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BBS8/TTC8 Antibody (BS-11510R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Mouse stomach; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with BBS8/TTC8 Polyclonal Antibody, Unconjugated (bs-11510R) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 2... View More
Product Details
BS-11510R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human BBS8, amino acids 251-330.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 1% BSA
Contains
0.09% sodium azide
Storage conditions
-20°C
Target Information
This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bardet-Biedl syndrome 8 protein; Bardet-Biedl syndrome 8 protein homolog; Bardet-Biedl syndrome type 8; Tetratricopeptide repeat protein 8; TPR repeat protein 8
Gene Aliases: 0610012F22Rik; AV001447; BBS8; RP51; TTC8
UniProt ID: (Human) Q8TAM2, (Mouse) Q8VD72
Entrez Gene ID: (Human) 123016, (Rat) 299246, (Mouse) 76260
axon guidance
sensory perception of smell
biological_process
olfactory bulb development
regulation of protein localization
nonmotile primary cilium assembly
multicellular organism growth
cilium assembly
fat cell differentiation
establishment of anatomical structure orientation
regulation of stress fiber assembly
camera-type eye photoreceptor cell differentiation
renal tubule development
protein transport
sensory processing
transport
cell projection organization
negative regulation of GTPase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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