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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 532-550 of human BCAS1/NABC1.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-5 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-10886 detects BCAS1 / NABC1 in human samples.
PA1-10886 has been successfully used in Western blot procedures. A band of approximately 60 kDa is detected by Western blot; however, prtein dimerization may occur.
PA1-10886 immunogen is a synthetic peptide corresponding to residues 532-550 of human BCAS1/NABC1.
Breast Carcinoma Amplified Sequence 1 (BCAS1), also known as Novel Amplified in Breast Cancer 1 (NABC1) was isolated from a region at 20q13 and is amplified in several tumor types. It is associated with more aggressive tumor phenotypes. BCAS1/NABC1 is highly expressed in some, but not all, breast cancer cell lines and in some breast tumors at 20q13.2. The BCAS1/NABC1 gene is predicted to encode a protein of 584 amino acids with no significant homology to other proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.