Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MAPAGRPGA KKGILERLES GEVVIGDGSF LITLEKRGYV KAGLWTPEAV IEHPDAVRQL HMEFLRAGSN VMQTFTFSAS EDNMESKWED VNAAACDLAR EVAGKGDALV AGGICQTSIY KYQKDEARIK KLFRQQLEVF AWKNVDFLIA EYFEHVEEAV WAVEVLKESD RPVAVTMCIG PEGDMHDITP GECAVRLVKA GASIVGVNCR FGPDTSLKTM ELMKEGLEWA GLKAHLMVQP LGFHAPDCGK EGFVDLPEYP FGLESRVATR WDIQKYAREA YNLGVRYIGG CCGFEPYHIR AIAEELAPER GFLPPASEKH GSWGSGLDMH TKPWIRARAR REYWENLLPA SGRPFCPSLS KPDF (1-363 aa encoded by BC020665)
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Betaine--homocysteine S-methyltransferase 2; betaine-homocysteine methyltransferase 2; S-methylmethionine--homocysteine S-methyltransferase BHMT2; SMM-hcy methyltransferase
Gene Aliases: BHMT2; C81077; D13Ucla2
UniProt ID: (Human) Q9H2M3, (Mouse) Q91WS4, (Rat) Q68FT5
Entrez Gene ID: (Human) 23743, (Mouse) 64918, (Rat) 365972
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