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FIGURE: 1 / 3
Antibody detects endogenous levels of total BCL7A.
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B-cell CLL/lymphoma 7 protein family member A; B-cell CLL/lymphoma 7A; B-cell CLL/lymphoma-7; BCL 7
Gene Aliases: 4432415N06Rik; AI448316; BCL7; BCL7A
UniProt ID: (Human) Q4VC05, (Mouse) Q9CXE2
Entrez Gene ID: (Human) 605, (Mouse) 77045
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