Product References
Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice.
American journal of physiology. Endocrinology and metabolism
Rome FI,Shobert GL,Voigt WC,Stagg DB,Puchalska P,Burgess SC,Crawford PA,Hughey CC
Sun Jan 01 00:00:00 EST 2023
Ketogenic diet modulates cardiac metabolic dysregulation in streptozocin-induced diabetic rats.
The Journal of nutritional biochemistry
Trang NN,Lee TW,Kao YH,Chao TF,Lee TI,Chen YJ
Sun Jan 01 00:00:00 EST 2023
Novel Prognostic Signatures of Hepatocellular Carcinoma Based on Metabolic Pathway Phenotypes.
Frontiers in oncology
Ye T,Lin L,Cao L,Huang W,Wei S,Shan Y,Zhang Z
Sat Jul 16 00:00:00 EDT 2022
Maternal use of methamphetamine induces sex-dependent changes in myocardial gene expression in adult offspring.
Physiological reports
Dague A,Chavva H,Brazeau DA,Denvir J,Rorabaugh BR
Tue Nov 01 00:00:00 EDT 2022
Ketone body oxidation increases cardiac endothelial cell proliferation.
EMBO molecular medicine
Weis EM,Puchalska P,Nelson AB,Taylor J,Moll I,Hasan SS,Dewenter M,Hagenmüller M,Fleming T,Poschet G,Hotz-Wagenblatt A,Backs J,Crawford PA,Fischer A
Thu Apr 07 00:00:00 EDT 2022
Ketogenic diet uncovers differential metabolic plasticity of brain cells.
Science advances
Düking T,Spieth L,Berghoff SA,Piepkorn L,Schmidke AM,Mitkovski M,Kannaiyan N,Hosang L,Scholz P,Shaib AH,Schneider LV,Hesse D,Ruhwedel T,Sun T,Linhoff L,Trevisiol A,Köhler S,Pastor AM,Misgeld T,Sereda M,Hassouna I,Rossner MJ,Odoardi F,Ischebeck T,de Hoz L,Hirrlinger J,Jahn O,Saher G
Fri Sep 16 00:00:00 EDT 2022
Ketone body β-hydroxybutyrate ameliorates colitis by promoting M2 macrophage polarization through the STAT6-dependent signaling pathway.
BMC medicine
Huang C,Wang J,Liu H,Huang R,Yan X,Song M,Tan G,Zhi F
Fri Apr 15 00:00:00 EDT 2022
Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction.
Molecular metabolism
Rome FI,Hughey CC
Fri Apr 01 00:00:00 EDT 2022
β-hydroxybutyrate reduces reinstatement of cocaine conditioned place preference through hippocampal CaMKII-α β-hydroxybutyrylation.
Cell reports
Li H,Wan X,Wu Z,Zhou Y,Chen R,Xu W,Zhang J,Yang Z,Bai L,Zhang J,Qin F,Wang L,Chen Y,Jiang L,He Y,Wang X,Wei Q,Li S,Dai Y,Chen Y,Wang Y,Wang H,Tian J,Zhao Y,Cen X
Tue Nov 29 00:00:00 EST 2022
Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Tang M,Xu H,Huang H,Kuang H,Wang C,Li Q,Zhang X,Ge Y,Song M,Zhang X,Wang Z,Ma C,Kang J,Zhang W,Wang Y,Zhang B,Zhang X,Chen Y,Cong M,Melino G,Wang X,Zhou F,Sun Q,Shi H
Sat Oct 01 00:00:00 EDT 2022
Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Tang M,Xu H,Huang H,Kuang H,Wang C,Li Q,Zhang X,Ge Y,Song M,Zhang X,Wang Z,Ma C,Kang J,Zhang W,Wang Y,Zhang B,Zhang X,Chen Y,Cong M,Melino G,Wang X,Zhou F,Sun Q,Shi H
Sat Oct 01 00:00:00 EDT 2022
Deficiency of 3-hydroxybutyrate dehydrogenase (BDH1) in mice causes low ketone body levels and fatty liver during fasting.
Journal of inherited metabolic disease
Otsuka H,Kimura T,Ago Y,Nakama M,Aoyama Y,Abdelkreem E,Matsumoto H,Ohnishi H,Sasai H,Osawa M,Yamaguchi S,Mitchell GA,Fukao T
Tue Sep 01 00:00:00 EDT 2020
Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis.
Cell metabolism
Puchalska P,Martin SE,Huang X,Lengfeld JE,Daniel B,Graham MJ,Han X,Nagy L,Patti GJ,Crawford PA
Tue Feb 05 00:00:00 EST 2019
Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis.
Cell metabolism
Puchalska P,Martin SE,Huang X,Lengfeld JE,Daniel B,Graham MJ,Han X,Nagy L,Patti GJ,Crawford PA
Tue Feb 05 00:00:00 EST 2019
The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense.
JCI insight
Horton JL,Davidson MT,Kurishima C,Vega RB,Powers JC,Matsuura TR,Petucci C,Lewandowski ED,Crawford PA,Muoio DM,Recchia FA,Kelly DP
Thu Feb 21 00:00:00 EST 2019
Fenofibrate prevents skeletal muscle loss in mice with lung cancer.
Proceedings of the National Academy of Sciences of the United States of America
Goncalves MD,Hwang SK,Pauli C,Murphy CJ,Cheng Z,Hopkins BD,Wu D,Loughran RM,Emerling BM,Zhang G,Fearon DT,Cantley LC
Tue Jan 23 00:00:00 EST 2018
Fenofibrate prevents skeletal muscle loss in mice with lung cancer.
Proceedings of the National Academy of Sciences of the United States of America
Goncalves MD,Hwang SK,Pauli C,Murphy CJ,Cheng Z,Hopkins BD,Wu D,Loughran RM,Emerling BM,Zhang G,Fearon DT,Cantley LC
Tue Jan 23 00:00:00 EST 2018
Ketone body 3-hydroxybutyrate mimics calorie restriction via the Nrf2 activator, fumarate, in the retina.
Aging cell
Izuta Y,Imada T,Hisamura R,Oonishi E,Nakamura S,Inagaki E,Ito M,Soga T,Tsubota K
Thu Feb 01 00:00:00 EST 2018
Ketone body 3-hydroxybutyrate mimics calorie restriction via the Nrf2 activator, fumarate, in the retina.
Aging cell
Izuta Y,Imada T,Hisamura R,Oonishi E,Nakamura S,Inagaki E,Ito M,Soga T,Tsubota K
Thu Feb 01 00:00:00 EST 2018
Low ketolytic enzyme levels in tumors predict ketogenic diet responses in cancer cell lines in vitro and in vivo.
Journal of lipid research
Zhang J,Jia PP,Liu QL,Cong MH,Gao Y,Shi HP,Yu WN,Miao MY
Sun Apr 01 00:00:00 EDT 2018
Low ketolytic enzyme levels in tumors predict ketogenic diet responses in cancer cell lines in vitro and in vivo.
Journal of lipid research
Zhang J,Jia PP,Liu QL,Cong MH,Gao Y,Shi HP,Yu WN,Miao MY
Sun Apr 01 00:00:00 EDT 2018
Low ketolytic enzyme levels in tumors predict ketogenic diet responses in cancer cell lines in vitro and in vivo.
Journal of lipid research
Zhang J,Jia PP,Liu QL,Cong MH,Gao Y,Shi HP,Yu WN,Miao MY
Sun Apr 01 00:00:00 EDT 2018
Low ketolytic enzyme levels in tumors predict ketogenic diet responses in cancer cell lines in vitro and in vivo.
Journal of lipid research
Zhang J,Jia PP,Liu QL,Cong MH,Gao Y,Shi HP,Yu WN,Miao MY
Sun Apr 01 00:00:00 EDT 2018
CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs.
The Journal of cell biology
Schatton D,Pla-Martin D,Marx MC,Hansen H,Mourier A,Nemazanyy I,Pessia A,Zentis P,Corona T,Kondylis V,Barth E,Schauss AC,Velagapudi V,Rugarli EI
Mon Mar 06 00:00:00 EST 2017
CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs.
The Journal of cell biology
Schatton D,Pla-Martin D,Marx MC,Hansen H,Mourier A,Nemazanyy I,Pessia A,Zentis P,Corona T,Kondylis V,Barth E,Schauss AC,Velagapudi V,Rugarli EI
Mon Mar 06 00:00:00 EST 2017
Nutritional Ketosis Affects Metabolism and Behavior in Sprague-Dawley Rats in Both Control and Chronic Stress Environments.
Frontiers in molecular neuroscience
Brownlow ML,Jung SH,Moore RJ,Bechmann N,Jankord R
Tue Sep 29 00:00:00 EDT 2020
Nutritional Ketosis Affects Metabolism and Behavior in Sprague-Dawley Rats in Both Control and Chronic Stress Environments.
Frontiers in molecular neuroscience
Brownlow ML,Jung SH,Moore RJ,Bechmann N,Jankord R
Tue Sep 29 00:00:00 EDT 2020
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress.
Cell research
Huang D,Li T,Wang L,Zhang L,Yan R,Li K,Xing S,Wu G,Hu L,Jia W,Lin SC,Dang CV,Song L,Gao P,Zhang H
Sat Oct 01 00:00:00 EDT 2016
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress.
Cell research
Huang D,Li T,Wang L,Zhang L,Yan R,Li K,Xing S,Wu G,Hu L,Jia W,Lin SC,Dang CV,Song L,Gao P,Zhang H
Sat Oct 01 00:00:00 EDT 2016
Impairments of hepatic gluconeogenesis and ketogenesis in PPARα-deficient neonatal mice.
American journal of physiology. Endocrinology and metabolism
Cotter DG,Ercal B,d'Avignon DA,Dietzen DJ,Crawford PA
Tue Jul 15 00:00:00 EDT 2014
Impairments of hepatic gluconeogenesis and ketogenesis in PPARα-deficient neonatal mice.
American journal of physiology. Endocrinology and metabolism
Cotter DG,Ercal B,d'Avignon DA,Dietzen DJ,Crawford PA
Tue Jul 15 00:00:00 EDT 2014
Impact of peripheral ketolytic deficiency on hepatic ketogenesis and gluconeogenesis during the transition to birth.
The Journal of biological chemistry
Cotter DG,Ercal B,d'Avignon DA,Dietzen DJ,Crawford PA
Fri Jul 05 00:00:00 EDT 2013
Impact of peripheral ketolytic deficiency on hepatic ketogenesis and gluconeogenesis during the transition to birth.
The Journal of biological chemistry
Cotter DG,Ercal B,d'Avignon DA,Dietzen DJ,Crawford PA
Fri Jul 05 00:00:00 EDT 2013