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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the region surrounding amino acid 37 of human Bid.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 50% glycerol, 1% BSA|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||20-40 µg/ml|
|Immunoprecipitation (IP)||5-10 µg/ml|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-26454 detects Bid from human samples.
PA1-26454 has been successfully used in immunoprecipitation, and Western blot procedures.
The PA1-26454 immunogen is a synthetic peptide corresponding to the region surrounding amino acid 37 of human Bid.
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
apoptic death agonist; BH3-interacting domain death agonist; BID; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; desmocollin type 4; FP497; Human BID coding sequence; MGC15319; MGC42355; p22 BID