Immunogen sequence: LAGLVPPGSP GPITRHGSYD SLASDHSGQE DEEWLSQVEI VTHTGPHRRL WMGPQFQFKT IHPSGQTTVI SSSSSVLQSH GPSDTPQPLL DFDTDDLDLN SLRIQPVRSD PVSMPGSSRP VSDRRGVSTV IDAASGTFDR SVTLLEVCGS WPEGFGLRHM SSMEHTEEGL RERLADAMAE SPSRDVVGSG TELQREGSIE TLSNSSGSTS GSIPRNFDGY RSPLPTNESQ PLSLFPTGFP; Positive Samples: HeLa, BT474, Rat brain; Cellular Location: Cytoplasm, Nucleus, cytoskeleton
BCAS3 is physically associated with histone H3 and histone acetyltransferase complex protein P/CAF (p300/CBP-associated factor) and possesses histone acetyltransferase activity. In breast cancer, several chromosomal sites frequently undergo amplification, implicating the location of genes important for tumor development and progression.
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Protein Aliases: BCAS4/BCAS3 fusion; breast carcinoma amplified sequence 3; breast carcinoma amplified sequence 4/3 fusion protein; Breast carcinoma-amplified sequence 3; Breast carcinoma-amplified sequence 3 homolog; GAOB1; K20D4; Maab1 protein; metastasis associated antigen of breast cancer; protein Maab1; Protein rudhira; Rudhira
Gene Aliases: 1500019F07Rik; 2610028P08Rik; AU021018; BC028339; BCAS3; GAOB1; K20D4; MAAB; RGD1560788; rudhira