Invitrogen

BBS1 Polyclonal Antibody

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BBS1 Antibody in Immunocytochemistry (ICC/IF) — Immunocytochemichal analysis of BBS1 in HepG2 cells using a Polyclonal antibody (Product # PA5-113189) at a dilution of 1:100. An Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L) secondary antibdoy was used.

BBS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunocytochemical analysis of paraffin-embeded BBS1 in human kidney tissue using a BBS1 Polyclonal antibody (Product # PA5-113189) at a dilution of 1:100.

BBS1 Antibody in Western Blot (WB) — Western Blot analysis of BBS1 in mouse lung tissue using a BBS1 polyclonal antibody (Product # PA5-113189) at a concentration of 1 µg/ml. A goat anti rabbit polyclonal secondary antibody was used at a dilution of 1:50,000.

Product Details

PA5-113189

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:5,000	-
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	1:50-1:200	-
ELISA (ELISA)	Assay-dependent	-

Product Specifications
Species Reactivity	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Recombinant Human Bardet-Biedl syndrome 1 protein (217-417AA) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	2 mg/mL
Purification	Protein G
Storage buffer	PBS, pH 7.4, with 50% glycerol
Contains	0.03% ProClin 300
Storage conditions	-20°C or -80°C if preferred
RRID	AB_2867923

Target Information

Mutations in this gene have been observed in patients with the major form (type 1) of Bardet-Biedl syndrome. The encoded protein may play a role in eye, limb, cardiac and reproductive system development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Bardet-Biedl syndrome 1 homolog; Bardet-Biedl syndrome 1 protein; Bardet-Biedl syndrome 1 protein homolog; BBS2-like protein 2

Gene Aliases: AI451249; BBS1; BBS2L2; D19Ertd609e

UniProt ID: (Human) Q8NFJ9, (Mouse) Q3V3N7

Entrez Gene ID: (Human) 582, (Mouse) 52028

Function(s)

retina homeostasis visual perception nonmotile primary cilium assembly cilium assembly Golgi to plasma membrane protein transport photoreceptor cell maintenance response to stimulus protein localization to cilium microtubule cytoskeleton organization neuron migration sensory perception of smell protein localization photoreceptor cell morphogenesis fertilization dendrite development ventricular system development striatum development hippocampus development cerebral cortex development adult behavior intraciliary retrograde transport olfactory behavior hormone metabolic process cellular lipid metabolic process brain morphogenesis cartilage development cilium morphogenesis regulation of cilium beat frequency involved in ciliary motility neural precursor cell proliferation

Process(es)

RNA polymerase II repressing transcription factor binding patched binding smoothened binding protein binding receptor binding phosphoprotein binding

BBS1 Polyclonal Antibody

Product Details

PA5-113189

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

ELISA (ELISA)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

RRID

Target Information

References (0)

Bioinformatics

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