lin F,Yang L,Feng L,Lai X,Wen Z,Yang M,Wang C,Ma Y,Yin T,Lu G,Lin H,Qi J,Yang Y
Thu Dec 01 00:00:00 EST 2022
The preventive and therapeutic effect of repetitive transcranial magnetic stimulation on radiation-induced brain injury in mice.
International journal of radiation biology
Liu LY,Qin TZ,Guo L,Rong-Rong H,Jing YT,Lai PP,Xue YZ,Ding GR
Wed Jul 27 00:00:00 EDT 2022
Therapeutic targeting of ARID1A and PI3K/AKT pathway alterations in cholangiocarcinoma.
PeerJ
Tessiri S,Techasen A,Kongpetch S,Namjan A,Loilome W,Chan-On W,Thanan R,Jusakul A
Fri Jan 06 00:00:00 EST 2023
Co-Targeting ErbB Receptors and the PI3K/AKT Axis in Androgen-Independent Taxane-Sensitive and Taxane-Resistant Human Prostate Cancer Cells.
Cancers
Adediran S,Wang L,Khan MA,Guang W,Fan X,Dan H,Qi J,Jay SM,Carrier F,Hussain A
Fri Sep 23 00:00:00 EDT 2022
Calvatia Lilacina Extracts Exert Anti-Breast-Cancer Bioactivity through the Apoptosis Induction Dependent on Mitochondrial Reactive Oxygen Species and Caspase Activation.
Nutrition and cancer
Zeng Q,Singh R,Ye Y,Cheng S,Fan C,Zeng Q
Wed Apr 13 00:00:00 EDT 2022
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
Aging
Tai H,Cui XZ,He J,Lan ZM,Li SM,Li LB,Yao SC,Jiang XL,Meng XS,Kuang JS
Thu Oct 20 00:00:00 EDT 2022
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
Aging
Tai H,Cui XZ,He J,Lan ZM,Li SM,Li LB,Yao SC,Jiang XL,Meng XS,Kuang JS
Thu Oct 20 00:00:00 EDT 2022
LARS2 Regulates Apoptosis via ROS-Mediated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Ovarian Granulosa Cells.
Oxidative medicine and cellular longevity
Feng S,Wan S,Liu S,Wang W,Tang M,Bai L,Zhu Y
Fri May 20 00:00:00 EDT 2022
Proteomic analysis reveals that Xbp1s promotes hypoxic pulmonary hypertension through the p-JNK MAPK pathway.
Journal of cellular physiology
Jiang H,Niu Y,He Y,Li X,Xu Y,Liu X
Tue Mar 01 00:00:00 EST 2022
Silencing of Angiopoietin-Like Protein 4 (Angptl4) Decreases Inflammation, Extracellular Matrix Degradation, and Apoptosis in Osteoarthritis via the Sirtuin 1/NF-κB Pathway.
Oxidative medicine and cellular longevity
Jia C,Li X,Pan J,Ma H,Wu D,Lu H,Wang W,Zhang X,Yi X
Fri Sep 09 00:00:00 EDT 2022
Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhou X,Wang W,Li Z,Chen L,Wen C,Ruan Q,Xu Z,Liu R,Xu J,Bai Y,Deng J
Sat Jan 01 00:00:00 EST 2022
Leber's hereditary optic neuropathy-associated ND6 14484T > C mutation caused pleiotropic effects on the complex I, RNA homeostasis, apoptosis and mitophagy.
Human molecular genetics
Liang M,Ji Y,Zhang L,Wang X,Hu C,Zhang J,Zhu Y,Mo JQ,Guan MX
Thu Sep 29 00:00:00 EDT 2022
Diterpenoids from the whole plant of Euphorbia wallichii and their protective effects on H2O2-induced BV-2 microglial cells injury.
Bioorganic chemistry
Wang Y,Zhu M,Liang J,Zhang N,Sun D,Li H,Chen L
Tue Nov 01 00:00:00 EDT 2022
Tiao-bu-fei-shen formula promotes downregulation of the caveolin 1-p38 mapk signaling pathway in COPD - Associated tracheobronchomalacia cell model.
Journal of ethnopharmacology
Zhou P,Yu W,Zhang C,Chen K,Tang W,Li X,Liu Z,Xia Q
Fri Jul 15 00:00:00 EDT 2022
Domino hepatocyte transplantation using explanted human livers with metabolic defects attenuates D-GalN/LPS-induced acute liver failure.
Journal of translational medicine
Zhou GP,Li SP,Jiang YZ,Sun J,Tan YL,Zeng ZG,Wei L,Qu W,Sun LY,Zhu ZJ
Thu Oct 20 00:00:00 EDT 2022
HJURP Promotes Malignant Progression and Mediates Sensitivity to Cisplatin and WEE1-inhibitor in Serous Ovarian Cancer.
International journal of biological sciences
Dou Z,Qiu C,Zhang X,Yao S,Zhao C,Wang Z,Chu R,Chen J,Chen Z,Li R,Wang K,Liu P,Liu C,Song K,Kong B
Fri Apr 15 00:00:00 EDT 2022
Comparative and mechanistic study of pharmacodynamic difference in anti-breast cancer activity between water and liquor extracts of Xiaojin Pills.
Journal of ethnopharmacology
Liu H,Cao B,Li C,Han L,Xu H,Lin J,Zhang D,Xu R
Sun Jun 12 00:00:00 EDT 2022
Comparative and mechanistic study of pharmacodynamic difference in anti-breast cancer activity between water and liquor extracts of Xiaojin Pills.
Journal of ethnopharmacology
Liu H,Cao B,Li C,Han L,Xu H,Lin J,Zhang D,Xu R
Sun Jun 12 00:00:00 EDT 2022
Effect of one-time high load exercise on skeletal muscle injury in rats of different genders: oxidative stress and mitochondrial responses.
Acta cirurgica brasileira
Wang Y,Chen M,Gao Y,He K,Yang Z,Li Y,Zhang S,Zhao L
Thu Dec 15 00:00:00 EST 2022
The Selenium Yeast vs Selenium Methionine on Cell Viability, Selenoprotein Profile and Redox Status via JNK/ P38 Pathway in Porcine Mammary Epithelial Cells.
Frontiers in veterinary science
Wu C,Cui C,Zheng X,Wang J,Ma Z,Zhu P,Lin G,Zhang S,Guan W,Chen F
Sat Jul 16 00:00:00 EDT 2022
SERPINA1 is a hub gene associated with intervertebral disc degeneration grade and affects the nucleus pulposus cell phenotype through the ADIRF-AS1/miR-214-3p axis.
Translational research : the journal of laboratory and clinical medicine
Zhong H,Zhou Z,Guo L,Liu FS,Wang X,Li J,Lv GH,Zou MX
Fri Jul 01 00:00:00 EDT 2022
Xanthotoxol suppresses non-small cell lung cancer progression and might improve patients' prognosis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Lin X,Liu J,Zou Y,Tao C,Chen J
Sat Oct 01 00:00:00 EDT 2022
Ki20227 aggravates apoptosis, inflammatory response, and oxidative stress after focal cerebral ischemia injury.
Neural regeneration research
Jiang C,Wang ZN,Kang YC,Chen Y,Lu WX,Ren HJ,Hou BR
Sat Jan 01 00:00:00 EST 2022
Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling Pathway.
Oxidative medicine and cellular longevity
Zhang B,Wan S,Liu H,Qiu Q,Chen H,Chen Z,Wang L,Liu X
Wed Oct 26 00:00:00 EDT 2022
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
Molecular cell
Jiang B,Zhang J,Zhao G,Liu M,Hu J,Lin F,Wang J,Zhao W,Ma H,Zhang C,Wu C,Yao L,Liu Q,Chen X,Cao Y,Zheng Y,Zhang C,Han A,Lin D,Li Q
Thu May 19 00:00:00 EDT 2022
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
Molecular cell
Jiang B,Zhang J,Zhao G,Liu M,Hu J,Lin F,Wang J,Zhao W,Ma H,Zhang C,Wu C,Yao L,Liu Q,Chen X,Cao Y,Zheng Y,Zhang C,Han A,Lin D,Li Q
Thu May 19 00:00:00 EDT 2022
Qi-Tai-Suan, an oleanolic acid derivative, ameliorates ischemic heart failure via suppression of cardiac apoptosis, inflammation and fibrosis.
Chinese journal of natural medicines
Qian M,Feng ZQ,Zheng RN,Hu KW,Sun JZ,Sun HB,Dai L
Wed Jun 01 00:00:00 EDT 2022
Quercetin in Tonglong Qibi decoction ameliorates testosterone-induced benign prostatic hyperplasia in rats by regulating Nrf2 signalling pathways and oxidative stress.
Andrologia
Fu W,Chen S,Zhang Z,Chen Y,You X,Li Q
Sat Oct 01 00:00:00 EDT 2022
Tanshinone IIA regulates glycogen synthase kinase-3β-related signaling pathway and ameliorates memory impairment in APP/PS1 transgenic mice.
European journal of pharmacology
Peng X,Chen L,Wang Z,He Y,Ruganzu JB,Guo H,Zhang X,Ji S,Zheng L,Yang W
Sat Mar 05 00:00:00 EST 2022
Inhibition of TIGAR Increases Exogenous p53 and Cisplatin Combination Sensitivity in Lung Cancer Cells by Regulating Glycolytic Flux.
International journal of molecular sciences
Fu J,Yu S,Zhao X,Zhang C,Shen L,Liu Y,Yu H
Fri Dec 16 00:00:00 EST 2022
Acetyl CoA synthase 2 potentiates ATG5-induced autophagy against neuronal apoptosis after subarachnoid hemorrhage.
Journal of molecular histology
He W,Zhou X,Wu Q,Zhou L,Zhang Z,Zhang R,Deng C,Zhang X
Fri Apr 01 00:00:00 EDT 2022
Preventive effects of the AMPA receptor potentiator LY450108 in an LPS-induced depressive mouse model.
Behavioural brain research
Yao H,Guo W,Suo L,Li G,Wang Y,Chen Y,Sun Y,Ding R
Fri Apr 29 00:00:00 EDT 2022
Sinomenine attenuates alcohol-induced acute liver injury via inhibiting oxidative stress, inflammation and apoptosis in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Fan H,Tu T,Zhang X,Yang Q,Liu G,Zhang T,Bao Y,Lu Y,Dong Z,Dong J,Zhao P
Sat Jan 01 00:00:00 EST 2022
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Clinical and experimental immunology
Wu X,Zhang H,Jiang G,Peng M,Li C,Lu J,Jiang S,Yang X,Jiang Y
Sat Dec 31 00:00:00 EST 2022
Abscopal effects of thoracic X-ray radiation on spermatogenesis in mice.
Frontiers in physiology
Lai PP,Jing YT,Guo L,Qin TZ,Xue YZ,Zhang ZW,Wang X,Miao X,Zhang W,Ding GR
Tue Sep 13 00:00:00 EDT 2022
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
International journal of molecular sciences
Li Y,Zhu Y,Chu B,Liu N,Chen S,Wang J,Zou Y
Thu Apr 28 00:00:00 EDT 2022
Dimethyl Fumarate Ameliorates Doxorubicin-Induced Cardiotoxicity By Activating the Nrf2 Pathway.
Frontiers in pharmacology
Hu X,Li C,Wang Q,Wei Z,Chen T,Wang Y,Li Y
Sat Jul 16 00:00:00 EDT 2022
Baicalin improves the functions of granulosa cells and the ovary in aged mice through the mTOR signaling pathway.
Journal of ovarian research
Fan H,He J,Bai Y,He Q,Zhang T,Zhang J,Yang G,Xu Z,Hu J,Yao G
Thu Mar 17 00:00:00 EDT 2022
Glucolipotoxicity induces endothelial cell dysfunction by activating autophagy and inhibiting autophagic flow.
Diabetes & vascular disease research
Liu Y,Xiang H,Xiong W,Ouyang J,Liu H,Zhao S,Xiao J,Li J,Shu Z,Wang X,Liu H,Zhang J,Fan J,Li Y,Chen S,Lu H
Tue May 17 00:00:00 EDT 2022
Cinacalcet Improves Bone Parameters Through Regulation of Osteoclast Endoplasmic Reticulum Stress, Autophagy, and Apoptotic Pathways in Chronic Kidney Disease-Mineral and Bone Disorder.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Chiu HW,Hou YC,Lu CL,Lu KC,Liu WC,Shyu JF,Chang JF,Zheng CM
Tue Feb 01 00:00:00 EST 2022
Hydrogen gas promotes apoptosis of lung adenocarcinoma A549 cells through X-linked inhibitor of apoptosis and baculoviral inhibitor of apoptosis protein repeat-containing 3.
Journal of cancer research and therapeutics
Zhang Y,Chen G,Yan Z,Wang L,Wang D
Thu Sep 01 00:00:00 EDT 2022
Identification and verification of the role of crucial genes through which methionine restriction inhibits the progression of colon cancer cells.
Oncology letters
Zhou L,Chen Z,Liu C
Mon Aug 01 00:00:00 EDT 2022
Fluid shear stress-induced down-regulation of miR-146a-5p inhibits osteoblast apoptosis via targeting SMAD4.
Physiological research
Liu X,Zhang K,Wang L,Geng B,Liu Z,Yi Q,Xia Y
Fri Dec 16 00:00:00 EST 2022
CD93 promotes acute myeloid leukemia development and is a potential therapeutic target.
Experimental cell research
Jia J,Liu B,Wang D,Wang X,Song L,Ren Y,Guo Z,Ma K,Cui C
Tue Nov 15 00:00:00 EST 2022
Schisandrin B Diet Inhibits Oxidative Stress to Reduce Ferroptosis and Lipid Peroxidation to Prevent Pirarubicin-Induced Hepatotoxicity.
BioMed research international
Shi H,Yan Y,Yang H,Pu P,Tang H
Wed Sep 07 00:00:00 EDT 2022
Inhibition of Mcl-1 Synergistically Enhances the Antileukemic Activity of Gilteritinib and MRX-2843 in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
Cells
Wu S,Edwards H,Wang D,Liu S,Qiao X,Carter J,Wang Y,Taub JW,Wang G,Ge Y
Sat Sep 03 00:00:00 EDT 2022
Chaihujialonggumulitang shows psycho-cardiology therapeutic effect on acute myocardial infarction with comorbid anxiety by the activation of Nrf2/HO-1 pathway and suppression of oxidative stress and apoptosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Shi J,Hou J,Sun Y,Jia Z,Zhou Y,Wang C,Zhao H
Thu Sep 01 00:00:00 EDT 2022
Knockdown of long non-coding RNA plasmacytoma variant translocation 1 relieves ox-LDL-induced endothelial cell injury through regulating microRNA-30c-5p in atherosclerosis.
Bioengineered
Li G,Zong W,Liu L,Wu J,Pang J
Tue Feb 01 00:00:00 EST 2022
Novel chloroquine derivative suppresses melanoma cell growth by DNA damage through increasing ROS levels.
Journal of cellular and molecular medicine
Li J,Long J,Zhang J,Liu N,Yan B,Tang L,Chen X,Peng C
Sun May 01 00:00:00 EDT 2022
Acetyl-11-Keto-Beta Boswellic Acid (AKBA) Protects Lens Epithelial Cells Against H2O2-Induced Oxidative Injury and Attenuates Cataract Progression by Activating Keap1/Nrf2/HO-1 Signaling.
Frontiers in pharmacology
Yang T,Lin X,Li H,Zhou X,Fan F,Yang J,Luo Y,Liu X
Fri Jul 29 00:00:00 EDT 2022
Sestrin2 Overexpression Ameliorates Endoplasmic Reticulum Stress-Induced Apoptosis via Inhibiting mTOR Pathway in HepG2 Cells.
International journal of endocrinology
Hu H,Luo Z,Liu X,Huang L,Lu X,Ding R,Duan C,He Y
Thu Dec 22 00:00:00 EST 2022
MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema.
Oxidative medicine and cellular longevity
Gu Y,Chen J,Huang Q,Zhan Y,Wang T,Wu J,Zhao J,Zeng Z,Lv Y,Xiao C,Xie J
Fri Mar 04 00:00:00 EST 2022
Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD.
Respiratory research
Dai Z,Liu X,Zeng H,Chen Y
Sat Dec 17 00:00:00 EST 2022
Long non-coding RNA lincRNA-erythroid prosurvival (EPS) alleviates cerebral ischemia/reperfusion injury by maintaining high-temperature requirement protein A1 (Htra1) stability through recruiting heterogeneous nuclear ribonucleoprotein L (HNRNPL).
Bioengineered
Guo H,Guo X,Jiang S
Sun May 01 00:00:00 EDT 2022
CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen-glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway.
Metabolic brain disease
Ren X,Yu J,Guo L,Zhang Z
Sat Oct 01 00:00:00 EDT 2022
DJ-1/FGFR-1 Signaling Pathway Contributes to Sorafenib Resistance in Hepatocellular Carcinoma.
Oxidative medicine and cellular longevity
Chen X,Yang G,Guo X,Zhang J,Sun W,Liu D,Wang H,Liu S
Fri Jul 01 00:00:00 EDT 2022
BNIP3 mediates the different adaptive responses of fibroblast-like synovial cells to hypoxia in patients with osteoarthritis and rheumatoid arthritis.
Molecular medicine (Cambridge, Mass.)
Deng R,Wang Y,Bu Y,Wu H
Sat Jun 11 00:00:00 EDT 2022
Label-free Raman spectroscopy characterizes signatures of inflammation and fibrosis in the silicosis.
Biochemical and biophysical research communications
Wang W,Mu M,Zou Y,Li B,Cao H,Hu D,Tao X
Sat May 28 00:00:00 EDT 2022
Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c-Myc pathway.
Food & function
Lu H,Yin H,Qu L,Ma X,Fu R,Fan D
Mon Apr 04 00:00:00 EDT 2022
miR-196a Upregulation Contributes to Gefitinib Resistance through Inhibiting GLTP Expression.
International journal of molecular sciences
Liu BJ,Li FF,Xie YX,Fan CY,Liu WJ,Qiu JG,Jiang BH
Fri Feb 04 00:00:00 EST 2022
Combination of the 6-thioguanine and disulfiram/Cu synergistically inhibits proliferation of triple-negative breast cancer cells by enhancing DNA damage and disrupting DNA damage checkpoint.
Biochimica et biophysica acta. Molecular cell research
Chu M,An X,Zhang D,Li Q,Dai X,Yu H,Li Z
Tue Feb 01 00:00:00 EST 2022
Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation.
Frontiers in medicine
Pei Z,Wu M,Yu H,Long G,Gui Z,Li X,Chen H,Jia Z,Xia W
Tue May 03 00:00:00 EDT 2022
Investigation of the effects of high cervical spinal cord electrical stimulation on improving neurological dysfunction and its potential mechanism in rats with traumatic brain injury.
Neuroreport
Zhao PC,Huang ZS,Xu SN,Deng PC,Qian F,Shi J,Zhang YM
Tue Aug 02 00:00:00 EDT 2022
Insulin and liraglutide attenuate brain pathology in diabetic mice by enhancing the Wnt/β-catenin signaling pathway.
Experimental and therapeutic medicine
Zhao Y,Yu J,Ping F,Xu L,Li W,Zhang H,Li Y
Fri Jul 01 00:00:00 EDT 2022
PCNP is a novel regulator of proliferation, migration, and invasion in human thyroid cancer.
International journal of biological sciences
Chen YG,Liu HX,Hong Y,Dong PZ,Liu SY,Gao YR,Lu D,Li T,Wang DY,Wu DD,Ji XY
Tue Jul 12 00:00:00 EDT 2022
Suppression of EZH2 inhibits TGF-β1-induced EMT in human retinal pigment epithelial cells.
Experimental eye research
Peng Y,Liao K,Tan F,Liang Y,Sun X,Cui Z,Ye B,Chen Z,Tang S,Chen J
Thu Sep 01 00:00:00 EDT 2022
Discovery of precision targeting EZH2 degraders for triple-negative breast cancer.
European journal of medicinal chemistry
Wang C,Chen X,Liu X,Lu D,Li S,Qu L,Yin F,Luo H,Zhang Y,Luo Z,Cui N,Kong L,Wang X
Fri Aug 05 00:00:00 EDT 2022
Recombinant human klotho protects against hydrogen peroxide-mediated injury in human retinal pigment epithelial cells via the PI3K/Akt-Nrf2/HO-1 signaling pathway.
Bioengineered
Wen X,Li S,Zhang Y,Zhu L,Xi X,Zhang S,Li Y
Sun May 01 00:00:00 EDT 2022
Box C/D snoRNA SNORD89 influences the occurrence and development of endometrial cancer through 2'-O-methylation modification of Bim.
Cell death discovery
Bao HJ,Chen X,Liu X,Wu W,Li QH,Xian JY,Zhao Y,Chen S
Tue Jul 05 00:00:00 EDT 2022
Long non-coding RNA MALAT1 modulates myocardial ischemia-reperfusion injury through the PI3K/Akt/eNOS pathway by sponging miRNA-133a-3p to target IGF1R expression.
European journal of pharmacology
Liu XM,Zhang Z,Zhong J,Li N,Wang T,Wang L,Zhang Q
Sat Feb 05 00:00:00 EST 2022
Inhibition of microRNA-29b suppresses oxidative stress and reduces apoptosis in ischemic stroke.
Neural regeneration research
Ma YH,Deng WJ,Luo ZY,Jing J,Pan PW,Yao YB,Fang YB,Teng JF
Tue Feb 01 00:00:00 EST 2022
Lianhuaqingwen alleviates p53-mediated apoptosis in alveolar epithelial cells to prevent LPS-induced ALI.
The Journal of pharmacy and pharmacology
Yang R,Yang H,Li W,Yue F,Chen H,Hao Y,Hu K
Fri Aug 19 00:00:00 EDT 2022
Alleviating effect of quercetin on cadmium-induced oxidative damage and apoptosis by activating the Nrf2-keap1 pathway in BRL-3A cells.
Frontiers in pharmacology
Wang J,Wang K,Ding L,Zhao P,Zhang C,Wang H,Yang Z,Liu Z
Tue Aug 30 00:00:00 EDT 2022
Glucocorticoids induce osteonecrosis of the femoral head in rats via PI3K/AKT/FOXO1 signaling pathway.
PeerJ
Sun F,Zhou JL,Wei SX,Jiang ZW,Peng H
Fri Jan 13 00:00:00 EST 2023
MiR-702-5p ameliorates diabetic encephalopathy in db/db mice by regulating 12/15-LOX.
Experimental neurology
Tu Y,Chen Q,Guo W,Xiang P,Huang H,Fei H,Chen L,Yang Y,Peng Z,Gu C,Tan X,Liu X,Lu Y,Chen R,Wang H,Luo Y,Yang J
Thu Dec 01 00:00:00 EST 2022
Ginsenoside CK induces apoptosis in triple-negative breast cancer cells by targeting glutamine metabolism.
Biochemical pharmacology
Zhang B,Fu R,Duan Z,Shen S,Zhu C,Fan D
Mon Aug 01 00:00:00 EDT 2022
Antitumor activity of Koningic acid in thyroid cancer by inhibiting cellular glycolysis.
Endocrine
Jing C,Li Y,Gao Z,Wang R
Sat Jan 01 00:00:00 EST 2022
SPTBN2 Promotes the Progression of Thyroid Cancer by Accelerating G1/S Transition and Inhibiting Apoptosis.
Disease markers
Zhou X,Lin L,Qi Y,Xu M,Xu Q,Wang Y,Qu J
Tue Aug 16 00:00:00 EDT 2022
Inhibition of thioredoxin reductase 1 by vulpinic acid suppresses the proliferation and migration of human breast carcinoma.
Life sciences
Kalın ŞN,Altay A,Budak H
Thu Dec 01 00:00:00 EST 2022
Mitogen-activating protein kinase kinase kinase kinase-3, inhibited by Astragaloside IV through H3 lysine 4 monomethylation, promotes the progression of diabetic nephropathy by inducing apoptosis.
Bioengineered
Fan Y,Fan H,Li P,Liu Q,Huang L,Zhou Y
Sun May 01 00:00:00 EDT 2022
Small extracellular vesicles of hypoxic endothelial cells regulate the therapeutic potential of adipose-derived mesenchymal stem cells via miR-486-5p/PTEN in a limb ischemia model.
Journal of nanobiotechnology
Shen Z,Wang W,Chen J,Chen B,Tang Y,Hou J,Li J,Liu S,Mei Y,Zhang L,Lu S
Sat Sep 24 00:00:00 EDT 2022
Macamide B Pretreatment Attenuates Neonatal Hypoxic-Ischemic Brain Damage of Mice Induced Apoptosis and Regulates Autophagy via the PI3K/AKT Signaling Pathway.
Molecular neurobiology
Yang X,Wang M,Zhou Q,Bai Y,Liu J,Yang J,Li L,Li G,Luo L
Sun May 01 00:00:00 EDT 2022
Macamide B Pretreatment Attenuates Neonatal Hypoxic-Ischemic Brain Damage of Mice Induced Apoptosis and Regulates Autophagy via the PI3K/AKT Signaling Pathway.
Molecular neurobiology
Yang X,Wang M,Zhou Q,Bai Y,Liu J,Yang J,Li L,Li G,Luo L
Sun May 01 00:00:00 EDT 2022
Exploring the pharmacological mechanisms of icaritin against nasopharyngeal carcinoma via network pharmacology and experimental validation.
Frontiers in pharmacology
Liu M,Hu T,Gou W,Chang H,Li Y,Li Y,Zuo D,Hou W,Jiao S
Fri Feb 17 00:00:00 EST 2023
Hinokiflavone Inhibits Growth of Esophageal Squamous Cancer By Inducing Apoptosis via Regulation of the PI3K/AKT/mTOR Signaling Pathway.
Frontiers in oncology
Guo J,Zhang S,Wang J,Zhang P,Lu T,Zhang L
Fri Jul 22 00:00:00 EDT 2022
Hinokiflavone Inhibits Growth of Esophageal Squamous Cancer By Inducing Apoptosis via Regulation of the PI3K/AKT/mTOR Signaling Pathway.
Frontiers in oncology
Guo J,Zhang S,Wang J,Zhang P,Lu T,Zhang L
Fri Jul 22 00:00:00 EDT 2022
Hinokiflavone Inhibits Growth of Esophageal Squamous Cancer By Inducing Apoptosis via Regulation of the PI3K/AKT/mTOR Signaling Pathway.
Frontiers in oncology
Guo J,Zhang S,Wang J,Zhang P,Lu T,Zhang L
Fri Jul 22 00:00:00 EDT 2022
Hinokiflavone Inhibits Growth of Esophageal Squamous Cancer By Inducing Apoptosis via Regulation of the PI3K/AKT/mTOR Signaling Pathway.
Frontiers in oncology
Guo J,Zhang S,Wang J,Zhang P,Lu T,Zhang L
Fri Jul 22 00:00:00 EDT 2022
Evaluation of the hepatoprotective effect of naringenin loaded nanoparticles against acetaminophen overdose toxicity.
Drug delivery
Lu R,Yu RJ,Yang C,Wang Q,Xuan Y,Wang Z,He Z,Xu Y,Kou L,Zhao YZ,Yao Q,Xu SH
Thu Dec 01 00:00:00 EST 2022
Maizediterpene D from the roots of Zea mays L. alleviates hydrogen peroxide induced oxidative stress and improves cell survival by activation of TrkB/IGF-1R crosstalk pathways.
Fitoterapia
Fan Y,Wu H,Xiong L,Luo F,Li Q,Wang D,Zhong T
Tue Nov 01 00:00:00 EDT 2022
Antitumor Effects of Astaxanthin on Esophageal Squamous Cell Carcinoma by up-Regulation of PPARγ.
Nutrition and cancer
Cui L,Li Z,Xu F,Tian Y,Chen T,Li J,Guo Y,Lyu Q
Tue Apr 26 00:00:00 EDT 2022
NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway.
Aging
Zhao R,Ge Y,Gong Y,Li B,Xiao B,Zuo S
Fri Nov 11 00:00:00 EST 2022
Autophagy Promotes α-Amanitin-Induced Apoptosis of Hepa1-6 Liver Cells.
Chemical research in toxicology
Gu X,Zhang L,Sun W,Liu K,Xu H,Wu P,Gui M,Qu W
Mon Mar 21 00:00:00 EDT 2022
Cancer cells corrupt normal epithelial cells through miR-let-7c-rich small extracellular vesicle-mediated downregulation of p53/PTEN.
International journal of oral science
Liang W,Chen Y,Liu H,Zhao H,Luo T,Tang H,Zhou X,Jiang E,Shao Z,Liu K,Shang Z
Tue Jul 19 00:00:00 EDT 2022
DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism.
Journal of agricultural and food chemistry
Du L,Hao YM,Yang YH,Zheng Y,Wu ZJ,Zhou MQ,Wang BZ,Wang YM,Wu H,Su GH
Wed Mar 09 00:00:00 EST 2022
Hyaluronic acid ameliorates intervertebral disc degeneration via promoting mitophagy activation.
Frontiers in bioengineering and biotechnology
Zhang F,Wang S,Gao M,Li B,He Z,Tang T,Zhu Z,Liu S,Zhou Z
Tue Jan 03 00:00:00 EST 2023
microRNA-338-3p suppresses lipopolysaccharide-induced inflammatory response in HK-2 cells.
BMC molecular and cell biology
Wang J,Li G,Lin M,Lin S,Wu L
Fri Dec 23 00:00:00 EST 2022
PHGDH Inhibitor CBR-5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β-Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib.
Oxidative medicine and cellular longevity
Zhang X,Sun M,Jiao Y,Lin B,Yang Q
Thu Nov 16 00:00:00 EST 2023
Circadian Rhythm Disorders Aggravate Periodontitis by Modulating BMAL1.
International journal of molecular sciences
Liu X,Cao N,Liu X,Deng Y,Xin Y,Fu R,Xin X,Hou Y,Yu W
Mon Dec 26 00:00:00 EST 2022
N-Acetyl-l-tryptophan inhibits CCl4-induced hepatic fibrogenesis via regulating TGF-β1/SMAD and Hippo/YAP1 signal.
Bioorganic chemistry
Ma T,Cheng H,Li T,Chen Y,Cai T,Bai J,Wu Z,Xia X,Liang T,Du Y,Fu W
Thu Sep 01 00:00:00 EDT 2022
Knocking Down Peroxiredoxin 6 Aggravates Cerebral Ischemia-Reperfusion Injury by Enhancing Mitophagy.
Neuroscience
Hong T,Zhou Y,Peng L,Wu X,Li Y,Li Y,Zhao Y
Tue Feb 01 00:00:00 EST 2022
Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability.
Cell communication and signaling : CCS
Yao R,Zhang M,Zhou J,Liu L,Zhang Y,Gao J,Xu K
Thu May 26 00:00:00 EDT 2022
Quercetin Attenuates Quinocetone-Induced Cell Apoptosis In Vitro by Activating the P38/Nrf2/HO-1 Pathway and Inhibiting the ROS/Mitochondrial Apoptotic Pathway.
Antioxidants (Basel, Switzerland)
Dai C,Zhang Q,Shen L,Sharma G,Jiang H,Wang Z,Shen J
Sat Jul 30 00:00:00 EDT 2022
Design, synthesis and biological evaluation of marine phidianidine-inspired derivatives against oxidized ldl-induced endothelial injury by activating Nrf2 anti-oxidation pathway.
Bioorganic chemistry
Xie HX,Wang YH,Zhang JH,Zhang J,Zhong YN,Ge YX,Cheng ZQ,Jiang CS,Meng N
Tue Mar 01 00:00:00 EST 2022
Aerobic Exercise Training Improves Renal Injury in Spontaneously Hypertensive Rats by Increasing Renalase Expression in Medulla.
Frontiers in cardiovascular medicine
Luo M,Cao S,Lv D,He L,He Z,Li L,Li Y,Luo S,Chang Q
Fri Jul 29 00:00:00 EDT 2022
Magnetic Resonance Imaging of Contrast-Induced Acute Renal Injury and Related Pathological Alterations In Vivo.
Analytical cellular pathology (Amsterdam)
Li Y,Shi D,Zhang H,Yao X,Ren K
Mon Apr 04 00:00:00 EDT 2022
Bisphenols A and F, but not S, induce apoptosis in bovine granulosa cells via the intrinsic mitochondrial pathway.
Frontiers in endocrinology
Kourmaeva E,Sabry R,Favetta LA
Mon Nov 21 00:00:00 EST 2022
Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice.
Cell death & disease
Ni L,Xiao J,Zhang D,Shao Z,Huang C,Wang S,Wu Y,Tian N,Sun L,Wu A,Zhou Y,Wang X,Zhang X
Thu Feb 10 00:00:00 EST 2022
Knockdown of long noncoding RNA MIAT attenuates cigarette smoke-induced airway remodeling by downregulating miR-29c-3p-HIF3A axis.
Toxicology letters
Gu W,Wang L,Deng G,Gu X,Tang Z,Li S,Jin W,Yang J,Guo X,Li Q
Tue Mar 01 00:00:00 EST 2022
Induction of Collagen I by CXCL10 in Ovarian Theca-Stroma Cells via the JNK Pathway.
Frontiers in endocrinology
Wang C,Sun Y
Tue Apr 19 00:00:00 EDT 2022
A nanobody-based molecular toolkit for ubiquitin-proteasome system explores the main role of survivin subcellular localization.
Frontiers in bioengineering and biotechnology
Miao H,Liu C,Ouyang H,Zhang P,Liu Y,Zhang C,Deng C,Fu Y,Niu J,Zheng W,You F,Yang Y,Ma X
Tue Feb 07 00:00:00 EST 2023
PP2A promotes apoptosis and facilitates docetaxel sensitivity via the PP2A/p-eIF4B/XIAP signaling pathway in prostate cancer.
Oncology letters
Yin S,Chen Y,Tong H,Li T,Qin Z,Zhu J,He W
Tue Mar 01 00:00:00 EST 2022
Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma.
CNS neuroscience & therapeutics
Yuan F,Zhang S,Sun Q,Ye L,Xu Y,Xu Z,Deng G,Zhang S,Liu B,Chen Q
Wed Jun 01 00:00:00 EDT 2022
Inhibition of Rac1 attenuates radiation-induced lung injury while suppresses lung tumor in mice.
Cell death discovery
An N,Li Z,Yan X,Zhao H,Yang Y,Liu R,Yang Y,Gao F,Li B,Liu H,Yuan H
Fri Jan 14 00:00:00 EST 2022
Myocardium-Targeted Micelle Nanomedicine That Salvages the Heart from Ischemia/Reperfusion Injury.
ACS applied materials & interfaces
Yang L,Peng J,Shi A,Wang X,Li J,Su Y,Yin K,Zhao L,Zhao Y
Wed Aug 31 00:00:00 EDT 2022
FBXL6 depletion restrains clear cell renal cell carcinoma progression.
Translational oncology
Yu Y,Yao W,Wang T,Xue W,Meng Y,Cai L,Jian W,Yu Y,Zhang C
Thu Dec 01 00:00:00 EST 2022
Inhibitory effect of calycosin on breast cancer cell progression through downregulating lncRNA HOTAIR and downstream targets: HuR and IGF2BP1.
Acta biochimica et biophysica Sinica
Li Y,Miao H,Wei W,Tian J,Chen J
Sun Dec 25 00:00:00 EST 2022
The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway.
Cancer gene therapy
Wang F,Luo Y,Zhang L,Younis M,Yuan L
Tue Mar 01 00:00:00 EST 2022
Indole-3-propionic Acid Attenuates HI-Related Blood-Brain Barrier Injury in Neonatal Rats by Modulating the PXR Signaling Pathway.
ACS chemical neuroscience
Zhao Q,Chen T,Ni C,Hu Y,Nan Y,Lin W,Liu Y,Zheng F,Shi X,Lin Z,Zhu J,Lin Z
Wed Oct 05 00:00:00 EDT 2022
Targeted Nanobubbles of PD-L1 mAb Combined with Doxorubicin as a Synergistic Tumor Repressor in Hepatocarcinoma.
International journal of nanomedicine
Chen Y,Luo X,Liu Y,Zou Y,Yang S,Liu C,Zhao Y
Fri Sep 16 00:00:00 EDT 2022
miR-1297 sensitizes glioma cells to temozolomide (TMZ) treatment through targeting adrenomedullin (ADM).
Journal of translational medicine
He Z,Cheng M,Hu J,Liu L,Liu P,Chen L,Cao D,Tang J
Sat Oct 01 00:00:00 EDT 2022
DRAM1 plays a tumor suppressor role in clear cell renal cell carcinoma through modulating Akt signaling.
Acta histochemica
Feng Q,Cheng M,Jin J,Zhang S,Bai Y,Xu J
Fri Apr 01 00:00:00 EDT 2022
Protective effect of nicorandil against myocardial ischemia/reperfusion injury mediated via IL33/ST2 signaling pathway.
Molecular and cellular biochemistry
Zheng Y,Li X,Zhang F,Zhao B,Du W,Sun D,Li G
Fri Jul 01 00:00:00 EDT 2022
Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-β1/Smad Signalling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Ma H,Duan X,Zhang R,Li H,Guo Y,Tian Y,Huang M,Chen G,Wang Z,Li L
Thu Dec 21 00:00:00 EST 2023
Inhibition of IRE1 suppresses the catabolic effect of IL-1β on nucleus pulposus cell and prevents intervertebral disc degeneration in vivo.
Biochemical pharmacology
Kang H,Dong Y,Peng R,Liu H,Guo Q,Song K,Zhu M,Yu K,Wu W,Li F
Tue Mar 01 00:00:00 EST 2022
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy.
Acta pharmaceutica Sinica. B
Sun X,Shu Y,Ye G,Wu C,Xu M,Gao R,Huang D,Zhang J
Tue Feb 01 00:00:00 EST 2022
Dietary phillygenin supplementation ameliorates aflatoxin B1-induced oxidative stress, inflammation, and apoptosis in chicken liver.
Ecotoxicology and environmental safety
Guo J,Yan WR,Tang JK,Jin X,Xue HH,Wang T,Zhang LW,Sun QY,Liang ZX
Sun May 01 00:00:00 EDT 2022
Discovery of a Novel Bloom's Syndrome Protein (BLM) Inhibitor Suppressing Growth and Metastasis of Prostate Cancer.
International journal of molecular sciences
Ma XY,Xu HQ,Zhao JF,Ruan Y,Chen B
Sat Nov 26 00:00:00 EST 2022
Discovery of a Novel Bloom's Syndrome Protein (BLM) Inhibitor Suppressing Growth and Metastasis of Prostate Cancer.
International journal of molecular sciences
Ma XY,Xu HQ,Zhao JF,Ruan Y,Chen B
Sat Nov 26 00:00:00 EST 2022
Discovery of a Novel Bloom's Syndrome Protein (BLM) Inhibitor Suppressing Growth and Metastasis of Prostate Cancer.
International journal of molecular sciences
Ma XY,Xu HQ,Zhao JF,Ruan Y,Chen B
Sat Nov 26 00:00:00 EST 2022
Discovery of a Novel Bloom's Syndrome Protein (BLM) Inhibitor Suppressing Growth and Metastasis of Prostate Cancer.
International journal of molecular sciences
Ma XY,Xu HQ,Zhao JF,Ruan Y,Chen B
Sat Nov 26 00:00:00 EST 2022
Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in SAE mice.
Frontiers in pharmacology
Zhao P,Li X,Yang Q,Lu Y,Wang G,Yang H,Dong J,Zhang H
Thu Feb 02 00:00:00 EST 2023
FGF2 Is Protective Towards Cisplatin-Induced KGN Cell Toxicity by Promoting FTO Expression and Autophagy.
Frontiers in endocrinology
Wang R,Wang L,Wang L,Cui Z,Cheng F,Wang W,Yang X
Wed Jul 06 00:00:00 EDT 2022
Aloe-Emodin Induces Mitochondrial Dysfunction and Pyroptosis by Activation of the Caspase-9/3/Gasdermin E Axis in HeLa Cells.
Frontiers in pharmacology
Li T,Shi L,Liu W,Hu X,Hui Y,Di M,Xue S,Zheng Y,Yao M,Li C,Meng K
Sat Jul 16 00:00:00 EDT 2022
The transcription factor KLF14 attenuates LPS-induced acute lung injury by ameliorating apoptosis of alveolar epithelial cells in mice.
Molecular immunology
Liu L,Yuan Y,Zhou Y,Yao L,Li J,Chen F
Thu Dec 01 00:00:00 EST 2022
Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells.
Frontiers in pharmacology
Xin M,Gao Q,Xiang X,Xu J,Jiao Y,Li X,Zhang X,Jia X
Wed Nov 01 00:00:00 EDT 2023
CORM-3 Attenuates Oxidative Stress-Induced Bone Loss via the Nrf2/HO-1 Pathway.
Oxidative medicine and cellular longevity
Jin C,Lin BH,Zheng G,Tan K,Liu GY,Yao Z,Xie J,Chen WK,Chen L,Xu TH,Huang CB,Wu ZY,Yang L
Tue Aug 30 00:00:00 EDT 2022
DsbA-L interacts with VDAC1 in mitochondrion-mediated tubular cell apoptosis and contributes to the progression of acute kidney disease.
EBioMedicine
Li X,Pan J,Li H,Li G,Liu B,Tang X,Liu X,He Z,Peng Z,Zhang H,Wang L,Li Y,Xiang X,Chai X,Yuan Y,Zheng P,Zhang D
Tue Feb 01 00:00:00 EST 2022
Resveratrol inhibits the progression of premature senescence partially by regulating v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) and sirtuin 1 (SIRT1).
Renal failure
He S,Zhou M,Zheng H,Wang Y,Wu S,Gao Y,Chen J
Thu Dec 01 00:00:00 EST 2022
Synthetic mRNA-based gene therapy for glioblastoma: TRAIL-mRNA synergistically enhances PTEN-mRNA-based therapy.
Molecular therapy oncolytics
Tang X,Peng H,Xu P,Zhang L,Fu R,Tu H,Guo X,Huang K,Lu J,Chen H,Dong Z,Dai L,Luo J,Chen Q
Thu Mar 17 00:00:00 EDT 2022
Ellagic Acid Alleviates Mice Intestinal Ischemia-Reperfusion Injury: A Study Based on Transcriptomics Combined with Functional Experiments.
Chemistry & biodiversity
Fan S,Xu Y,Li K,Li B,Diao Y
Tue Nov 01 00:00:00 EDT 2022
Oxidative Stress-Induced TRPV2 Expression Increase Is Involved in Diabetic Cataracts and Apoptosis of Lens Epithelial Cells in a High-Glucose Environment.
Cells
Chen L,Chen Y,Ding W,Zhan T,Zhu J,Zhang L,Wang H,Shen B,Wang Y
Sat Apr 02 00:00:00 EDT 2022
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
Materials today. Bio
Li J,Luo G,Zhang C,Long S,Guo L,Yang G,Wang F,Zhang L,Shi L,Fu Y,Zhang Y
Tue Mar 01 00:00:00 EST 2022
Arsenic causes mitochondrial biogenesis obstacles by inhibiting the AMPK/PGC-1α signaling pathway and also induces apoptosis and dysregulated mitophagy in the duck liver.
Ecotoxicology and environmental safety
Zhong G,Hu T,Tang L,Li T,Wu S,Duan X,Pan J,Zhang H,Tang Z,Feng X,Hu L
Sat Jan 15 00:00:00 EST 2022
Knockdown of Annexin A2 Enhances Radiosensitivity by Increasing G2/M-Phase Arrest, Apoptosis and Activating the p38 MAPK-HSP27 Pathway in Nasopharyngeal Carcinoma.
Frontiers in oncology
He H,Lin K,Zou C,Pan J,Fu W,Zhou Y,Lin H,Chen C,Su Y
Tue Apr 05 00:00:00 EDT 2022
Structural Variability of Lipoarabinomannan Modulates Innate Immune Responses within Infected Alveolar Epithelial Cells.
Cells
Liu H,Gui X,Chen S,Fu W,Li X,Xiao T,Hou J,Jiang T
Fri Jan 21 00:00:00 EST 2022
Protective Effects of Vitamin C against Neomycin-Induced Apoptosis in HEI-OC1 Auditory Cell.
Neural plasticity
Gong L,Chen B,Chen J,Li Y
Tue May 24 00:00:00 EDT 2022
Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells.
Reproductive toxicology (Elmsford, N.Y.)
Gu X,Liu H,Luo W,Wang X,Wang H,Li L
Thu Dec 01 00:00:00 EST 2022
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
Oxidative medicine and cellular longevity
Wang P,Zhang S,Liu W,Chen S,Lv X,Hu B,Shao Z
Mon Apr 25 00:00:00 EDT 2022
Propofol Upregulates MicroRNA-30b to Inhibit Excessive Autophagy and Apoptosis and Attenuates Ischemia/Reperfusion Injury In Vitro and in Patients.
Oxidative medicine and cellular longevity
Lu Z,Shen J,Chen X,Ruan Z,Cai W,Cai S,Li M,Yang Y,Mo J,Mo G,Lu Y,Tang J,Zhang L
Tue Apr 12 00:00:00 EDT 2022
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhong Y,Luo R,Liu Q,Zhu J,Lei M,Liang X,Wang X,Peng X
Sat Jan 01 00:00:00 EST 2022
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhong Y,Luo R,Liu Q,Zhu J,Lei M,Liang X,Wang X,Peng X
Sat Jan 01 00:00:00 EST 2022
Deduction of CDC42EP3 suppress development and progression of osteosarcoma.
Experimental cell research
Xu P,Li X,Tang C,Wang T,Xu J
Tue Mar 01 00:00:00 EST 2022
Maslinic Acid Inhibits Myocardial Ischemia-Reperfusion Injury-Induced Apoptosis and Necroptosis via Promoting Autophagic Flux.
DNA and cell biology
Li L,Lin L,Lei S,Shi S,Chen C,Xia Z
Sun May 01 00:00:00 EDT 2022
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Frontiers in pharmacology
Chen Y,Li T,Tan P,Shi H,Cheng Y,Cai T,Bai J,Du Y,Fu W
Sat Jul 16 00:00:00 EDT 2022
Dl-3-n-Butylphthalide Improves Neuroinflammation in Mice with Repeated Cerebral Ischemia-Reperfusion Injury through the Nrf2-Mediated Antioxidant Response and TLR4/MyD88/NF-κB Signaling Pathway.
Oxidative medicine and cellular longevity
Gao Y,Hu M,Niu X,Li M,Xu L,Xiao Y,Zhang J,Wang H,Li L,Chu B,Lv P
Tue Dec 13 00:00:00 EST 2022
Effect of rapamycin treatment on oocyte in vitro maturation and embryonic development after parthenogenesis in yaks.
Theriogenology
Zhang T,Wang L,Pan Y,He H,Wang J,Zhao T,Ding T,Wang Y,Zhao L,Han X,Fan J,Xu G,Cui Y,Yu S
Tue Nov 01 00:00:00 EDT 2022
HA-ADT suppresses esophageal squamous cell carcinoma progression via apoptosis promotion and autophagy inhibition.
Experimental cell research
Duan SF,Zhang MM,Zhang X,Liu W,Zhang SH,Yang B,Dong Q,Han JG,Yu HL,Li T,Ji XY,Wu DD,Zhang XJ
Tue Nov 01 00:00:00 EDT 2022
Furfural Produces Dose-Dependent Attenuating Effects on Ethanol-Induced Toxicity in the Liver.
Frontiers in pharmacology
Cheng Z,Luo X,Zhu Z,Huang Y,Yan X
Sat Jul 16 00:00:00 EDT 2022
FTO protects human granulosa cells from chemotherapy-induced cytotoxicity.
Reproductive biology and endocrinology : RB&E
Wang R,Wang W,Wang L,Yuan L,Cheng F,Guan X,Zheng N,Yang X
Sat Feb 26 00:00:00 EST 2022
A novel synthetic chalcone derivative, 2,4,6-trimethoxy-4'-nitrochalcone (Ch-19), exerted anti-tumor effects through stimulating ROS accumulation and inducing apoptosis in esophageal cancer cells.
Cell stress & chaperones
Yang Y,Wu H,Zou X,Chen Y,He R,Jin Y,Zhou B,Ge C,Yang Y
Tue Nov 01 00:00:00 EDT 2022
Protective Effect of Flavonoids against Methylglyoxal-Induced Oxidative Stress in PC-12 Neuroblastoma Cells and Its Structure-Activity Relationships.
Molecules (Basel, Switzerland)
Zhang D,Li X,He X,Xing Y,Jiang B,Xiu Z,Bao Y,Dong Y
Sat Nov 12 00:00:00 EST 2022
Harpagoside Protects Against Doxorubicin-Induced Cardiotoxicity via P53-Parkin-Mediated Mitophagy.
Frontiers in cell and developmental biology
Li W,Wang X,Liu T,Zhang Q,Cao J,Jiang Y,Sun Q,Li C,Wang W,Wang Y
Tue Mar 01 00:00:00 EST 2022
The Photoperiod Regulates Granulosa Cell Apoptosis through the FSH-Nodal/ALK7 Signaling Pathway in Phodopus sungorus.
Animals : an open access journal from MDPI
Qi Y,Xue HL,Zheng YJ,Yin YF,Xu WL,Xu JH,Wu M,Chen L,Xu LX
Fri Dec 16 00:00:00 EST 2022
SERPINA5 promotes tumour cell proliferation by modulating the PI3K/AKT/mTOR signalling pathway in gastric cancer.
Journal of cellular and molecular medicine
Fan M,Xiong X,Han L,Zhang L,Gao S,Liu L,Wang X,Huang C,Tong D,Yang J,Zhao L,Shao Y
Thu Sep 01 00:00:00 EDT 2022
Integrative investigation of the TF-miRNA coregulatory network involved in the inhibition of breast cancer cell proliferation by resveratrol.
FEBS open bio
Zhou Y,Zhang J,Li W,Zhang D,Wang Z,Zhai Y,Yu H,Li Z
Tue Feb 01 00:00:00 EST 2022
Proanthocyanidins inhibit the apoptosis and aging of nucleus pulposus cells through the PI3K/Akt pathway delaying intervertebral disc degeneration.
Connective tissue research
Chen HW,Liu MQ,Zhang GZ,Zhang CY,Wang ZH,Lin AX,Kang JH,Liu WZ,Guo XD,Wang YD,Kang XW
Tue Nov 01 00:00:00 EDT 2022
Expression and potential role of FOSB in glioma.
Frontiers in molecular neuroscience
Qi M,Sun LA,Zheng LR,Zhang J,Han YL,Wu F,Zhao J,Niu WH,Fei MX,Jiang XC,Zhou ML
Wed Nov 02 00:00:00 EDT 2022
GDF-15 in tumor-derived exosomes promotes muscle atrophy via Bcl-2/caspase-3 pathway.
Cell death discovery
Zhang W,Sun W,Gu X,Miao C,Feng L,Shen Q,Liu X,Zhang X
Mon Apr 04 00:00:00 EDT 2022
Discoidin domain receptor 1(DDR1) promote intestinal barrier disruption in Ulcerative Colitis through tight junction proteins degradation and epithelium apoptosis.
Pharmacological research
Li X,Li Q,Xiong B,Chen H,Wang X,Zhang D
Thu Sep 01 00:00:00 EDT 2022
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
Microvascular research
Zhou YH,Tang YZ,Guo LY,Zheng LL,Zhang D,Yang CY,Wang W
Sat Jan 01 00:00:00 EST 2022
6-Shogaol Exhibits a Promoting Effect with Tax via Binding HSP60 in Non-Small-Cell Lung Cancer.
Cells
Mulati S,Jiang R,Wang J,Tao Y,Zhang W
Sat Nov 19 00:00:00 EST 2022
A derivant of ginsenoside CK and its inhibitory effect on hepatocellular carcinoma.
Life sciences
Zhang J,Tong Y,Lu X,Dong F,Ma X,Yin S,He Y,Liu Y,Liu Q,Fan D
Thu Sep 01 00:00:00 EDT 2022
Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway.
Aging
Yang L,Wang Q,Zhao Q,Yang F,Liu T,Huang X,Yan Q,Yang X
Tue Jan 04 00:00:00 EST 2022
NEDD4 attenuates phosgene-induced acute lung injury through the inhibition of Notch1 activation.
Journal of cellular and molecular medicine
Shao Y,Jiang Z,He D,Shen J
Sun May 01 00:00:00 EDT 2022
Trimethylamine N-oxide promotes hyperoxaluria-induced calcium oxalate deposition and kidney injury by activating autophagy.
Free radical biology & medicine
Dong F,Jiang S,Tang C,Wang X,Ren X,Wei Q,Tian J,Hu W,Guo J,Fu X,Liu L,Patzak A,Persson PB,Gao F,Lai EY,Zhao L
Tue Feb 01 00:00:00 EST 2022
Identification of a heterozygous variant of ZP2 as a novel cause of empty follicle syndrome in humans and mice.
Human reproduction (Oxford, England)
Shen Y,Guo J,Zhang X,Wang X,Zhu S,Chen D,Xiong W,Lu G,Liu X,Dai C,Gong F,Wang Y,Lin G,Wang Z,Xu W
Fri Apr 01 00:00:00 EDT 2022
Harnessing chlorin e6 loaded by functionalized iron oxide nanoparticles linked with glucose for target photodynamic therapy and improving of the immunogenicity of lung cancer.
Journal of cancer research and clinical oncology
Yu TT,Peng XC,Wang MF,Han N,Xu HZ,Li QR,Li LG,Xu X,Ma QL,Liu B,Wang J,Zhao L,Chen X,Li TF
Fri Apr 01 00:00:00 EDT 2022
Harnessing chlorin e6 loaded by functionalized iron oxide nanoparticles linked with glucose for target photodynamic therapy and improving of the immunogenicity of lung cancer.
Journal of cancer research and clinical oncology
Yu TT,Peng XC,Wang MF,Han N,Xu HZ,Li QR,Li LG,Xu X,Ma QL,Liu B,Wang J,Zhao L,Chen X,Li TF
Fri Apr 01 00:00:00 EDT 2022
Exosomes Derived from Bone Marrow Mesenchymal Stem Cells Alleviate Ischemia-Reperfusion Injury and Promote Survival of Skin Flaps in Rats.
Life (Basel, Switzerland)
Niu Q,Yang Y,Li D,Guo W,Wang C,Xu H,Feng Z,Han Z
Sun Oct 09 00:00:00 EDT 2022
Effect of alfalfa substituted with ramie on the expression of apoptotic genes in the gastrointestinal tracts of goats.
Food science & nutrition
Liu Q,Fu C,Yang H,Zhou C,Kang J,Chen L,Kong Z,Tan Z,Tang S
Fri Jul 01 00:00:00 EDT 2022
Targeting and neutralizing human epididymis protein 4 by novel nanobodies to suppress ovarian cancer cells and attenuate cisplatin resistance.
International journal of biological macromolecules
Yu J,Guo Y,Gu Y,Li F,Song H,Nian R,Fan X,Liu W
Mon Feb 28 00:00:00 EST 2022
SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism.
Scientific reports
Cai G,Ge Z,Xu Y,Cai L,Sun P,Huang G
Sat Jul 16 00:00:00 EDT 2022
Yap is essential for uterine decidualization through Rrm2/GSH/ROS pathway in response to Bmp2.
International journal of biological sciences
Yu HF,Yang ZQ,Xu MY,Huang JC,Yue ZP,Guo B
Thu Apr 14 00:00:00 EDT 2022
Investigation of the inhibition effect of 1,2,3,4,6-pentagalloyl-β-D-glucose on gastric cancer cells based on a network pharmacology approach and experimental validation.
Frontiers in oncology
Bi JH,Jiang YH,Ye SJ,Wu MR,Yi Y,Wang HX,Wang LM
Tue Aug 23 00:00:00 EDT 2022
Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A.
European journal of pharmacology
Huang Y,Chen S,Pang L,Feng Z,Su H,Zhu W,Wei J
Tue Feb 15 00:00:00 EST 2022
3-iodothyronamine inhibits apoptosis induced by myocardial ischemia reperfusion via the Akt/FoxO1 signaling pathway.
Annals of translational medicine
Zhou H,Mo L,Huang N,Zou C,Li C,Lin M,Zhang B,Wei B,Li P,Si X,Chen J,Li W,Liu X,Hu B
Tue Feb 01 00:00:00 EST 2022
Spermidine Alleviates Intrauterine Hypoxia-Induced Offspring Newborn Myocardial Mitochondrial Damage in Rats by Inhibiting Oxidative Stress and Regulating Mitochondrial Quality Control.
Iranian journal of pharmaceutical research : IJPR
Chai N,Zheng H,Zhang H,Li L,Yu X,Wang L,Bi X,Yang L,Niu T,Liu X,Zhao Y,Dong L
Thu Dec 01 00:00:00 EST 2022
Tanshinone IIA Accomplished Protection against Radiation-Induced Cardiomyocyte Injury by Regulating the p38/p53 Pathway.
Mediators of inflammation
Wang G,Ma L,Wang B,Gao F,Li J,Cai H,Wang J,Zhang T,Guo H,Xie P,Li Y
Wed Sep 07 00:00:00 EDT 2022
Novel Flavan-3,4-diol vernicidin B from Toxicodendron Vernicifluum (Anacardiaceae) as potent antioxidant via IL-6/Nrf2 cross-talks pathways.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhong T,Li M,Wu H,Wang D,Liu J,Xu Y,Fan Y
Wed Jun 01 00:00:00 EDT 2022
Plasma-Based Metabolomics Profiling of High-Risk Human Papillomavirus and their Emerging Roles in the Progression of Cervical Cancer.
BioMed research international
Chen A,Xu M,Chen J,Chen T,Wang Q,Zhang R,Qiu J
Mon Nov 21 00:00:00 EST 2022
Danggui Niantong granules ameliorate rheumatoid arthritis by regulating intestinal flora and promoting mitochondrial apoptosis.
Pharmaceutical biology
Lu QJ,Li JY,Lin HX,Cai YS,Liu CS,Fu LP,Liu G,Yuan LX
Thu Dec 01 00:00:00 EST 2022
Danggui Niantong granules ameliorate rheumatoid arthritis by regulating intestinal flora and promoting mitochondrial apoptosis.
Pharmaceutical biology
Lu QJ,Li JY,Lin HX,Cai YS,Liu CS,Fu LP,Liu G,Yuan LX
Thu Dec 01 00:00:00 EST 2022
Oxidative stress activates Ryr2-Ca2+ and apoptosis to promote PM2.5-induced heart injury of hyperlipidemia mice.
Ecotoxicology and environmental safety
Meng M,Jia R,Wei M,Meng X,Zhang X,Du R,Sun W,Wang L,Song L
Tue Mar 01 00:00:00 EST 2022
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
International journal of biological sciences
Gou W,Luo N,Yu B,Wu H,Wu S,Tian C,Guo J,Ning H,Bi C,Wei H,Hou W,Li Y
Thu Apr 14 00:00:00 EDT 2022
PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop.
Cancer communications (London, England)
Zhao X,Shu D,Sun W,Si S,Ran W,Guo B,Cui L
Sat Oct 01 00:00:00 EDT 2022
Salidroside inhibited cerebral ischemia/reperfusion-induced oxidative stress and apoptosis via Nrf2/Trx1 signaling pathway.
Metabolic brain disease
Li F,Mao Q,Wang J,Zhang X,Lv X,Wu B,Yan T,Jia Y
Thu Dec 01 00:00:00 EST 2022
Berberine inhibits gastric cancer development and progression by regulating the JAK2/STAT3 pathway and downregulating IL-6.
Life sciences
Xu M,Ren L,Fan J,Huang L,Zhou L,Li X,Ye X
Tue Feb 01 00:00:00 EST 2022
Covalent Organic Framework (COF): A Drug and Carrier to Attenuate Retinal Ganglion Cells Death in an Acute Glaucoma Mouse Model.
Polymers
Yao K,Liang X,Zhang G,Rong Y,Zhang Q,Liao Q,Zhang H,Xi K,Wang J
Wed Aug 10 00:00:00 EDT 2022
Metformin Exhibits an Attractive Antineoplastic Effect on Human Endometrial Cancer by Regulating the Hippo Signaling Pathway.
Journal of oncology
Wang M,Zhang Q,Li Y,Jin L,Fang Z
Fri Oct 14 00:00:00 EDT 2022
Agonists Specific for κ-Opioid Receptor Induces Apoptosis of HCC Cells Through Enhanced Endoplasmic Reticulum Stress.
Frontiers in oncology
Tan M,Wang H,Gao C,Jiang Z,Yin Y,Xing R,Hu L,Xu J,Zhang M,Xie Y
Thu Jun 16 00:00:00 EDT 2022
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m6A modification.
Bone
He Y,Wang W,Xu X,Yang B,Yu X,Wu Y,Wang J
Sat Jan 01 00:00:00 EST 2022
Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression.
Cellular and molecular gastroenterology and hepatology
Luo J,Li L,Chang B,Zhu Z,Deng F,Hu M,Yu Y,Lu X,Chen Z,Zuo D,Zhou J
Mon Jun 20 00:00:00 EDT 2022
P2RY13 Exacerbates Intestinal Inflammation by Damaging the Intestinal Mucosal Barrier via Activating IL-6/STAT3 Pathway.
International journal of biological sciences
Wu X,Wei S,Chen M,Li J,Wei Y,Zhang J,Dong W
Mon Aug 22 00:00:00 EDT 2022
Hace1 overexpression mitigates myocardial hypoxia/reoxygenation injury via the effects on Keap1/Nrf2 pathway.
In vitro cellular & developmental biology. Animal
Chen TY,Zheng SK
Sat Oct 01 00:00:00 EDT 2022
Protective effects of 5(S)-5-carboxystrictosidine on myocardial ischemia-reperfusion injury through activation of mitochondrial KATP channels.
European journal of pharmacology
Han Y,Li C,Zhang P,Yang X,Min J,Wu Q,Xie Y,Jin D,Wang Z,Shao F,Quan H
Tue Apr 05 00:00:00 EDT 2022
Effect of thymoquinone on sepsis-induced cardiac damage via anti-inflammatory and anti-apoptotic mechanisms.
The Journal of international medical research
Guo W,Long X,Lv M,Deng S,Liu D,Yang Q
Thu Sep 01 00:00:00 EDT 2022
Effect of thymoquinone on sepsis-induced cardiac damage via anti-inflammatory and anti-apoptotic mechanisms.
The Journal of international medical research
Guo W,Long X,Lv M,Deng S,Liu D,Yang Q
Thu Sep 01 00:00:00 EDT 2022
Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma.
Cell death & disease
Jia X,Xin M,Xu J,Xiang X,Li X,Jiao Y,Wang L,Jiang J,Pang F,Zhang X,Zhang J
Tue Aug 30 00:00:00 EDT 2022
Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhan L,Pu J,Zheng J,Hang S,Pang L,Dai M,Ji C
Fri Apr 01 00:00:00 EDT 2022
Cyclic Polypeptide D7 Protects Bone Marrow Mesenchymal Cells and Promotes Chondrogenesis during Osteonecrosis of the Femoral Head via Growth Differentiation Factor 15-Mediated Redox Signaling.
Oxidative medicine and cellular longevity
Chen J,Cui Z,Wang Y,Lyu L,Feng C,Feng D,Cheng Y,Li Z,Sun S
Thu Mar 24 00:00:00 EDT 2022
Valdecoxib Protects against Cell Apoptosis Induced by Endoplasmic Reticulum Stress via the Inhibition of PERK-ATF4-CHOP Pathway in Experimental Glaucoma.
International journal of molecular sciences
Gao Z,Li M,Yao F,Xia X,Duan T,Meng J,Huang Y,He Y,Saro A,Huang J
Wed Oct 26 00:00:00 EDT 2022
Biotransformation of graphene oxide within lung fluids could intensify its synergistic biotoxicity effect with cadmium by inhibiting cellular efflux of cadmium.
Environmental pollution (Barking, Essex : 1987)
Zhu J,Liu L,Ma J,Fu Q,Zheng Z,Du E,Xu Y,Zhang Z
Mon Aug 01 00:00:00 EDT 2022
Glis2 inhibits the epithelial-mesenchymal transition and apoptosis of renal tubule cells by regulating the β-catenin signalling pathway in diabetic kidney disease.
Biochemical and biophysical research communications
He L,Li Q,Du C,Xue Y,Yu P
Sat Jun 04 00:00:00 EDT 2022
Glis2 inhibits the epithelial-mesenchymal transition and apoptosis of renal tubule cells by regulating the β-catenin signalling pathway in diabetic kidney disease.
Biochemical and biophysical research communications
He L,Li Q,Du C,Xue Y,Yu P
Sat Jun 04 00:00:00 EDT 2022
CSTF2 Acts as a Prognostic Marker Correlated with Immune Infiltration in Hepatocellular Carcinoma.
Cancer management and research
Zhang W,Wan Y,Zhang Y,Liu Q,Zhu X
Tue Sep 20 00:00:00 EDT 2022
HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance.
Frontiers in pharmacology
Shi B,Xu FF,Xiang CP,Li CY,Fan P,Wang H
Fri Apr 01 00:00:00 EDT 2022
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Biochemical pharmacology
Ni L,Lin Z,Hu S,Shi Y,Jiang Z,Zhao J,Zhou Y,Wu Y,Tian N,Sun L,Wu A,Pan Z,Zhang X,Wang X
Fri Apr 01 00:00:00 EDT 2022
MiR-1306-5p promotes cell proliferation and inhibits cell apoptosis in acute myeloid leukemia by downregulating PHF6 expression.
Leukemia research
Gao X,Fan S,Zhang X
Thu Sep 01 00:00:00 EDT 2022
Long-Term Consumption of Food-Derived Chlorogenic Acid Protects Mice against Acetaminophen-Induced Hepatotoxicity via Promoting PINK1-Dependent Mitophagy and Inhibiting Apoptosis.
Toxics
Hu B,Li J,Gong D,Dai Y,Wang P,Wan L,Xu S
Sat Nov 05 00:00:00 EDT 2022
SLC4A4 promotes prostate cancer progression in vivo and in vitro via AKT-mediated signalling pathway.
Cancer cell international
Liu Z,Wang Q,Zhai G,Ke S,Yu X,Guo J
Sat Mar 19 00:00:00 EDT 2022
Yajieshaba prevents lipopolysaccharide-induced intestinal barrier injuryanti-inflammatory and anti-apoptosis.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Liping Y,Xinglin YU,Chao Z,Pu C,Xiaohua D
Sat Oct 01 00:00:00 EDT 2022
Grifola frondosa Polysaccharide Ameliorates Early Diabetic Nephropathy by Suppressing the TLR4/NF-κB Pathway.
Applied biochemistry and biotechnology
Jiang T,Shen S,Wang L,Zhao M,Li Y,Huang S
Thu Sep 01 00:00:00 EDT 2022
Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1.
Frontiers in pharmacology
Zhou J,Wang Y,Zhang L,Chen Q,Zhu X,Jiang P,Jiang N,Zhao W,Li B
Sat Jul 16 00:00:00 EDT 2022
Zearalenone Promotes LPS-Induced Oxidative Stress, Endoplasmic Reticulum Stress, and Accelerates Bovine Mammary Epithelial Cell Apoptosis.
International journal of molecular sciences
Fu Y,Jin Y,Tian Y,Yu H,Wang R,Qi H,Feng B,Zhang J
Sun Sep 18 00:00:00 EDT 2022
Adiponectin/AdiopR1 signaling prevents mitochondrial dysfunction and oxidative injury after traumatic brain injury in a SIRT3 dependent manner.
Redox biology
Zhang S,Wu X,Wang J,Shi Y,Hu Q,Cui W,Bai H,Zhou J,Du Y,Han L,Li L,Feng D,Ge S,Qu Y
Mon Aug 01 00:00:00 EDT 2022
Downregulation of NCL attenuates tumor formation and growth in HeLa cells by targeting the PI3K/AKT pathway.
Cancer medicine
Ying J,Pan R,Tang Z,Zhu J,Ren P,Lou Y,Zhang E,Huang D,Hu P,Li D,Bao Q,Li P
Tue Mar 01 00:00:00 EST 2022
HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3.
Experimental & molecular medicine
Hu B,Wang P,Zhang S,Liu W,Lv X,Shi D,Zhao L,Liu H,Wang B,Chen S,Shao Z
Tue Mar 01 00:00:00 EST 2022
A comprehensive analysis on the relationship between BDE-209 exposure and erectile dysfunction.
Chemosphere
Zhou X,Song L,Cong R,Luan J,Zhou X,Wang Y,Yao L,Zhang X,Ren X,Zhang T,Yu M,Song N
Thu Dec 01 00:00:00 EST 2022
Tumor-targeted dual-starvation therapy based on redox-responsive micelle nanosystem with co-loaded LND and BPTES.
Materials today. Bio
Fu Z,Du H,Meng S,Yao M,Zhao P,Li X,Zheng X,Yuan Z,Yang H,Cai K,Dai L
Thu Dec 01 00:00:00 EST 2022
Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhan L,Zheng J,Meng J,Fu D,Pang L,Ji C
Tue Nov 01 00:00:00 EDT 2022
CEMIP Promotes Osteosarcoma Progression and Metastasis Through Activating Notch Signaling Pathway.
Frontiers in oncology
Cheng J,Zhang Y,Wan R,Zhou J,Wu X,Fan Q,He J,Tan W,Deng Y
Sat Aug 13 00:00:00 EDT 2022
Bixin Prevents Colorectal Cancer Development through AMPK-Activated Endoplasmic Reticulum Stress.
BioMed research international
Qiu Y,Li C,Zhang B
Fri Apr 08 00:00:00 EDT 2022
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
Veterinary microbiology
Li Y,Zhu Y,Chu B,Liu N,Chen S,Wang J
Tue Mar 01 00:00:00 EST 2022
Colistin-induced pulmonary toxicity involves the activation of NOX4/TGF-β/mtROS pathway and the inhibition of Akt/mTOR pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Dai C,Li M,Sun T,Zhang Y,Wang Y,Shen Z,Velkov T,Tang S,Shen J
Sun May 01 00:00:00 EDT 2022
Colistin-induced pulmonary toxicity involves the activation of NOX4/TGF-β/mtROS pathway and the inhibition of Akt/mTOR pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Dai C,Li M,Sun T,Zhang Y,Wang Y,Shen Z,Velkov T,Tang S,Shen J
Sun May 01 00:00:00 EDT 2022
Role of Mydgf in the regulation of hypoxia/reoxygenation-induced apoptosis in cardiac microvascular endothelial cells.
In vitro cellular & developmental biology. Animal
Wang Y,Zhang Y,Li J,Zhao R,Long X,Li C,Liu W,Chen W,Shi B
Thu Sep 01 00:00:00 EDT 2022
MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A.
Journal of advanced research
Ayesha M,Majid A,Zhao D,Greenaway FT,Yan N,Liu Q,Liu S,Sun MZ
Tue Feb 01 00:00:00 EST 2022
LncRNA SOX2OT facilitates LPS-induced inflammatory injury by regulating intercellular adhesion molecule 1 (ICAM1) via sponging miR-215-5p.
Clinical immunology (Orlando, Fla.)
Zhu W,Peng F,Cui X,Li J,Sun C
Sun May 01 00:00:00 EDT 2022
Inhibition of Ceramide Glycosylation Enhances Cisplatin Sensitivity in Cholangiocarcinoma by Limiting the Activation of the ERK Signaling Pathway.
Life (Basel, Switzerland)
Chueakwon P,Jatooratthawichot P,Talabnin K,Ketudat Cairns JR,Talabnin C
Mon Feb 28 00:00:00 EST 2022
Sparstolonin B inhibits pancreatic adenocarcinoma through the NF-κB signaling pathway.
Experimental cell research
Lyu Y,Duan B,Liu Z,Yang F,Chen C,Jiang X,Liu X
Mon Aug 01 00:00:00 EDT 2022
Porcine cGAS-STING signaling induced autophagy inhibits STING downstream IFN and apoptosis.
Frontiers in immunology
Xia N,Zheng W,Jiang S,Cao Q,Luo J,Zhang J,Xu Y,Sun S,Zhang K,Chen N,Meurens F,Zhu J
Tue Nov 01 00:00:00 EDT 2022
BAY61‑3606 attenuates neuroinflammation and neurofunctional damage by inhibiting microglial Mincle/Syk signaling response after traumatic brain injury.
International journal of molecular medicine
He X,Huang Y,Liu Y,Zhang X,Yue P,Ma X,Miao Z,Long X,Yang Y,Wan X,Lei J,Shu K,Lei T,Gan C,Zhang H
Sat Jan 01 00:00:00 EST 2022
Knockdown of forkhead box protein P1 alleviates hypoxia reoxygenation injury in H9c2 cells through regulating Pik3ip1/Akt/eNOS and ROS/mPTP pathway.
Bioengineered
Liu X,Yang Y,Song J,Li D,Liu X,Li C,Ma Z,Zhong J,Wang L
Sat Jan 01 00:00:00 EST 2022
The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids.
Microbiome
Xiao W,Su J,Gao X,Yang H,Weng R,Ni W,Gu Y
Sun Apr 17 00:00:00 EDT 2022
Diffractaic acid, a novel TrxR1 inhibitor, induces cytotoxicity, apoptosis, and antimigration in human breast cancer cells.
Chemico-biological interactions
Kalın ŞN,Altay A,Budak H
Fri Jul 01 00:00:00 EDT 2022
HSP90-Mediates Liraglutide Preconditioning-Induced Cardioprotection by Inhibiting C5a and NF-κB.
Journal of investigative surgery : the official journal of the Academy of Surgical Research
He ST,Wang DX,Meng JJ,Cheng XF,Bi Q,Zhong GQ,Tu RH
Sun May 01 00:00:00 EDT 2022
TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma.
Cancer cell international
Tong Q,Yi M,Kong P,Xu L,Huang W,Niu Y,Gan X,Zhan H,Tian R,Yan D
Tue Sep 06 00:00:00 EDT 2022
DJ-1 Protein Inhibits Apoptosis in Cerebral Ischemia by Regulating the Notch1 and Nuclear Factor Erythroid2-Related Factor 2 Signaling Pathways.
Neuroscience
Wang T,Xue Y,Li Y,Gao S,Peng L,Zhao Y,Yu S
Thu Nov 10 00:00:00 EST 2022
Dihydrohomoplantagin and Homoplantaginin, Major Flavonoid Glycosides from Salvia plebeia R. Br. Inhibit oxLDL-Induced Endothelial Cell Injury and Restrict Atherosclerosis via Activating Nrf2 Anti-Oxidation Signal Pathway.
Molecules (Basel, Switzerland)
Meng N,Chen K,Wang Y,Hou J,Chu W,Xie S,Yang F,Sun C
Sat Mar 19 00:00:00 EDT 2022
Single-nucleus RNA Sequencing reveals the mechanism of cigarette smoke exposure on diminished ovarian reserve in mice.
Ecotoxicology and environmental safety
Li F,Wang Y,Xu M,Hu N,Miao J,Zhao Y,Wang L
Sat Oct 15 00:00:00 EDT 2022
Genistein alleviates renin-angiotensin system mediated vascular and kidney alterations in renovascular hypertensive rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Poasakate A,Maneesai P,Potue P,Bunbupha S,Tong-Un T,Settheetham-Ishida W,Khamseekaew J,Pakdeechote P
Tue Feb 01 00:00:00 EST 2022
Salidroside alleviates oxidative stress and apoptosis via AMPK/Nrf2 pathway in DHT-induced human granulosa cell line KGN.
Archives of biochemistry and biophysics
Ji R,Jia FY,Chen X,Wang ZH,Jin WY,Yang J
Sat Jan 15 00:00:00 EST 2022
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.
Aging
Jiang XL,Tai H,Kuang JS,Zhang JY,Cui SC,Lu YX,Qi SB,Zhang SY,Li SM,Chen JP,Meng XS
Thu Oct 27 00:00:00 EDT 2022
Network Pharmacology Analysis and Experimental Validation of Kaempferol in the Treatment of Ischemic Stroke by Inhibiting Apoptosis and Regulating Neuroinflammation Involving Neutrophils.
International journal of molecular sciences
Zhang SS,Liu M,Liu DN,Shang YF,Du GH,Wang YH
Fri Oct 21 00:00:00 EDT 2022
Effects of betaine on viability, apoptosis, function protein expression and oxidative status in heat-stressed IEC-6 cells.
Journal of thermal biology
Sun S,Yin Q,Li B,Deng Y,Li J,Xiong Y,Shaojun H
Thu Dec 01 00:00:00 EST 2022
NaAsO2 decreases GSH synthesis by inhibiting GCLC and induces apoptosis through Hela cell mitochondrial damage, mediating the activation of the NF-κB/miR-21 signaling pathway.
Ecotoxicology and environmental safety
Ran S,Gao X,Ma M,Zhang J,Li S,Zhang M,Li S
Fri Apr 01 00:00:00 EDT 2022
Evodiamine as the Active Compound of Evodiae fructus to Inhibit Proliferation and Migration of Prostate Cancer through PI3K/AKT/NF-κB Signaling Pathway.
Disease markers
Lei Y,Chan M,Liu H,Lyu W,Chen L,Zhong Y,Gan H,Wang M,Qi M,Guo Y,Liu J,Zhang E
Fri Jul 29 00:00:00 EDT 2022
Sevelamer arsenite nanoparticle as a Pi-responsive drug carrier and embolic agent for chemoembolization.
Drug delivery
Bi QC,Tang JJ,Zhao J,Lv YF,Deng ZQ,Chen H,Xu YH,Xie CS,Liang QR,Luo RG,Tang Q
Thu Dec 01 00:00:00 EST 2022
Molecular Mechanism of Aluminum-Induced Oxidative Damage and Apoptosis in Rat Cardiomyocytes.
Biological trace element research
Zhou L,He M,Li X,Lin E,Wang Y,Wei H,Wei X
Sat Jan 01 00:00:00 EST 2022
Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice.
Laboratory investigation; a journal of technical methods and pathology
Deng YW,Liu F,Li ZT,Gao JH,Zhao Y,Yang XL,Xia YL
Tue Nov 01 00:00:00 EDT 2022
Magnesium isoglycyrrhizinate ameliorates lipopolysaccharide-induced liver injury by upregulating autophagy and inhibiting inflammation via IL-22 expression.
Bioorganic chemistry
Zhou X,Li X,Yi K,Liang C,Geng S,Zhu J,Xie C,Zhong C
Tue Nov 01 00:00:00 EDT 2022
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Frontiers in physiology
Guo J,Hu H,Chen Z,Xu J,Nie J,Lu J,Ma L,Ji H,Yuan J,Xu B
Sat Jul 16 00:00:00 EDT 2022
Polymyxin B Reduces Brain Injury in Ischemic Stroke Rat Through a Mechanism Involving Targeting ESCRT-III Machinery and RIPK1/RIPK3/MLKL Pathway.
Journal of cardiovascular translational research
Tian J,Zhang YY,Peng YW,Liu B,Zhang XJ,Hu ZY,Hu CP,Luo XJ,Peng J
Sat Oct 01 00:00:00 EDT 2022
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro.
Pharmaceutical biology
Yang Y,Ren ZZ,Wei WJ,He ZL,Deng YL,Wang Z,Fan YC,Zhou J,Jiang LH
Thu Dec 01 00:00:00 EST 2022
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Oxidative medicine and cellular longevity
Mao Y,Du J,Chen X,Al Mamun A,Cao L,Yang Y,Mubwandarikwa J,Zaeem M,Zhang W,Chen Y,Dai Y,Xiao J,Ye K
Fri Mar 18 00:00:00 EDT 2022
Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway.
Life sciences
Zhu M,Niu J,Jiang J,Dong T,Chen Y,Yang X,Liu P
Tue Mar 15 00:00:00 EDT 2022
Targeting the splicing factor NONO inhibits GBM progression through GPX1 intron retention.
Theranostics
Wang X,Han M,Wang S,Sun Y,Zhao W,Xue Z,Liang X,Huang B,Li G,Chen A,Li X,Wang J
Tue Aug 02 00:00:00 EDT 2022
NAD(P)H: quinone oxidoreductase 1 attenuates oxidative stress and apoptosis by regulating Sirt1 in diabetic nephropathy.
Journal of translational medicine
Qiu D,Song S,Wang Y,Bian Y,Wu M,Wu H,Shi Y,Duan H
Fri Jan 28 00:00:00 EST 2022
NAD(P)H: quinone oxidoreductase 1 attenuates oxidative stress and apoptosis by regulating Sirt1 in diabetic nephropathy.
Journal of translational medicine
Qiu D,Song S,Wang Y,Bian Y,Wu M,Wu H,Shi Y,Duan H
Fri Jan 28 00:00:00 EST 2022
TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling.
Clinics (Sao Paulo, Brazil)
Wang X,Fu Y,Xing Y
Mon Oct 31 00:00:00 EDT 2022
A bavachinin analog, D36, induces cell death by targeting both autophagy and apoptosis pathway in acute myeloid leukemia cells.
Cancer chemotherapy and pharmacology
Zhang W,Liu J,Li Y,Guo F
Thu Sep 01 00:00:00 EDT 2022
The bibenzyl derivatives of Dendrobium officinale prevent UV-B irradiation induced photoaging via SIRT3.
Natural products and bioprospecting
Chen DK,Shao HY,Yang L,Hu JM
Thu Jan 27 00:00:00 EST 2022
Melatonin promotes sirtuin 1 expression and inhibits IRE1α-XBP1S-CHOP to reduce endoplasmic reticulum stress-mediated apoptosis in chondrocytes.
Frontiers in pharmacology
Qin K,Tang H,Ren Y,Yang D,Li Y,Huang W,Wu Y,Yin Z
Tue Aug 30 00:00:00 EDT 2022
LncRNA HIF1A-AS1 Regulates the Cellular Function of HUVECs by Globally Regulating mRNA and miRNA Expression.
Frontiers in bioscience (Landmark edition)
Gong Z,Yang J,Dong J,Li H,Wang B,Du K,Zhang C,Chen L
Wed Dec 21 00:00:00 EST 2022
HB-EGF induces mitochondrial dysfunction via estrogen hypersecretion in granulosa cells dependent on cAMP-PKA-JNK/ERK-Ca2+-FOXO1 pathway.
International journal of biological sciences
Huang JC,Duan CC,Jin S,Sheng CB,Wang YS,Yue ZP,Guo B
Fri Apr 15 00:00:00 EDT 2022
Maintaining homeostasis of mitochondria and endoplasmic reticulum with NSC228155 alleviates cisplatin-induced acute kidney injury.
Free radical biology & medicine
Li Y,Jiang Y,Zhou W,Wu Y,Zhang S,Ding G,Zhang Y,Zhang A,Huang S,Jia Z,You R
Tue Mar 01 00:00:00 EST 2022
A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin.
Journal of nanobiotechnology
Yang XX,Xu X,Wang MF,Xu HZ,Peng XC,Han N,Yu TT,Li LG,Li QR,Chen X,Wen Y,Li TF
Sat May 14 00:00:00 EDT 2022
A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin.
Journal of nanobiotechnology
Yang XX,Xu X,Wang MF,Xu HZ,Peng XC,Han N,Yu TT,Li LG,Li QR,Chen X,Wen Y,Li TF
Sat May 14 00:00:00 EDT 2022
Hesperidin partly ameliorates the decabromodiphenyl ether-induced reproductive toxicity in pubertal mice.
Environmental science and pollution research international
Li S,Che S,Chen S,Ruan Z,Zhang L
Thu Dec 01 00:00:00 EST 2022
Mitochondria-specific peptide amphiphiles induce mitochondrial dysfunction and peripheral T-cell lymphomas (PTCL) damage.
Annals of translational medicine
Sun Q,Gui A,Zou A,Yan Y,Qiu S,Zhu S,Liu W,Zuo J,Zhang Q,Yang L
Sun May 01 00:00:00 EDT 2022
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Biological trace element research
Xiong Y,Li J,He S
Tue Feb 01 00:00:00 EST 2022
Cystathionine β-Synthase Regulates the Proliferation, Migration, and Invasion of Thyroid Carcinoma Cells.
Oxidative medicine and cellular longevity
Jiang QY,Li JM,Jing MR,Zhang YX,Zhang QQ,Cai CB,Wang D,Qi HW,Li T,Li YZ,Ji XY,Wu DD
Fri Jul 08 00:00:00 EDT 2022
Sestrin2 remedies podocyte injury via orchestrating TSP-1/TGF-β1/Smad3 axis in diabetic kidney disease.
Cell death & disease
Song S,Shi C,Bian Y,Yang Z,Mu L,Wu H,Duan H,Shi Y
Sat Jul 30 00:00:00 EDT 2022
Interleukin-4 activates the PI3K/AKT signaling to promote apoptosis and inhibit the proliferation of granulosa cells.
Experimental cell research
Han Y,Yao R,Yang Z,Li S,Meng W,Zhang Y,Zhang Y,Luo H
Tue Mar 01 00:00:00 EST 2022
Grape Seed Proanthocyanidins Exert a Neuroprotective Effect by Regulating Microglial M1/M2 Polarisation in Rats with Spinal Cord Injury.
Mediators of inflammation
Liu WZ,Ma ZJ,Kang JH,Lin AX,Wang ZH,Chen HW,Guo XD,He XG,Kang XW
Tue Aug 16 00:00:00 EDT 2022
A mitochondria-targeted nano-platform for pancreatic cancer therapy.
Frontiers in chemistry
Tan X,Zhu X,Xu D,Shi Y,Wang Z,Cao M,Hu K,Zhao L,Zhao J,Miao M,Zeng H,Wu X
Tue Oct 11 00:00:00 EDT 2022
Protective Effects of Three Flavonoids from Dendrobium huoshanense Flowers on Alcohol-Induced Hepatocyte Injury via Activating Nrf2 and Inhibiting NF-κB Pathways.
Chemistry & biodiversity
Li QM,Yang XR,Zha XQ,Pan LH,Zang DD,Zhang FY,Luo JP
Mon Aug 01 00:00:00 EDT 2022
Calenduloside E alleviates cerebral ischemia/reperfusion injury by preserving mitochondrial function.
Journal of molecular histology
Li J,Bu Y,Li B,Zhang H,Guo J,Hu J,Zhang Y
Mon Aug 01 00:00:00 EDT 2022
Activated AXL Protects Against Hepatic Ischemia-reperfusion Injury by Upregulating SOCS-1 Expression.
Transplantation
Wang Z,Liu D,Yan Q,Liu F,Zhan M,Qi S,Fang Q,Yao L,Wang W,Zhang R,Du J,Chen L
Fri Jul 01 00:00:00 EDT 2022
MicroRNA-141-3p attenuates oxidative stress-induced hepatic ischemia reperfusion injury via Keap1/Nrf2 pathway.
Molecular biology reports
Li T,Chen Q,Dai J,Huang Z,Luo Y,Mou T,Pu J,Yang H,Wei X,Wu Z
Mon Aug 01 00:00:00 EDT 2022
Erectile dysfunction in hypospadiac male adult rats induced by maternal exposure to di-n-butyl phthalate.
Toxicology
Zhou X,Wang S,Zhou R,Zhang T,Wang Y,Zhang Q,Cong R,Ji C,Luan J,Yao L,Zhou X,Song N
Wed Jun 15 00:00:00 EDT 2022
NRF2-directed PRPS1 upregulation to promote the progression and metastasis of melanoma.
Frontiers in immunology
Xiong G,Feng Y,Yi X,Zhang X,Li X,Yang L,Yi Z,Sai B,Yang Z,Zhang Q,Kuang Y,Zhu Y
Mon Oct 10 00:00:00 EDT 2022
Chlorin e6 mediated photodynamic therapy triggers resistance through ATM-related DNA damage response in lung cancer cells.
Photodiagnosis and photodynamic therapy
Ma QL,Shen MO,Han N,Xu HZ,Peng XC,Li QR,Yu TT,Li LG,Xu X,Liu B,Chen X,Wang MF,Li TF
Tue Mar 01 00:00:00 EST 2022
An oleanolic acid derivative, K73-03, inhibits pancreatic cancer cells proliferation in vitro and in vivo via blocking EGFR/Akt pathway.
Cell biology international
Zhou Z,Dong Y,Li N,Niu M,Wang S,Zhou Y,Sun Z,Chu P,Tang Z
Tue Nov 01 00:00:00 EDT 2022
MicroRNA-21-5p agomir inhibits apoptosis of oligodendrocyte precursor cell and attenuates white matter injury in neonatal rats.
Brain research bulletin
Zhang F,Gou Z,Zhou Y,Huang L,Shao C,Wang M,Wu C,Lu L
Sat Oct 15 00:00:00 EDT 2022
Sleeve gastrectomy attenuated diabetes-related cognitive decline in diabetic rats.
Frontiers in endocrinology
Ding H,Liu C,Zhang S,Li B,Xu Q,Shi B,Li S,Dong S,Ma X,Zhang Y,Zhong M,Zhang G
Tue Nov 22 00:00:00 EST 2022
Metformin protects 5-Fu-induced chemotherapy oral mucositis by reducing endoplasmic reticulum stress in mice.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Sun H,Zhou Y,Ma R,Zhang J,Shan J,Chen Y,Li X,Shan E
Wed Jun 01 00:00:00 EDT 2022
Targeting IL8 as a sequential therapy strategy to overcome chemotherapy resistance in advanced gastric cancer.
Cell death discovery
Jiang H,Cui J,Chu H,Xu T,Xie M,Jing X,Xu J,Zhou J,Shu Y
Fri Apr 29 00:00:00 EDT 2022
Anticancer effects of myricetin derivatives in non-small cell lung cancer in vitro and in vivo.
Pharmacology research & perspectives
Li M,Zha G,Chen R,Chen X,Sun Q,Jiang H
Tue Feb 01 00:00:00 EST 2022
Artemisia capillaris Thunb. water extract attenuates adriamycin-induced renal injury by regulating apoptosis through the ROS/MAPK axis.
Journal of food biochemistry
Huang G,Zhu Y,Yong C,Tian F,Liu L,Wu Q,Shu Y,Yao M,Tang C,Wang X,Chen W,Zhou E
Tue Feb 01 00:00:00 EST 2022
Oxycodone relieves permeability damage and apoptosis of oxygen-glucose deprivation/reoxygenation-induced brain microvascular endothelial cells through ras homolog family member A (RhoA)/ Rho-associated coiled-coil containing kinases (ROCK)/ myosin light chain 2 (MLC2) signal.
Bioengineered
Shao F,Han D,Shen Y,Bian W,Zou L,Hu Y,Sun W
Tue Mar 01 00:00:00 EST 2022
IL-22 Protects against Biliary Ischemia-Reperfusion Injury after Liver Transplantation via Activating STAT3 and Reducing Apoptosis and Oxidative Stress Levels In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Bai Y,Wu H,Zhang J,Zhang S,Zhang Z,Wang H,Zhang Y,Shen Z
Mon May 23 00:00:00 EDT 2022
The effect of lncRNA MIR155HG-modified MSCs and exosome delivery to synergistically attenuate vein graft intimal hyperplasia.
Stem cell research & therapy
Bai X,Qi Z,Zhu M,Lu Z,Zhao X,Zhang L,Song G
Fri Nov 04 00:00:00 EDT 2022
Antagonistic effects of selenium on lead-induced oxidative stress and apoptosis of Leydig cells in sheep.
Theriogenology
Shi L,Wang X,Duan Y,Li K,Ren Y
Wed Jun 01 00:00:00 EDT 2022
Effect of NMB-regulated ERK1/2 and p65 signaling pathway on proliferation and apoptosis of cervical cancer.
Pathology, research and practice
Zeng R,Xiong X
Sat Oct 01 00:00:00 EDT 2022
4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis.
Cancer cell international
Li W,Huang BS,Xiong YY,Yang LJ,Wu LX
Tue Jan 18 00:00:00 EST 2022
Development of a Costimulatory Molecule Signature to Predict Prognosis, Immune Landscape, and Response to Immune Therapy for Hepatocellular Carcinoma.
Disease markers
Zhou Y,Zhou X,Liu Q,Zhang Z,Zhang W,Ma J,Yang M,Yu J,Luo J,Yan Z
Mon Sep 26 00:00:00 EDT 2022
Nrf2 Activation and NF-Kb & caspase/bax signaling inhibition by sodium butyrate alleviates LPS-induced cell injury in bovine mammary epithelial cells.
Molecular immunology
Ali I,Li C,Kuang M,Shah AU,Shafiq M,Ahmad MA,Abdalmegeed D,Li L,Wang G
Mon Aug 01 00:00:00 EDT 2022
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Frontiers in endocrinology
Jiang XL,Tai H,Xiao XS,Zhang SY,Cui SC,Qi SB,Hu DD,Zhang LN,Kuang JS,Meng XS,Li SM
Tue Dec 06 00:00:00 EST 2022
Regulation of Podocyte Injury by CircHIPK3/FUS Complex in Diabetic Kidney Disease.
International journal of biological sciences
Liu F,Huang J,Zhang C,Xie Y,Cao Y,Tao L,Tang H,Lin J,Hammes HP,Huang K,Yi F,Su H,Zhang C
Fri Oct 21 00:00:00 EDT 2022
Isolongifolene alleviates liver ischemia/reperfusion injury by regulating AMPK-PGC1α signaling pathway-mediated inflammation, apoptosis, and oxidative stress.
International immunopharmacology
Li J,Li J,Fang H,Yang H,Wu T,Shi X,Pang C
Thu Dec 01 00:00:00 EST 2022
A Network Pharmacology Approach for Uncovering the Antitumor Effects and Potential Mechanisms of the Sijunzi Decoction for the Treatment of Gastric Cancer.
Evidence-based complementary and alternative medicine : eCAM
Ding P,Guo Y,Wang C,Chen J,Guo C,Liu H,Shi Q
Sat Jul 16 00:00:00 EDT 2022
Delta Opioid Peptide Targets Brain Microvascular Endothelial Cells Reducing Apoptosis to Relieve Hypoxia-Ischemic/Reperfusion Injury.
Pharmaceutics
Zhang R,Chen M,Deng Z,Kong L,Shen B,Zhang L
Fri Dec 23 00:00:00 EST 2022
Kruppel-like factor 2 acts as a tumor suppressor in human retinoblastoma.
Experimental eye research
Wu N,Chen S,Luo Q,Jiang Z,Wang X,Li Y,Qiu J,Yu K,Yang Y,Zhuang J
Tue Mar 01 00:00:00 EST 2022
Upregulated circTMEM59 Inhibits Cell Growth and Metastasis by miR-668-3p/ID4 Axis in Colorectal Cancer.
Oxidative medicine and cellular longevity
Feng Y,Wang X,Huang C,Zhang D,Liu T,Zhang C,Zhang Y,Ji D,Tang J,Sun Y
Mon Jun 06 00:00:00 EDT 2022
Upregulated circTMEM59 Inhibits Cell Growth and Metastasis by miR-668-3p/ID4 Axis in Colorectal Cancer.
Oxidative medicine and cellular longevity
Feng Y,Wang X,Huang C,Zhang D,Liu T,Zhang C,Zhang Y,Ji D,Tang J,Sun Y
Mon Jun 06 00:00:00 EDT 2022
Upregulated circTMEM59 Inhibits Cell Growth and Metastasis by miR-668-3p/ID4 Axis in Colorectal Cancer.
Oxidative medicine and cellular longevity
Feng Y,Wang X,Huang C,Zhang D,Liu T,Zhang C,Zhang Y,Ji D,Tang J,Sun Y
Mon Jun 06 00:00:00 EDT 2022
Upregulated circTMEM59 Inhibits Cell Growth and Metastasis by miR-668-3p/ID4 Axis in Colorectal Cancer.
Oxidative medicine and cellular longevity
Feng Y,Wang X,Huang C,Zhang D,Liu T,Zhang C,Zhang Y,Ji D,Tang J,Sun Y
Mon Jun 06 00:00:00 EDT 2022
Electroacupuncture at Zusanli Alleviates Sepsis by Regulating the TLR4-MyD88-NF-Kappa B Pathway and Diversity of Intestinal Flora.
Evidence-based complementary and alternative medicine : eCAM
Zhan L,Liu H,Zheng J,Meng J,Fu D,Pang L,Ji C
Sat Jul 16 00:00:00 EDT 2022
Creatinine accelerates APAP-induced liver damage by increasing oxidative stress through ROS/JNK signaling pathway.
Frontiers in pharmacology
Liu F,Liu Y,Peng Q,Wang G,Tan Q,Ou Z,Xu Q,Liu C,Zuo D,Zhao J
Tue Sep 13 00:00:00 EDT 2022
Dietary Nε-(carboxymethyl) lysine affects cardiac glucose metabolism and myocardial remodeling in mice.
World journal of diabetes
Wang ZQ,Sun Z
Tue Nov 15 00:00:00 EST 2022
Asiaticoside ameliorates osteoarthritis progression through activation of Nrf2/HO-1 and inhibition of the NF-κB pathway.
International immunopharmacology
Luo P,Huang Q,Chen S,Wang Y,Dou H
Fri Jul 01 00:00:00 EDT 2022
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.
Frontiers in pharmacology
Lin X,Wei Y,Li Y,Xiong Y,Fang B,Li C,Huang Q,Huang R,Wei J
Sat Apr 02 00:00:00 EDT 2022
Anti-tumor effect of Yanggan Huayu granule by inducing AKT-mediated apoptosis in hepatocellular carcinoma.
Journal of ethnopharmacology
Shen Y,Yang F,Peng H,Zhang G,Zhu F,Xu H,Shi L
Mon Jan 10 00:00:00 EST 2022
Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway.
Bioengineered
Liu W,Feng Y,Wang X,Ding J,Li H,Guan H,Chen Z
Fri Apr 01 00:00:00 EDT 2022
HIV-1 gp120 Protein Activates Cyclin-Dependent Kinase 1, a Possible Link to Central Nervous System Cell Death.
Viruses
Saro A,Gao Z,Kambey PA,Li M,Huang J
Thu Dec 15 00:00:00 EST 2022
Depletion of serum-derived exosomes aggravates heat stress-induced damage of bovine mammary epithelial cells.
Molecular biology reports
Wang Y,Wang HL,Lin ZP,Zhong JF,Chen KL,Duan X
Sat Oct 01 00:00:00 EDT 2022
Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway.
Pharmaceutical biology
Bian Y,Xue M,Guo X,Jiang W,Zhao Y,Zhang Z,Wang X,Hu Y,Zhang Q,Dun W,Zhang L
Thu Dec 01 00:00:00 EST 2022
Asafoetida exerts neuroprotective effect on oxidative stress induced apoptosis through PI3K/Akt/GSK3β/Nrf2/HO-1 pathway.
Chinese medicine
Huang Q,Zhang C,Dong S,Han J,Qu S,Xie T,Zhao H,Shi Y
Wed Jul 06 00:00:00 EDT 2022
Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.
Materials today. Bio
Wang L,Zhang D,Ren Y,Guo S,Li J,Ma S,Yao M,Guan F
Sat Jan 01 00:00:00 EST 2022
Ameliorative effect of Gastrodia elata Blume extracts on depression in zebrafish and cellular models through modulating reticulon 4 receptors and apoptosis.
Journal of ethnopharmacology
Wang R,Ren Q,Gao D,Paudel YN,Li X,Wang L,Zhang P,Wang B,Shang X,Jin M
Tue May 10 00:00:00 EDT 2022
Ameliorative effect of Gastrodia elata Blume extracts on depression in zebrafish and cellular models through modulating reticulon 4 receptors and apoptosis.
Journal of ethnopharmacology
Wang R,Ren Q,Gao D,Paudel YN,Li X,Wang L,Zhang P,Wang B,Shang X,Jin M
Tue May 10 00:00:00 EDT 2022
TDAG51-Deficiency Podocytes are Protected from High-Glucose-Induced Damage Through Nrf2 Activation via the AKT-GSK-3β Pathway.
Inflammation
Liu C,Li Y,Wang X
Mon Aug 01 00:00:00 EDT 2022
Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage.
Cell death & disease
Lv Q,Han X,Ni J,Ma Q,Dai R,Liu J,Liu J,Zhai Y,Shen Q,Sun L,Liu H,Rao J,Xu H
Thu Oct 13 00:00:00 EDT 2022
A Second Near-Infrared Ru(II) Polypyridyl Complex for Synergistic Chemo-Photothermal Therapy.
Journal of medicinal chemistry
Liu Y,Li Q,Gu M,Lu D,Xiong X,Zhang Z,Pan Y,Liao Y,Ding Q,Gong W,Chen DS,Guan M,Wu J,Tian Z,Deng H,Gu L,Hong X,Xiao Y
Thu Feb 10 00:00:00 EST 2022
6-Shogaol Inhibits Oxidative Stress-Induced Rat Vascular Smooth Muscle Cell Apoptosis by Regulating OXR1-p53 Axis.
Frontiers in molecular biosciences
Liu J,Li B,Li W,Pan T,Diao Y,Wang F
Thu Nov 02 00:00:00 EDT 2023
Notch4 mediates vascular remodeling via ERK/JNK/P38 MAPK signaling pathways in hypoxic pulmonary hypertension.
Respiratory research
Guo M,Zhang M,Cao X,Fang X,Li K,Qin L,He Y,Zhao J,Xu Y,Liu X,Li X
Tue Jan 11 00:00:00 EST 2022
Circ_0078607 inhibits the progression of ovarian cancer via regulating the miR-32-5p/SIK1 network.
Journal of ovarian research
Jin Y,Wang H
Tue Jan 04 00:00:00 EST 2022
Regulation of the sensitivity of hepatocarcinoma cells by ORMDL3, to sorafenib by autophagy.
Medical oncology (Northwood, London, England)
Sun Y,Guan X,Zhang T,Li Y,Shi H,Chitakunye AT,Hong H,Zhang S,Zhu Q,Cai L
Tue Aug 16 00:00:00 EDT 2022
Assembly of Celastrol to Zeolitic Imidazolate Framework-8 by Coordination as a Novel Drug Delivery Strategy for Cancer Therapy.
Pharmaceuticals (Basel, Switzerland)
Wang N,Li Y,He F,Liu S,Liu Y,Peng J,Liu J,Yu C,Wang S
Mon Aug 29 00:00:00 EDT 2022
Polygonatum cyrtonema Hua Polysaccharides Protect BV2 Microglia Relief Oxidative Stress and Ferroptosis by Regulating NRF2/HO-1 Pathway.
Molecules (Basel, Switzerland)
Li J,Wang X,Zhou R,Cheng F,Tang X,Lao J,Xu L,He W,Wan D,Zeng H,Zhang S
Thu Oct 20 00:00:00 EDT 2022
MicroRNA profiling reveals miR-145-5p inhibits goat myoblast differentiation by targeting the coding domain sequence of USP13.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang Z,Deng K,Kang Z,Wang F,Fan Y
Fri Jul 01 00:00:00 EDT 2022
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
Journal of cellular and molecular medicine
Tai H,Tong YJ,Yu R,Yu Y,Yao SC,Li LB,Liu Y,Cui XZ,Kuang JS,Meng XS,Jiang XL
Wed Jun 01 00:00:00 EDT 2022
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
Journal of cellular and molecular medicine
Tai H,Tong YJ,Yu R,Yu Y,Yao SC,Li LB,Liu Y,Cui XZ,Kuang JS,Meng XS,Jiang XL
Wed Jun 01 00:00:00 EDT 2022
Feasibility of Catalpol Intranasal Administration and Its Protective Effect on Acute Cerebral Ischemia in Rats via Anti-Oxidative and Anti-Apoptotic Mechanisms.
Drug design, development and therapy
Wang J,Zhang Y,Zhang M,Sun S,Zhong Y,Han L,Xu Y,Wan D,Zhang J,Zhu H
Mon Mar 28 00:00:00 EDT 2022
Corilagin alleviates intestinal ischemia/reperfusion-induced intestinal and lung injury in mice via inhibiting NLRP3 inflammasome activation and pyroptosis.
Frontiers in pharmacology
Li W,Yang K,Li B,Wang Y,Liu J,Chen D,Diao Y
Wed Dec 21 00:00:00 EST 2022
microRNA-486-5p is implicated in the cisplatin-induced apoptosis and acute inflammation response of renal tubular epithelial cells by targeting HAT1.
Journal of biochemical and molecular toxicology
Lin FY,Han ST,Yu WM,Rao T,Ruan Y,Yuan R,Li HY,Ning JZ,Xia YQ,Xie JN,Qi YC,Zhou XJ,Cheng F
Wed Jun 01 00:00:00 EDT 2022
Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment.
European journal of medicinal chemistry
Liang JJ,Yu WL,Yang L,Xie BH,Qin KM,Yin YP,Yan JJ,Gong S,Liu TY,Zhou HB,Hong K
Sat Feb 05 00:00:00 EST 2022
Complement C1q binding protein regulates T cells' mitochondrial fitness to affect their survival, proliferation, and anti-tumor immune function.
Cancer science
Tian H,Wang G,Wang Q,Zhang B,Jiang G,Li H,Chai D,Fang L,Wang M,Zheng J
Tue Mar 01 00:00:00 EST 2022
Hyaluronic Acid Oligosaccharide Derivatives Alleviate Lipopolysaccharide-Induced Inflammation in ATDC5 Cells by Multiple Mechanisms.
Molecules (Basel, Switzerland)
Huang H,Ding X,Xing D,Lin J,Li Z,Lin J
Wed Aug 31 00:00:00 EDT 2022
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
Experimental neurology
Liu N,Li Y,Yang Y,Shu L,Liu Y,Wu Y,Sun D,Kang Z,Zhang Y,Ni D,Wei Z,Li S,Yang M,Wang Y,Sun J,Yang X
Tue Nov 01 00:00:00 EDT 2022
Inhibition of the miR-193b-3p protects against oxidized low-density lipoprotein-induced HUVECs injury by upregulating ALDH2.
Cell biology international
Bai Y,Wang M,Yang Y,Liu X,Chen Q,Guo Z
Tue Feb 01 00:00:00 EST 2022
Hepatic Ischemia-reperfusion Injury in Mice was Alleviated by Rac1 Inhibition - More Than Just ROS-inhibition.
Journal of clinical and translational hepatology
Sha Z,Yang Y,Liu R,Bao H,Song S,Dong J,Guo M,Zhao Y,Liu H,Ding G
Mon Feb 28 00:00:00 EST 2022
Shikonin induces apoptosis and autophagy via downregulation of pyrroline-5-carboxylate reductase1 in hepatocellular carcinoma cells.
Bioengineered
Zhang J,Shang L,Jiang W,Wu W
Tue Mar 01 00:00:00 EST 2022
Inhibition of calpain reduces cell apoptosis by suppressing mitochondrial fission in acute viral myocarditis.
Cell biology and toxicology
Shi H,Yu Y,Liu X,Yu Y,Li M,Wang Y,Zou Y,Chen R,Ge J
Wed Jun 01 00:00:00 EDT 2022
Cotargeting of Bcl-2 and Mcl-1 shows promising antileukemic activity against AML cells including those with acquired cytarabine resistance.
Experimental hematology
Liu F,Zhao Q,Su Y,Lv J,Gai Y,Liu S,Lin H,Wang Y,Wang G
Sat Jan 01 00:00:00 EST 2022
Cyclometalated iridium(III) dithioformic acid complexes as mitochondria-targeted imaging and anticancer agents.
Journal of inorganic biochemistry
Wu Y,Liu J,Shao M,Zhang P,Song S,Yang G,Liu X,Liu Z
Mon Aug 01 00:00:00 EDT 2022
Inhibition of the proliferation, invasion, migration, and epithelial-mesenchymal transition of prostate cancer cells through the action of ATP1A2 on the TGF-β/Smad pathway.
Translational andrology and urology
Zhang B,Zhu Z,Zhang X,Li F,Ding A
Sat Jan 01 00:00:00 EST 2022
Investigation into Antiepileptic Effect of Ganoderic Acid A and Its Mechanism in Seizure Rats Induced by Pentylenetetrazole.
BioMed research international
Pang W,Lu S,Zheng R,Li X,Yang S,Feng Y,Wang S,Guo J,Zhou S
Tue Sep 13 00:00:00 EDT 2022
Investigation into Antiepileptic Effect of Ganoderic Acid A and Its Mechanism in Seizure Rats Induced by Pentylenetetrazole.
BioMed research international
Pang W,Lu S,Zheng R,Li X,Yang S,Feng Y,Wang S,Guo J,Zhou S
Tue Sep 13 00:00:00 EDT 2022
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
Experimental cell research
Lan B,Zhao H,He Y,Zhao Z,Wang N,Gao Y
Tue Nov 15 00:00:00 EST 2022
Naringin alleviates acetaminophen-induced acute liver injury by activating Nrf2 via CHAC2 upregulation.
Environmental toxicology
Zhai X,Dai T,Chi Z,Zhao Z,Wu G,Yang S,Dong D
Wed Jun 01 00:00:00 EDT 2022
Effects of transforming growth factor beta-activated kinase 1 (TAK1) on apoptosis of HK-2 cells in the high glucose environment.
Bioengineered
Wang Y,Zhao L,Qiu D,Shi Y,Duan H
Tue Mar 01 00:00:00 EST 2022
Exosomal microRNA-551b-3p from bone marrow-derived mesenchymal stromal cells inhibits breast cancer progression via regulating TRIM31/Akt signaling.
Human cell
Yang Z,Xu B,Wu S,Yang W,Luo R,Geng S,Xin Z,Jin W,Shen X,Gu X,Zhang H,Wang H
Tue Nov 01 00:00:00 EDT 2022
Integrated Strategies of Diverse Feature Selection Methods Identify Aging-Based Reliable Gene Signatures for Ischemic Cardiomyopathy.
Frontiers in molecular biosciences
Song H,Chen S,Zhang T,Huang X,Zhang Q,Li C,Chen C,Chen S,Liu D,Wang J,Tu Y,Wu Y,Liu Y
Sat Mar 19 00:00:00 EDT 2022
Expressions and significances of CTSL, the target of COVID-19 on GBM.
Journal of cancer research and clinical oncology
Dong Q,Li Q,Duan L,Wang H,Yan Y,Yin H,Niu L,Zhang H,Wang B,Yuan G,Pan Y
Tue Mar 01 00:00:00 EST 2022
TRIM59 promotes osteosarcoma progression via activation of STAT3.
Human cell
Xu G,Ma Z,Yang F,Bai Y,Li J,Luo W,Zhong J
Sat Jan 01 00:00:00 EST 2022
MiR-181c suppresses triple-negative breast cancer tumorigenesis by targeting MAP4K4.
Pathology, research and practice
Xie D,Li S,Wu T,Wang X,Fang L
Tue Feb 01 00:00:00 EST 2022
QiShenYiQi pill for myocardial collagen metabolism and apoptosis in rats of autoimmune cardiomyopathy.
Pharmaceutical biology
Lv S,Zhang W,Yuan P,Lu C,Dong J,Zhang J
Thu Dec 01 00:00:00 EST 2022
Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.
Inflammation
Zeng L,He J,Liu C,Zhang F,Zhang Z,Chen H,Wang Q,Ding X,Luo H
Fri Apr 01 00:00:00 EDT 2022
Cinnamomi Ramulus inhibits the growth of colon cancer cells via Akt/ERK signaling pathways.
Chinese medicine
Pan B,Xia Y,Gao Z,Zhao G,Wang L,Fang S,Liu L,Yan S
Wed Mar 09 00:00:00 EST 2022
Knockdown of TTC9 inhibits the proliferation, migration and invasion, but induces the apoptosis of lung adenocarcinoma cells.
Heliyon
Huang X,Jiang L,Wen Z,Yuan M,Zhong Y
Tue Nov 01 00:00:00 EDT 2022
Revealing the mechanism of Jiegeng decoction attenuates bleomycin-induced pulmonary fibrosis via PI3K/Akt signaling pathway based on lipidomics and transcriptomics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Xu Y,Wang X,Han D,Wang J,Luo Z,Jin T,Shi C,Zhou X,Lin L,Shan J
Wed Jul 20 00:00:00 EDT 2022
Exosomes-derived miR-125-5p from cartilage endplate stem cells regulates autophagy and ECM metabolism in nucleus pulposus by targeting SUV38H1.
Experimental cell research
Chen D,Jiang X
Sun May 01 00:00:00 EDT 2022
BCATc inhibitor 2 ameliorated mitochondrial dysfunction and apoptosis in oleic acid-induced non-alcoholic fatty liver disease model.
Frontiers in pharmacology
Lu Z,Sun GF,Pan XA,Qu XH,Yang P,Chen ZP,Han XJ,Wang T
Fri Nov 18 00:00:00 EST 2022
Therapeutic targeting m6A-guided miR-146a-5p signaling contributes to the melittin-induced selective suppression of bladder cancer.
Cancer letters
Yan R,Dai W,Wu R,Huang H,Shu M
Sat May 28 00:00:00 EDT 2022
Fecal Microbiota Transplantation Alleviated Cerebral Ischemia Reperfusion Injury in Obese Rats.
The Tohoku journal of experimental medicine
Xie T,Yang R,Zhang X,Shen X,Yu L,Liao J,Bao T,Fang Q
Wed Dec 14 00:00:00 EST 2022
Suffruticosol C-Mediated Autophagy and Cell Cycle Arrest via Inhibition of mTORC1 Signaling.
Nutrients
Qin S,Geng H,Wang G,Chen L,Xia C,Yao J,Bai Z,Deng L
Thu Nov 24 00:00:00 EST 2022
Hydrogen sulfide against preeclampsia exposure-induced oxidative mitochondrial damage in HTR-8/SVneo cells.
Frontiers in cardiovascular medicine
Wang X,Yu S,Jian Y,Pan H,Guo J,Wu J,Guo W
Fri Nov 18 00:00:00 EST 2022
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Ecotoxicology and environmental safety
Zeng HF,Xu J,Wang XL,Li SJ,Han ZY
Fri Apr 15 00:00:00 EDT 2022
The lncRNA KIF9-AS1 Accelerates Hepatocellular Carcinoma Growth by Recruiting DNMT1 to Promote RAI2 DNA Methylation.
Journal of oncology
Yu Y,Lu X,Yan Y,Wang Y,Meng J,Tian S,Mu J
Tue Oct 25 00:00:00 EDT 2022
Effects of regenerative peripheral nerve interface on dorsal root ganglia neurons following peripheral axotomy.
Frontiers in neuroscience
Wang Z,Zhang D,Yi XZ,Zhao Y,Yu A
Wed Sep 28 00:00:00 EDT 2022
Carboxymethyl Chitosan Modified Oxymatrine Liposomes for the Alleviation of Emphysema in Mice via Pulmonary Administration.
Molecules (Basel, Switzerland)
Peng J,Cai Z,Wang Q,Zhou J,Xu J,Pan D,Chen T,Zhang G,Tao L,Chen Y,Shen X
Sat Jun 04 00:00:00 EDT 2022
Chelerythrine-Induced Apoptotic Cell Death in HepG2 Cells Involves the Inhibition of Akt Pathway and the Activation of Oxidative Stress and Mitochondrial Apoptotic Pathway.
Antioxidants (Basel, Switzerland)
Lin Y,Zhang Q,Xie B,Jiang H,Shen J,Tang S,Dai C
Sun Sep 18 00:00:00 EDT 2022
Inhibition of Circ-Snrk ameliorates apoptosis and inflammation in acute kidney injury by regulating the MAPK pathway.
Renal failure
Meng F,Chen Q,Gu S,Cui R,Ma Q,Cao R,Zhao M
Thu Dec 01 00:00:00 EST 2022
Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.
Cell death & disease
Yi L,Shang XJ,Lv L,Wang Y,Zhang J,Quan C,Shi Y,Liu Y,Zhang L
Sat Nov 05 00:00:00 EDT 2022
A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responses.
Nature communications
Wang X,Liu Y,Xue C,Hu Y,Zhao Y,Cai K,Li M,Luo Z
Wed Sep 28 00:00:00 EDT 2022
RhFGF21 Protects Epidermal Cells against UVB-Induced Apoptosis through Activating AMPK-Mediated Autophagy.
International journal of molecular sciences
Zhao Y,Lin J,Li J,Bwalya C,Xu Y,Niu Y,Zhang Y,Wu J,Xu Y,Chen J,Ye S,Lin L
Tue Oct 18 00:00:00 EDT 2022
Comprehensive analysis of hypoxia-related genes for prognosis value, immune status, and therapy in osteosarcoma patients.
Frontiers in pharmacology
Han T,Wu Z,Zhang Z,Liang J,Xia C,Yan H
Wed Feb 01 00:00:00 EST 2023
MicroRNA-124 modulates neuroinflammation in acute methanol poisoning rats via targeting Krüppel-like factor-6.
Bioengineered
Zhou S,Li J,Zhang X,Xiong W
Sun May 01 00:00:00 EDT 2022
Dezocine inhibits cell proliferation, migration, and invasion by targeting CRABP2 in ovarian cancer.
Open medicine (Warsaw, Poland)
Zhang C,Pan R,Ma S,Xu S,Wang B
Tue Jan 03 00:00:00 EST 2023
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhou Y,Lu Q
Thu Sep 01 00:00:00 EDT 2022
Cardiomyocyte IL-1R2 protects heart from ischemia/reperfusion injury by attenuating IL-17RA-mediated cardiomyocyte apoptosis.
Cell death & disease
Lin J,Li Q,Jin T,Wang J,Gong Y,Lv Q,Wang M,Chen J,Shang M,Zhao Y,Fu G
Thu Jan 27 00:00:00 EST 2022
Mechanism of HSP90 Inhibitor in the Treatment of DSS-induced Colitis in Mice by Inhibiting MAPK Pathway and Synergistic Effect of Compound Sophora Decoction.
Current pharmaceutical design
Yuan Y,Wu H,Shuai B,Liu C,Zhu F,Gao F,Wei C,Fan H
Fri Jan 06 00:00:00 EST 2023
Manganese Mitigates Heat Stress-Induced Apoptosis by Alleviating Endoplasmic Reticulum Stress and Activating the NRF2/SOD2 Pathway in Primary Chick Embryonic Myocardial Cells.
Biological trace element research
Qin S,Wang R,Tang D,Qin S,Guo Y,Shi Z
Sun May 01 00:00:00 EDT 2022
BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53.
Journal of Cancer
Luo Y,Wang X,Niu W,Zhou Y,Li M,Ma J,Yang J,Fan S,Zeng Z,Xiong W,Li X,Li G,Xiao J,Zhou M
Tue Apr 05 00:00:00 EDT 2022
Para‑hydroxybenzaldehyde against transient focal cerebral ischemia in rats via mitochondrial preservation.
Experimental and therapeutic medicine
Xiao T,Yang L,Chen P,Duan X
Thu Dec 01 00:00:00 EST 2022
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
BMC musculoskeletal disorders
Xu P,Chang J,Ma G,Liao F,Xu T,Wu Y,Yin Z
Sat Nov 26 00:00:00 EST 2022
Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.
Folia histochemica et cytobiologica
Xiong W,Huang XL,Li CY,Wang XL,Lan HW,Wang TT,Chen ZL,Yang QP,Hu AL,Xia YF,Zhu FR,Zhou ZZ
Mon Jan 02 00:00:00 EST 2023
WY-14643 attenuates lipid deposition via activation of the PPARα/CPT1A axis by targeting Gly335 to inhibit cell proliferation and migration in ccRCC.
Lipids in health and disease
Wang R,Zhao J,Jin J,Tian Y,Lan L,Wang X,Zhu L,Wang J
Wed Nov 16 00:00:00 EST 2022
Anti-aging effect of phlorizin on D-galactose-induced aging in mice through antioxidant and anti-inflammatory activity, prevention of apoptosis, and regulation of the gut microbiota.
Experimental gerontology
Chen H,Dong L,Chen X,Ding C,Hao M,Peng X,Zhang Y,Zhu H,Liu W
Wed Jun 15 00:00:00 EDT 2022
The Ameliorative Effect of JNK Inhibitor D-JNKI-1 on Neomycin-Induced Apoptosis in HEI-OC1 Cells.
Frontiers in molecular neuroscience
Zhao J,Liu H,Huang Z,Yang R,Gong L
Sat Apr 02 00:00:00 EDT 2022
Activation of LRP1 Ameliorates Cerebral Ischemia/Reperfusion Injury and Cognitive Decline by Suppressing Neuroinflammation and Oxidative Stress through TXNIP/NLRP3 Signaling Pathway in Mice.
Oxidative medicine and cellular longevity
Yang CJ,Li X,Feng XQ,Chen Y,Feng JG,Jia J,Wei JC,Zhou J
Tue Aug 30 00:00:00 EDT 2022
Blocking REDD1/TXNIP Complex Ameliorates HG-Induced Renal Tubular Epithelial Cell Apoptosis and EMT through Repressing Oxidative Stress.
International journal of endocrinology
Mu L,Chen N,Chen Y,Yang Z,Zhou H,Song S,Shi Y
Tue Oct 04 00:00:00 EDT 2022
Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps.
Frontiers in pharmacology
Dong C,Chen Z,Zhu L,Bsoul N,Wu H,Jiang J,Chen X,Lai Y,Yu G,Gu Y,Guo X,Gao W
Sat Mar 05 00:00:00 EST 2022
Pre-ischemic exercise prevents inflammation and apoptosis by inhibiting MAPK pathway in ischemic stroke.
Translational neuroscience
Gao ZK,Shen XY,Han Y,Guo YS,Li K,Bi X
Sat Jan 01 00:00:00 EST 2022
Curculigoside mitigates hepatic ischemia/reperfusion-induced oxidative stress, inflammation, and apoptosis via activation of the Nrf-2/HO-1 pathway.
Human & experimental toxicology
Du P,Zhang X,Luo K,Li Y,Fu C,Xiao J,Xiao Q
Mon Apr 04 00:00:00 EDT 2022
Long noncoding RNA H19 mediates neural stem/progenitor cells proliferation, differentiation and apoptosis through the p53 signaling pathway after ischemic stroke.
Biochemical and biophysical research communications
Gan L,Liao S,Tong Y,Li W,Peng W,Deng S
Tue Mar 15 00:00:00 EDT 2022
The neuroprotective effects of phosphocreatine on amyloid beta 25-35-induced differentiated neuronal cell death through inhibition of AKT/GSK-3β /Tau/APP/CDK5 pathways in vivo and vitro.
Free radical biology & medicine
Ai J,Wang H,Chu P,Shopit A,Niu M,Ahmad N,Tesfaldet T,Wang FH,Fang JN,Li X,Tang SJ,Han QJ,Han G,Peng J,Tang Z
Tue Feb 01 00:00:00 EST 2022
SCO-spondin-derived peptide NX210 rescues neurons from cerebral ischemia/reperfusion injury through modulating the Integrin-β1 mediated PI3K/Akt pathway.
International immunopharmacology
Yang L,Zhu J,Yang L,Gan Y,Hu D,Zhao J,Zhao Y
Sat Oct 01 00:00:00 EDT 2022
Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway.
Journal of ethnopharmacology
Wang T,Chen Z,Chen H,Yu X,Wang L,Liu X
Sun Apr 24 00:00:00 EDT 2022
Phenolic Acids from Fructus Chebulae Immaturus Alleviate Intestinal Ischemia-Reperfusion Injury in Mice through the PPARα/NF-κB Pathway.
Molecules (Basel, Switzerland)
Liu J,Li B,Liu J,Qiu F,Diao Y,Lei Y,Liu J,Zhang W
Tue Aug 16 00:00:00 EDT 2022
Staphylococcus aureus Induces Goat Endometrial Epithelial Cells Apoptosis via the Autophagy and Endoplasmic Reticulum Stress Pathway.
Animals : an open access journal from MDPI
Yi Y,Gao K,Zhang R,Lin P,Wang A,Jin Y
Fri Mar 11 00:00:00 EST 2022
miR-29b-3p inhibits 22Rv1 prostate cancer cell proliferation through the YWHAE/BCL-2 regulatory axis.
Oncology letters
Zhao J,Ma X,Xu H
Mon Aug 01 00:00:00 EDT 2022
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42) inhibits cell proliferation and induces apoptosis via inhibiting ALK and its downstream pathways in Karpas299 cells.
Toxicology and applied pharmacology
Chang X,Wang J,Bian J,Liu Z,Guo M,Li Z,Wu Y,Zhai X,Zuo D
Thu Sep 01 00:00:00 EDT 2022
Hax-1 Regulates Radiation-Induced Mitochondrial-Dependent Apoptosis of Uveal Melanoma Cells through PI3K/AKT/eNOS Pathway.
Journal of oncology
Wang S,Tan J,Chen L,Wang J
Sat Jul 16 00:00:00 EDT 2022
ABCA12 Promotes Proliferation and Migration and Inhibits Apoptosis of Pancreatic Cancer Cells Through the AKT Signaling Pathway.
Frontiers in genetics
Zheng S,Liu D,Wang F,Jin Y,Zhao S,Sun S,Wang S
Sat Jul 16 00:00:00 EDT 2022
Curcumin Inhibits Hyperandrogen-Induced IRE1α-XBP1 Pathway Activation by Activating the PI3K/AKT Signaling in Ovarian Granulosa Cells of PCOS Model Rats.
Oxidative medicine and cellular longevity
Zhang Y,Wang L,Weng Y,Wang D,Wang R,Wang H,Wang L,Shen S,Wang H,Li Y,Wang Y
Wed Sep 07 00:00:00 EDT 2022
Expression pattern of alkB homolog 5 in goat testis and its role in spermatogonial stem cells.
Cell and tissue research
Liu Z,Cai Y,Deng M,Li D,Leng Q,Shi L,Tang Y,Wang F,Wan Y
Sat Jan 01 00:00:00 EST 2022
C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α.
Theranostics
Zheng W,Wang K,Wu Y,Yan G,Zhang C,Li Z,Wang L,Chen S
Thu Dec 08 00:00:00 EST 2022
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK.
Oxidative medicine and cellular longevity
Chen C,Chen Y,Liu T,Song D,Ma D,Cheng O
Tue May 10 00:00:00 EDT 2022
Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway.
Oxidative medicine and cellular longevity
Zhang YL,Li PB,Han X,Zhang B,Li HH
Tue May 24 00:00:00 EDT 2022
Mild hypothermia ameliorates hepatic ischemia reperfusion injury by inducing RBM3 expression.
Apoptosis : an international journal on programmed cell death
Xiao Q,Liu Y,Zhang X,Liu Z,Xiao J,Ye Q,Fu B
Thu Dec 01 00:00:00 EST 2022
FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer's Disease: Evidence from Single-Cell Transcriptomic Analysis.
Pharmaceuticals (Basel, Switzerland)
Dang Y,He Q,Yang S,Sun H,Liu Y,Li W,Tang Y,Zheng Y,Wu T
Thu Sep 22 00:00:00 EDT 2022
Effect of ribose-glycated BSA on histone demethylation.
Frontiers in genetics
Xi M,Zhang L,Wei Y,Li T,Qu M,Hua Q,He R,Liu Y
Tue Oct 25 00:00:00 EDT 2022
The Novel lncRNA RP9P Promotes Colorectal Cancer Progression by Modulating miR-133a-3p/FOXQ1 Axis.
Frontiers in oncology
Jin Z,Liu B,Lin B,Yang R,Wu C,Xue W,Zou X,Qian J
Sun Nov 05 00:00:00 EDT 2023
The Novel lncRNA RP9P Promotes Colorectal Cancer Progression by Modulating miR-133a-3p/FOXQ1 Axis.
Frontiers in oncology
Jin Z,Liu B,Lin B,Yang R,Wu C,Xue W,Zou X,Qian J
Sun Nov 05 00:00:00 EDT 2023
ZFP36 protects against oxygen-glucose deprivation/reoxygenation-induced mitochondrial fragmentation and neuronal apoptosis through inhibiting NOX4-DRP1 pathway.
Brain research bulletin
Guo H,Jiang Y,Gu Z,Ren L,Zhu C,Yu S,Wei R
Tue Feb 01 00:00:00 EST 2022
Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress in T2DM rats.
Food & function
Liu Y,Huang H,Xu Z,Xue Y,Zhang D,Zhang Y,Li W,Li X
Mon Mar 07 00:00:00 EST 2022
Alfalfa saponins inhibit oxidative stress-induced cell apoptosis through the MAPK signaling pathway.
Redox report : communications in free radical research
Cui Y,Li F,Zhu X,Xu J,Muhammad A,Chen Y,Li D,Liu B,Wang C,Wang Z,Ma S,Liu X,Shi Y
Thu Dec 01 00:00:00 EST 2022
Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.
Virulence
Jie W,Rui-Fen Z,Zhong-Xiang H,Yan W,Wei-Na L,Yong-Ping M,Jing S,Jing-Yi C,Wan-Hong L,Xiao-Hua H,Zhi L,Yan S
Thu Dec 01 00:00:00 EST 2022
Protective Effect of Manganese on Apoptosis and Mitochondrial Function of Heat-Stressed Primary Chick Embryonic Myocardial Cells.
Biological trace element research
Wang R,Shi Z,Li J,Tang D,Qin S,Guo Y
Sat Oct 01 00:00:00 EDT 2022
Oleoylethanolamide Alleviates Hepatic Ischemia-Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress-Associated Apoptosis.
PPAR research
Qi S,Yan Q,Wang Z,Liu D,Zhan M,Du J,Chen L
Fri Apr 01 00:00:00 EDT 2022
EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress.
Journal of oncology
Wu W,Gou H,Xiang B,Geng R,Dong J,Yang X,Chen D,Dai R,Chen L,Liu J
Sat Sep 24 00:00:00 EDT 2022
MiR-125b enhances doxorubicin-induced cardiotoxicity by suppressing the nucleus-cytoplasmic translocation of YAP via targeting STARD13.
Environmental toxicology
Jin X,Yu W,Ye P
Fri Apr 01 00:00:00 EDT 2022
β-Carotene Attenuates Apoptosis and Autophagy via PI3K/AKT/mTOR Signaling Pathway in Necrotizing Enterocolitis Model Cells IEC-6.
Evidence-based complementary and alternative medicine : eCAM
Xu G,Ma T,Zhou C,Zhao F,Peng K,Li B
Sat Jul 16 00:00:00 EDT 2022
Engeletin Alleviates the Inflammation and Apoptosis in Intervertebral Disc Degeneration via Inhibiting the NF-κB and MAPK Pathways.
Journal of inflammation research
Li B,Yang X,Zhang P,Guo J,Rong K,Wang X,Cao X,Zhou T,Zhao J
Sat Oct 15 00:00:00 EDT 2022
Protective Effect of Shenfu Injection on Vascular Endothelial Damage in a Porcine Model of Hemorrhagic Shock.
Chinese journal of integrative medicine
Zhang MQ,Zhang Q,Yuan W,Wu JY,Liang Y,Qin HJ,Li CS
Thu Sep 01 00:00:00 EDT 2022
Protective Effect of Shenfu Injection on Vascular Endothelial Damage in a Porcine Model of Hemorrhagic Shock.
Chinese journal of integrative medicine
Zhang MQ,Zhang Q,Yuan W,Wu JY,Liang Y,Qin HJ,Li CS
Thu Sep 01 00:00:00 EDT 2022
LincRNA-p21 Upregulates Nuclear Orphan Receptor Nr4a2 and Aggravates Myocardial Ischemia/Reperfusion Injury via Targeting MiR-466i-5p.
International heart journal
Zhai X,Liu R,Li J,Wang F,Liu L,Wei S,Bian Y,Pang J,Xue M,Qin D,Wang S,Xu T,Xu F,Cao S,Yuan Q,Chen Y
Tue Oct 04 00:00:00 EDT 2022
Yangjing Zhongyu decoction facilitates mitochondrial activity, estrogenesis, and energy metabolism in H2O2-induced human granulosa cell line KGN.
Journal of ethnopharmacology
Liu J,Shi D,Ma Q,Zhao P
Thu Sep 15 00:00:00 EDT 2022
Polygonum cuspidatum inhibits the growth of osteosarcoma cells via impeding Akt/ERK/EGFR signaling pathways.
Bioengineered
Zhao J,Pan B,Zhou X,Wu C,Hao F,Zhang J,Liu L
Tue Feb 01 00:00:00 EST 2022
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
Placenta
Chen X,Song QL,Ji R,Wang JY,Li ZH,Guo D,Yin TL,Wang SJ,Yang J
Tue Feb 01 00:00:00 EST 2022
Reactive Oxygen Species- and Cell-Free DNA-Scavenging Mn3O4 Nanozymes for Acute Kidney Injury Therapy.
ACS applied materials & interfaces
Meng L,Feng J,Gao J,Zhang Y,Mo W,Zhao X,Wei H,Guo H
Wed Nov 16 00:00:00 EST 2022
Keloid Patient Plasma-Derived Exosomal hsa_circ_0020792 Promotes Normal Skin Fibroblasts Proliferation, Migration, and Fibrogenesis via Modulating miR-193a-5p and Activating TGF-β1/Smad2/3 Signaling.
Drug design, development and therapy
Hu H,Mao G,Zheng J,Guo F
Fri Dec 23 00:00:00 EST 2022
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
Cells
He D,Liu Y,Li J,Wang H,Ye B,He Y,Li Z,Gao X,Fu S,Liu D
Mon Sep 19 00:00:00 EDT 2022
Pharmacological Inhibition of Endogenous Hydrogen Sulfide Attenuates Breast Cancer Progression.
Molecules (Basel, Switzerland)
Khan NH,Wang D,Wang W,Shahid M,Khattak S,Ngowi EE,Sarfraz M,Ji XY,Zhang CY,Wu DD
Thu Jun 23 00:00:00 EDT 2022
Design, synthesis, and in vitro protective effect evaluation of α-carboline derivatives against H2O2-induced cardiomyocyte injury.
European journal of medicinal chemistry
Zhang RH,Yang D,Liao XM,Zhang H,Chen GQ,Zhang WL,Wang YC,Wang C,Liao SG,Zhou M,Wang YL,Li YJ
Fri Aug 05 00:00:00 EDT 2022
Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control.
Food & function
Zhong Y,Liu J,Sun D,Guo T,Yao Y,Xia X,Shi C,Peng X
Mon Mar 21 00:00:00 EDT 2022
Matrix metalloproteinase-7 promotes chronic kidney disease progression via the induction of inflammasomes and the suppression of autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zheng CM,Lu KC,Chen YJ,Li CY,Lee YH,Chiu HW
Sat Oct 01 00:00:00 EDT 2022
Thrombus Inhibition and Neuroprotection for Ischemic Stroke Treatment through Platelet Regulation and ROS Scavenging.
ChemMedChem
Ye H,Ma Z,Liu L,Zhang T,Han Q,Xiang Z,Xia Y,Ke Y,Guan X,Shi Q,Ataullakhanov FI,Panteleev M
Fri Dec 16 00:00:00 EST 2022
Gamma-oryzanol protects human liver cell (L02) from hydrogen peroxide-induced oxidative damage through regulation of the MAPK/Nrf2 signaling pathways.
Journal of food biochemistry
Ma Y,Xiang S,Jiang W,Kong L,Tan Z,Liang Z,Yuan Z,Yi J,Zhu L
Fri Jul 01 00:00:00 EDT 2022
Smad7 Is Highly Expressed in Human Degenerative Discs and Participates in IL-1β-Induced Apoptosis of Rat AF Cells via the Mitochondria Pathway.
Oxidative medicine and cellular longevity
Li B,Lu ZY,Jiang SD,Jiang LS,Zheng XF
Fri Jul 08 00:00:00 EDT 2022
N-acetylserotonin protects PC12 cells from hydrogen peroxide induced damage through ROS mediated PI3K / AKT pathway.
Cell cycle (Georgetown, Tex.)
Kang J,Wang Y,Guo X,He X,Liu W,Chen H,Wang Z,Lin A,Kang X
Tue Nov 01 00:00:00 EDT 2022
Chlorine disinfection elevates the toxicity of polystyrene microplastics to human cells by inducing mitochondria-dependent apoptosis.
Journal of hazardous materials
Qin J,Xia PF,Yuan XZ,Wang SG
Sat Mar 05 00:00:00 EST 2022
Network pharmacology analysis uncovers the effect on apoptotic pathway by Bu-Fei formula for COPD treatment.
Journal of ethnopharmacology
Zhang LX,Tian YG,Zhao P,Feng SX,Han XX,Li JS
Tue May 10 00:00:00 EDT 2022
Nephrotoxicity evaluation of 3-monochloropropane-1,2-diol exposure in Sprague-Dawley rats using data-independent acquisition-based quantitative proteomics analysis.
Toxicology letters
Jin C,Min F,Zhong Y,Sun D,Luo R,Liu Q,Peng X
Tue Mar 01 00:00:00 EST 2022
S100A8 regulates autophagy-dependent ferroptosis in microglia after experimental subarachnoid hemorrhage.
Experimental neurology
Tao Q,Qiu X,Li C,Zhou J,Gu L,Zhang L,Pang J,Zhang L,Yin S,Jiang Y,Peng J
Tue Nov 01 00:00:00 EDT 2022
SerpinA3N attenuates ischemic stroke injury by reducing apoptosis and neuroinflammation.
CNS neuroscience & therapeutics
Zhang Y,Chen Q,Chen D,Zhao W,Wang H,Yang M,Xiang Z,Yuan H
Fri Apr 01 00:00:00 EDT 2022
Blocking protease-activated receptor 4 alleviates liver injury induced by brain death.
Biochemical and biophysical research communications
Fang H,Yuan Z,Zhu Y,Tang H,Pang C,Li J,Shi J,Guo W,Zhang S
Sat Mar 05 00:00:00 EST 2022
Autophagy and apoptosis mediated nano-copper-induced testicular damage.
Ecotoxicology and environmental safety
Chen H,Wang Y,Luo J,Kang M,Hou J,Tang R,Zhao L,Shi F,Ye G,He X,Cui H,Guo H,Li Y,Tang H
Sat Jan 01 00:00:00 EST 2022
Dissection of Targeting Molecular Mechanisms of Aristolochic Acid-induced Nephrotoxicity via a Combined Deconvolution Strategy of Chemoproteomics and Metabolomics.
International journal of biological sciences
Zhang Q,Luo P,Chen J,Yang C,Xia F,Zhang J,Tang H,Liu D,Gu L,Shi Q,He X,Yang T,Wang J
Fri Apr 15 00:00:00 EDT 2022
Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3-mediated N6-methyladenosine modification of ICAM2 mRNA in fibroblast-like synoviocytes.
Clinical and translational medicine
Chen J,Lin X,He J,Liu D,He L,Zhang M,Luan H,Hu Y,Tao C,Wang Q
Thu Dec 01 00:00:00 EST 2022
Mechanical stretch aggravates vascular smooth muscle cell apoptosis and vascular remodeling by downregulating EZH2.
The international journal of biochemistry & cell biology
Zhong HY,Yuan C,Liu XL,Wang QQ,Li X,Zhao YC,Li X,Liu DD,Zheng TF,Zhang M
Sat Oct 01 00:00:00 EDT 2022
Nonylphenol inhibited HIF-1alpha regulated aerobic glycolysis and induced ROS mediated apoptosis in rat Sertoli cells.
Ecotoxicology and environmental safety
Jiang Q,Di Q,Shan D,Xu Q
Mon Aug 01 00:00:00 EDT 2022
Inactivation of Yes-Associated Protein Mediates Trophoblast Dysfunction: A New Mechanism of Pregnancy Loss Associated with Anti-Phospholipid Antibodies?
Biomedicines
Huang Z,Tang Z,Guan H,Leung W,Wang L,Xia H,Zhang W
Mon Dec 19 00:00:00 EST 2022
Sevoflurane induced neurotoxicity in neonatal mice links to a GSK3β/Drp1-dependent mitochondrial fission and apoptosis.
Free radical biology & medicine
Liu J,Li L,Xie P,Zhao X,Shi D,Zhang Y,Pan C,Li T
Tue Mar 01 00:00:00 EST 2022
Promotion of tumor progression induced by continuous low-dose administration of antineoplastic agent gemcitabine or gemcitabine combined with cisplatin.
Life sciences
Chen Y,Liu H,Zheng Q,Li H,You H,Feng Y,Feng W
Sat Oct 01 00:00:00 EDT 2022
Time series RNA-seq analysis identifies MAPK10 as a critical gene in diabetes mellitus-induced atrial fibrillation in mice.
Journal of molecular and cellular cardiology
Liu F,Deng Y,Zhao Y,Li Z,Gao J,Zhang Y,Yang X,Liu Y,Xia Y
Fri Jul 01 00:00:00 EDT 2022
Cytosolic p53 Inhibits Parkin-Mediated Mitophagy and Promotes Acute Liver Injury Induced by Heat Stroke.
Frontiers in immunology
Huang W,Xie W,Zhong H,Cai S,Huang Q,Liu Y,Zeng Z,Liu Y
Thu Jun 02 00:00:00 EDT 2022
RBM47 inhibits hepatocellular carcinoma progression by targeting UPF1 as a DNA/RNA regulator.
Cell death discovery
Guo T,You K,Chen X,Sun Y,Wu Y,Wu P,Jiang Y
Thu Jul 14 00:00:00 EDT 2022
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
The Journal of cell biology
Oshima Y,Cartier E,Boyman L,Verhoeven N,Polster BM,Huang W,Kane M,Lederer WJ,Karbowski M
Mon Jun 07 00:00:00 EDT 2021
Docosahexaenoic acid activates the Nrf2 signaling pathway to alleviate impairment of spleen cellular immunity in intrauterine growth restricted rat pups.
Saudi journal of biological sciences
Jiang W,Wan L,Chen P,Lu W
Wed Sep 01 00:00:00 EDT 2021
Suppressing TRAP1 sensitizes glioblastoma multiforme cells to temozolomide.
Experimental and therapeutic medicine
Wang N,Zhu P,Huang R,Sun L,Dong D,Gao Y
Mon Nov 01 00:00:00 EDT 2021
Overexpression of SHMT2 Predicts a Poor Prognosis and Promotes Tumor Cell Growth in Bladder Cancer.
Frontiers in genetics
Zhang P,Yang Q
Tue Jun 22 00:00:00 EDT 2021
Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.
FEBS open bio
Tian L,Wang S,Zhao L,Lu X,Zhu C,Gong H,Yang W
Sun Aug 01 00:00:00 EDT 2021
Riluzole-induced apoptosis in osteosarcoma is mediated through Yes-associated protein upon phosphorylation by c-Abl Kinase.
Scientific reports
Raghubir M,Azeem SM,Hasnat R,Rahman CN,Wong L,Yan S,Huang YQ,Zhagui R,Blyufer A,Tariq I,Tam C,Lhamo S,Cecilio L,Chowdhury Y,ChandThakuri S,Mahajan SS
Mon Oct 25 00:00:00 EDT 2021
Acupuncture Relieves Stress-Induced Depressive Behavior by Reducing Oxidative Stress and Neuroapoptosis in Rats.
Frontiers in behavioral neuroscience
Cheng WJ,Li P,Huang WY,Huang Y,Chen WJ,Chen YP,Shen JL,Chen JK,Long NS,Meng XJ
Sat Jan 22 00:00:00 EST 2022
Tissue-based metabolomics reveals metabolic biomarkers and potential therapeutic targets for esophageal squamous cell carcinoma.
Journal of pharmaceutical and biomedical analysis
Chen Z,Gao Y,Huang X,Yao Y,Chen K,Zeng S,Mao W
Thu Apr 15 00:00:00 EDT 2021
Tβ4 ameliorates oxidative damage and apoptosis through ERK/MAPK and 5-HT1A signaling pathway in Aβ insulted SH-SY5Y cells.
Life sciences
Zhang GH,Pare RB,Chin KL,Qian YH
Thu Nov 25 00:00:00 EST 2021
Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities.
Cell death discovery
Li P,Liu X,Zhao T,Li F,Wang Q,Zhang P,Hirayama R,Chen W,Jin X,Zheng X,Wang Z,Li Q
Tue Jul 20 00:00:00 EDT 2021
SIRT1 Deacetylates TET2 and Promotes Its Ubiquitination Degradation to Achieve Neuroprotection Against Parkinson's Disease.
Frontiers in neurology
Li X,Liu T,Wu TT,Feng Y,Peng SJ,Yin H,Wu YC
Tue May 04 00:00:00 EDT 2021
Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation.
PPAR research
Zhang J,Cheng P,Dai W,Ji J,Wu L,Feng J,Wu J,Yu Q,Li J,Guo C
Sat Feb 20 00:00:00 EST 2021
Morroniside protects OLN-93 cells against H2O2-induced injury through the PI3K/Akt pathway-mediated antioxidative stress and antiapoptotic activities.
Cell cycle (Georgetown, Tex.)
Li F,Song X,Xu J,Shi Y,Hu R,Ren Z,Qi Q,Lü H,Cheng X,Hu J
Thu Apr 01 00:00:00 EDT 2021
Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis.
Journal of cellular physiology
Mou J,Xu J,Wang Z,Wang C,Yang X,Wang X,Xue H,Wu M,Xu L
Mon Mar 01 00:00:00 EST 2021
8-Formylophiopogonanone B induces ROS-mediated apoptosis in nasopharyngeal carcinoma CNE-1 cells.
Toxicology research
Zhang YJ,Mu ZL,Deng P,Liang YD,Wu LC,Yang LL,Zhou Z,Yu ZP
Fri Oct 01 00:00:00 EDT 2021
Role of Notch pathway in effect of mono-2-ethylhexyl phthalate on the proliferation and cell cycle of SH-SY5Y cell.
Environmental toxicology
Zhang B,Li X,Zhang X,Ye J,Zhao W,Zhang M,Xing J,Qi W,Ye L
Wed Sep 01 00:00:00 EDT 2021
miR‑140‑5p alleviates mouse liver ischemia/reperfusion injury by targeting CAPN1.
Molecular medicine reports
Yu Q,Chen S,Tang H,Yang H,Zhang J,Shi X,Li J,Guo W,Zhang S
Wed Sep 01 00:00:00 EDT 2021
Low-dose repeated exposure to chemical surfactant impairs corneal epithelium: When personal cleaning products entering the eye.
Experimental eye research
Wu J,Wu T,Zheng S,Huang Y,Wang L
Wed Sep 01 00:00:00 EDT 2021
Triclosan regulates the Nrf2/HO-1 pathway through the PI3K/Akt/JNK signaling cascade to induce oxidative damage in neurons.
Environmental toxicology
Wang D,Liu J,Jiang H
Wed Sep 01 00:00:00 EDT 2021
Sinapic acid attenuates muscle atrophy in streptozotocin-induced diabetic mice.
Iranian journal of basic medical sciences
Xianchu L,Ming L,Changhao C,Beiwang D,Jingtao X
Wed Dec 01 00:00:00 EST 2021
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Acta cirurgica brasileira
Xu J,Zhan T,Zheng W,Huang YK,Chen K,Zhang XH,Ren P,Huang X
Fri Jan 29 00:00:00 EST 2021
Exogenous L-carnitine ameliorates burn-induced cellular and mitochondrial injury of hepatocytes by restoring CPT1 activity.
Nutrition & metabolism
Li P,Xia Z,Kong W,Wang Q,Zhao Z,Arnold A,Xu Q,Xu J
Thu Jun 24 00:00:00 EDT 2021
Salmonella Infantis Delays the Death of Infected Epithelial Cells to Aggravate Bacterial Load by Intermittent Phosphorylation of Akt With SopB.
Frontiers in immunology
Chu BX,Li YN,Liu N,Yuan LX,Chen SY,Zhu YH,Wang JF
Mon Feb 14 00:00:00 EST 2022
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
Neuroscience
Quan X,Song L,Zheng X,Liu S,Ding H,Li S,Xu G,Li X,Liu L
Thu Apr 15 00:00:00 EDT 2021
The molecular mechanism underlying mitophagy-mediated hippocampal neuron apoptosis in diabetes-related depression.
Journal of cellular and molecular medicine
Liu J,Liu L,Han YS,Yi J,Guo C,Zhao HQ,Ling J,Wang YH
Sun Aug 01 00:00:00 EDT 2021
African Swine Fever Virus pE199L Induces Mitochondrial-Dependent Apoptosis.
Viruses
Li T,Zhao G,Zhang T,Zhang Z,Chen X,Song J,Wang X,Li J,Huang L,Wen L,Li C,Zhao D,He X,Bu Z,Zheng J,Weng C
Mon Nov 08 00:00:00 EST 2021
African Swine Fever Virus pE199L Induces Mitochondrial-Dependent Apoptosis.
Viruses
Li T,Zhao G,Zhang T,Zhang Z,Chen X,Song J,Wang X,Li J,Huang L,Wen L,Li C,Zhao D,He X,Bu Z,Zheng J,Weng C
Mon Nov 08 00:00:00 EST 2021
Wogonin alleviates liver injury in sepsis through Nrf2-mediated NF-κB signalling suppression.
Journal of cellular and molecular medicine
Dai JM,Guo WN,Tan YZ,Niu KW,Zhang JJ,Liu CL,Yang XM,Tao KS,Chen ZN,Dai JY
Tue Jun 01 00:00:00 EDT 2021
Protective effects of safranal on hypoxia/reoxygenation-induced injury in H9c2 cardiac myoblasts via the PI3K/AKT/GSK3β signaling pathway.
Experimental and therapeutic medicine
Wang H,Zheng B,Che K,Han X,Li L,Wang H,Liu Y,Shi J,Sun S
Wed Dec 01 00:00:00 EST 2021
Erythropoietin Attenuates Experimental Contrast-Induced Nephrology: A Role for the Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Signaling Pathway.
Frontiers in medicine
Yang J,Zhou J,Wang X,Ji L,Wang S,Chen X,Yang L
Sun May 02 00:00:00 EDT 2021
Nanoarmour-shielded single-cell factory for bacteriotherapy of Parkinson's disease.
Journal of controlled release : official journal of the Controlled Release Society
Zhou X,Guo Q,Guo M,Li B,Peng W,Wang D,Ming D,Zheng B
Sun Oct 10 00:00:00 EDT 2021
Downregulation of CD151 induces oxidative stress and apoptosis in trophoblast cells via inhibiting ERK/Nrf2 signaling pathway in preeclampsia.
Free radical biology & medicine
Wang Z,Cai B,Cao C,Lv H,Dai Y,Zheng M,Zhao G,Peng Y,Gou W,Wang J,Liu D,Hu Y
Sat Feb 20 00:00:00 EST 2021
BLM interaction with EZH2 regulates MDM2 expression and is a poor prognostic biomarker for prostate cancer.
American journal of cancer research
Ruan Y,Xu H,Ji X,Zhao J
Fri May 07 00:00:00 EDT 2021
Myricanol Inhibits Platelet Derived Growth Factor-BB-Induced Vascular Smooth Muscle Cells Proliferation and Migration in vitro and Intimal Hyperplasia in vivo by Targeting the Platelet-Derived Growth Factor Receptor-β and NF-κB Signaling.
Frontiers in physiology
Fan S,Wang C,Huang K,Liang M
Wed Feb 23 00:00:00 EST 2022
Cyclovirobuxine inhibits the progression of clear cell renal cell carcinoma by suppressing the IGFBP3-AKT/STAT3/MAPK-Snail signalling pathway.
International journal of biological sciences
Liu Y,Lv H,Li X,Liu J,Chen S,Chen Y,Jin Y,An R,Yu S,Wang Z
Tue Feb 22 00:00:00 EST 2022
Omeprazole improves chemosensitivity of gastric cancer cells by m6A demethylase FTO-mediated activation of mTORC1 and DDIT3 up-regulation.
Bioscience reports
Feng S,Qiu G,Yang L,Feng L,Fan X,Ren F,Huang K,Chen Y
Fri Jan 29 00:00:00 EST 2021
Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway.
Pharmaceutical biology
Feng Z,Wang C,Meng Q,Wu J,Sun H
Wed Dec 01 00:00:00 EST 2021
The Effect of Hispidulin, a Flavonoid from Salvia plebeia, on Human Nasopharyngeal Carcinoma CNE-2Z Cell Proliferation, Migration, Invasion, and Apoptosis.
Molecules (Basel, Switzerland)
Dai Y,Sun X,Li B,Ma H,Wu P,Zhang Y,Zhu M,Li HM,Qin M,Wu CZ
Sun Mar 14 00:00:00 EST 2021
NUDCD1 knockdown inhibits the proliferation, migration, and invasion of pancreatic cancer via the EMT process.
Aging
Shi C,Weng M,Zhu H,Guo Y,Xu D,Jin H,Wei B,Cao Z
Thu Jul 29 00:00:00 EDT 2021
The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas.
BMC endocrine disorders
Wang S,Wang A,Zhang Y,Zhu K,Wang X,Chen Y,Wu J
Tue Nov 23 00:00:00 EST 2021
Design and Synthesis of Novel Betulin Derivatives Containing Thio-/Semicarbazone Moieties as Apoptotic Inducers through Mitochindria-Related Pathways.
Molecules (Basel, Switzerland)
Wang J,Wu J,Han Y,Zhang J,Lin Y,Wang H,Wang J,Liu J,Bu M
Thu Oct 21 00:00:00 EDT 2021
Inhibition of BAG3 enhances the anticancer effect of shikonin in hepatocellular carcinoma.
American journal of cancer research
Lu J,Liu SY,Zhang J,Yang GM,Gao GB,Yu NN,Li YP,Li YX,Ma ZQ,Wang Y,Lu CH
Sat Aug 07 00:00:00 EDT 2021
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
BMC complementary medicine and therapies
Tai H,Jiang XL,Lan ZM,Li Y,Kong L,Yao SC,Song N,Lv MJ,Wu J,Yang P,Xiao XS,Yang GL,Kuang JS,Jia LQ
Mon Mar 22 00:00:00 EDT 2021
SAA1 knockdown promotes the apoptosis of glioblastoma cells via downregulation of AKT signaling.
Journal of Cancer
Zhang H,Xu Y,Deng G,Yuan F,Tan Y,Gao L,Sun Q,Qi Y,Yang K,Geng R,Jiang H,Liu B,Chen Q
Fri Apr 16 00:00:00 EDT 2021
A-24, a steroidal saponin from Allium chinense, induced apoptosis, autophagy and migration inhibition in p53 wild-type and p53-deficient gastric cancer cells.
Chemico-biological interactions
Xu J,Wang Y,Wang Y,Wang Z,He X
Fri Oct 01 00:00:00 EDT 2021
RSL3 enhances the antitumor effect of cisplatin on prostate cancer cells via causing glycolysis dysfunction.
Biochemical pharmacology
Li M,Chen X,Wang X,Wei X,Wang D,Liu X,Xu L,Batu W,Li Y,Guo B,Zhang L
Fri Oct 01 00:00:00 EDT 2021
SMAD2 regulates testicular development and testosterone synthesis in Hu sheep.
Theriogenology
Yang H,Wan Z,Jin Y,Wang F,Zhang Y
Fri Oct 15 00:00:00 EDT 2021
Prenatal exposure to di-n-butyl phthalate induces erectile dysfunction in male adult rats.
Ecotoxicology and environmental safety
Zhou X,Zhang T,Song L,Wang Y,Zhang Q,Cong R,Ji C,Luan J,Yao L,Zhang W,Song N,Wang S
Sun Aug 01 00:00:00 EDT 2021
Choline attenuates heat stress-induced oxidative injury and apoptosis in bovine mammary epithelial cells by modulating PERK/Nrf-2 signaling pathway.
Molecular immunology
Yang M,Kuang M,Wang G,Ali I,Tang Y,Yang C,Li Y,Li L
Thu Jul 01 00:00:00 EDT 2021
Anti-tumor effects of Solanum nigrum L. extraction on C6 high-grade glioma.
Journal of ethnopharmacology
Li JH,Li SY,Shen MX,Qiu RZ,Fan HW,Li YB
Mon Jun 28 00:00:00 EDT 2021
Rutaecarpine Inhibits Doxorubicin-Induced Oxidative Stress and Apoptosis by Activating AKT Signaling Pathway.
Frontiers in cardiovascular medicine
Liao ZQ,Jiang YN,Su ZL,Bi HL,Li JT,Li CL,Yang XL,Zhang Y,Xie X
Tue Jan 25 00:00:00 EST 2022
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.
Phytotherapy research : PTR
Luo C,Sun H,Peng J,Gao C,Bao L,Ji R,Zhang C,Zhu W,Jin Y
Mon Feb 01 00:00:00 EST 2021
Melatonin Alleviates Contrast-Induced Acute Kidney Injury by Activation of Sirt3.
Oxidative medicine and cellular longevity
Zhang C,Suo M,Liu L,Qi Y,Zhang C,Xie L,Zheng X,Ma C,Li J,Yang J,Bu P
Wed Dec 29 00:00:00 EST 2021
PBK/TOPK Inhibitor Suppresses the Progression of Prolactinomas.
Frontiers in endocrinology
Zhu K,Cheng X,Wang S,Zhang H,Zhang Y,Wang X,Chen Y,Wu J
Wed Mar 09 00:00:00 EST 2022
Dexmedetomidine attenuates myocardial ischemia-reperfusion injury in vitro by inhibiting NLRP3 Inflammasome activation.
BMC anesthesiology
Huang Y,Sun X,Juan Z,Zhang R,Wang R,Meng S,Zhou J,Li Y,Xu K,Xie K
Tue Apr 06 00:00:00 EDT 2021
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Oncology letters
Wang P,Wang C,Liu C
Fri Jan 01 00:00:00 EST 2021
Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p.
Mediators of inflammation
Wang L,Li S,Qi L,Ling L
Thu Mar 31 00:00:00 EDT 2022
Evaluation of piggyBac-mediated anti-CD19 CAR-T cells after ex vivo expansion with aAPCs or magnetic beads.
Journal of cellular and molecular medicine
Yang LR,Li L,Meng MY,Wang WJ,Yang SL,Zhao YY,Wang RQ,Gao H,Tang WW,Yang Y,Yang LL,Liao LW,Hou ZL
Fri Jan 01 00:00:00 EST 2021
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Canadian journal of physiology and pharmacology
Ding F,Yang S
Wed Sep 01 00:00:00 EDT 2021
Hippocampal alpha-synuclein mediates depressive-like behaviors.
Brain, behavior, and immunity
Du T,Li G,Luo H,Pan Y,Xu Q,Ma K
Thu Jul 01 00:00:00 EDT 2021
Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells.
Journal of hazardous materials
Xiaoli F,Yaqing Z,Ruhui L,Xuan L,Aijie C,Yanli Z,Chen H,Lili C,Longquan S
Sun Aug 15 00:00:00 EDT 2021
PPP2R2A affects embryonic implantation by regulating the proliferation and apoptosis of Hu sheep endometrial stromal cells.
Theriogenology
Li X,Yao X,Xie H,Zhang G,Deng M,Deng K,Gao X,Bao Y,Li K,Wang F
Wed Dec 01 00:00:00 EST 2021
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
Cell death discovery
Li P,Cao S,Huang Y,Zhang Y,Liu J,Cai X,Zhou L,Li J,Jiang Z,Ding L,Zheng Z,Li S,Ye Q
Thu Jul 29 00:00:00 EDT 2021
Downregulating Long Non-coding RNAs CTBP1-AS2 Inhibits Colorectal Cancer Development by Modulating the miR-93-5p/TGF-β/SMAD2/3 Pathway.
Frontiers in oncology
Li Q,Yue W,Li M,Jiang Z,Hou Z,Liu W,Ma N,Gan W,Li Y,Zhou T,Yue W,Chen S
Tue May 04 00:00:00 EDT 2021
A SMOC2 variant inhibits BMP signaling by competitively binding to BMPR1B and causes growth plate defects.
Bone
Long F,Shi H,Li P,Guo S,Ma Y,Wei S,Li Y,Gao F,Gao S,Wang M,Duan R,Wang X,Yang K,Sun W,Li X,Li J,Liu Q
Fri Jan 01 00:00:00 EST 2021
Moderate mechanical stress suppresses the IL-1β-induced chondrocyte apoptosis by regulating mitochondrial dynamics.
Journal of cellular physiology
Zhang J,Hao X,Chi R,Qi J,Xu T
Mon Nov 01 00:00:00 EDT 2021
Methylation of TMEM176A, a key ERK signaling regulator, is a novel synthetic lethality marker of ATM inhibitors in human lung cancer.
Epigenomics
Li H,Yang W,Zhang M,He T,Zhou F,G Herman J,Hu L,Guo M
Wed Sep 01 00:00:00 EDT 2021
Arsenic trioxide induces expression of BCL-2 expression via NF-κB and p38 MAPK signaling pathways in BEAS-2B cells during apoptosis.
Ecotoxicology and environmental safety
Tang J,Yao C,Liu Y,Yuan J,Wu L,Hosoi K,Yu S,Huang C,Wei H,Chen G
Fri Oct 01 00:00:00 EDT 2021
Protective effect of recombinant Lactobacillus plantarum against H2O2-induced oxidative stress in HUVEC cells.
Journal of Zhejiang University. Science. B
Wang G,Hao M,Liu Q,Jiang Y,Huang H,Yang G,Wang C
Sat May 15 00:00:00 EDT 2021
Sempervirine Mediates Autophagy and Apoptosis via the Akt/mTOR Signaling Pathways in Glioma Cells.
Frontiers in pharmacology
Li G,Zhong Y,Wang W,Jia X,Zhu H,Jiang W,Song Y,Xu W,Wu S
Sat Dec 18 00:00:00 EST 2021
BCL2 enhances survival of porcine pluripotent stem cells through promoting FGFR2.
Cell proliferation
Zhu Z,Pan Q,Zhao W,Wu X,Yu S,Shen Q,Zhang J,Yue W,Peng S,Li N,Zhang S,Lei A,Hua J
Fri Jan 01 00:00:00 EST 2021
Imbalance of Autophagy and Apoptosis Induced by Oxidative Stress May Be Involved in Thyroid Damage Caused by Sleep Deprivation in Rats.
Oxidative medicine and cellular longevity
Li Y,Zhang W,Liu M,Zhang Q,Lin Z,Jia M,Liu D,Lin L
Tue Jan 25 00:00:00 EST 2022
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells.
Journal of cellular and molecular medicine
Wu W,Dong J,Gou H,Geng R,Yang X,Chen D,Xiang B,Zhang Z,Ren S,Chen L,Liu J
Sun Aug 01 00:00:00 EDT 2021
MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer.
Frontiers in oncology
Qian XL,Zhou F,Xu S,Jiang J,Chen ZP,Wang SK,Zuo Y,Ni C
Sun May 23 00:00:00 EDT 2021
Endogenous conversion of n-6 to n-3 polyunsaturated fatty acids facilitates the repair of cardiotoxin-induced skeletal muscle injury in fat-1 mice.
Aging
Wang ZG,Zhu ZQ,He ZY,Cheng P,Liang S,Chen AM,Yang Q
Wed Mar 10 00:00:00 EST 2021
Knockdown of RIPK2 Inhibits Proliferation and Migration, and Induces Apoptosis via the NF-κB Signaling Pathway in Gastric Cancer.
Frontiers in genetics
Yang Q,Tian S,Liu Z,Dong W
Sat Feb 27 00:00:00 EST 2021
Targeting Glycogen Synthase Kinase 3 Beta Regulates CD47 Expression After Myocardial Infarction in Rats via the NF-κB Signaling Pathway.
Frontiers in pharmacology
Xu LN,Wang SH,Su XL,Komal S,Fan HK,Xia L,Zhang LR,Han SN
Fri Aug 06 00:00:00 EDT 2021
Dihydromyricetin attenuates heat stress-induced apoptosis in dairy cow mammary epithelial cells through suppressing mitochondrial dysfunction.
Ecotoxicology and environmental safety
Wang HL,Xing GD,Qian Y,Sun XF,Zhong JF,Chen KL
Sat May 01 00:00:00 EDT 2021
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
Frontiers in pharmacology
Wang Y,Shen H,Sun Q,Zhao L,Liu H,Ye L,Xu Y,Cai J,Li Y,Gao L,Tan Y,Liu B,Chen Q
Fri Aug 13 00:00:00 EDT 2021
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
Frontiers in pharmacology
Wang Y,Shen H,Sun Q,Zhao L,Liu H,Ye L,Xu Y,Cai J,Li Y,Gao L,Tan Y,Liu B,Chen Q
Fri Aug 13 00:00:00 EDT 2021
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
Frontiers in pharmacology
Wang Y,Shen H,Sun Q,Zhao L,Liu H,Ye L,Xu Y,Cai J,Li Y,Gao L,Tan Y,Liu B,Chen Q
Fri Aug 13 00:00:00 EDT 2021
The New PI3K/mTOR Inhibitor GNE-477 Inhibits the Malignant Behavior of Human Glioblastoma Cells.
Frontiers in pharmacology
Wang Y,Shen H,Sun Q,Zhao L,Liu H,Ye L,Xu Y,Cai J,Li Y,Gao L,Tan Y,Liu B,Chen Q
Fri Aug 13 00:00:00 EDT 2021
Tanshinone IIA alleviates acute ethanol-induced myocardial apoptosis mainly through inhibiting the expression of PDCD4 and activating the PI3K/Akt pathway.
Phytotherapy research : PTR
Deng H,Yu B,Li Y
Sun Aug 01 00:00:00 EDT 2021
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Stem cells (Dayton, Ohio)
Luo L,Jian X,Sun H,Qin J,Wang Y,Zhang J,Shen Z,Yang D,Li C,Zhao P,Liu M,Tian Z,Zhou Y
Thu Apr 01 00:00:00 EDT 2021
Novel biomarkers for post-contrast acute kidney injury identified from long non-coding RNA expression profiles.
International journal of biological sciences
Chen G,Liu B,Chen S,Li H,Liu J,Mai Z,Chen E,Zhou C,Sun G,Guo Z,Lei L,Huang S,Zhang L,Li M,Tan N,Li H,Liao Y,Liu J,Chen J,Liu Y
Wed Jan 19 00:00:00 EST 2022
Silica Nanoparticles Promote α-Synuclein Aggregation and Parkinson's Disease Pathology.
Frontiers in neuroscience
Yuan X,Yang Y,Xia D,Meng L,He M,Liu C,Zhang Z
Tue Feb 01 00:00:00 EST 2022
Typical phthalic acid esters induce apoptosis by regulating the PI3K/Akt/Bcl-2 signaling pathway in rat insulinoma cells.
Ecotoxicology and environmental safety
Li L,Wang F,Zhang J,Wang K,De X,Li L,Zhang Y
Fri Jan 15 00:00:00 EST 2021
Ropivacaine Induces Cell Cycle Arrest in the G0/G1 Phase and Apoptosis of PC12 Cells via Inhibiting Mitochondrial STAT3 Translocation.
Inflammation
Zeng L,Li A,Zhang Z,Zhang F,Chen H,Wang Y,Ding X,Luo H
Wed Dec 01 00:00:00 EST 2021
Pilose Antler Peptide-3.2KD Ameliorates Adriamycin-Induced Myocardial Injury Through TGF-β/SMAD Signaling Pathway.
Frontiers in cardiovascular medicine
Xu Y,Qu X,Zhou J,Lv G,Han D,Liu J,Liu Y,Chen Y,Qu P,Huang X
Tue Jun 15 00:00:00 EDT 2021
Polystyrene microplastics induce blood-testis barrier disruption regulated by the MAPK-Nrf2 signaling pathway in rats.
Environmental science and pollution research international
Li S,Wang Q,Yu H,Yang L,Sun Y,Xu N,Wang N,Lei Z,Hou J,Jin Y,Zhang H,Li L,Xu F,Zhang L
Wed Sep 01 00:00:00 EDT 2021
Scoparone inhibits pancreatic cancer through PI3K/Akt signaling pathway.
World journal of gastrointestinal oncology
Li N,Yang F,Liu DY,Guo JT,Ge N,Sun SY
Wed Sep 15 00:00:00 EDT 2021
Biochanin A Inhibits Glioblastoma Growth via Restricting Glycolysis and Mitochondrial Oxidative Phosphorylation.
Frontiers in oncology
Dong Q,Li Q,Duan L,Yin H,Wang X,Liu Y,Wang B,Li K,Yao X,Yuan G,Pan Y
Tue Nov 07 00:00:00 EST 2023
Maternally expressed 3 protects the intestinal barrier from cardiac arrest-induced ischemia/reperfusion injury via miR-34a-3p/sirtuin 1/nuclear factor kappa B signaling.
Annals of translational medicine
Huang X,Pan M,Du P,Chen Y,Zhang C,Lu W,Lin J
Fri Jan 01 00:00:00 EST 2021
The neuroprotective effects of isoquercitrin purified from apple pomace by high-speed countercurrent chromatography in the MPTP acute mouse model of Parkinson's disease.
Food & function
Liu C,Wang W,Li H,Liu J,Zhang P,Cheng Y,Qin X,Hu Y,Wei Y
Wed Jul 07 00:00:00 EDT 2021
Quercetin Alleviates Intervertebral Disc Degeneration by Modulating p38 MAPK-Mediated Autophagy.
BioMed research international
Zhang S,Liang W,Abulizi Y,Xu T,Cao R,Xun C,Zhang J,Sheng W
Mon Sep 20 00:00:00 EDT 2021
Quercetin Alleviates Intervertebral Disc Degeneration by Modulating p38 MAPK-Mediated Autophagy.
BioMed research international
Zhang S,Liang W,Abulizi Y,Xu T,Cao R,Xun C,Zhang J,Sheng W
Mon Sep 20 00:00:00 EDT 2021
Xenon Nanobubbles for the Image-Guided Preemptive Treatment of Acute Ischemic Stroke via Neuroprotection and Microcirculatory Restoration.
ACS applied materials & interfaces
Jin J,Li M,Li J,Li B,Duan L,Yang F,Gu N
Wed Sep 22 00:00:00 EDT 2021
Macrophages mediated delivery of chlorin e6 and treatment of lung cancer by photodynamic reprogramming.
International immunopharmacology
Yu TT,Sang XY,Han N,Peng XC,Li QR,Xu X,Xiao RC,Xu HZ,Chen X,Wang MF,Li TF
Mon Nov 01 00:00:00 EDT 2021
RNF43 overexpression attenuates the Wnt/β-catenin signalling pathway to suppress tumour progression in cholangiocarcinoma.
Oncology letters
Pangestu NS,Chueakwon P,Talabnin K,Khiaowichit J,Talabnin C
Wed Dec 01 00:00:00 EST 2021
Effect of Perinatal Vitamin D Deficiency on Lung Mesenchymal Stem Cell Differentiation and Injury Repair Potential.
American journal of respiratory cell and molecular biology
Sakurai R,Singh H,Wang Y,Harb A,Gornes C,Liu J,Rehan VK
Mon Nov 01 00:00:00 EDT 2021
Early-senescent bone marrow mesenchymal stem cells promote C2C12 cell myogenic differentiation by preventing the nuclear translocation of FOXO3.
Life sciences
Che J,Xu C,Wu Y,Jia P,Han Q,Ma Y,Wang X,Du Y,Zheng Y
Thu Jul 15 00:00:00 EDT 2021
Betaine alleviates right ventricular failure via regulation of Rho A/ROCK signaling pathway in rats with pulmonary arterial hypertension.
European journal of pharmacology
Lv Y,Ma P,Wang J,Xu Q,Fan J,Yan L,Ma P,Zhou R
Fri Nov 05 00:00:00 EDT 2021
Venlafaxine and L-Thyroxine Treatment Combination: Impact on Metabolic and Synaptic Plasticity Changes in an Animal Model of Coexisting Depression and Hypothyroidism.
Cells
Głombik K,Detka J,Budziszewska B
Sat Jun 05 00:00:00 EDT 2021
Tunicamycin-Induced Endoplasmic Reticulum Stress Promotes Breast Cancer Cell MDA-MB-231 Apoptosis through Inhibiting Wnt/β-Catenin Signaling Pathway.
Journal of healthcare engineering
You Z,He L,Yan N
Mon Feb 21 00:00:00 EST 2022
Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments.
PeerJ
Lei X,Chen G,Li J,Wen W,Gong J,Fu J
Wed Apr 27 00:00:00 EDT 2022
LINC00857 contributes to proliferation and lymphomagenesis by regulating miR-370-3p/CBX3 axis in diffuse large B-cell lymphoma.
Carcinogenesis
Huang Y,Lin Y,Song X,Wu D
Fri May 28 00:00:00 EDT 2021
Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells.
Journal of nanobiotechnology
Xu HZ,Li TF,Wang C,Ma Y,Liu Y,Zheng MY,Liu ZJ,Chen JB,Li K,Sun SK,Komatsu N,Xu YH,Zhao L,Chen X
Mon Sep 06 00:00:00 EDT 2021
Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells.
Journal of nanobiotechnology
Xu HZ,Li TF,Wang C,Ma Y,Liu Y,Zheng MY,Liu ZJ,Chen JB,Li K,Sun SK,Komatsu N,Xu YH,Zhao L,Chen X
Mon Sep 06 00:00:00 EDT 2021
Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells.
Journal of nanobiotechnology
Xu HZ,Li TF,Wang C,Ma Y,Liu Y,Zheng MY,Liu ZJ,Chen JB,Li K,Sun SK,Komatsu N,Xu YH,Zhao L,Chen X
Mon Sep 06 00:00:00 EDT 2021
Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells.
Journal of nanobiotechnology
Xu HZ,Li TF,Wang C,Ma Y,Liu Y,Zheng MY,Liu ZJ,Chen JB,Li K,Sun SK,Komatsu N,Xu YH,Zhao L,Chen X
Mon Sep 06 00:00:00 EDT 2021
Salidroside Attenuates Doxorubicin-Induced Cardiac Dysfunction Partially Through Activation of QKI/FoxO1 Pathway.
Journal of cardiovascular translational research
Yan F,Liu R,Zhuang X,Li R,Shi H,Gao X
Thu Apr 01 00:00:00 EDT 2021
Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.
Frontiers in pharmacology
Xu ZQ,Zhang JJ,Kong N,Zhang GY,Ke P,Han T,Su DF,Liu C
Tue May 18 00:00:00 EDT 2021
Exploring the Therapeutic Mechanism of Tingli Dazao Xiefei Decoction on Heart Failure Based on Network Pharmacology and Experimental Study.
Evidence-based complementary and alternative medicine : eCAM
Zhao DD,Zhang XQ,Yang T,Liu Q,Lan ZZ,Yang XL,Qu HY,Zhou H
Thu Apr 28 00:00:00 EDT 2022
Role of Glycated High Mobility Group Box-1 in Gastric Cancer.
International journal of molecular sciences
Kishi S,Nishiguchi Y,Honoki K,Mori S,Fujiwara-Tani R,Sasaki T,Fujii K,Kawahara I,Goto K,Nakashima C,Kido A,Tanaka Y,Luo Y,Kuniyasu H
Thu May 13 00:00:00 EDT 2021
Suppression of Sox4 protects against myocardial ischemic injury by reduction of cardiac apoptosis in mice.
Journal of cellular physiology
Zhang L,Lv L,Zheng N,Li R,Yang R,Li T,Li Y,Liu Y,Luo H,Li X,Zhou Y,Shan H,Bai B,Liang H
Mon Feb 01 00:00:00 EST 2021
PDGF-BB/SA/Dex injectable hydrogels accelerate BMSC-mediated functional full thickness skin wound repair by promoting angiogenesis.
Journal of materials chemistry. B
Zhang Z,Li Z,Wang Y,Wang Q,Yao M,Zhao L,Shi J,Guan F,Ma S
Sat Aug 21 00:00:00 EDT 2021
The regulation of Ero1-alpha in homocysteine-induced macrophage apoptosis and vulnerable plaque formation in atherosclerosis.
Atherosclerosis
Zhang N,Zhu L,Wu X,Yan R,Yang S,Jiang X,Liu X,Liu X,Yan N,Cong G,Yang Z,Jia S
Fri Oct 01 00:00:00 EDT 2021
Oxidative stress-mediated apoptosis is involved in bisphenol S-induced reproductive toxicity in male C57BL/6 mice.
Journal of applied toxicology : JAT
Dai W,He QZ,Zhu BQ,Zeng HC
Mon Nov 01 00:00:00 EDT 2021
Vitamin E regulates bovine granulosa cell apoptosis via NRF2-mediated defence mechanism by activating PI3K/AKT and ERK1/2 signalling pathways.
Reproduction in domestic animals = Zuchthygiene
Wang M,Li Y,Gao Y,Li Q,Cao Y,Shen Y,Chen P,Yan J,Li J
Sun Aug 01 00:00:00 EDT 2021
Cyanidin-3-glucoside suppresses the progression of lung adenocarcinoma by downregulating TP53I3 and inhibiting PI3K/AKT/mTOR pathway.
World journal of surgical oncology
Chen X,Zhang W,Xu X
Fri Aug 06 00:00:00 EDT 2021
Pinocembrin Inhibits the Proliferation and Metastasis of Breast Cancer via Suppression of the PI3K/AKT Signaling Pathway.
Frontiers in oncology
Zhu X,Li R,Wang C,Zhou S,Fan Y,Ma S,Gao D,Gai N,Yang J
Tue Aug 03 00:00:00 EDT 2021
Tetrahydropalmatine Regulates BDNF through TrkB/CAM Interaction to Alleviate the Neurotoxicity Induced by Methamphetamine.
ACS chemical neuroscience
Liu L,Liu M,Zhao W,Zhao YL,Wang Y
Wed Sep 15 00:00:00 EDT 2021
TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways.
International journal of molecular medicine
Kong L,Yu Y,Guan H,Jiang L,Sun F,Li X,Huang W,Li B
Sat May 01 00:00:00 EDT 2021
Ozone induces tolerance against cardiomyocytes oxygen-glucose deprivation/reperfusion through inhibition of autophagy pathway.
Experimental and therapeutic medicine
Xu L,Zhu L,Liu P,Wu Z,Zou Z
Sun Aug 01 00:00:00 EDT 2021
Mechanisms Underlying the Effects of Lianhua Qingwen on Sepsis-Induced Acute Lung Injury: A Network Pharmacology Approach.
Frontiers in pharmacology
Yang R,Yang H,Wei J,Li W,Yue F,Song Y,He X,Hu K
Tue Nov 02 00:00:00 EDT 2021
DNA methylation mediated RSPO2 to promote follicular development in mammals.
Cell death & disease
Zhou X,He Y,Li N,Bai G,Pan X,Zhang Z,Zhang H,Li J,Yuan X
Sat Jun 26 00:00:00 EDT 2021
Exploring the Critical Components and Therapeutic Mechanisms of Perilla frutescens L. in the Treatment of Chronic Kidney Disease via Network Pharmacology.
Frontiers in pharmacology
Yong C,Zhang Z,Huang G,Yang Y,Zhu Y,Qian L,Tian F,Liu L,Wu Q,Xu Z,Chen C,Zhao J,Gao K,Zhou E
Wed Dec 15 00:00:00 EST 2021
Role of the BDNF/TrkB/CREB signaling pathway in the cytotoxicity of bisphenol S in SK-N-SH cells.
Journal of biochemical and molecular toxicology
He QZ,Zhu BQ,Xu XN,Zeng HC
Tue Jun 01 00:00:00 EDT 2021
Targeting MUC1-C reverses the cisplatin resistance of esophageal squamous cell carcinoma in vitro and in vivo.
Translational cancer research
Zhao YQ,Wu T,Wang LF,Yin B,Shi M,Jiang B,Gong-Sun X,Song XM,Liu XY
Mon Feb 01 00:00:00 EST 2021
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Journal of experimental & clinical cancer research : CR
Xie C,Zhou X,Liang C,Li X,Ge M,Chen Y,Yin J,Zhu J,Zhong C
Tue Aug 24 00:00:00 EDT 2021
Aloin protects mice from diet-induced non-alcoholic steatohepatitis via activation of Nrf2/HO-1 signaling.
Food & function
Xu Q,Fan Y,Loor JJ,Liang Y,Lv H,Sun X,Jia H,Xu C
Thu Jan 21 00:00:00 EST 2021
Expression Level of ADAMTS1 in Granulosa Cells of PCOS Patients Is Related to Granulosa Cell Function, Oocyte Quality, and Embryo Development.
Frontiers in cell and developmental biology
Yang G,Yao G,Xu Z,Fan H,Liu X,He J,Kong Y,Kong D,Bai Y,He Q,Zhang T,Zhang J,Sun Y
Fri Apr 30 00:00:00 EDT 2021
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Experimental and molecular pathology
Fan H,Xin T,Dong X,Yang F,Zhang R,Feng S,He D,Guo H,Pang Q
Mon Feb 01 00:00:00 EST 2021
Effect of SOCS3 on apoptosis of human trophoblasts via adjustment of the JAK2/STAT3 signaling pathway in preterm birth.
Translational pediatrics
Yin Y,Qu L,Zhu D,Wu Y,Zhou X
Tue Jun 01 00:00:00 EDT 2021
CD36 promotes NLRP3 inflammasome activation via the mtROS pathway in renal tubular epithelial cells of diabetic kidneys.
Cell death & disease
Hou Y,Wang Q,Han B,Chen Y,Qiao X,Wang L
Fri May 21 00:00:00 EDT 2021
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
Journal of receptor and signal transduction research
Ma X,Zhang J,Wu Z,Wang X
Sun Aug 01 00:00:00 EDT 2021
The biological characteristics of the canine adenovirus type 1 from fox and the transcriptome analysis of the infected MDCK cell.
Cell biology international
Zhu Y,Sun J,Yan M,Lian S,Hu B,Lv S,Li Y,Zhang Y,Yan X
Sat May 01 00:00:00 EDT 2021
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
Food science & nutrition
Zhou S,Zhou Y,Yu J,Jiang L,Xiang Y,Wang J,Du Y,Cui X,Ge F
Thu Jul 01 00:00:00 EDT 2021
2-Methoxyestradiol synergizes with Erlotinib to suppress hepatocellular carcinoma by disrupting the PLAGL2-EGFR-HIF-1/2α signaling loop.
Pharmacological research
Zheng S,Ni J,Li Y,Lu M,Yao Y,Guo H,Jiao M,Jin T,Zhang H,Yuan A,Wang Z,Yang Y,Chen Z,Wu H,Hu W
Thu Jul 01 00:00:00 EDT 2021
Cordyceps acid alleviates lung cancer in nude mice.
Journal of biochemical and molecular toxicology
Wang J,Chen H,Li W,Shan L
Mon Mar 01 00:00:00 EST 2021
JWA suppresses proliferation in trastuzumab-resistant breast cancer by downregulating CDK12.
Cell death discovery
Liang Y,Qian C,Xie Y,Huang X,Chen J,Ren Y,Fu Z,Li Y,Zeng T,Yang F,Zhou J,Li W,Yin Y,Wang C
Fri Oct 22 00:00:00 EDT 2021
MiR-133a-3p relieves the oxidative stress induced trophoblast cell apoptosis through the BACH1/Nrf2/HO-1 signaling pathway.
Physiological research
Guo H,Wang Y,Jia W,Liu L
Wed Mar 17 00:00:00 EDT 2021
CITED4 mediates proliferation, apoptosis and steroidogenesis of Hu sheep granulosa cells in vitro.
Reproduction (Cambridge, England)
Yao X,Ei-Samahy MA,Xiao S,Wang Z,Meng F,Li X,Bao Y,Zhang Y,Wang Z,Fan Y,Wang F
Mon Mar 01 00:00:00 EST 2021
INHBA transfection regulates proliferation, apoptosis and hormone synthesis in sheep granulosa cells.
Theriogenology
Bao Y,Yao X,Li X,Ei-Samahy MA,Yang H,Liang Y,Liu Z,Wang F
Mon Nov 01 00:00:00 EDT 2021
ZNRF2 attenuates focal cerebral ischemia/reperfusion injury in rats by inhibiting mTORC1-mediated autophagy.
Experimental neurology
Gu C,Yang J,Luo Y,Ran D,Tan X,Xiang P,Fei H,Lu Y,Guo W,Tu Y,Liu X,Wang H
Sun Aug 01 00:00:00 EDT 2021
PGC1α Promotes Cisplatin Resistance in Ovarian Cancer by Regulating the HSP70/HK2/VDAC1 Signaling Pathway.
International journal of molecular sciences
Li Y,Kang J,Fu J,Luo H,Liu Y,Li Y,Sun L
Wed Mar 03 00:00:00 EST 2021
Apatinib combined with Keytruda treatment induces apoptosis of gastric carcinoma cells through CES4/miR-616-5p/DUSP2 axis.
Basic & clinical pharmacology & toxicology
Zhang F,Yin Y,Xu W,Zhou Z,Sun X,Li P
Mon Nov 01 00:00:00 EDT 2021
Cigarette smoke induced neural tube defects by down-regulating noggin expression.
Birth defects research
Yin C,Cai H,Yang D,Jian Y,Zhang J,Li Z,Wang D
Fri Jan 01 00:00:00 EST 2021
Co-modification with MSC membrane and PDA prevents Fe3O4-induced pulmonary toxicity in mice via AMPK-ULK1 axis.
Toxicology letters
Yao H,Yan J,Shao P,Wang Y,Liu T,Jiang J,Liu T
Fri Oct 15 00:00:00 EDT 2021
Co-modification with MSC membrane and PDA prevents Fe3O4-induced pulmonary toxicity in mice via AMPK-ULK1 axis.
Toxicology letters
Yao H,Yan J,Shao P,Wang Y,Liu T,Jiang J,Liu T
Fri Oct 15 00:00:00 EDT 2021
Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways.
Nutrition and cancer
Hu Z,Wang H,Fu Y,Ma K,Ma X,Wang J
Wed Sep 08 00:00:00 EDT 2021
Epigallocatechin-3-Gallate Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via Inhibition of Apoptosis and Promotion of Autophagy through the ROS/MAPK Signaling Pathway.
Oxidative medicine and cellular longevity
Wu D,Liu Z,Wang Y,Zhang Q,Li J,Zhong P,Xie Z,Ji A,Li Y
Fri May 28 00:00:00 EDT 2021
miR-335-5p suppresses gastric cancer progression by targeting MAPK10.
Cancer cell international
Gao Y,Wang Y,Wang X,Zhao C,Wang F,Du J,Zhang H,Shi H,Feng Y,Li D,Yan J,Yao Y,Hu W,Ding R,Zhang M,Wang L,Huang C,Zhang J
Fri Jan 22 00:00:00 EST 2021
A "dual-guide" bioinspired drug delivery strategy of a macrophage-based carrier against postoperative triple-negative breast cancer recurrence.
Journal of controlled release : official journal of the Controlled Release Society
Qiu Y,Ren K,Zhao W,Yu Q,Guo R,He J,Mei L,Liu Y,Tang J,Xu S,Li J,Wei J,Li M,Zhang Z,He Q
Sun Jan 10 00:00:00 EST 2021
LncRNA-Malat1 down-regulates miR-211-5p expression to promote neuronal damage from cerebral ischemia reperfusion injury.
Biochemical pharmacology
Tan X,Guo W,Peng Z,Gu C,Xiang P,Tu Y,Fei H,Liu X,Lu Y,Li M,Wang H,Luo Y,Yang J
Fri Oct 01 00:00:00 EDT 2021
Ivermectin has New Application in Inhibiting Colorectal Cancer Cell Growth.
Frontiers in pharmacology
Zhou S,Wu H,Ning W,Wu X,Xu X,Ma Y,Li X,Hu J,Wang C,Wang J
Tue Sep 07 00:00:00 EDT 2021
Ufbp1, a Key Player of Ufm1 Conjugation System, Protects Against Ketosis-Induced Liver Injury via Suppressing Smad3 Activation.
Frontiers in cell and developmental biology
Chen F,Sheng L,Xu C,Li J,Ali I,Li H,Cai Y
Tue Jul 27 00:00:00 EDT 2021
Danshensu derivative ADTM ameliorates CCl4‑induced acute liver injury in mice through inhibiting oxidative stress and apoptosis.
Pathology, research and practice
Jia S,Chen Q,Wu J,Yao X,Shao J,Cheng X,Zhang C,Cen D,Wang Y,Shen Z,Shan L,Yao X
Wed Dec 01 00:00:00 EST 2021
N-acetylcysteine ameliorate cytotoxic injury in piglets sertoli cells induced by zearalenone and deoxynivalenol.
Environmental science and pollution research international
Cao L,Zhao J,Xu J,Zhu L,Rahman SU,Feng S,Li Y,Wu J,Wang X
Mon Nov 01 00:00:00 EDT 2021
Dynamic observation of 5-fluorouracil-induced myocardial injury and mitochondrial autophagy in aging rats.
Experimental and therapeutic medicine
Li Y,Zhang Y,Zhou X,Lei X,Li X,Wei L
Wed Dec 01 00:00:00 EST 2021
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca2+-Activin A circuit in chronic cerebral hypoperfusion rats.
Aging
Zhang X,Shi X,Wang J,Xu Z,He J
Mon Aug 30 00:00:00 EDT 2021
Long noncoding RNA GAS5 accelerates diabetic wound healing and promotes lymphangiogenesis via miR-217/Prox1 axis.
Molecular and cellular endocrinology
He ZY,Huang MT,Cui X,Zhou ST,Wu Y,Zhang PH,Zhou J
Thu Jul 15 00:00:00 EDT 2021
Salusin-β Mediates High Glucose-Induced Inflammation and Apoptosis in Retinal Capillary Endothelial Cells via a ROS-Dependent Pathway in Diabetic Retinopathy.
Diabetes, metabolic syndrome and obesity : targets and therapy
Wang H,Zhang M,Zhou H,Cao L,Zhou J,Chen Q,Zhang X
Sat Apr 23 00:00:00 EDT 2022
Lactobacillus acidophilus ATCC 4356 Alleviates Renal Ischemia-Reperfusion Injury Through Antioxidant Stress and Anti-inflammatory Responses and Improves Intestinal Microbial Distribution.
Frontiers in nutrition
Zhang P,Han X,Zhang X,Zhu X
Sun May 30 00:00:00 EDT 2021
miR-132-3p promotes the cisplatin-induced apoptosis and inflammatory response of renal tubular epithelial cells by targeting SIRT1 via the NF-κB pathway.
International immunopharmacology
Han S,Lin F,Ruan Y,Zhao S,Yuan R,Ning J,Jiang K,Xie J,Li H,Li C,Rao T,Yu W,Xia Y,Zhou X,Cheng F
Fri Oct 01 00:00:00 EDT 2021
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
European journal of pharmacology
Zeng S,Chen L,Sun Q,Zhao H,Yang H,Ren S,Liu M,Meng X,Xu H
Sun Sep 05 00:00:00 EDT 2021
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
European journal of pharmacology
Zeng S,Chen L,Sun Q,Zhao H,Yang H,Ren S,Liu M,Meng X,Xu H
Sun Sep 05 00:00:00 EDT 2021
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
European journal of pharmacology
Zeng S,Chen L,Sun Q,Zhao H,Yang H,Ren S,Liu M,Meng X,Xu H
Sun Sep 05 00:00:00 EDT 2021
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
European journal of pharmacology
Zeng S,Chen L,Sun Q,Zhao H,Yang H,Ren S,Liu M,Meng X,Xu H
Sun Sep 05 00:00:00 EDT 2021
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
European journal of pharmacology
Cheng Z,Lv D,Luo M,Wang R,Guo Y,Yang X,Huang L,Li X,Li C,Shang FF,Huang B,Shen J,Luo S,Yan J
Sun Aug 15 00:00:00 EDT 2021
Ultrasound-Induced Destruction of Nitric Oxide-Loaded Microbubbles in the Treatment of Thrombus and Ischemia-Reperfusion Injury.
Frontiers in pharmacology
Liang Z,Chen H,Gong X,Shi B,Lin L,Tao F,Wu Q,Fang M,Li H,Lu C,Xu H,Zhao Y,Chen B
Fri Jan 28 00:00:00 EST 2022
Maslinic Acid Attenuates Ischemia/Reperfusion Injury-Induced Myocardial Inflammation and Apoptosis by Regulating HMGB1-TLR4 Axis.
Frontiers in cardiovascular medicine
Li Q,Xu M,Li Z,Li T,Wang Y,Chen Q,Wang Y,Feng J,Yin X,Lu C
Sat Dec 04 00:00:00 EST 2021
Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Peng X,Hao M,Zhao Y,Cai Y,Chen X,Chen H,Zhang Y,Dong L,Liu X,Ding C,Liu W,Yang M,Luo Y
Wed Dec 01 00:00:00 EST 2021
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.
Journal of oncology
Hu C,Cao Y,Li P,Tang X,Yang M,Gu S,Xiong K,Li T,Xiao T
Mon Apr 25 00:00:00 EDT 2022
RAS-association domain family 1A regulates the abnormal cell proliferation in psoriasis via inhibition of Yes-associated protein.
Journal of cellular and molecular medicine
Jia J,Wang N,Zheng Y,Mo X,Zhang Y,Ye S,Liu J,Yan F,Li H,Chen D
Tue Jun 01 00:00:00 EDT 2021
Panax notoginseng saponins reduces the cisplatin-induced acute renal injury by increasing HIF-1α/BNIP3 to inhibit mitochondrial apoptosis pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li Q,Zhang Y,Yang Y,Huang S,Zou X,Wei C,Liang T,Zhong X
Fri Oct 01 00:00:00 EDT 2021
P53 inhibitor pifithrin-α inhibits ropivacaine-induced neuronal apoptosis via the mitochondrial apoptosis pathway.
Journal of biochemical and molecular toxicology
Zeng L,Zhang F,Zhang Z,Xu M,Xu Y,Liu Y,Xu H,Sun X,Sang M,Luo H
Sun Aug 01 00:00:00 EDT 2021
Tubeimoside I Ameliorates Myocardial Ischemia-Reperfusion Injury through SIRT3-Dependent Regulation of Oxidative Stress and Apoptosis.
Oxidative medicine and cellular longevity
Lv D,Luo M,Cheng Z,Wang R,Yang X,Guo Y,Huang L,Li X,Huang B,Shen J,Luo S,Yan J
Mon Feb 07 00:00:00 EST 2022
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Clinical and experimental pharmacology & physiology
Lu C,Liu L,Chen S,Niu J,Li S,Xie W,Cheng X
Wed Dec 01 00:00:00 EST 2021
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Clinical and experimental pharmacology & physiology
Lu C,Liu L,Chen S,Niu J,Li S,Xie W,Cheng X
Wed Dec 01 00:00:00 EST 2021
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades.
Journal of ginseng research
Zhu S,Liu X,Xue M,Li Y,Cai D,Wang S,Zhang L
Mon Mar 01 00:00:00 EST 2021
Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway.
Drug design, development and therapy
Ma L,Wu F,Shao Q,Chen G,Xu L,Lu F
Mon Jan 10 00:00:00 EST 2022
Vagal Nerve Stimulation Protects Against Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting Autophagy and Apoptosis.
Neuropsychiatric disease and treatment
Zhang LN,Zhang XW,Li CQ,Guo J,Chen YP,Chen SL
Thu Apr 21 00:00:00 EDT 2022
Lobetyolin inhibits the proliferation of breast cancer cells via ASCT2 down-regulation-induced apoptosis.
Human & experimental toxicology
Chen Y,Tian Y,Jin G,Cui Z,Guo W,Zhang X,Liu X
Wed Dec 01 00:00:00 EST 2021
Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling.
BMC cancer
Wang F,Wang L,Qu C,Chen L,Geng Y,Cheng C,Yu S,Wang D,Yang L,Meng Z,Chen Z
Mon Apr 12 00:00:00 EDT 2021
Pemafibrate Pretreatment Attenuates Apoptosis and Autophagy during Hepatic Ischemia-Reperfusion Injury by Modulating JAK2/STAT3β/PPARα Pathway.
PPAR research
Cheng Z,Guo C
Tue Mar 30 00:00:00 EDT 2021
Pemafibrate Pretreatment Attenuates Apoptosis and Autophagy during Hepatic Ischemia-Reperfusion Injury by Modulating JAK2/STAT3β/PPARα Pathway.
PPAR research
Cheng Z,Guo C
Tue Mar 30 00:00:00 EDT 2021
A Nuclear Long Non-Coding RNA LINC00618 Accelerates Ferroptosis in a Manner Dependent upon Apoptosis.
Molecular therapy : the journal of the American Society of Gene Therapy
Wang Z,Chen X,Liu N,Shi Y,Liu Y,Ouyang L,Tam S,Xiao D,Liu S,Wen F,Tao Y
Wed Jan 06 00:00:00 EST 2021
Curcumin attenuates Adriamycin-resistance of acute myeloid leukemia by inhibiting the lncRNA HOTAIR/miR-20a-5p/WT1 axis.
Laboratory investigation; a journal of technical methods and pathology
Liu JM,Li M,Luo W,Sun HB
Fri Oct 01 00:00:00 EDT 2021
Dehydroabietic Acid Is a Novel Survivin Inhibitor for Gastric Cancer.
Plants (Basel, Switzerland)
Kim WJ,Kim W,Bae JM,Gim J,Kim SJ
Sat May 22 00:00:00 EDT 2021
Oxymatrine pretreatment protects H9c2 cardiomyocytes from hypoxia/reoxygenation injury by modulating the PI3K/Akt pathway.
Experimental and therapeutic medicine
Zhang Z,Qin X,Wang Z,Li Y,Chen F,Chen R,Li C,Zhang W,Zhang M
Tue Jun 01 00:00:00 EDT 2021
SIRT3 protects bovine mammary epithelial cells from heat stress damage by activating the AMPK signaling pathway.
Cell death discovery
Sun XC,Wang Y,Zeng HF,Xi YM,Lin H,Han ZY,Chen KL
Thu Oct 21 00:00:00 EDT 2021
Inhibition of α-Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice.
Oxidative medicine and cellular longevity
Li Y,Yuan Y,Li Y,Han D,Liu T,Yang N,Mi X,Hong J,Liu K,Song Y,He J,Zhou Y,Han Y,Shi C,Yu S,Zou P,Guo X,Li Z
Tue Jan 04 00:00:00 EST 2022
Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway.
Food & function
Xian M,Cai J,Zheng K,Liu Q,Liu Y,Lin H,Liang S,Wang S
Tue Sep 07 00:00:00 EDT 2021
Antagonizing effects of curcumin against mercury-induced autophagic death and trace elements disorder by regulating PI3K/AKT and Nrf2 pathway in the spleen.
Ecotoxicology and environmental safety
Zhao G,Qi L,Wang Y,Li X,Li Q,Tang X,Wang X,Wu C
Fri Oct 01 00:00:00 EDT 2021
Effects of MicroRNA-195-5p on Biological Behaviors and Radiosensitivity of Lung Adenocarcinoma Cells via Targeting HOXA10.
Oxidative medicine and cellular longevity
Yuan C,Bai R,Gao Y,Jiang X,Li S,Sun W,Li Y,Huang Z,Gong Y,Xie C
Mon Feb 28 00:00:00 EST 2022
Peptides Isolated from Yak Milk Residue Exert Antioxidant Effects through Nrf2 Signal Pathway.
Oxidative medicine and cellular longevity
Yang F,He X,Chen T,Liu J,Luo Z,Sun S,Qin D,Huang W,Tang Y,Liu C,Luo F
Fri Mar 04 00:00:00 EST 2022
Carnosol alleviates nonalcoholic fatty liver disease by inhibiting mitochondrial dysfunction and apoptosis through targeting of PRDX3.
Toxicology and applied pharmacology
Geng Y,Wang Y,Sun R,Kang X,Zhao H,Zhu M,Sun Y,Hu Y,Wang Z,Tian X,Zhao Y,Yao J
Wed Dec 01 00:00:00 EST 2021
The Kidney-Related Effects of Polystyrene Microplastics on Human Kidney Proximal Tubular Epithelial Cells HK-2 and Male C57BL/6 Mice.
Environmental health perspectives
Wang YL,Lee YH,Hsu YH,Chiu IJ,Huang CC,Huang CC,Chia ZC,Lee CP,Lin YF,Chiu HW
Sat May 01 00:00:00 EDT 2021
Curcumin Ameliorates Copper-Induced Neurotoxicity Through Inhibiting Oxidative Stress and Mitochondrial Apoptosis in SH-SY5Y Cells.
Neurochemical research
Xiang B,Li D,Chen Y,Li M,Zhang Y,Sun T,Tang S
Mon Feb 01 00:00:00 EST 2021
Ursolic Acid Inhibits Breast Cancer Metastasis by Suppressing Glycolytic Metabolism via Activating SP1/Caveolin-1 Signaling.
Frontiers in oncology
Wang S,Chang X,Zhang J,Li J,Wang N,Yang B,Pan B,Zheng Y,Wang X,Ou H,Wang Z
Wed Sep 29 00:00:00 EDT 2021
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Frontiers in cell and developmental biology
Cao W,Li Y,Sun H,Yang C,Zhu J,Xie C,Li X,Wu J,Geng S,Wang L,Sun L,Geng G,Han H,Zhong C
Fri Aug 06 00:00:00 EDT 2021
Anti-androgenetic alopecia effect of policosanol from Chinese wax by regulating abnormal hormone levels to suppress premature hair follicle entry into the regression phase.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang ZD,Feng Y,Sun L,Gan J,Li X,Ding WF,Chen XM
Thu Apr 01 00:00:00 EDT 2021
Hyper-O-GlcNAcylation impairs insulin response against reperfusion-induced myocardial injury and arrhythmias in obesity.
Biochemical and biophysical research communications
Jin L,Gao F,Jiang T,Liu B,Li C,Qin X,Zheng Q
Fri Jun 18 00:00:00 EDT 2021
Deficiency of NEAT1 prevented MPP+-induced inflammatory response, oxidative stress and apoptosis in dopaminergic SK-N-SH neuroblastoma cells via miR-1277-5p/ARHGAP26 axis.
Brain research
Zhou S,Zhang D,Guo J,Chen Z,Chen Y,Zhang J
Fri Jan 01 00:00:00 EST 2021
Verapamil ameliorates proximal tubular epithelial cells apoptosis and fibrosis in diabetic kidney.
European journal of pharmacology
Song Y,Guo F,Zhao Y,Zhao L,Fan X,Zhang Y,Liu Y,Qin G
Mon Nov 15 00:00:00 EST 2021
Drug-Loaded, Polyurethane Coated Nitinol Stents for the Controlled Release of Docetaxel for the Treatment of Oesophageal Cancer.
Pharmaceuticals (Basel, Switzerland)
Fouladian P,Jin Q,Arafat M,Song Y,Guo X,Blencowe A,Garg S
Thu Apr 01 00:00:00 EDT 2021
miR-98-5p protects against cerebral ischemia/reperfusion injury through anti-apoptosis and anti-oxidative stress in mice.
Journal of biochemistry
Yu S,Zhai J,Yu J,Yang Q,Yang J
Fri Mar 05 00:00:00 EST 2021
Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model.
Neuropharmacology
Lan J,Hu Y,Wang X,Zheng W,Liao A,Wang S,Li Y,Wang Y,Yang F,Chen D
Wed Sep 15 00:00:00 EDT 2021
The Role of TRPC6 in Renal Ischemia/Reperfusion and Cellular Hypoxia/Reoxygenation Injuries.
Frontiers in molecular biosciences
Hou X,Huang M,Zeng X,Zhang Y,Sun A,Wu Q,Zhu L,Zhao H,Liao Y
Tue Jul 27 00:00:00 EDT 2021
Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.
Bioorganic chemistry
Liang Y,Zhang M,Zhou P,Liu M,Li J,Wang Y
Fri Oct 01 00:00:00 EDT 2021
The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation.
Aging
Guo Y,Xiao Y,Guo H,Zhu H,Chen D,Wang J,Deng J,Lan J,Liu X,Zhang Q,Bai Y
Wed Jul 28 00:00:00 EDT 2021
Alisol A 24-acetate protects oxygen-glucose deprivation-induced brain microvascular endothelial cells against apoptosis through miR-92a-3p inhibition by targeting the B-cell lymphoma-2 gene.
Pharmaceutical biology
Zhou Y,Wei W,Shen J,Lu L,Lu T,Wang H,Xue X
Wed Dec 01 00:00:00 EST 2021
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
Frontiers in medicine
Tai H,Jiang XL,Song N,Xiao HH,Li Y,Cheng MJ,Yin XM,Chen YR,Yang GL,Jiang XY,Kuang JS,Lan ZM,Jia LQ
Sat May 22 00:00:00 EDT 2021
Inhibition of Notch1 signaling reduces hepatocyte injury in nonalcoholic fatty liver disease via autophagy.
Biochemical and biophysical research communications
Zhang M,Wu P,Li M,Guo Y,Tian T,Liao X,Tan S
Fri Apr 02 00:00:00 EDT 2021
Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics.
Nature communications
Ding RB,Chen P,Rajendran BK,Lyu X,Wang H,Bao J,Zeng J,Hao W,Sun H,Wong AH,Valecha MV,Yang EJ,Su SM,Choi TK,Liu S,Chan KI,Yang LL,Wu J,Miao K,Chen Q,Shim JS,Xu X,Deng CX
Mon May 24 00:00:00 EDT 2021
Dual-enzymatically cross-linked gelatin hydrogel promotes neural differentiation and neurotrophin secretion of bone marrow-derived mesenchymal stem cells for treatment of moderate traumatic brain injury.
International journal of biological macromolecules
Li J,Zhang D,Guo S,Zhao C,Wang L,Ma S,Guan F,Yao M
Thu Sep 30 00:00:00 EDT 2021
Case Report: 7-Ethyl-10-Hydroxycamptothecin, a DNA Topoisomerase I Inhibitor, Performs BRD4 Inhibitory Activity and Inhibits Human Leukemic Cell Growth.
Frontiers in pharmacology
Wang A,Li L,Li M,Wang S,Wang C
Thu Sep 16 00:00:00 EDT 2021
Systematic screening identifies a TEAD4-S100A13 axis modulating cisplatin sensitivity of oral squamous cell carcinoma cells.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Li R,Li W,He F,Zhang M,Luo H,Tang H
Fri Oct 01 00:00:00 EDT 2021
Gypenosides Inhibit Inflammatory Response and Apoptosis of Endothelial and Epithelial Cells in LPS-Induced ALI: A Study Based on Bioinformatic Analysis and in vivo/vitro Experiments.
Drug design, development and therapy
Tu Q,Zhu Y,Yuan Y,Guo L,Liu L,Yao L,Zou Y,Li J,Chen F
Thu Sep 30 00:00:00 EDT 2021
Antileukemic effect of caffeic acid 3,4-dihydroxyphenetyl ester. Evidences for its mechanisms of action.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Tang M,Xie X,Shi M,Xin W,Zheng G,Zhang Y,Zhang Z,Lian X
Fri Jan 01 00:00:00 EST 2021
Prognostic signature composed of transcription factors accurately predicts the prognosis of gastric cancer patients.
Cancer cell international
Zhou L,Chen Z,Wu Y,Lu H,Xin L
Wed Jul 07 00:00:00 EDT 2021
CircRNA RSF1 regulated ox-LDL induced vascular endothelial cells proliferation, apoptosis and inflammation through modulating miR-135b-5p/HDAC1 axis in atherosclerosis.
Biological research
Zhang X,Lu J,Zhang Q,Luo Q,Liu B
Tue Mar 23 00:00:00 EDT 2021
Yak milk-derived exosomal microRNAs regulate intestinal epithelial cells on proliferation in hypoxic environment.
Journal of dairy science
Gao HN,Ren FZ,Wen PC,Xie LX,Wang R,Yang ZN,Li YX
Mon Feb 01 00:00:00 EST 2021
Allicin can suppress the activity of vascular endothelial cells probably by regulating JAK2/STAT3 pathway.
Molecular and cellular biochemistry
Sun HH,Feng XM,Wang JC,Cai J
Fri Jan 01 00:00:00 EST 2021
20-HETE synthesis inhibition attenuates traumatic brain injury-induced mitochondrial dysfunction and neuronal apoptosis via the SIRT1/PGC-1α pathway: A translational study.
Cell proliferation
Cui W,Wu X,Shi Y,Guo W,Luo J,Liu H,Zheng L,Du Y,Wang P,Wang Q,Feng D,Ge S,Qu Y
Mon Feb 01 00:00:00 EST 2021
lncRNA AC007207.2 Promotes Malignant Properties of Osteosarcoma via the miR-1306-5p/SIRT7 Axis.
Cancer management and research
Dang Y,Zhou Y,Ou X,Wang Q,Wei D,Xie F
Wed Apr 27 00:00:00 EDT 2022
PRSS55 plays an important role in the structural differentiation and energy metabolism of sperm and is required for male fertility in mice.
Journal of cellular and molecular medicine
Zhu F,Li W,Zhou X,Chen X,Zheng M,Cui Y,Liu X,Guo X,Zhu H
Mon Feb 01 00:00:00 EST 2021
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
Frontiers in cardiovascular medicine
Wu X,Zhang T,Lyu P,Chen M,Ni G,Cheng H,Xu G,Li X,Wang L,Shang H
Tue Aug 03 00:00:00 EDT 2021
The screening of drug-induced nephrotoxicity using gold nanocluster-based ratiometric fluorescent probes.
Nanoscale
Liu Q,Li J,Liu X,Yuan L,Zhao L,Chang YT,Liu X,Peng J
Sat Aug 28 00:00:00 EDT 2021
Adiponectin alleviates the symptoms of ischemic renal disease by inhibiting renal cell apoptosis.
Life sciences
Zheng X,Liu D
Fri Jan 15 00:00:00 EST 2021
Methamphetamine mediates apoptosis of vascular smooth muscle cells via the chop-related endoplasmic reticulum stress pathway.
Toxicology letters
Tan X,Cai D,Chen N,Du S,Qiao D,Yue X,Wang T,Li J,Xie W,Wang H
Sun Oct 10 00:00:00 EDT 2021
The protective effects of resveratrol pretreatment in cyclophosphamide-induced rat ovarian injury: an vivo study.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Nie Z,Zhang L,Chen W,Zhang Y,Wang W,Hua R,Zhang T,Zhao C,Gong M,Wu H
Fri Oct 01 00:00:00 EDT 2021
The XBP1‒MARCH5‒MFN2 Axis Confers Endoplasmic Reticulum Stress Resistance by Coordinating Mitochondrial Fission and Mitophagy in Melanoma.
The Journal of investigative dermatology
Wang H,Yi X,Guo S,Wang S,Ma J,Zhao T,Shi Q,Tian Y,Wang H,Jia L,Gao T,Li C,Guo W
Wed Dec 01 00:00:00 EST 2021
Arctigenin inhibits cholangiocarcinoma progression by regulating cell migration and cell viability via the N-cadherin and apoptosis pathway.
Naunyn-Schmiedeberg's archives of pharmacology
Janthamala S,Jusakul A,Kongpetch S,Kimawaha P,Klanrit P,Loilome W,Namwat N,Techasen A
Fri Oct 01 00:00:00 EDT 2021
Schisandrin Protects against Norepinephrine-Induced Myocardial Hypertrophic Injury by Inhibiting the JAK2/STAT3 Signaling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Yang M,Jiang XC,Wang L,Cui DA,Zhang JY,Wang XR,Feng HP,Zhang K,Zhang K,Li JX,Wang XZ
Tue Jul 06 00:00:00 EDT 2021
MiR-223-3p targets FOXO3a to inhibit radiosensitivity in prostate cancer by activating glycolysis.
Life sciences
Zhou K,Wei Y,Li X,Yang X
Fri Oct 01 00:00:00 EDT 2021
miR‑451 suppresses the malignant characteristics of colorectal cancer via targeting SAMD4B.
Molecular medicine reports
Wu C,Liu X,Li B,Sun G,Peng C,Xiang D
Sun Aug 01 00:00:00 EDT 2021
LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance of Gastric Cancer Cells via Upregulating ATG5.
Frontiers in cell and developmental biology
Gui Z,Zhao Z,Sun Q,Shao G,Huang J,Zhao W,Kuang Y
Fri Nov 19 00:00:00 EST 2021
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang Z,Wu H,Huang S,Chen L,Chen X,Zhang W,Liao L,Zhang X
Tue Jun 01 00:00:00 EDT 2021
Exosomal miR-27 negatively regulates ROS production and promotes granulosa cells apoptosis by targeting SPRY2 in OHSS.
Journal of cellular and molecular medicine
Liu K,Yang W,Hu M,Xie W,Huang J,Cui M,He X,Nie X
Thu Apr 01 00:00:00 EDT 2021
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
Medical science monitor : international medical journal of experimental and clinical research
Li H,Zhao K,Li Y
Tue Mar 09 00:00:00 EST 2021
The miR-136-5p/ROCK1 axis suppresses invasion and migration, and enhances cisplatin sensitivity in head and neck cancer cells.
Experimental and therapeutic medicine
Yang B,Zang J,Yuan W,Jiang X,Zhang F
Thu Apr 01 00:00:00 EDT 2021
Lactoferrin ameliorates pathological cardiac hypertrophy related to mitochondrial quality control in aged mice.
Food & function
Huang L,Chen R,Liu L,Zhou Y,Chen Z
Sat Aug 21 00:00:00 EDT 2021
Myrtenol improves brain damage and promotes angiogenesis in rats with cerebral infarction by activating the ERK1/2 signalling pathway.
Pharmaceutical biology
Huang S,Tan Z,Cai J,Wang Z,Tian Y
Wed Dec 01 00:00:00 EST 2021
Avasimibe exerts anticancer effects on human glioblastoma cells via inducing cell apoptosis and cell cycle arrest.
Acta pharmacologica Sinica
Liu JY,Fu WQ,Zheng XJ,Li W,Ren LW,Wang JH,Yang C,Du GH
Fri Jan 01 00:00:00 EST 2021
Autophagy Induction Contributes to the Neuroprotective Impact of Intermittent Fasting on the Acutely Injured Spinal Cord.
Journal of neurotrauma
Yuan W,He X,Morin D,Barrière G,Liu X,Li J,Zhu Y
Mon Feb 01 00:00:00 EST 2021
N6-Methyladenosine Modification of LncRNA DUXAP9 Promotes Renal Cancer Cells Proliferation and Motility by Activating the PI3K/AKT Signaling Pathway.
Frontiers in oncology
Tan L,Tang Y,Li H,Li P,Ye Y,Cen J,Gui C,Luo J,Cao J,Wei J
Sat Jun 26 00:00:00 EDT 2021
IL13Rα1 prevents a castration resistant phenotype of prostate cancer by targeting hexokinase 2 for ubiquitin-mediated degradation.
Cancer biology & medicine
Feng T,Wang J,Cheng K,Lu Q,Zhao R,Wang S,Zhang Q,Ge L,Pan J,Song G,Wang L
Mon Oct 18 00:00:00 EDT 2021
Amyloid-β (25-35) regulates neuronal damage and memory loss via SIRT1/Nrf2 in the cortex of mice.
Journal of chemical neuroanatomy
Zhu L,Lu F,Jia X,Yan Q,Zhang X,Mu P
Thu Jul 01 00:00:00 EDT 2021
Anti-osteosarcoma effect of antiserum against cross antigen TPD52 between osteosarcoma and Trichinella spiralis.
Parasites & vectors
Yue TT,Zhang N,Li JH,Lu XY,Wang XC,Li X,Zhang HB,Cheng SQ,Wang BB,Gong PT,Zhang XC
Sun Sep 26 00:00:00 EDT 2021
Changes in histology, protein expression, and autophagy in dairy goat testes during nonbreeding season†.
Biology of reproduction
Xi H,Ren F,Li Y,Du Y,Wang L,Hu J
Mon Nov 15 00:00:00 EST 2021
Infection of humanized mice with a novel phlebovirus presented pathogenic features of severe fever with thrombocytopenia syndrome.
PLoS pathogens
Xu S,Jiang N,Nawaz W,Liu B,Zhang F,Liu Y,Wu X,Wu Z
Sat May 01 00:00:00 EDT 2021
Verapamil inhibits early acute liver failure through suppressing the NLRP3 inflammasome pathway.
Journal of cellular and molecular medicine
Han M,Li S,Li L
Mon May 24 00:00:00 EDT 2021
Maternal selenium deficiency suppresses proliferation, induces autophagy dysfunction and apoptosis in the placenta of mice.
Metallomics : integrated biometal science
Li M,Cheng W,Zhang L
Fri Nov 19 00:00:00 EST 2021
Glucocorticoids protect HEI-OC1 cells from tunicamycin-induced cell damage via inhibiting endoplasmic reticulum stress.
Open life sciences
Liu Z,Fei B,Xie L,Liu J,Chen X,Zhu W,Lv L,Ma W,Gao Z,Hou J,She W
Sun Apr 24 00:00:00 EDT 2022
Tubeimoside I improves endothelial function in sepsis via activation of SIRT3.
Laboratory investigation; a journal of technical methods and pathology
Yang X,Li X,Luo M,Li C,Huang L,Li X,Huang B,Shen J,Luo S,Yan J
Thu Jul 01 00:00:00 EDT 2021
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury.
Journal of neuroinflammation
Wang C,Xu T,Lachance BB,Zhong X,Shen G,Xu T,Tang C,Jia X
Thu Feb 18 00:00:00 EST 2021
A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone.
Molecular medicine (Cambridge, Mass.)
Fu Y,Xin Z,Ling Z,Xie H,Xiao T,Shen X,Lin J,Xu L,Jiang H
Thu Jul 22 00:00:00 EDT 2021
Inhibitory effect and mechanism of action (MOA) of hirsutine on the proliferation of T-cell leukemia Jurkat clone E6-1 cells.
PeerJ
Meng J,Su R,Wang L,Yuan B,Li L
Wed Apr 20 00:00:00 EDT 2022
Acetylcholine ameliorated hypoxia-induced oxidative stress and apoptosis in trophoblast cells via p38 MAPK/NF-κB pathway.
Molecular human reproduction
Wang Z,Zhao G,Zibrila AI,Li Y,Liu J,Feng W
Sat Aug 07 00:00:00 EDT 2021
CSF-CN contributes to cancer-induced bone pain via the MKP-1-mediated MAPK pathway.
Biochemical and biophysical research communications
Chen P,Pan M,Lin QS,Lin XZ,Lin Z
Fri Apr 02 00:00:00 EDT 2021
Honokiol induces paraptosis-like cell death of acute promyelocytic leukemia via mTOR & MAPK signaling pathways activation.
Apoptosis : an international journal on programmed cell death
Liu X,Gu Y,Bian Y,Cai D,Li Y,Zhao Y,Zhang Z,Xue M,Zhang L
Thu Apr 01 00:00:00 EDT 2021
125I seed implantation brachytherapy for glottic carcinoma: an experimental and clinical study.
American journal of cancer research
Jiao D,Zhou X,Yao Y,Chen J,Lei Q,Ren J,Han X
Fri May 07 00:00:00 EDT 2021
125I seed implantation brachytherapy for glottic carcinoma: an experimental and clinical study.
American journal of cancer research
Jiao D,Zhou X,Yao Y,Chen J,Lei Q,Ren J,Han X
Fri May 07 00:00:00 EDT 2021
Sinomenine Suppresses Development of Hepatocellular Carcinoma Cells via Inhibiting MARCH1 and AMPK/STAT3 Signaling Pathway.
Frontiers in molecular biosciences
Yang W,Feng Q,Li M,Su J,Wang P,Wang X,Yin Y,Wang X,Zhao M
Tue Jun 29 00:00:00 EDT 2021
miR-149 Suppresses the Proliferation and Metastasis of Human Gastric Cancer Cells by Targeting FOXC1.
BioMed research international
Li D,Zhang Y,Li Y,Wang X,Wang F,Du J,Zhang H,Shi H,Wang Y,Gao Y,Feng Y,Yan J,Xue Y,Yang Y,Zhang J
Wed Jan 19 00:00:00 EST 2022
Silent information regulator 2 promotes clear cell renal cell carcinoma progression through deacetylation and small ubiquitin-related modifier 1 modification of glucose 6-phosphate dehydrogenase.
Cancer science
Ni Y,Yang Z,Agbana YL,Bai H,Wang L,Yang L,Yi Z,Cheng J,Zhang Q,Kuang Y,Zhu Y
Fri Oct 01 00:00:00 EDT 2021
Low-dose exposure to black carbon significantly increase lung injury of cadmium by promoting cellular apoptosis.
Ecotoxicology and environmental safety
Wang L,Bao S,Liu X,Wang F,Zhang J,Dang P,Wang F,Li B,Lin Y
Mon Nov 01 00:00:00 EDT 2021
CSNK2A1-mediated phosphorylation of HMGA2 modulates cisplatin resistance in cervical cancer.
FEBS open bio
Shi Z,Wu D,Xu H,Yang J,Sun X
Sun Aug 01 00:00:00 EDT 2021
High-Risk HPV16 E6 Activates the cGMP/PKG Pathway Through Glycosyltransferase ST6GAL1 in Cervical Cancer Cells.
Frontiers in oncology
Wang J,Liu G,Liu M,Cai Q,Yao C,Chen H,Song N,Yuan C,Tan D,Hu Y,Xiang Y,Xiang T
Wed Nov 08 00:00:00 EST 2023
Knockdown of enhancer of rudimentary homolog expression attenuates proliferation, cell cycle and apoptosis of melanoma cells.
Melanoma research
Xiao M,Tang N,Yan Y,Li Z,Shi S,He S,Chen Z,Cao K,Chen J,Zhou J,Chen X
Sun Aug 01 00:00:00 EDT 2021
The Long-Term DEHP Exposure Confers Multidrug Resistance of Triple-Negative Breast Cancer Cells through ABC Transporters and Intracellular ROS.
Antioxidants (Basel, Switzerland)
Jadhao M,Tsai EM,Yang HC,Chen YF,Liang SS,Wang TN,Teng YN,Huang HW,Wang LF,Chiu CC
Fri Jun 11 00:00:00 EDT 2021
Ganoderma lucidum Spore Polysaccharide Inhibits the Growth of Hepatocellular Carcinoma Cells by Altering Macrophage Polarity and Induction of Apoptosis.
Journal of immunology research
Song M,Li ZH,Gu HS,Tang RY,Zhang R,Zhu YL,Liu JL,Zhang JJ,Wang LY
Thu Nov 11 00:00:00 EST 2021
Selonsertib Alleviates the Progression of Rat Osteoarthritis: An in vitro and in vivo Study.
Frontiers in pharmacology
Yan J,Zhang Y,Sheng G,Ni B,Xiao Y,Wang S,Wang T,Ma Y,Wang H,Wu H,Tu C
Fri Jul 30 00:00:00 EDT 2021
miR-126 Controls the Apoptosis and Proliferation of Immature Porcine Sertoli Cells by Targeting the PIK3R2 Gene through the PI3K/AKT Signaling Pathway.
Animals : an open access journal from MDPI
Tang X,Chen Y,Luo H,Bian Q,Weng B,Yang A,Chu D,Ran M,Chen B
Fri Jul 30 00:00:00 EDT 2021
Expression and purification of a recombinant ELRL-MAP30 with dual-targeting anti-tumor bioactivity.
Protein expression and purification
Chen WW,Zhang HR,Huang ZG,Zhou ZY,Lou QW,Jiang XY,Zhu ZH
Wed Sep 01 00:00:00 EDT 2021
The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML.
Blood cancer journal
Qiao X,Ma J,Knight T,Su Y,Edwards H,Polin L,Li J,Kushner J,Dzinic SH,White K,Wang J,Lin H,Wang Y,Wang L,Wang G,Taub JW,Ge Y
Mon Jun 07 00:00:00 EDT 2021
PGC1α regulates mitochondrial oxidative phosphorylation involved in cisplatin resistance in ovarian cancer cells via nucleo-mitochondrial transcriptional feedback.
Experimental cell research
Shen L,Zhou L,Xia M,Lin N,Ma J,Dong D,Sun L
Fri Jan 01 00:00:00 EST 2021
The biological effect of cobalt chloride mimetic-hypoxia on nucleus pulposus cells and the comparability with physical hypoxia in vitro.
Frontiers in bioscience (Landmark edition)
Gao XX,Liu CH,Hu ZL,Li HY,Chang X,Li YY,Zhang YY,Zhai Y,Li CQ
Sat Oct 30 00:00:00 EDT 2021
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
Oncology reports
Zong B,Sun L,Peng Y,Wang Y,Yu Y,Lei J,Zhang Y,Guo S,Li K,Liu S
Thu Jul 01 00:00:00 EDT 2021
Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line.
Life sciences
Yang W,Liu J,Hou L,Chen Q,Liu Y
Fri Jan 15 00:00:00 EST 2021
CLEC12B suppresses lung cancer progression by inducing SHP-1 expression and inactivating the PI3K/AKT signaling pathway.
Experimental cell research
Chi D,Wang D,Zhang M,Ma H,Chen F,Sun Y
Wed Dec 15 00:00:00 EST 2021
Interleukin-17 aggravates right ventricular remodeling via activating STAT3 under both normoxia and hypoxia.
BMC cardiovascular disorders
Huang J,Zhang W,Zhang CL,Wang L
Fri May 21 00:00:00 EDT 2021
Interleukin-17 aggravates right ventricular remodeling via activating STAT3 under both normoxia and hypoxia.
BMC cardiovascular disorders
Huang J,Zhang W,Zhang CL,Wang L
Fri May 21 00:00:00 EDT 2021
Interleukin-17 aggravates right ventricular remodeling via activating STAT3 under both normoxia and hypoxia.
BMC cardiovascular disorders
Huang J,Zhang W,Zhang CL,Wang L
Fri May 21 00:00:00 EDT 2021
TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhong BR,Zhou GF,Song L,Wen QX,Deng XJ,Ma YL,Hu LT,Chen GJ
Sat May 01 00:00:00 EDT 2021
Grape seed proanthocyanidins protect PC12 cells from hydrogen peroxide-induced damage via the PI3K/AKT signaling pathway.
Neuroscience letters
He X,Guo X,Ma Z,Li Y,Kang J,Zhang G,Gao Y,Liu M,Chen H,Kang X
Sat Apr 17 00:00:00 EDT 2021
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Journal of cellular and molecular medicine
Gao L,Nie X,Gou R,Hu Y,Dong H,Li X,Lin B
Wed Dec 01 00:00:00 EST 2021
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Frontiers in medicine
Gu L,Ren F,Fang X,Yuan L,Liu G,Wang S
Tue Jul 13 00:00:00 EDT 2021
Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.
Nutrition and cancer
Sun H,Zhang T,Liu R,Cao W,Zhang Z,Liu Z,Qian W,Wang D,Yu D,Zhong C
Wed Sep 08 00:00:00 EDT 2021
Disruption of Gprasp2 down-regulates Hedgehog signaling and leads to apoptosis in auditory cells.
Biochemical and biophysical research communications
Lu Y,Zhang M,Wei Q,Chen Z,Xing G,Yao J,Cao X
Fri Oct 15 00:00:00 EDT 2021
Protective effect of procyanidin A-type dimers against H2O2-induced oxidative stress in prostate DU145 cells through the MAPKs signaling pathway.
Life sciences
Yan F,Chen L,Chen W,Zhao L,Lu Q,Liu R
Mon Feb 01 00:00:00 EST 2021
Loss of Camk2n1 aggravates cardiac remodeling and malignant ventricular arrhythmia after myocardial infarction in mice via NLRP3 inflammasome activation.
Free radical biology & medicine
Wei Z,Fei Y,Wang Q,Hou J,Cai X,Yang Y,Chen T,Xu Q,Wang Y,Li YG
Sat May 01 00:00:00 EDT 2021
Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities.
European journal of medicinal chemistry
Wang S,Zhang RH,Zhang H,Wang YC,Yang D,Zhao YL,Yan GY,Xu GB,Guan HY,Zhou YH,Cui DB,Liu T,Li YJ,Liao SG,Zhou M
Fri Oct 15 00:00:00 EDT 2021
A novel circular RNA (hsa_circ_0059930)-mediated miRNA-mRNA axis in the lipopolysaccharide-induced acute lung injury model of MRC-5 cells.
Bioengineered
Han J,Li S,Feng Y,He Y,Hong W,Ye Z
Wed Dec 01 00:00:00 EST 2021
Elevated Secretion of Aldosterone Increases TG/HDL-C Ratio and Potentiates The Ox-LDL-Induced Dysfunction of HUVEC.
Cell journal
Zhang Q,Pan Y,Ma X,Yang H,Chang J,Hong L,Yan H,Zhang SH
Thu Apr 01 00:00:00 EDT 2021
Downregulation of miR-135b-5p Suppresses Progression of Esophageal Cancer and Contributes to the Effect of Cisplatin.
Frontiers in oncology
Di Y,Jiang Y,Shen X,Liu J,Gao Y,Cai H,Sun X,Ning D,Liu B,Lei J,Jin S
Tue Nov 07 00:00:00 EST 2023
Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration.
Oxidative medicine and cellular longevity
Wang B,Ke W,Wang K,Li G,Ma L,Lu S,Xiang Q,Liao Z,Luo R,Song Y,Hua W,Wu X,Zhang Y,Zeng X,Yang C
Thu Sep 09 00:00:00 EDT 2021
Limonin ameliorates dextran sulfate sodium-induced chronic colitis in mice by inhibiting PERK-ATF4-CHOP pathway of ER stress and NF-κB signaling.
International immunopharmacology
Song C,Chen J,Li X,Yang R,Cao X,Zhou L,Zhou Y,Ying H,Zhang Q,Sun Y
Fri Jan 01 00:00:00 EST 2021
Transcription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney disease.
Free radical biology & medicine
Gu X,Liu Y,Wang N,Zhen J,Zhang B,Hou S,Cui Z,Wan Q,Feng H
Sat Feb 20 00:00:00 EST 2021
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
Bioorganic & medicinal chemistry
Qin J,Sun X,Ma Y,Cheng Y,Ma Q,Jing W,Qu S,Liu L
Fri Dec 31 00:00:00 EST 2021
Chloroquine enhances catalpol's ability to promote apoptosis by inhibiting catalpol's autophagy-promoting effect on gastric cancer.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology
Sun F,Wang Z,Wang X
Wed Dec 08 00:00:00 EST 2021
Temperature Variability Does Not Attenuate the Beneficial Effects of Therapeutic Hypothermia on Cellular Apoptosis and Endoplasmic Reticulum Stress in the Cerebral Cortex of a Swine Cardiac Arrest Model.
Neurocritical care
Zhang B,Gu Q,Chen X,You Y,Chen M,Qian Y,Chen Y,Yu W
Tue Jun 01 00:00:00 EDT 2021
Hyperoside ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Sun K,Luo J,Jing X,Xiang W,Guo J,Yao X,Liang S,Guo F,Xu T
Fri Jan 01 00:00:00 EST 2021
Neuroprotective effects of bone marrow Sca-1+ cells against age-related retinal degeneration in OPTN E50K mice.
Cell death & disease
Liu X,Hou M,Zhang S,Zhao Y,Wang Q,Jiang M,Du M,Shao Z,Yuan H
Tue Jun 15 00:00:00 EDT 2021
miR-142-3p and HMGB1 Are Negatively Regulated in Proliferation, Apoptosis, Migration, and Autophagy of Cartilage Endplate Cells.
Cartilage
Wang B,Ji D,Xing W,Li F,Huang Z,Zheng W,Xue J,Zhu Y,Yang X
Wed Dec 01 00:00:00 EST 2021
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
International journal of molecular medicine
Dai W,Wang M,Wang P,Wen J,Wang J,Cha S,Xiao X,He Y,Shu R,Bai D
Mon Feb 01 00:00:00 EST 2021
HIF-1/AKT Signaling-Activated PFKFB2 Alleviates Cardiac Dysfunction and Cardiomyocyte Apoptosis in Response to Hypoxia.
International heart journal
Gao J,Feng W,Lv W,Liu W,Fu C
Tue Mar 30 00:00:00 EDT 2021
Microarray analysis reveals a potential role of lncRNA expression in remote ischemic preconditioning in myocardial ischemia-reperfusion injury.
American journal of translational research
Lou Z,Wu W,Chen R,Xia J,Shi H,Ge H,Xue J,Wang H,Lin Z,Chu M,Zhao Q
Fri Nov 10 00:00:00 EST 2023
AG490 protects cerebral ischemia/reperfusion injury via inhibiting the JAK2/3 signaling pathway.
Brain and behavior
Fan L,Zhou L
Fri Jan 01 00:00:00 EST 2021
sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis.
Stem cell research & therapy
Zhao Y,Yang X,Li S,Zhang B,Li S,Wang X,Wang Y,Jia C,Chang Y,Wei W
Sat Oct 09 00:00:00 EDT 2021
Chlorogenic acid enhances autophagy by upregulating lysosomal function to protect against SH-SY5Y cell injury induced by H2O2.
Experimental and therapeutic medicine
Gao LJ,Dai Y,Li XQ,Meng S,Zhong ZQ,Xu SJ
Sat May 01 00:00:00 EDT 2021
CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression.
Oncogenesis
Liao Q,Ren Y,Yang Y,Zhu X,Zhi Y,Zhang Y,Chen Y,Ding Y,Zhao L
Fri Dec 03 00:00:00 EST 2021
WNK3 Promotes Neuronal Survival after Traumatic Brain Injury in Rats.
Neuroscience
Zhu J,Lin X,Chen C,Tan H,Gao Y,Li D,Chen G
Sun Nov 21 00:00:00 EST 2021
Endophilin A2-mediated alleviation of endoplasmic reticulum stress-induced cardiac injury involves the suppression of ERO1α/IP3R signaling pathway.
International journal of biological sciences
Liu Y,Hu R,Shen H,Mo Q,Wang X,Zhang G,Li S,Liang G,Hou N,Luo J
Fri Feb 10 00:00:00 EST 2023
LncRNA CD27-AS1 promotes acute myeloid leukemia progression through the miR-224-5p/PBX3 signaling circuit.
Cell death & disease
Tao Y,Zhang J,Chen L,Liu X,Yao M,Zhang H
Tue May 18 00:00:00 EDT 2021
IL-22 ameliorated cardiomyocyte apoptosis in cardiac ischemia/reperfusion injury by blocking mitochondrial membrane potential decrease, inhibiting ROS and cytochrome C.
Biochimica et biophysica acta. Molecular basis of disease
Che Y,Tian Y,Chen R,Xia L,Liu F,Su Z
Wed Sep 01 00:00:00 EDT 2021
The Phenoxyphenol Compound diTFPP Mediates Exogenous C2-Ceramide Metabolism, Inducing Cell Apoptosis Accompanied by ROS Formation and Autophagy in Hepatocellular Carcinoma Cells.
Antioxidants (Basel, Switzerland)
Chang WT,Bow YD,Chen YC,Li CY,Chen JY,Chu YC,Teng YN,Li RN,Chiu CC
Fri Mar 05 00:00:00 EST 2021
α-Solanine Inhibits Proliferation, Invasion, and Migration, and Induces Apoptosis in Human Choriocarcinoma JEG-3 Cells In Vitro and In Vivo.
Toxins
Gu T,Yuan W,Li C,Chen Z,Wen Y,Zheng Q,Yang Q,Xiong X,Yuan A
Sat Mar 13 00:00:00 EST 2021
Babao Dan Reverses Multiple-Drug Resistance in Gastric Cancer Cells via Triggering Apoptosis and Autophagy and Inhibiting PI3K/AKT/mTOR Signaling.
Evidence-based complementary and alternative medicine : eCAM
Zhao J,Lan W,Peng J,Guan B,Liu J,Zhang M,Zhan Z,Lin J
Tue Jul 27 00:00:00 EDT 2021
EphA2 overexpression reduces H2O2-induced damage of lens epithelial cells.
Genetics and molecular biology
Ji Q,Liu J,Wang G,Liu L,Zhong J
Sat Aug 14 00:00:00 EDT 2021
UHRF1 Knockdown Attenuates Cell Growth, Migration, and Invasion in Cutaneous Squamous Cell Carcinoma.
Cancer investigation
Li Q,Chu Z,Geng S
Fri Jan 01 00:00:00 EST 2021
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Oxidative medicine and cellular longevity
Wang Y,Wang J,Yang J,Kang J,Xue F,Chang S,Ji H,Zang H,Zhou X,Wang G,Fan W,Yan X,Guo J,Ren X,Tian J
Wed Jan 19 00:00:00 EST 2022
Rational design and synthesis of 6-aryl-6H-benzo[c]chromenes as non-steroidal progesterone receptor antagonists for use against cancers.
Bioorganic & medicinal chemistry
Qin J,Qu S,Zhu K,Cheng Y,Pan G,Jing W,Liu X,Sun X,Liu L
Mon Feb 15 00:00:00 EST 2021
Combined Treatment of Cinobufotalin and Gefitinib Exhibits Potent Efficacy against Lung Cancer.
Evidence-based complementary and alternative medicine : eCAM
Han Y,Ma R,Cao G,Liu H,He L,Tang L,Li H,Luo Q
Tue Jun 15 00:00:00 EDT 2021
WISP-1 induced by mechanical stress contributes to fibrosis and hypertrophy of the ligamentum flavum through Hedgehog-Gli1 signaling.
Experimental & molecular medicine
Sun C,Ma Q,Yin J,Zhang H,Liu X
Tue Jun 01 00:00:00 EDT 2021
PKM2 Is a Potential Diagnostic and Therapeutic Target for Retinitis Pigmentosa.
Disease markers
Zhu P,Yang Q,Li G,Chang Q
Tue Mar 01 00:00:00 EST 2022
Total Flavonoids of Chuju Decrease Oxidative Stress and Cell Apoptosis in Ischemic Stroke Rats: Network and Experimental Analyses.
Frontiers in neuroscience
Wang C,Chen H,Jiang HH,Mao BB,Yu H
Tue Dec 28 00:00:00 EST 2021
Delivery of Rapamycin by Liposomes Synergistically Enhances the Chemotherapy Effect of 5-Fluorouracil on Colorectal Cancer.
International journal of nanomedicine
Chen YQ,Zhu WT,Lin CY,Yuan ZW,Li ZH,Yan PK
Thu Jan 28 00:00:00 EST 2021
VHL regulates the sensitivity of clear cell renal cell carcinoma to SIRT4-mediated metabolic stress via HIF-1α/HO-1 pathway.
Cell death & disease
Tong Y,Kai J,Wang S,Yu Y,Xie S,Zheng H,Wang Y,Liu Y,Zhu K,Guan X,Guo L,Lu R
Wed Jun 16 00:00:00 EDT 2021
WAC, a novel GBM tumor suppressor, induces GBM cell apoptosis and promotes autophagy.
Medical oncology (Northwood, London, England)
Wang Y,Zhang S,Sun Q,Yuan F,Zhao L,Ye Z,Li Y,Wang R,Jiang H,Hu P,Tian D,Liu B
Tue Sep 28 00:00:00 EDT 2021
Valproic Acid Reduces Vasospasm through Modulation of Akt Phosphorylation and Attenuates Neuronal Apoptosis in Subarachnoid Hemorrhage Rats.
International journal of molecular sciences
Wu CH,Tsai YC,Tsai TH,Kuo KL,Su YF,Chang CH,Lin CL
Tue Jun 01 00:00:00 EDT 2021
Upregulation of thioredoxin contributes to inhibiting diabetic hearing impairment.
Diabetes research and clinical practice
Ren X,Lv J,Fu Y,Zhang N,Zhang C,Dong Z,Chudhary M,Zhong S,Kong L,Kong H
Wed Sep 01 00:00:00 EDT 2021
OSU-03012 Disrupts Akt Signaling and Prevents Endometrial Carcinoma Progression in vitro and in vivo.
Drug design, development and therapy
Ding L,Ren C,Yang L,Wu Z,Li F,Jiang D,Zhu Y,Lu J
Thu Nov 04 00:00:00 EDT 2021
Anti-CD19 mAb modified mesoporous titanium dioxide as exclusively targeting vector for efficient B-lymphoblastic leukemia therapy.
Journal of pharmaceutical sciences
Li S,Zhang L,Li M,Huang J,Cui B,Jia J,Guo Z,Ma K,Cui C
Thu Jul 01 00:00:00 EDT 2021
Characterization of Kinesin Family Member 2C as a Proto-Oncogene in Cervical Cancer.
Frontiers in pharmacology
Yang J,Wu Z,Yang L,Jeong JH,Zhu Y,Lu J,Wang B,Wang N,Wang Y,Shen K,Li R
Wed Feb 16 00:00:00 EST 2022
Efficient Delivery of Chlorin e6 by Polyglycerol-Coated Iron Oxide Nanoparticles with Conjugated Doxorubicin for Enhanced Photodynamic Therapy of Melanoma.
Molecular pharmaceutics
Li TF,Xu HZ,Xu YH,Yu TT,Tang JM,Li K,Wang C,Peng XC,Li QR,Sang XY,Zheng MY,Liu Y,Zhao L,Chen X
Mon Sep 06 00:00:00 EDT 2021
Coaction of hepatic thioredoxin and glutathione systems in iron overload-induced oxidative stress.
Journal of biochemical and molecular toxicology
Sönmez Aydın F,Hukkamlı B,Budak H
Thu Apr 01 00:00:00 EDT 2021
Expression of long-chain noncoding RNA GAS5 in osteoarthritis and its effect on apoptosis and autophagy of osteoarthritis chondrocytes.
Histology and histopathology
Ji Q,Qiao X,Liu Y,Wang D
Thu Apr 01 00:00:00 EDT 2021