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Proteintech
BCL11B Polyclonal Antibody
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Product Details
55414-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to BCL11B. The calculated molecular weight of BCL11B is 95 kDa, but modified BCL11B protein is about 116 kDa.
Target Information
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: B cell CLL/lymphoma 11B; B-cell CLL/lymphoma 11B; B-cell CLL/lymphoma 11B (zinc finger protein); B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein; B-cell leukemia/lymphoma 11B; B-cell lymphoma/leukaemia 11B; B-cell lymphoma/leukemia 11B; BAF chromatin remodeling complex subunit BCL11B; BCL-11B; BCL11B, BAF complex component; BCL11B/TRDC fusion; COUP-TF interacting protein 2; COUP-TF-interacting protein 2; hRit1; mRit1; Radiation-induced tumor suppressor gene 1 protein; zinc f; zinc finger protein hRit1 alpha
Gene Aliases: 9130430L19Rik; AI604821; ATL1; ATL1-alpha; ATL1-beta; ATL1-delta; ATL1-gamma; B630002E05Rik; BCL-11B; BCL11B; CTIP-2; CTIP2; hRIT1-alpha; IDDFSTA; IMD49; RIT1; SMARCM2; ZNF856B
UniProt ID: (Human) Q9C0K0, (Mouse) Q99PV8
Entrez Gene ID: (Human) 64919, (Mouse) 58208
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
metal ion binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
nucleic acid binding
DNA-binding transcription factor
zinc finger transcription factor
C2H2 zinc finger transcription factor
gene-specific transcriptional regulator
keratinocyte development
epithelial cell morphogenesis
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
apoptotic process
axonogenesis
negative regulation of cell proliferation
post-embryonic development
regulation of gene expression
regulation of keratinocyte proliferation
regulation of lipid metabolic process
striatal medium spiny neuron differentiation
commitment of neuronal cell to specific neuron type in forebrain
central nervous system neuron differentiation
post-embryonic camera-type eye development
T cell differentiation in thymus
T cell receptor V(D)J recombination
hematopoietic stem cell migration
odontogenesis of dentin-containing tooth
positive T cell selection
skin development
regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
alpha-beta T cell differentiation
thymus development
T cell apoptotic process
negative regulation of T cell apoptotic process
thymocyte apoptotic process
negative regulation of thymocyte apoptotic process
olfactory bulb axon guidance
lymphoid lineage cell migration into thymus
transcription, DNA-templated
regulation of transcription, DNA-templated
negative regulation of apoptotic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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