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Proteintech
BCL7B Polyclonal Antibody
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Product Details
11740-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BCL7B Fusion Protein Ag2333 (1-202 aa encoded by BC000956)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
37.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSGRSVRAE TRSRAKDDIK KVMAAIEKVR KWEKKWVTVG DTSLRIFKWV PVTDSKEKEK SKSNSSAARE PNGFPSDASA NSSLLLEFQD ENSNQSSVSD VYQLKVDSST NSSPSPQQSE SLSPAHTSDF RTDDSQPPTL GQEILEEPSL PSSEVADEPP TLTKEEPVPL ETQVVEEEED SGAPPLKRFC VDQPTVPQTA SES (1-202 aa encoded by BC000956)
Target Information
Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1. Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation. May play a role in lung tumor development or progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: B-cell CLL/lymphoma 7 protein family member B; B-cell CLL/lymphoma 7B; BCL tumor suppressor 7B; BCL7B; BCL7B, BAF complex component; unnamed protein product
Gene Aliases: BCL7B; SMARCJ2
UniProt ID: (Human) Q9BQE9, (Mouse) Q921K9
Entrez Gene ID: (Human) 9275, (Rat) 368001, (Mouse) 12054
biological_process
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
apoptotic process
positive regulation of cell proliferation
Wnt signaling pathway
regulation of mitotic metaphase/anaphase transition
cell differentiation
negative regulation of cell differentiation
regulation of G0 to G1 transition
positive regulation of stem cell population maintenance
regulation of G1/S transition of mitotic cell cycle
positive regulation of double-strand break repair
regulation of nucleotide-excision repair
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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