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Product Details
PA5-96622
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 674-913 of human BCAS3 (NP_0601493)
Conjugate
Form
Liquid
Concentration
0.54 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808424
Product Specific Information
Immunogen sequence: LAGLVPPGSP GPITRHGSYD SLASDHSGQE DEEWLSQVEI VTHTGPHRRL WMGPQFQFKT IHPSGQTTVI SSSSSVLQSH GPSDTPQPLL DFDTDDLDLN SLRIQPVRSD PVSMPGSSRP VSDRRGVSTV IDAASGTFDR SVTLLEVCGS WPEGFGLRHM SSMEHTEEGL RERLADAMAE SPSRDVVGSG TELQREGSIE TLSNSSGSTS GSIPRNFDGY RSPLPTNESQ PLSLFPTGFP; Positive Samples: HeLa, BT474, Rat brain; Cellular Location: Cytoplasm, Nucleus, cytoskeleton
Target Information
BCAS3 is physically associated with histone H3 and histone acetyltransferase complex protein P/CAF (p300/CBP-associated factor) and possesses histone acetyltransferase activity. In breast cancer, several chromosomal sites frequently undergo amplification, implicating the location of genes important for tumor development and progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BCAS3 microtubule associated cell migration factor; BCAS4/BCAS3 fusion; breast carcinoma amplified sequence 3; breast carcinoma amplified sequence 4/3 fusion protein; Breast carcinoma-amplified sequence 3; Breast carcinoma-amplified sequence 3 homolog; GAOB1; K20D4; Maab1 protein; metastasis associated antigen of breast cancer; protein Maab1; Protein rudhira; Rudhira
Gene Aliases: 1500019F07Rik; 2610028P08Rik; AU021018; BC028339; BCAS3; GAOB1; K20D4; MAAB; RGD1560788; rudhira
UniProt ID: (Human) Q9H6U6, (Mouse) Q8CCN5
Entrez Gene ID: (Human) 54828, (Mouse) 192197, (Rat) 363662
angiogenesis
transcription, DNA-templated
Golgi organization
positive regulation of endothelial cell migration
vesicle-mediated transport
microtubule organizing center organization
negative regulation of GTPase activity
tube formation
response to starvation
positive regulation of catalytic activity
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
positive regulation of filopodium assembly
negative regulation of focal adhesion assembly
cellular response to estrogen stimulus
positive regulation of intracellular protein transport
activation of GTPase activity
regulation of establishment of cell polarity
positive regulation of actin cytoskeleton reorganization
regulation of transcription, DNA-templated
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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