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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 94 and 363 of Human BHMT2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000-1:20,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30490 targets BHMT2 in IF and WB applications and shows reactivity with Human and mouse samples.
The PA5-30490 immunogen is recombinant fragment corresponding to a region within amino acids 94 and 363 of Human BHMT2.
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
betaine--homocysteine S-methyltransferase 2; betaine-homocysteine methyltransferase 2; S-methylmethionine--homocysteine S-methyltransferase BHMT2; SMM-hcy methyltransferase
BHMT2; C81077; D13Ucla2