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Proteintech
BHLHE22 Polyclonal Antibody
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Product Details
25622-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Goat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BHLHE22 Fusion Protein Ag20966 (1-225 aa encoded by BC156671)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Amount
43.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MERGMHLGA AAAGEDDLFL HKSLSASTSK RLEAAFRSTP PGMDLSLAPP PRERPASSSS SPLGCFEPAD PEGAGLLLPP PGGGGGGSAG SGGGGGGGVG VPGLLVGSAG VGGDPSLSSL PAGAALCLKY GESASRGSVA ESSGGEQSPD DDSDGRCELV LRAGVADPRA SPGAGGGGAK AAEGCSNAHL HGGASVPPGG LGGGGGGGSS SGSSGGGGGS GSGSGG (1-225 aa encoded by B C156671)
Target Information
BHLHB5 inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. BHLHB5 despite the presence of an intact basic domain, does not bind to DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: basic helix-loop-helix (bHLH) gene, class B, beta3; basic helix-loop-helix domain containing, class B, 5; basic helix-loop-helix domain containing, class B5; bHLHb5; bHLHe22; Class B basic helix-loop-helix protein 5; Class E basic helix-loop-helix protein 22; Protein BETA3; trinucleotide repeat containing 20; Trinucleotide repeat-containing gene 20 protein; unnamed protein product
Gene Aliases: Beta3; Beta3a; BHLHB5; BHLHE22; CAGL85; TNRC20
UniProt ID: (Human) Q8NFJ8, (Mouse) Q8C6A8
Entrez Gene ID: (Human) 27319, (Mouse) 59058
nervous system development
sensory organ development
positive regulation of transcription from RNA polymerase II promoter
axon development
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
corpus callosum morphogenesis
cerebral cortex regionalization
central nervous system projection neuron axonogenesis
corticospinal tract morphogenesis
anterior commissure morphogenesis
neuron differentiation
negative regulation of transcription, DNA-templated
retinal bipolar neuron differentiation
retina morphogenesis in camera-type eye
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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