Search
Invitrogen
BCO2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 3
BCO2 Antibody (PA5-104323) in ICC/IF
Immunofluorescent analysis of BCO2 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and BCO2 polyclonal antibody (Product # PA5-104323) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-104323
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human BCO2(Accession Q9BYV7), corresponding to amino acid residues L191-S241.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total BCO2.
Target Information
BCDO2 catalyzes the asymmetric oxidative cleavage of beta-carotene in carotene metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: b,b-carotene-9',10'-dioxygenase; B-diox-II; Beta,beta-carotene 9',10'-oxygenase; beta-carotene 9', 10'-dioxygenase 2; beta-carotene 9',10' oxygenase; beta-carotene 9',10'-dioxygenase 2; Beta-carotene dioxygenase 2; beta-diox-II; carotenoid 9',10' monooxygenase II; carotenoid 9',10' monoxygenase II; carotenoid-9',10'-cleaving dioxygenase; Carotenoid-cleaving dioxygenase, mitochondrial; unnamed protein product
Gene Aliases: Ab2-079; B-DIOX-II; BCDO2; Bcmo2; BCO2; CMO2
UniProt ID: (Human) Q9BYV7, (Mouse) Q99NF1
Entrez Gene ID: (Human) 83875, (Rat) 315644, (Mouse) 170752
beta-carotene 15,15'-monooxygenase activity
carotenoid dioxygenase activity
9,10 (9', 10')-carotenoid-cleaving dioxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
metal ion binding
dioxygenase activity
beta,beta-carotene-9',10'-cleaving oxygenase activity
structural constituent of ribosome
oxygenase
lipid metabolic process
carotenoid metabolic process
carotene metabolic process
carotene catabolic process
xanthophyll metabolic process
xanthophyll catabolic process
retinoic acid metabolic process
retinal metabolic process
regulation of mitochondrial membrane potential
lutein catabolic process
lycopene catabolic process
zeaxanthin catabolic process
regulation of reactive oxygen species metabolic process
translation
oxidation-reduction process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support