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|Tested species reactivity||Human , Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 77 and 367 of Human BCKDK|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28050 targets BCKDK in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-28050 immunogen is recombinant fragment corresponding to a region within amino acids 77 and 367 of Human BCKDK.
Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase; [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; BCKD-kinase; BCKDHKIN; branched chain alpha-ketoacid dehydrogenase kinase; branched-chain alpha-ketoacid dehydrogenase kinase; mitochondrial
AI327402; BCKDK; BCKDKD; BDK