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Invitrogen
BBS4 Polyclonal Antibody
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Product Details
PA5-58783
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human BBS4. Recombinant protein control fragment (Product #RP-98098).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2638489
Product Specific Information
Immunogen sequence: TQFPVSTESQ KPRQKKAPEF PILEKQNWLI HLHYIRKDYE ACKAVIKEQL QETQGLCEYA IYVQALIFRL EGNIQESL
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.
Target Information
BBS4 contains tetratricopeptide repeats (TPR), similar to O-linked N-acetyglucosamine transferase. Mutations in the gene encoding this protein have been observed in patients with Bardet-Biedl syndrome type 4. BBS4 may play a role in pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bardet-Biedl syndrome 4 protein; BBSome complex member BBS4
Gene Aliases: BBS4
UniProt ID: (Human) Q96RK4
Entrez Gene ID: (Human) 585
microtubule cytoskeleton organization
mitotic cytokinesis
neuron migration
neural tube closure
retina homeostasis
heart looping
negative regulation of systemic arterial blood pressure
spermatid development
visual perception
sensory perception of smell
negative regulation of gene expression
protein transport
dendrite development
regulation of lipid metabolic process
ventricular system development
striatum development
hippocampus development
cerebral cortex development
adult behavior
negative regulation of actin filament polymerization
melanosome transport
regulation of cytokinesis
protein localization to organelle
negative regulation of GTPase activity
microtubule anchoring at centrosome
nonmotile primary cilium assembly
social behavior
photoreceptor cell outer segment organization
negative regulation of appetite by leptin-mediated signaling pathway
positive regulation of multicellular organism growth
cilium assembly
fat cell differentiation
photoreceptor cell maintenance
positive regulation of cilium assembly
retinal rod cell development
intracellular transport
brain morphogenesis
sensory processing
centrosome organization
maintenance of protein location in nucleus
regulation of stress fiber assembly
cilium morphogenesis
regulation of cilium beat frequency involved in ciliary motility
face development
fat pad development
protein localization to cilium
protein localization to centrosome
regulation of nonmotile primary cilium assembly
protein localization to photoreceptor outer segment
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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