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Abnova
BIRC4 Polyclonal Antibody, MaxPab™
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Product Details
H00000331-D01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BIRC4 (NP_001158.2, 1 a.a. approximately 497 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MTFNSFEGSK TCVPADINKE EEFVEEFNRL KTFANFPSGS PVSASTLARA GFLYTGEGDT VRCFSCHAAV DRWQYGDSAV GRHRKVSPNC RFINGFYLEN SATQSTNSGI QNGQYKVENY LGSRDHFALD RPSETHADYL LRTGQVVDIS DTIYPRNPAM YSEEARLKSF QNWPDYAHLT PRELASAGLY YTGIGDQVQC FCCGGKLKNW EPCDRAWSEH RRHFPNCFFV LGRNLNIRSE SDAVSSDRNF PNSTNLPRNP SMADYEARIF TFGTWIYSVN KEQLARAGFY ALGEGDKVKC FHCGGGLTDW KPSEDPWEQH AKWYPGCKYL LEQKGQEYIN NIHLTHSLEE CLVRTTEKTP SLTRRIDDTI FQNPMVQEAI RMGFSFKDIK KIMEEKIQIS GSNYKSLEVL VADLVNAQKD SMQDESSQTS LQKEISTEEQ LRRLQEEKLC KICMDRNIAI VFVPCGHLVT CKQCAEAVDK CPMCYTVITF KQKIFMS
Target Information
ATP synthase is extremely conserved through evolution and can be found in plants, fungi, bacteria, and animals. The ATP synthase enzyme is a transmembrane protein responsible for driving the reversible reaction from ADP+ phosphate to ATP. This reaction is accomplished by a flux of protons across the membrane as a result of electron transfer. The ATP synthase protein has two main sections; the F1 ATP-ase (soluble) and the F0 ATP-ase (membrane embedded). The F1 section consists of the alpha, beta, gamma, delta, and epsilon subunits. While the F0 consists of a, b, and c subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Baculoviral IAP repeat-containing protein 4; BIR4; E3 ubiquitin-protein ligase XIAP; HILP; IAP-3; IAP-like protein; IAP-like protein 1; ILP; Inhibitor of apoptosis protein 3; RING-type E3 ubiquitin transferase XIAP; RP1-315G1.5; unnamed protein product; X-linked IAP; X-linked inhibitor of apoptosis protein; X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
Gene Aliases: API3; BIRC4; hIAP-3; hIAP3; IAP-3; IAP3; ILP1; MIHA; XIAP; XLP2
UniProt ID: (Human) P98170
Entrez Gene ID: (Human) 331
ubiquitin-protein transferase activity
cysteine-type endopeptidase inhibitor activity
protein binding
zinc ion binding
transferase activity
peptidase inhibitor activity
identical protein binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
metal ion binding
ubiquitin protein ligase activity
protein serine/threonine kinase binding
ubiquitin-dependent protein catabolic process
apoptotic process
cellular response to DNA damage stimulus
I-kappaB kinase/NF-kappaB signaling
negative regulation of tumor necrosis factor-mediated signaling pathway
Wnt signaling pathway
regulation of BMP signaling pathway
positive regulation of protein ubiquitination
negative regulation of type I interferon production
positive regulation of type I interferon production
response to lipopolysaccharide
p38MAPK cascade
defense response to bacterium
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
regulation of innate immune response
positive regulation of JNK cascade
regulation of inflammatory response
neuron apoptotic process
regulation of cell cycle
copper ion homeostasis
regulation of apoptosis involved in tissue homeostasis
regulation of nucleotide-binding oligomerization domain containing signaling pathway
nucleotide-binding oligomerization domain containing 1 signaling pathway
nucleotide-binding oligomerization domain containing 2 signaling pathway
protein K63-linked ubiquitination
positive regulation of canonical Wnt signaling pathway
protein linear polyubiquitination
execution phase of apoptosis
positive regulation of protein linear polyubiquitination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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