Immunogen sequence: KTLELRVAYL DPLELSEGKV LSLPLNSSAV VNCSVHGLPT PALRWTKDST PLGDGPMLSL SSITFDSNGT YVCEASLPTV PVLSRTQNFT LLVQGSPELK TAEIEPKADG SWREGDEVTL ICSARGHPDP KLSWSQLGGS PAEPIPGRQG WVSSSLTLKV TSALSRDGIS CEASNPHGNK RHVFHFGTVS PQTSQA; Positive Samples: Mouse lung; Cellular Location: Membrane, Single-pass type I membrane protein
Lutheran blood group glycoprotein is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five, N-terminus, extracellular immunoglobulin domains, a single transmembrane domain, and a short, C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Auberger b antigen; B-CAM cell surface glycoprotein; Basal cell adhesion molecule; CD239; Lutheran antigen; Lutheran blood group; lutheran glycoprotein
Gene Aliases: 1200005K12Rik; B-CAM; Bcam; Gplu; Lu
UniProt ID: (Mouse) Q9R069
Entrez Gene ID: (Mouse) 57278