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Immunogen sequence: ATSLYSPESI QAIAKKMWEE LPEVVRKDYG KKYFDEKIAK METYCSSGST DTSPVIDAVT HALTATTPYT RYHPMDYYWW LRMQIMTHL
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 91%.
This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and -3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: (R)-3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase (heart, mitochondrial); BDH; D-beta-hydroxybutyrate dehydrogenase, mitochondrial; MGC2723; MGC4347; MGC9788; Short chain dehydrogenase/reductase family 9C member 1; short chain dehydrogenase/reductase family 9C, member 1
Gene Aliases: BDH; BDH1; SDR9C1
UniProt ID: (Human) Q02338, (Rat) P29147
Entrez Gene ID: (Human) 622, (Rat) 117099
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